Nicholas Wood

(Principal Investigator)

Prof Nick Wood’s chief interests are the genetic variants which contribute to nervous system function and dysfunction. Over the last few years the laboratory has contributed to the finding of a number of genes which when mutated cause Parkinson's disease and other neurological conditions. Following on from these discoveries he has built a group focussed on understanding the molecular pathogenesis of PD. This involves molecular and cellular biology and live cell imaging. One of the major challenges facing neuroscience is the genetic basis of normal and abnormal function. Over the past few years this lab and colleagues (within and outside UCL) have built a programme of research based around haplotype tagging of the human genome. Currently he is directly involved in 2 genome wide associations studies focussed on two common neurological diseases (Epilepsy and Parkinsons Disease).

Nick qualified in medicine from the University of Birmingham. He went on to take a PhD in Cambridge. He was elected to the Fellowship of the Academy of Medical Science in 2004 and to senior investigator of the NIHR in 2008. He is currently Galton Professor of Genetics, a Consultant Neurologist and neuroscience programme director for UCLH NIHR Biomedical Research Centre (BRC).

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Contact details

Lab website

Link to Publications

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Number of items: 455.

2013

Cleeter, MW and Chau, KY and Gluck, C and Mehta, A and Hughes, DA and Duchen, M and Wood, NW and Hardy, J and Mark Cooper, J and Schapira, AH (2013) Glucocerebrosidase inhibition causes mitochondrial dysfunction and free radical damage. Neurochem Int , 62 (1) 1 - 7. 10.1016/j.neuint.2012.10.010.
An open access publication

Duran, R and Mencacci, NE and Angeli, AV and Shoai, M and Deas, E and Houlden, H and Mehta, A and Hughes, D and Cox, TM and Deegan, P and Schapira, AH and Lees, AJ and Limousin, P and Jarman, PR and Bhatia, KP and Wood, NW and Hardy, J and Foltynie, T (2013) The glucocerobrosidase E326K variant predisposes to Parkinson's disease, but does not cause Gaucher's disease. Mov Disord , 28 (2) 232 - 236. 10.1002/mds.25248.

Holmans, P and Moskvina, V and Jones, L and Sharma, M and International Parkinson's Disease Genomics Consortium, and Vedernikov, A and Buchel, F and Sadd, M and Bras, JM and Bettella, F and Nicolaou, N and Simón-Sánchez, J and Mittag, F and Gibbs, JR and Schulte, C and Durr, A and Guerreiro, R and Hernandez, D and Brice, A and Stefánsson, H and Majamaa, K and Gasser, T and Heutink, P and Wood, NW and Martinez, M and Singleton, AB and Nalls, MA and Hardy, J and Morris, HR and Williams, NM (2013) A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease. Hum Mol Genet , 22 (5) 1039 - 1049. 10.1093/hmg/dds492.

Holmström, KM and Marina, N and Baev, AY and Wood, NW and Gourine, AV and Abramov, AY (2013) Signalling properties of inorganic polyphosphate in the mammalian brain. Nat Commun , 4 1362 - ?. 10.1038/ncomms2364.
An open access publication

Koutsis, G and Pandraud, A and Karadima, G and Panas, M and Reilly, MM and Floroskufi, P and Wood, NW and Houlden, H (2013) Mutational analysis of PMP22, EGR2, LITAF and NEFL in Greek Charcot-Marie-Tooth type 1 patients. CLINICAL GENETICS , 83 (4) 388 - 391. 10.1111/j.1399-0004.2012.01910.x.

Koutsis, G and Pandraud, A and Karadima, G and Panas, M and Reilly, MM and Floroskufi, P and Wood, NW and Houlden, H (2013) Mutational analysis of PMP22, EGR2, LITAF and NEFL in Greek Charcot-Marie-Tooth type 1 patients. Clin Genet , 83 (4) 388 - 391. 10.1111/j.1399-0004.2012.01910.x.

LeishGEN Consortium, and Wellcome Trust Case Control Consortium 2, and Fakiola, M and Strange, A and Cordell, HJ and Miller, EN and Pirinen, M and Su, Z and Mishra, A and Mehrotra, S and Monteiro, GR and Band, G and Bellenguez, C and Dronov, S and Edkins, S and Freeman, C and Giannoulatou, E and Gray, E and Hunt, SE and Lacerda, HG and Langford, C and Pearson, R and Pontes, NN and Rai, M and Singh, SP and Smith, L and Sousa, O and Vukcevic, D and Bramon, E and Brown, MA and Casas, JP and Corvin, A and Duncanson, A and Jankowski, J and Markus, HS and Mathew, CG and Palmer, CN and Plomin, R and Rautanen, A and Sawcer, SJ and Trembath, RC and Viswanathan, AC and Wood, NW and Wilson, ME and Deloukas, P and Peltonen, L and Christiansen, F and Witt, C and Jeronimo, SM and Sundar, S and Spencer, CC and Blackwell, JM and Donnelly, P (2013) Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis. Nat Genet , 45 (2) 208 - 213. 10.1038/ng.2518.

Sheerin, UM and Stamelou, M and Charlesworth, G and Shiner, T and Spacey, S and Valente, EM and Wood, NW and Bhatia, KP (2013) Migraine with aura as the predominant phenotype in a family with a PRRT2 mutation. J Neurol , 260 (2) 656 - 660. 10.1007/s00415-012-6747-4.

Wood-Kaczmar, A and Deas, E and Wood, NW and Abramov, AY (2013) The role of the mitochondrial NCX in the mechanism of neurodegeneration in Parkinson's disease. Adv Exp Med Biol , 961 241 - 249. 10.1007/978-1-4614-4756-6_20.

2012

Charlesworth, G and Gandhi, S and Bras, JM and Barker, RA and Burn, DJ and Chinnery, PF and Gentleman, SM and Guerreiro, R and Hardy, J and Holton, JL and Lees, A and Morrison, K and Sheerin, UM and Williams, N and Morris, H and Revesz, T and Wood, NW (2012) Tau acts as an independent genetic risk factor in pathologically proven PD. Neurobiol Aging , 33 (4) 838.e7 - 838.11. 10.1016/j.neurobiolaging.2011.11.001.

