Surgical Oncology

This list excludes publications related to breast cancer

Primary malignant melanoma of the scrotum: a case report

Jayant S Vaidya, Sanjay A Pai, Roshni  F Chinoy:

Ind  J Urol, Sep 1995. 12 (1):26-27.  

Only the 6^th case reported in the world

Chemotherapy for carcinoma of the esophagus: A comparison of evidence from meta-analyses of randomized trials and of historical control studies.

MS Bhansali, JS Vaidya, RG Bhatt, PK Patil, RA Badwe, and PB Desai: 

Ann Oncol. Jun 1996; 7(4): 355-361.

Quoted in Minerva,  Br Med J, 6 Jul 1996; 313:62.PubMed, Abstract, PDF

Meta-analysis of 8 historical-control trials showed a 68% reduction in risk of death-> an effect of bias -> 12 contemporary randomised trials showed no benefit.

(Letter) The concept of scientific holism

J S Vaidya

Natl Med J Ind. Dec 1996; 9(6): 299-300

(Letter) Does CARET reduce lung cancer and heart disease?

J S Vaidya.

Natl Med J Ind. Jan 1997; 10(1):47.

(Letter) Multimodality therapy for adenocarcinoma of esophagus

R A Badwe, J S Vaidya, M S Bhansali.

NewEngl J Med. 30 Jan 1997; 336: 374-375 WWW, HTML,

We have shown in a meta-analysis of 12 randomised trials that chemotherapy does not improve survival. Current evidence does not support neoadjuvant chemotherapy for oesophageal cancer.

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(Letter) Molecular staging of cancer.

M Baum, JS Vaidya.

The Lancet 27 Sept 1997; 350(9082):962.

Fraction of Normal remaining life: a new method of expressing survival in cancer

JS Vaidya, I Mittra.

BMJ 7 Jun 1997; 314:1682-1684.

Quoted in Cancer Topics, Oct-Nov 1997;10(8):5,

Responses in BMJ 22 Nov 1997; 1375-76. WWW, PDF       

A novel way to answer ‘what is my chance of cure?’

(Letter) Spiral CT  and Lung cancer biology.

Jayant S Vaidya, Michael Baum,

The Lancet 18 July 1998; 352:236 WWW, HTML, PDF,

Spiral CT perhaps detects cancers that would never otherwise become symptomatic-also, normal homeostasis may involve anti-angiogenic processes much more widely.

(Letter) Randomised trials are not unethical.

Jayant S Vaidya, Michael Baum,

The Lancet 15 May 1999;353:1714., PDF

 (Letter) Does screening really reduce mortality?

Jayant S Vaidya, Michael Baum,

BMJ 4 Sep 1999; 319:642; HTML 

Using the same figures, one can also conclude that screening may have caused up to 2900 extra deaths due to cervival cancer in 1997.

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(abstract) Colorectal Cancer Follow-up: 5 Years' Experience of Routine CT Scanning.

Scott, M A. Vaidya, J S. Lock, R. Ingham Clark, C L. Mukhtar, H.

Colorectal Disease July 2002; Supplement.1:51,.

(Letter) Preoperative radiotherapy for soft tissue sarcoma- correct interpretation of the randomised trial.

JS Vaidya FF Palazzo

The Lancet  14 Dec 2002; 360:1988-89.HTML,  PDF

Preoperative radiotherapy may indeed have a survival benefit but the trial does have enough power to detect it.