UK Parkinson's Disease Consortium - UKPDC
- Principal Investigators
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- Clinical Neuroscience
- Clinical Studies
- Drosophila Genetics
- Molecular Biology and Biochemistry
- Molecular Neuropathology
- Neurological Biochemistry
- Neurological Signalling
- Protein Phosphorylation
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Public lecture: The autophagy signaling network, c-‐myc and pathology: don't mess with the cell cycle!
You are invited to a public lecture by Francesco Cecconi, an eminent scientist in the field of autophagy and neurodegeneration, on Thursday the 25th of April at 17:00, in the lecture theatre of 33 Queen Square, University College Hospital London, WC1N. The lecture will be followed by a general discussion with drinks and food. More...
Have you ever wondered how scientists research the brain? Have you wondered who digs through that beautiful mass of grey matter between our ears to understand how it works and why it stops working? Meet the Neurodegenerative Diseases Initiative. Funded by the Wellcome Trust and MRC, this team of scientists from around the globe investigates Alzheimer's, Parkinson's and Motor Neuron Diseases. The team is on the hunt for understanding and treatments for brain diseases. More...
The "Degenerating Brains" public symposium was held on the 13th March 2013, as part of Brain Awareness Week. Around 250 people showed up to hear Professors John Hardy (UCL), Chris Shaw (KCL) and David Rubinsztein (Cambridge) discuss new discoveries in neurodegenerative diseases and how they might impact drug treatment. More...
New research, published in Neuron, gives insight into how single mutations in the VCP gene cause a range of neurological conditions including a form of dementia called Inclusion Body Myopathy, Paget’s Disease of the Bone and Frontotemporal Dementia (IBMPFD), and the motor neuron disease Amyotrophic Lateral Sclerosis (ALS). More...
You are invited to an evening (13th March 2013) exploring the very latest in cutting edge research into neurodegenerative diseases. Supported by the Wellcome Trust, scientists investigating Alzheimer's, Parkinson's and Motor Neuron disease will explain how our understanding of these disorders is changing in the light of new discoveries in genetics and cell biology, and how these discoveries impact on developing new drugs for these diseases.
18.00 Welcome and introduction
18.10 Lectures commence
(MJFF Research Fellow)
I graduated in Pharmaceutical Biotechnology at the University of Milan and, to obtain my degree, I worked at the Mario Negri Institute for Pharmacological Research for 18 months on a project concerning the description of the synthetic peptide PrP82-146 as an in vitro model for prion amyloid. After graduation I remained at the Mario Negri Institute as research fellow in the lab. of Protein Chemistry and Biochemistry. In January 2006 I started my PhD with the Open University and I graduated in April 2010. For my PhD project I worked with Abeta amyloid investigating Abeta-induced neuronal toxicity and confirming that Abeta peptides, when appropriately folded, can impair neuronal viability following protein-mediated “docking” onto cell membranes. The aim of my study was to identify membrane proteins which might have a role in triggering Abeta-induced toxicity after binding to Abeta oligomers. In March 2010 I joined the Department of Molecular Neuroscience as associate research fellow under the supervision of Dr. Lewis working on a project concerning the characterization of fibroblasts from PD patients with mutations in the LRRK2 protein, with specific interest for the mTOR and the TNFa signalling pathways.
Page last modified on 20 mar 13 16:56