Charlesworth, G and Plagnol, V and Holmström, KM and Bras, J and Sheerin, UM and Preza, E and Rubio-Agusti, I and Ryten, M and Schneider, SA and Stamelou, M and Trabzuni, D and Abramov, AY and Bhatia, KP and Wood, NW (2012) Mutations in ANO3 cause dominant craniocervical dystonia: ion channel implicated in pathogenesis. Am J Hum Genet , 91 (6) 1041 - 1050. 10.1016/j.ajhg.2012.10.024.

Cremades, N and Cohen, SI and Deas, E and Abramov, AY and Chen, AY and Orte, A and Sandal, M and Clarke, RW and Dunne, P and Aprile, FA and Bertoncini, CW and Wood, NW and Knowles, TP and Dobson, CM and Klenerman, D (2012) Direct observation of the interconversion of normal and toxic forms of α-synuclein. Cell , 149 (5) 1048 - 1059. 10.1016/j.cell.2012.03.037.

Fitzgerald, JC and Camprubi, MD and Dunn, L and Wu, HC and Ip, NY and Kruger, R and Martins, LM and Wood, NW and Plun-Favreau, H (2012) Phosphorylation of HtrA2 by cyclin-dependent kinase-5 is important for mitochondrial function. Cell Death Differ , 19 (2) 257 - 266. 10.1038/cdd.2011.90.

Gandhi, S and Vaarmann, A and Yao, Z and Duchen, MR and Wood, NW and Abramov, AY (2012) Dopamine induced neurodegeneration in a PINK1 model of Parkinson's disease. PLoS One , 7 (5) , Article e37564 . 10.1371/journal.pone.0037564.
An open access publication. A version is also available from UCL Discovery.

Gardiner, AR and Bhatia, KP and Stamelou, M and Dale, RC and Kurian, MA and Schneider, SA and Wali, GM and Counihan, T and Schapira, AH and Spacey, SD and Valente, E-M and Silveira-Moriyama, L and Teive, HAG and Raskin, S and Sander, JW and Lees, A and Warner, T and Kullmann, DM and Wood, NW and Hanna, M and Houlden, H (2012) PRRT2 gene mutations From paroxysmal dyskinesia to episodic ataxia and hemiplegic migraine. NEUROLOGY , 79 (21) 2115 - 2121.

Gardiner, AR and Bhatia, KP and Stamelou, M and Dale, RC and Kurian, MA and Schneider, SA and Wali, GM and Counihan, T and Schapira, AH and Spacey, SD and Valente, EM and Silveira-Moriyama, L and Teive, HA and Raskin, S and Sander, JW and Lees, A and Warner, T and Kullmann, DM and Wood, NW and Hanna, M and Houlden, H (2012) PRRT2 gene mutations: from paroxysmal dyskinesia to episodic ataxia and hemiplegic migraine. Neurology , 79 (21) 2115 - 2121. 10.1212/WNL.0b013e3182752c5a.

Gegg, ME and Burke, D and Heales, SJ and Cooper, JM and Hardy, J and Wood, NW and Schapira, AH (2012) Glucocerebrosidase deficiency in substantia nigra of parkinson disease brains. Ann Neurol , 72 (3) 455 - 463. 10.1002/ana.23614.

Giunti, P and Houlden, H and Gardner-Thorpe, C and Worth, PF and Johnson, J and Hilton, DA and Revesz, T and Davis, MB and Wood, NW (2012) Spinocerebellar ataxia type 11. In: UNSPECIFIED (521 - 534).

Hersheson, J and Mencacci, NE and Davis, M and Macdonald, N and Trabzuni, D and Ryten, M and Pittman, A and Paudel, R and Kara, E and Fawcett, K and Plagnol, V and Bhatia, KP and Medlar, AJ and Stanescu, HC and Hardy, J and Kleta, R and Wood, NW and Houlden, H (2012) Mutations in the autoregulatory domain of β-tubulin 4a cause hereditary dystonia. Ann Neurol 10.1002/ana.23832.

International Stroke Genetics Consortium (ISGC), and Wellcome Trust Case Control Consortium 2 (WTCCC2), and Bellenguez, C and Bevan, S and Gschwendtner, A and Spencer, CC and Burgess, AI and Pirinen, M and Jackson, CA and Traylor, M and Strange, A and Su, Z and Band, G and Syme, PD and Malik, R and Pera, J and Norrving, B and Lemmens, R and Freeman, C and Schanz, R and James, T and Poole, D and Murphy, L and Segal, H and Cortellini, L and Cheng, YC and Woo, D and Nalls, MA and Müller-Myhsok, B and Meisinger, C and Seedorf, U and Ross-Adams, H and Boonen, S and Wloch-Kopec, D and Valant, V and Slark, J and Furie, K and Delavaran, H and Langford, C and Deloukas, P and Edkins, S and Hunt, S and Gray, E and Dronov, S and Peltonen, L and Gretarsdottir, S and Thorleifsson, G and Thorsteinsdottir, U and Stefansson, K and Boncoraglio, GB and Parati, EA and Attia, J and Holliday, E and Levi, C and Franzosi, MG and Goel, A and Helgadottir, A and Blackwell, JM and Bramon, E and Brown, MA and Casas, JP and Corvin, A and Duncanson, A and Jankowski, J and Mathew, CG and Palmer, CN and Plomin, R and Rautanen, A and Sawcer, SJ and Trembath, RC and Viswanathan, AC and Wood, NW and Worrall, BB and Kittner, SJ and Mitchell, BD and Kissela, B and Meschia, JF and Thijs, V and Lindgren, A and Macleod, MJ and Slowik, A and Walters, M and Rosand, J and Sharma, P and Farrall, M and Sudlow, CL and Rothwell, PM and Dichgans, M and Donnelly, P and Markus, HS (2012) Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke. Nat Genet , 44 (3) 328 - 333. 10.1038/ng.1081.

