The core goal of the Centre for Cardiometabolic and Vascular Science is to understand the biological and molecular mechanisms that control a) lipid metabolism, inflammation and tissue damage in cardiometabolic and autoimmune diseases and b) the functions of blood vessels to translate this knowledge into novel therapies for cardiovascular and other human diseases.
A major focus of our research is understanding the transcriptional regulation of lipid metabolism and its impact on inflammatory pathways by lipid-activated nuclear receptors and how the angiogenic cytokine, VEGF, signals endothelial cells in blood vessels to mediate its vital functions in vertebrates.
For more details and interest in using these techniques, please contact the appropriate researcher.
NEWS AND EVENTS
Using machine learning approaches to identify serum metabolomic profiles that can predict subclinical atherosclerosis in patients with systemic lupus erythematosus. Click here to view the publication.
New biomarker to identify adolescent-lupus patients at increased cardiovascular disease risk: Researchers have found a biomarker that could identify patients with adolescent-lupus who are at greater risk of developing early cardiovascular diseases, such as stroke and heart attack. This biomarker is associated with increased inflammation and a worsened clinical outcome. LINK: UCL NEWS
The Division of Medicine runs a wide variety of short courses. Click here to find out more about the courses that are currently open for registration and also those that will be coming soon.