UK Parkinson's Disease Consortium - UKPDC
- Principal Investigators
- Research Groups
- Cell Physiology
- Clinical Neuroscience
- Clinical Studies
- Drosophila Genetics
- Molecular Biology and Biochemistry
- Molecular Neuropathology
- Neurological Biochemistry
- Neurological Signalling
- Protein Phosphorylation
- Contact us
One of the UK Parkinson's Disease Consortium Principal Investigators, Prof John Hardy, has been awarded the 2015 Robert A. Pritzker Prize for his leadership in Parkinson's genetics research. The award was presented by Michael J. Fox at a ceremony in New York on April 15. From the Michael J. Fox Foundation website: More...
Webcast of the presentation entitled ‘Advances in Genetic Understanding of Parkinson's Disease’ given by Nicholas Wood (University College London, United Kingdom) presented at the Biochemical Society Hot Topic event, PINK1-Parkin Signalling in Parkinson’s Disease and Beyond, held in December 2014. More...
A study published in Brain, led by researchers
at UCL Institute of Neurology, has shown that genetic mutations which
cause a decrease in dopamine
production in the brain and lead to a form of childhood-onset Dystonia,
also play a role in the development of Parkinson’s disease.
The new Leonard Wolfson Experimental Neurology Centre (LWENC) has opened for clinical studies and trials
In this paper Claudia Manzoni studies how fibroblast
cells from people with Parkinson’s disease caused by mutations in LRRK2
react to starvation. Although the changes are quite subtle, there are
differences between the way that fibroblasts that contain mutant LRRK2
respond to being starved – suggesting that there may be changes in the
way that these cells regulate a key process called autophagy (a term
which comes from the greek meaning to eat yourself, and is one of the
ways that cells get rid of waste and recycle proteins and organellles).
Rita Louro Guerreiro
I received my B.Sc. in Biomedical Sciences in 2002, my M.S. degree in Biomolecular Methods in 2005, and more recently (2010) my PhD (Hons) from the Coimbra University in Portugal. My PhD work was supervised by Dr. John Hardy and Dr. Catarina Oliveira and was conducted at the Laboratory of Neurogenetics, NIA, NIH, USA. During this time I studied the genetics of dementia, mainly searching for new mutations and new genes underlying Alzheimer’s disease and Frontotemporal dementia. I started working in the Department of Molecular Neuroscience, IoN, UCL in 2010 as a postdoctoral research fellow. My current research interests include the analysis of genetic variability in several neurological diseases (mainly Parkinson and Alzheimer diseases) and more broadly, trying to understand how genetic variants affect the disease process at the molecular level.
Link to publications
Page last modified on 20 mar 13 16:38