Keller, MF and Saad, M and Bras, J and Bettella, F and Nicolaou, N and Simón-Sánchez, J and Mittag, F and Büchel, F and Sharma, M and Gibbs, JR and Schulte, C and Moskvina, V and Durr, A and Holmans, P and Kilarski, LL and Guerreiro, R and Hernandez, DG and Brice, A and Ylikotila, P and Stefánsson, H and Majamaa, K and Morris, HR and Williams, N and Gasser, T and Heutink, P and Wood, NW and Hardy, J and Martinez, M and Singleton, AB and Nalls, MA and International Parkinson's Disease Genomics Consortium (IPDGC), and Wellcome Trust Case Control Consortium 2 (WTCCC2), (2012) Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease. Hum Mol Genet , 21 (22) 4996 - 5009. 10.1093/hmg/dds335.

Kilarski, LL and Pearson, JP and Newsway, V and Majounie, E and Knipe, MDW and Misbahuddin, A and Chinnery, PF and Burn, DJ and Clarke, CE and Marion, M-H and Lewthwaite, AJ and Nicholl, DJ and Wood, NW and Morrison, KE and Williams-Gray, CH and Evans, JR and Sawcer, SJ and Barker, RA and Wickremaratchi, MM and Ben-Shlomo, Y and Williams, NM and Morris, HR (2012) Systematic Review and UK-Based Study of PARK2 (parkin), PINK1, PARK7 (DJ-1) and LRRK2 in early-onset Parkinson's disease. MOVEMENT DISORDERS , 27 (12) 1522 - 1529. 10.1002/mds.25132.

Kojovic, M and Sheerin, UM and Rubio-Agusti, I and Saha, A and Bras, J and Gibbons, V and Palmer, R and Houlden, H and Hardy, J and Wood, NW and Bhatia, KP (2012) Young-onset parkinsonism due to homozygous duplication of α-synuclein in a consanguineous family. Mov Disord , 27 (14) 1827 - 1829. 10.1002/mds.25199.

Koutsis, G and Karadima, G and Pandraud, A and Sweeney, MG and Paudel, R and Houlden, H and Wood, NW and Panas, M (2012) Genetic screening of Greek patients with Huntington’s disease phenocopies identifies an SCA8 expansion. J Neurol , 259 (9) 1874 - 1878. 10.1007/s00415-012-6430-9.

Koutsis, G and Pandraud, A and Polke, JM and Wood, NW and Panas, M and Karadima, G and Houlden, H (2012) Novel peripheral myelin protein 22 (PMP22) micromutations associated with variable phenotypes in Greek patients with Charcot-Marie-Tooth disease. Brain , 135 (Pt 8) e217 - 6. 10.1093/brain/aws034.

Koutsis, G and Pemble, S and Sweeney, MG and Paudel, R and Wood, NW and Panas, M and Kladi, A and Houlden, H (2012) Analysis of spinocerebellar ataxias due to expanded triplet repeats in Greek patients with cerebellar ataxia. In: EUROPEAN JOURNAL OF NEUROLOGY. (pp. 731 - 731).

Koutsis, G and Pemble, S and Sweeney, MG and Paudel, R and Wood, NW and Panas, M and Kladi, A and Houlden, H (2012) Analysis of spinocerebellar ataxias due to expanded triplet repeats in Greek patients with cerebellar ataxia. J Neurol Sci , 318 (1-2) 178 - 180. 10.1016/j.jns.2012.03.019.

Lill, CM and Roehr, JT and McQueen, MB and Kavvoura, FK and Bagade, S and Schjeide, B-MM and Schjeide, LM and Meissner, E and Zauft, U and Allen, NC and Liu, T and Schilling, M and Anderson, KJ and Beecham, G and Berg, D and Biernacka, JM and Brice, A and DeStefano, AL and Do, CB and Eriksson, N and Factor, SA and Farrer, MJ and Foroud, T and Gasser, T and Hamza, T and Hardy, JA and Heutink, P and Hill-Burns, EM and Klein, C and Latourelle, JC and Maraganore, DM and Martin, ER and Martinez, M and Myers, RH and Nalls, MA and Pankratz, N and Payami, H and Satake, W and Scott, WK and Sharma, M and Singleton, AB and Stefansson, K and Toda, T and Tung, JY and Vance, J and Wood, NW and Zabetian, CP and Young, P and Tanzi, RE and Khoury, MJ and Zipp, F and Lehrach, H and Ioannidis, JPA and Bertram, L and Parkinson's, GE and IPDGC, and Consortium, PDGWAS and WTCCC2, (2012) Comprehensive Research Synopsis and Systematic Meta-Analyses in Parkinson's Disease Genetics: The PDGene Database. PLOS GENETICS , 8 (3) , Article ARTN e1002548. 10.1371/journal.pgen.1002548.
An open access publication

McNeill, A and Duran, R and Proukakis, C and Bras, J and Hughes, D and Mehta, A and Hardy, J and Wood, NW and Schapira, AH (2012) Hyposmia and cognitive impairment in Gaucher disease patients and carriers. Mov Disord , 27 (4) 526 - 532. 10.1002/mds.24945.

Mittag, F and Büchel, F and Saad, M and Jahn, A and Schulte, C and Bochdanovits, Z and Simón-Sánchez, J and Nalls, MA and Keller, M and Hernandez, DG and Gibbs, JR and Lesage, S and Brice, A and Heutink, P and Martinez, M and Wood, NW and Hardy, J and Singleton, AB and Zell, A and Gasser, T and Sharma, M and International Parkinson’s Disease Genomics Consortium, (2012) Use of support vector machines for disease risk prediction in genome-wide association studies: concerns and opportunities. Hum Mutat , 33 (12) 1708 - 1718. 10.1002/humu.22161.

Plagnol, V and Curtis, J and Epstein, M and Mok, KY and Stebbings, E and Grigoriadou, S and Wood, NW and Hambleton, S and Burns, SO and Thrasher, AJ and Kumararatne, D and Doffinger, R and Nejentsev, S (2012) A robust model for read count data in exome sequencing experiments and implications for copy number variant calling. Bioinformatics , 28 (21) 2747 - 2754. 10.1093/bioinformatics/bts526.
An open access publication

Plun-Favreau, H and Burchell, VS and Holmström, KM and Yao, Z and Deas, E and Cain, K and Fedele, V and Moisoi, N and Campanella, M and Miguel Martins, L and Wood, NW and Gourine, AV and Abramov, AY (2012) HtrA2 deficiency causes mitochondrial uncoupling through the F₁F₀-ATP synthase and consequent ATP depletion. Cell Death Dis , 3 e335 - ?. 10.1038/cddis.2012.77.
An open access publication

Proukakis, C and Moore, D and Labrum, R and Wood, NW and Houlden, H (2012) HEREDITARY SPASTIC PARAPLEGIA CAUSED BY SPASTIN (SPAST, SPG4) MUTATIONS IS FOUND MORE OFTEN IN MALES: REPORT OF NOVEL MUTATIONS FROM ONE CENTRE, AND REVIEW OF PUBLISHED LITERATURE. In: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY.

