MBPhD Programme





Current Position:

Qualified 1999

PhD title:

Principal Supervisor:

Funding Source:

Jules Thorn Charitable Trust

Description of Project:


PubMed-accessible Publications:

Wagstaff,M.J ., Collaco-Moraes,Y., Aspey,B.S., Coffin,R.S., Harrison,M.J., Latchman,D.S., & de Belleroche,J.S. (1996) Focal cerebral ischaemia increases the levels of several classes of heat shock proteins and their corresponding mRNAs. Brain Res.Mol.Brain Res., 42, 236-244.

Coffin,R.S., Thomas,S.K., Thomas,N.S., Lilley,C.E., Pizzey,A.R., Griffiths,C.H., Gibb,B.J., Wagstaff,M.J., Inges,S.J., Binks,M.H., Chain,B.M., Thrasher,A.J., Rutault,K., & Latchman,D.S. (1998) Pure populations of transduced primary human cells can be produced using GFP expressing herpes virus vectors and flow cytometry. Gene Ther., 5, 718-722.

Wagstaff,M.J. , Smith,J., Collaco-Moraes,Y., de Belleroche,J.S., Voellmy,R., Coffin,R.S., & Latchman,D.S. (1998) Delivery of a constitutively active form of the heat shock factor using a virus vector protects neuronal cells from thermal or ischaemic stress but not from apoptosis. Eur.J.Neurosci., 10, 3343-3350.

Wagstaff,M.J ., Lilley,C.E., Smith,J., Robinson,M.J., Coffin,R.S., & Latchman,D.S. (1998) Gene transfer using a disabled herpes virus vector containing the EMCV IRES allows multiple gene expression in vitro and in vivo. Gene Ther., 5, 1566-1570.

Brar,B.K., Stephanou,A., Wagstaff,M.J., Coffin,R.S., Marber,M.S., Engelmann,G., & Latchman,D.S. (1999) Heat shock proteins delivered with a virus vector can protect cardiac cells against apoptosis as well as against thermal or hypoxic stress. J.Mol.Cell Cardiol., 31, 135-146.

Wagstaff,M.J. , Collaco-Moraes,Y., Smith,J., de Belleroche,J.S., Coffin,R.S., & Latchman,D.S. (1999) Protection of neuronal cells from apoptosis by Hsp27 delivered with a herpes simplex virus-based vector. J.Biol.Chem., %19;274, 5061-5069.

Wagstaff,M.J. , Raurell,A., & Perks,A.G. (2004) Multicentric extra-abdominal desmoid tumours. Br.J.Plast.Surg., 57, 362-365.

Milner,C.S., Wagstaff,M.J., & Rose,G.K. (2006) Compartment syndrome of multiple limbs: An unusual presentation. J Plast.Reconstr.Aesthet.Surg., 59, 1251-1252.

Wagstaff,M.J. , Shah,M., McGrouther,D.A., & Latchman,D.S. (2007) The heat shock proteins and plastic surgery. J Plast.Reconstr.Aesthet.Surg., 60, 974-982.