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Hinxton Hall

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| HINXTON 2004 - SCIENTIFIC PROGRAMME |

Please click to download a pdf version of the programme listed below.
Please choose from the following days or scroll down the list sequentially:


Wednesday 28th July

13:00 – 19:00 Arrival and registration
18:45 – 19:00 Introduction Stephen Moss

19:00 – 20:00 Plenary Lecture
Chair: Martin Bootman

Donald Gill (Baltimore, USA) Calcium entry mediated by SOCs and TRP channels: variations and enigma

20:00 - LATE - WELCOME PARTY

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Thursday 29th July

Session 1: Mitochondria - Chair: Rosario Donato
08:30 – 09:15 Keynote Lecture Rosario Rizzuto (Ferrara, It)
Mitochondrial Ca2+ signalling in cell life and death
09:15 – 09:45 Pontus Aspenstrom (Uppsala, S)
Rho GTPases in mitochondrial regulation

09:45 – 10:15

Mike Duchen (UK)
Calcium, mitochondria and oxidative stress in models of neurodegeneration
10:15 – 10:45 BREAK

Session 2: Cell Division - Chair: Daniela Pietrobon
10:45 – 11:15
Michael Whitaker
(Newcastle, UK)
Calcium signals in sperm, eggs and embryos
11:15 – 11:45 Howard Baylis (Cambridge, UK)
IP3 signalling in the C. elegans embryo

11:45 – 12:15

John Carroll (London, UK)
Ca2+ signalling in meiosis and mitosis

12:15 – 15:30 - LUNCH and Poster Session 1

14:15-15:15
SPONSORS - Technical Workshop
Session 3: CA2+ binding proteins - Chair: Rachel Wong
15:30 – 16:00
Bob Burgoyne (Liverpool, UK)
Neuronal calcium sensor proteins and the regulation of neurotransmission

16:00 – 16:30 Walter Chazin (Nashville, USA)
Structural mechanisms and target selectivity in EF-hand proteins

16:30 – 17:00

Reg Morgan (Oviedo, Es)
Evolutionary perspective on calcium binding protein families


Oral poster presentations - Chair: Jim Putney
17:00-17:15
Jan-Marek Weislogel (Heidelberg,
Germany) Calcium imaging using recombinant calcium probes in primary hippocampal neurons
17:15-17:30 Alexis Menteyne (Paris, Fr) NAADP signalling in mice pancreatic acinar cells: characterization of the calcium stores involved

17:30-17:45

Gabriele Ackermann (Zurich, Switzerland) S100A1-deficient mice display characteristics of hypertrophy and enhanced myocardial performance
17:45-18:00 David J Weber (Baltimore, USA) The calcium-dependent interaction of S100B with p53 inhibits the function of the tumor suppressor


FREE EVENING

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Friday 30th July


Session 4: Calcium and Disease - Chair: Volker Gerke

08:30 – 09:15 - Keynote Lecture Harvey Pollard (Bethesda, USA)
Annexin-dependent signaling pathways

09:15 – 09:45

Wei-Jen Tang (Chicago, USA)
Structural basis for the regulation of anthrax edema factor by calcium-calmodulin

09:45 – 10:15

Daniela Pietrobon (Padova, It)
Mutant calcium channels and migraine

10:15 – 10:45 BREAK
Session 5: Calcium Physiology - Chair: Claus Heizmann
10:45 – 11:15
Kathy Hajjar (New York, USA)
In vivo functions of annexin 2
11:15 – 11:45 Frank Wuytack (Leuven, B)
The Ca2+/Mn2+ pumps in the Golgi apparatus

11:45 – 12:15

Mitsuhiko Ikura (Toronto, Can)
Structural basis for IP3-mediated Ca2+ release from ER
12:15 – 15:30 - LUNCH and Poster Session 2


14:30– 15:30 - ECS GENERAL ASSEMBLY

Session 6: Cell signaling I - Chair: Joachim Krebs
15:30 – 16:00
Jim Putney (Raleigh, USA)
Novel mechanisms of calcium entry regulation
16:00 – 16:30 Alexei Tepikin (Liverpool, UK)
How to make local calcium signals: a lesson from polarized epithelial cells

16:30 – 17:00

Vincenzo Sorrentino (Siena, It)
A molecular approach to the organization of the calcium releasing machinery in the sarcoplasmic reticulum
 
Oral poster presentations - Chair: Jacques Haiech
17:00-17:15
Stéphanie Thebault (Villeneuve d'Ascq, Fr) Differential role of TRP channels in
Ca2+ entry and proliferation of primary
human prostate cancer epithelial cells
17:15-17:30 Peter Lockyer (Cambridge, UK) CAPRI is a novel sensor of Ca2+ entry revealing an analogue mode of Ca2+- dependent ras deactivation

17:30-17:45

Thomas Vogl (Muenster, Germany) Altered LPS signaling in S100A9-/- mice
17:45-18:00 Sacha Jensen (Oxford, UK) Calcium binding to fibrillin-1 TB-cbEGF domain pairs: new insights into microfibril organisation


CONFERENCE BANQUET

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Saturday 31st July


Session 7: Development and Neurobiology - Chair: Roland Pochet

09:00 – 09:45 - Keynote Lecture Rachel Wong (St.Louis, USA)
Calcium-dependent regulation of dendritic development in the retina

09:45 – 10:15

Nicholas Spitzer (San Diego, USA)
The frequency of calcium spikes specifies neurotransmitter expression in the spinal cord

10:15 – 10:45

Peter Mobbs (London, UK)
Calcium waves in the developing chick retina and retinal pigment epithelium

10:45 – 11:15 BREAK

Oral poster presentations - Chair: Alexei Tepikin

11:15-11:30 Catherine Leclerc /Marc Moreau
(Toulouse, Fr) A calcium-dependent pathway is involved in the formation of the embryonic kidney in Xenopus

11:30-11:45

Rod O'Connor (Cambridge, UK)
Cytosolic Ca2+ activates mitochondrial Ca2+ uptake

11:45-12:00

John Dedman (Ohio, USA) Targeted inhibition of Ca2+s/calmodulindependent
kinase II in cardiac myocytes of transgenic mice
12:00-12:15 Lorna Bailey (London, UK) Roles for annexin 1 and annexin 2 in post-endocytic sorting of EGFR

12.15 - 13.45 LUNCH

Session 8: Calcium and Disease III - Chair: Michael Berridge
13:45 – 14:15
Marie-France Bader (Strasbourg, Fr)
A role for lipids in the late stages of calcium-regulated exocytosis
14:15 – 14:45 Leon Lagnado (Cambridge, UK)
Calcium microdomains at the active zone

14:45 – 15:15

Xander Wehrens (New York, USA)
Ryanodine receptor dysfunction in cardiac disease

15:15 – 15:25 Closing remarks

15:25 Meeting ends

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Last up-dated June 9th 2004.