Sailer, A and Scholz, SW and Gibbs, JR and Tucci, A and Johnson, JO and Wood, NW and Plagnol, V and Hummerich, H and Ding, J and Hernandez, D and Hardy, J and Federoff, HJ and Traynor, BJ and Singleton, AB and Houlden, H (2012) Exome sequencing in an SCA14 family demonstrates its utility in diagnosing heterogeneous diseases. Neurology , 79 (2) 127 - 131. 10.1212/WNL.0b013e31825f048e.
An open access publication

Simon-Sanchez, J and Kilarski, LL and Nalls, MA and Martinez, M and Schulte, C and Holmans, P and Gasser, T and Hardy, J and Singleton, AB and Wood, NW and Brice, A and Heutink, P and Williams, N and Morris, HR and Conso, IPDG and Consor, WTCC (2012) Cooperative Genome-Wide Analysis Shows Increased Homozygosity in Early Onset Parkinson's Disease. PLOS ONE , 7 (3) , Article e28787. 10.1371/journal.pone.0028787.
An open access publication. A version is also available from UCL Discovery.

Stamelou, M and Mencacci, NE and Cordivari, C and Batla, A and Wood, NW and Houlden, H and Hardy, J and Bhatia, KP (2012) Myoclonus-dystonia syndrome due to tyrosine hydroxylase deficiency. Neurology , 79 (5) 435 - 441. 10.1212/WNL.0b013e318261714a.
An open access publication

Strange, A and Riley, BP and Spencer, CCA and Morris, DW and Pirinen, M and O'Dushlaine, CT and Su, Z and Maher, BS and Freeman, C and Cormican, P and Bellenguez, C and Kenny, EM and Band, G and Wormley, B and Donohoe, G and Dilthey, A and Moutsianas, L and Quinn, E and Edkins, S and Judge, R and Coleman, K and Hunt, S and Tropea, D and Roche, S and Cummings, L and Kelleher, E and McKeon, P and Dinan, T and McDonald, C and Murphy, KC and O'Callaghan, E and O'Neill, FA and Waddington, JL and Walsh, D and Giannoulatou, E and Langford, C and Deloukas, P and Gray, E and Dronov, S and Potter, S and Pearson, R and Vukcevic, D and Tashakkori-Ghanbaria, A and Blackwell, JM and Bramon, E and Brown, MA and Casas, JP and Duncanson, A and Jankowski, J and Markus, HS and Mathew, CG and Palmer, CNA and Plomin, R and Rautanen, A and Sawcer, SJ and Trembath, RC and Viswanathan, AC and Wood, NW and Stone, J and Scolnick, E and Purcell, S and Sklar, P and Ripke, S and Walters, J and Owen, MJ and O'Donovan, MC and Peltonen, L and McVean, G and Kendler, KS and Gill, M and Donnelly, P and Corvin, A and Conso, ISG and Consortium, SGENE and Psychiat, SWG and Consor, WTCC (2012) Genome-Wide Association Study Implicates HLA-C*01:02 as a Risk Factor at the Major Histocompatibility Complex Locus in Schizophrenia. BIOLOGICAL PSYCHIATRY , 72 (8) 620 - 628. 10.1016/j.biopsych.2012.05.035.

Tsoi, LC and Spain, SL and Knight, J and Ellinghaus, E and Stuart, PE and Capon, F and Ding, J and Li, Y and Tejasvi, T and Gudjonsson, JE and Kang, HM and Allen, MH and McManus, R and Novelli, G and Samuelsson, L and Schalkwijk, J and Ståhle, M and Burden, AD and Smith, CH and Cork, MJ and Estivill, X and Bowcock, AM and Krueger, GG and Weger, W and Worthington, J and Tazi-Ahnini, R and Nestle, FO and Hayday, A and Hoffmann, P and Winkelmann, J and Wijmenga, C and Langford, C and Edkins, S and Andrews, R and Blackburn, H and Strange, A and Band, G and Pearson, RD and Vukcevic, D and Spencer, CC and Deloukas, P and Mrowietz, U and Schreiber, S and Weidinger, S and Koks, S and Kingo, K and Esko, T and Metspalu, A and Lim, HW and Voorhees, JJ and Weichenthal, M and Wichmann, HE and Chandran, V and Rosen, CF and Rahman, P and Gladman, DD and Griffiths, CE and Reis, A and Kere, J and Collaborative Association Study of Psoriasis (CASP), and Genetic Analysis of Psoriasis Consortium, and Psoriasis Association Genetics Extension, and Wellcome Trust Case Control Consortium 2, and Nair, RP and Franke, A and Barker, JN and Abecasis, GR and Elder, JT and Trembath, RC (2012) Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. Nat Genet , 44 (12) 1341 - 1348. 10.1038/ng.2467.

Tucci, A and Charlesworth, G and Sheerin, UM and Plagnol, V and Wood, NW and Hardy, J (2012) Study of the genetic variability in a Parkinson's Disease gene: EIF4G1. Neurosci Lett , 518 (1) 19 - 22. 10.1016/j.neulet.2012.04.033.

2011

Abramov, AY and Gegg, M and Grunewald, A and Wood, NW and Klein, C and Schapira, AHV (2011) Bioenergetic Consequences of PINK1 Mutations in Parkinson Disease. PLOS ONE , 6 (10) , Article e25622. 10.1371/journal.pone.0025622.
An open access publication. A version is also available from UCL Discovery.

Deas, E and Plun-Favreau, H and Gandhi, S and Desmond, H and Kjaer, S and Loh, SHY and Renton, AEM and Harvey, RJ and Whitworth, AJ and Martins, LM and Abramov, AY and Wood, NW (2011) PINK1 cleavage at position A103 by the mitochondrial protease PARL. Human Molecular Genetics , 20 (5) pp. 867-879. 10.1093/hmg/ddq526.
An open access version is available from UCL Discovery

Deas, E and Wood, NW and Plun-Favreau, H (2011) Mitophagy and Parkinson's disease: The PINK1-parkin link. BBA-MOL CELL RES , 1813 (4) 623 - 633. 10.1016/j.bbamcr.2010.08.007.

Devine, MJ and Plun-Favreau, H and Wood, NW (2011) Parkinson's disease and cancer: two wars, one front. NAT REV CANCER , 11 (11) 812 - +. 10.1038/nrc3150.

Evans, DM and Spencer, CCA and Pointon, JJ and Su, Z and Harvey, D and Kochan, G and Opperman, U and Dilthey, A and Pirinen, M and Stone, MA and Appleton, L and Moutsianis, L and Leslie, S and Wordsworth, T and Kenna, TJ and Karaderi, T and Thomas, GP and Ward, MM and Weisman, MH and Farrar, C and Bradbury, LA and Danoy, P and Inman, RD and Maksymowych, W and Gladman, D and Rahman, P and Morgan, A and Marzo-Ortega, H and Bowness, P and Gaffney, K and Gaston, JSH and Smith, M and Bruges-Armas, J and Couto, AR and Sorrentino, R and Paladini, F and Ferreira, MA and Xu, HJ and Liu, Y and Jiang, L and Lopez-Larrea, C and Diaz-Pena, R and Lopez-Vazquez, A and Zayats, T and Band, G and Bellenguez, C and Blackburn, H and Blackwell, JM and Bramon, E and Bumpstead, SJ and Casas, JP and Corvin, A and Craddock, N and Deloukas, P and Dronov, S and Duncanson, A and Edkins, S and Freeman, C and Gillman, M and Gray, E and Gwilliam, R and Hammond, N and Hunt, SE and Jankowski, J and Jayakumar, A and Langford, C and Liddle, J and Markus, HS and Mathew, CG and McCann, OT and McCarthy, MI and Palmer, CNA and Peltonen, L and Plomin, R and Potter, SC and Rautanen, A and Ravindrarajah, R and Ricketts, M and Samani, N and Sawcer, SJ and Strange, A and Trembath, RC and Viswanathan, AC and Waller, M and Weston, P and Whittaker, P and Widaa, S and Wood, NW and McVean, G and Reveille, JD and Wordsworth, BP and Brown, MA and Donnelly, P and Australo-Anglo-Amer Spondyloarthri, and Wellcome Trust Case Control Consor, and Spondyloarthrit Res Consortium Can, (2011) Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. NAT GENET , 43 (8) 761 - U67. 10.1038/ng.873.

Ling, H and Polke, JM and Sweeney, MG and Haworth, A and Sandford, CA and Heales, SJR and Wood, NW and Davis, MB and Lees, AJ (2011) An Intragenic Duplication in Guanosine Triphosphate Cyclohydrolase-1 Gene in a Dopa-Responsive Dystonia Family. MOVEMENT DISORD , 26 (5) 905 - 909. 10.1002/mds.23593.

Nalls, MA and Plagnol, V and Hernandez, DG and Sharma, M and Sheerin, UM and Saad, M and Simon-Sanchez, J and Schulte, C and Lesage, S and Sveinbjornsdottir, S and Arepalli, S and Barker, R and Ben-Shlomo, Y and Berendse, HW and Berg, D and Bhatia, K and de Bie, RMA and Biffi, A and Bloem, B and Bochdanovits, Z and Bonin, M and Bras, JM and Brockmann, K and Brooks, J and Burn, DJ and Charlesworth, G and Chen, HL and Chinnery, PF and Chong, S and Clarke, CE and Cookson, MR and Cooper, JM and Corvol, JC and Counsell, C and Damier, P and Dartigues, JF and Deloukas, P and Deuschl, G and Dexter, DT and van Dijk, KD and Dillman, A and Durif, F and Durr, A and Edkins, S and Evans, JR and Foltynie, T and Gao, JJ and Gardner, M and Gibbs, JR and Goate, A and Gray, E and Guerreiro, R and Gustafsson, O and Harris, C and van Hilten, JJ and Hofman, A and Hollenbeck, A and Holton, J and Hu, M and Huang, XM and Huber, H and Hudson, G and Hunt, SE and Huttenlocher, J and Illig, T and Jonsson, PV and Lambert, JC and Langford, C and Lees, A and Lichtner, P and Limousin, P and Lopez, G and Lorenz, D and McNeill, A and Moorby, C and Moore, M and Morris, HR and Morrison, KE and Mudanohwo, E and O'Sullivan, SS and Pearson, J and Perlmutter, JS and Petursson, H and Pollak, P and Post, B and Potter, S and Ravina, B and Revesz, T and Riess, O and Rivadeneira, F and Rizzu, P and Ryten, M and Sawcer, S and Schapira, A and Scheffer, H and Shaw, K and Shoulson, I and Sidransky, E and Smith, C and Spencer, CCA and Stefansson, H and Stockton, JD and Strange, A and Talbot, K and Tanner, CM and Tashakkori-Ghanbaria, A and Tison, F and Trabzuni, D and Traynor, BJ and Uitterlinden, AG and Velseboer, D and Vidailhet, M and Walker, R and van de Warrenburg, B and Wickremaratchi, M and Williams, N and Williams-Gray, CH and Winder-Rhodes, S and Stefansson, K and Martinez, M and Hardy, J and Heutink, P and Brice, A and Gasser, T and Singleton, AB and Wood, NW and Int Parkinson Dis Genomics Consort, and Wellcome Trust Case-Control Consor, (2011) Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies. LANCET , 377 (9766) 641 - 649. 10.1016/S0140-6736(10)62345-8.

Plagnol, V and Nalls, MA and Bras, JM and Hernandez, DG and Sharma, M and Sheerin, UM and Saad, M and Simon-Sanchez, J and Schulte, C and Lesage, S and Sveinbjornsdottir, S and Amouyel, P and Arepalli, S and Band, G and Barker, RA and Bellinguez, C and Ben-Shlomo, Y and Berendse, HW and Berg, D and Bhatia, K and de Bie, RMA and Biffi, A and Bloem, B and Bochdanovits, Z and Bonin, M and Brockmann, K and Brooks, J and Burn, DJ and Charlesworth, G and Chen, HL and Chinnery, PF and Chong, S and Clarke, CE and Cookson, MR and Cooper, JM and Corvol, JC and Counsell, C and Damier, P and Dartigues, JF and Deloukas, P and Deuschl, G and Dexter, DT and van Dijk, KD and Dillman, A and Durif, F and Durr, A and Edkins, S and Evans, JR and Foltynie, T and Freeman, C and Gao, JJ and Gardner, M and Gibbs, JR and Goate, A and Gray, E and Guerreiro, R and Gustafsson, O and Harris, C and Hellenthal, G and van Hilten, JJ and Hofman, A and Hollenbeck, A and Holton, J and Hu, M and Huang, XM and Huber, H and Hudson, G and Hunt, SE and Huttenlocher, J and Illig, T and Jonsson, PV and Langford, C and Lees, A and Lichtner, P and Limousin, P and Lopez, G and Lorenz, D and McNeill, A and Moorby, C and Moore, M and Morris, H and Morrison, KE and Mudanohwo, E and O'Sullivan, SS and Pearson, J and Pearson, R and Perlmutter, JS and Petursson, H and Pirinen, M and Pollak, P and Post, B and Potter, S and Ravina, B and Revesz, T and Riess, O and Rivadeneira, F and Rizzu, P and Ryten, M and Sawcer, S and Schapira, A and Scheffer, H and Shaw, K and Shoulson, I and Sidransky, E and de Silva, R and Smith, C and Spencer, CCA and Stefansson, H and Steinberg, S and Stockton, JD and Strange, A and Su, Z and Talbot, K and Tanner, CM and Tashakkori-Ghanbaria, A and Tison, F and Trabzuni, D and Traynor, BJ and Uitterlinden, AG and Vandrovcova, J and Velseboer, D and Vidailhet, M and Vukcevic, D and Walker, R and van de Warrenburg, B and Weale, ME and Wickremaratchi, M and Williams, N and Williams-Gray, CH and Winder-Rhodes, S and Stefansson, K and Martinez, M and Donnelly, P and Singleton, AB and Hardy, J and Heutink, P and Brice, A and Gasser, T and Wood, NW and WTCCC2, (2011) A Two-Stage Meta-Analysis Identifies Several New Loci for Parkinson's Disease. PLOS GENET , 7 (6) , Article e1002142. 10.1371/journal.pgen.1002142.
An open access publication

Proukakis, C and Moore, D and Labrum, R and Wood, NW and Houlden, H (2011) Detection of novel mutations and review of published data suggests that hereditary spastic paraplegia caused by spastin (SPAST) mutations is found more often in males. J NEUROL SCI , 306 (1-2) 62 - 65. 10.1016/j.jns.2011.03.043.

Sailer, A and Scholz, SW and Gibbs, JR and Johnson, JO and Wood, NW and Hernandez, D and Hardy, J and Federoff, H and Traynor, BJ and Singleton, AB and Houlden, H (2011) EXOME SEQUENCING AS A RAPID AND COST EFFICIENT DIAGNOSTIC METHOD IN NEUROGENETIC DISORDERS. In: EUROPEAN JOURNAL OF NEUROLOGY. (pp. 552 - 552). WILEY-BLACKWELL

Sawcer, S and Hellenthal, G and Pirinen, M and Spencer, CCA and Patsopoulos, NA and Moutsianas, L and Dilthey, A and Su, Z and Freeman, C and Hunt, SE and Edkins, S and Gray, E and Booth, DR and Potter, SC and Goris, A and Band, G and Oturai, AB and Strange, A and Saarela, J and Bellenguez, C and Fontaine, B and Gillman, M and Hemmer, B and Gwilliam, R and Zipp, F and Jayakumar, A and Martin, R and Leslie, S and Hawkins, S and Giannoulatou, E and D'alfonso, S and Blackburn, H and Boneschi, FM and Liddle, J and Harbo, HF and Perez, ML and Spurkland, A and Waller, MJ and Mycko, MP and Ricketts, M and Comabella, M and Hammond, N and Kockum, I and McCann, OT and Ban, M and Whittaker, P and Kemppinen, A and Weston, P and Hawkins, C and Widaa, S and Zajicek, J and Dronov, S and Robertson, N and Bumpstead, SJ and Barcellos, LF and Ravindrarajah, R and Abraham, R and Alfredsson, L and Ardlie, K and Aubin, C and Baker, A and Baker, K and Baranzini, SE and Bergamaschi, L and Bergamaschi, R and Bernstein, A and Berthele, A and Boggild, M and Bradfield, JP and Brassat, D and Broadley, SA and Buck, D and Butzkueven, H and Capra, R and Carroll, WM and Cavalla, P and Celius, EG and Cepok, S and Chiavacci, R and Clerget-Darpoux, F and Clysters, K and Comi, G and Cossburn, M and Cournu-Rebeix, I and Cox, MB and Cozen, W and Cree, BAC and Cross, AH and Cusi, D and Daly, MJ and Davis, E and de Bakker, PIW and Debouverie, M and D'hooghe, MB and Dixon, K and Dobosi, R and Dubois, B and Ellinghaus, D and Elovaara, I and Esposito, F and Fontenille, C and Foote, S and Franke, A and Galimberti, D and Ghezzi, A and Glessner, J and Gomez, R and Gout, O and Graham, C and Grant, SFA and Guerini, FR and Hakonarson, H and Hall, P and Hamsten, A and Hartung, HP and Heard, RN and Heath, S and Hobart, J and Hoshi, M and Infante-Duarte, C and Ingram, G and Ingram, W and Islam, T and Jagodic, M and Kabesch, M and Kermode, AG and Kilpatrick, TJ and Kim, C and Klopp, N and Koivisto, K and Larsson, M and Lathrop, M and Lechner-Scott, JS and Leone, MA and Leppa, V and Liljedahl, U and Bomfim, IL and Lincoln, RR and Link, J and Liu, JJ and Lorentzen, AR and Lupoli, S and Macciardi, F and Mack, T and Marriott, M and Martinelli, V and Mason, D and McCauley, JL and Mentch, F and Mero, IL and Mihalova, T and Montalban, X and Mottershead, J and Myhr, KM and Naldi, P and Ollier, W and Page, A and Palotie, A and Pelletier, J and Piccio, L and Pickersgill, T and Piehl, F and Pobywajlo, S and Quach, HL and Ramsay, PP and Reunanen, M and Reynolds, R and Rioux, J and Rodegher, M and Roesner, S and Rubio, JP and Ruckert, IM and Salvetti, M and Salvi, E and Santaniello, A and Schaefer, CA and Schreiber, S and Schulze, C and Scott, RJ and Sellebjerg, F and Selmaj, KW and Sexton, D and Shen, L and Simms-Acuna, B and Skidmore, S and Sleiman, PMA and Smestad, C and Sorensen, PS and Sondergaard, HB and Stankovich, J and Strange, RC and Sulonen, AM and Sundqvist, E and Syvanen, AC and Taddeo, F and Taylor, B and Blackwell, JM and Tienari, P and Bramon, E and Tourbah, A and Brown, MA and Tronczynska, E and Casas, JP and Tubridy, N and Corvin, A and Vickery, J and Jankowski, J and Villoslada, P and Markus, HS and Wang, K and Mathew, CG and Wason, J and Palmer, CNA and Wichmann, HE and Plomin, R and Willoughby, E and Rautanen, A and Winkelmann, J and Wittig, M and Trembath, RC and Yaouanq, J and Viswanathan, AC and Zhang, HT and Wood, NW and Zuvich, R and Deloukas, P and Langford, C and Duncanson, A and Oksenberg, JR and Pericak-Vance, MA and Haines, JL and Olsson, T and Hillert, J and Ivinson, AJ and De Jager, PL and Peltonen, L and Stewart, GJ and Hafler, DA and Hauser, SL and McVean, G and Donnelly, P and Compston, A and Int Multiple Sclerosis Genetics Co, and Wellcome Trust Case Control Consor, (2011) Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. NATURE , 476 (7359) 214 - 219. 10.1038/nature10251.

Sharma, S and Bandopadhyay, R and Lashley, T and Renton, AEM and Kingsbury, AE and Kumaran, R and Kallis, C and Vilarino-Guell, C and O'Sullivan, SS and Lees, AJ and Revesz, T and Wood, NW and Holton, JL (2011) LRRK2 expression in idiopathic and G2019S positive Parkinson's disease subjects: a morphological and quantitative study. NEUROPATH APPL NEURO , 37 (7) 777 - 790. 10.1111/j.1365-2990.2011.01187.x.

Spencer, CCA and Plagnol, V and Strange, A and Gardner, M and Paisan-Ruiz, C and Band, G and Barker, RA and Bellenguez, C and Bhatia, K and Blackburn, H and Blackwell, JM and Bramon, E and Brown, MA and Brown, MA and Burn, D and Casas, JP and Chinnery, PF and Clarke, CE and Corvin, A and Craddock, N and Deloukas, P and Edkins, S and Evans, J and Freeman, C and Gray, E and Hardy, J and Hudson, G and Hunt, S and Jankowski, J and Langford, C and Lees, AJ and Markus, HS and Mathew, CG and McCarthy, MI and Morrison, KE and Palmer, CNA and Pearson, JP and Peltonen, L and Pirinen, M and Plomin, R and Potter, S and Rautanen, A and Sawcer, SJ and Su, Z and Trembath, RC and Viswanathan, AC and Williams, NW and Morris, HR and Donnelly, P and Wood, NW and UK Parkinson's Dis Consortium, and Wellcome Trust Case Control Consor, (2011) Dissection of the genetics of Parkinson's disease identifies an additional association 5 ' of SNCA and multiple associated haplotypes at 17q21. HUM MOL GENET , 20 (2) 345 - 353. 10.1093/hmg/ddq469.

Yao, Z and Gandhi, S and Burchell, VS and Plun-Favreau, H and Wood, NW and Abramov, AY (2011) Cell metabolism affects selective vulnerability in PINK1-associated Parkinson's disease. J Cell Sci , 124 (Pt 24) 4194 - 4202. 10.1242/jcs.088260.
An open access publication

Zhou, KX and Bellenguez, C and Spencer, CCA and Bennett, AJ and Coleman, RL and Tavendale, R and Hawley, SA and Donnelly, LA and Schofield, C and Groves, CJ and Burch, L and Carr, F and Strange, A and Freeman, C and Blackwell, JM and Bramon, E and Brown, MA and Casas, JP and Corvin, A and Craddock, N and Deloukas, P and Dronov, S and Duncanson, A and Edkins, S and Gray, E and Hunt, S and Jankowski, J and Langford, C and Markus, HS and Mathew, CG and Plomin, R and Rautanen, A and Sawcer, SJ and Samani, NJ and Trembath, R and Viswanathan, AC and Wood, NW and Harries, LW and Hattersley, AT and Doney, ASF and Colhoun, H and Morris, AD and Sutherland, C and Hardie, DG and Peltonen, L and McCarthy, MI and Holman, RR and Palmer, CNA and Donnelly, P and Pearson, ER and GoDARTS UKPDS Diabet Pharmacogenet, and Wellcome Trust Case Control Consor, and MAGIC Investigators, (2011) Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes. NAT GENET , 43 (2) 117 - U57. 10.1038/ng.735.

2010

Alonso-Canovas, A and Katschnig, P and Tucci, A and Carecchio, M and Wood, NW and Edwards, M and Castrillo, JCM and Burke, D and Heales, S and Bhatia, KP (2010) Atypical Parkinsonism with Apraxia and Supranuclear Gaze Abnormalities in Type 1 Gaucher Disease. Expanding the Spectrum: Case Report and Literature Review. MOVEMENT DISORD , 25 (10) 1506 - 1509. 10.1002/mds.23109.

Bishop, MW and Chakraborty, S and Matthews, GAC and Dougalis, A and Wood, NW and Festenstein, R and Ungless, MA (2010) Hyperexcitable Substantia Nigra Dopamine Neurons in PINK1- and HtrA2/Omi-Deficient Mice. J NEUROPHYSIOL , 104 (6) 3009 - 3020. 10.1152/jn.00466.2010.

Burchell, VS and Gandhi, S and Deas, E and Wood, NW and Abramov, AY and Plun-Favreau, H (2010) Targeting mitochondrial dysfunction in neurodegenerative disease: Part II. EXPERT OPIN THER TAR , 14 (5) 497 - 511. 10.1517/14728221003730434.

Burchell, VS and Gandhi, S and Deas, E and Wood, NW and Abramov, AY and Plun-Favreau, H (2010) Targeting mitochondrial dysfunction in neurodegenerative disease: Part I. EXPERT OPIN THER TAR , 14 (4) 369 - 385. 10.1517/14728221003652489.

Gandhi, S and Wood, NW (2010) Genome-wide association studies: the key to unlocking neurodegeneration? NAT NEUROSCI , 13 (7) 789 - 794. 10.1038/nn.2584.

Heinzen, EL and Radtke, RA and Urban, TJ and Cavalleri, GL and Depondt, C and Need, AC and Walley, NM and Nicoletti, P and Ge, DL and Catarino, CB and Duncan, JS and Kasperaviciute, D and Tate, SK and Caboclo, LO and Sander, JW and Clayton, L and Linney, KN and Shianna, KV and Gumbs, CE and Smith, J and Cronin, KD and Maia, JM and Doherty, CP and Pandolfo, M and Leppert, D and Middleton, LT and Gibson, RA and Johnson, MR and Matthews, PM and Hosford, D and Kalviainen, R and Eriksson, K and Kantanen, AM and Dorn, T and Hansen, J and Kramer, G and Steinhoff, BJ and Wieser, HG and Zumsteg, D and Ortega, M and Wood, NW and Huxley-Jones, J and Mikati, M and Gallentine, WB and Husain, AM and Buckley, PG and Stallings, RL and Podgoreanu, MV and Delanty, N and Sisodiya, SM and Goldstein, DB (2010) Rare Deletions at 16p13.11 Predispose to a Diverse Spectrum of Sporadic Epilepsy Syndromes. The American Journal of Human Genetics , 86 (5) 707 - 718. 10.1016/j.ajhg.2010.03.018.
An open access publication

Kagi, G and Klein, C and Wood, NW and Schneider, SA and Pramstaller, PP and Tadic, V and Quinn, NP and van de Warrenburg, BPC and Bhatia, KP (2010) Nonmotor Symptoms in Parkin Gene-Related Parkinsonism. MOVEMENT DISORD , 25 (9) 1279 - 1284. 10.1002/mds.22897.

Kasperaviciute, D and Catarino, CB and Heinzen, EL and Depondt, C and Cavalleri, GL and Caboclo, LO and Tate, SK and Jamnadas-Khoda, J and Chinthapalli, K and Clayton, LMS and Shianna, KV and Radtke, RA and Mikati, MA and Gallentine, WB and Husain, AM and Alhusaini, S and Leppert, D and Middleton, LT and Gibson, RA and Johnson, MR and Matthews, PM and Hosford, D and Heuser, K and Amos, L and Ortega, M and Zumsteg, D and Wieser, HG and Steinhoff, BJ and Krarmer, G and Hansen, J and Dorn, T and Kantanen, AM and Gjerstad, L and Peuralinna, T and Hernandez, DG and Eriksson, KJ and Kalviainen, RK and Doherty, CP and Wood, NW and Pandolfo, M and Duncan, JS and Sander, JW and Delanty, N and Goldstein, DB and Sisodiya, SM (2010) Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study. BRAIN , 133 2136 - 2147. 10.1093/brain/awq130.

Mead, S and Gandhi, S and Carswell, C and Ayling, H and Beck, J and Caine, D and Gallujipali, D and Hyare, H and Joiner, S and Lees, AJ and Linehan, J and Revesz, T and Sandberg, M and Wadsworth, JDF and Warren, JD and Wood, NW and Holton, JL and Collinge, J (2010) Novel Truncation Mutation of PRNP Causes Chronic Diarrhoea, Sensory Neuropathy and Autonomic Failure Associated with Prion Protein Deposition in the Cerebral Blood Vessels and Small Bowel. PRION , 4 (3) 201 - 202.

Novak, MJU and Tabrizi, SJ (2010) Huntington's disease. In: UNSPECIFIED (? - ?). B M J PUBLISHING GROUP

Pavese, N and Moore, RY and Scherfler, C and Khan, NL and Hotton, G and Quinn, NP and Bhatia, KP and Wood, NW and Brooks, DJ and Lees, AJ and Piccini, P (2010) In vivo assessment of brain monoamine systems in parkin gene carriers: A PET study. EXP NEUROL , 222 (1) 120 - 124. 10.1016/j.expneurol.2009.12.021.

Plun-Favreau, H and Lewis, PA and Hardy, J and Martins, LM and Wood, NW (2010) Cancer and Neurodegeneration: Between the Devil and the Deep Blue Sea. PLOS GENET , 6 (12) , Article e1001257. 10.1371/journal.pgen.1001257.
An open access publication

Rajakulendran, S and Graves, TD and Labrum, RW and Kotzadimitriou, D and Eunson, L and Davis, MB and Davies, R and Wood, NW and Kullmann, DM and Hanna, MG and Schorge, S (2010) Genetic and functional characterisation of the P/Q calcium channel in episodic ataxia with epilepsy. J PHYSIOL-LONDON , 588 (11) 1905 - 1913. 10.1113/jphysiol.2009.186437.

Sebastian, CL and Roiser, JP and Tan, GCY and Viding, E and Wood, NW and Blakemore, SJ (2010) Effects of age and MAOA genotype on the neural processing of social rejection. GENES BRAIN BEHAV , 9 (6) 628 - 637. 10.1111/j.1601-183X.2010.00596.x.

Tan, GCY and Doke, TF and Ashburner, J and Wood, NW and Frackowiak, RSJ (2010) Normal variation in fronto-occipital circuitry and cerebellar structure with an autism-associated polymorphism of CNTNAP2. NEUROIMAGE , 53 (3) 1030 - 1042. 10.1016/j.neuroimage.2010.02.018.

Tucci, A and Nalls, MA and Houlden, H and Revesz, T and Singleton, AB and Wood, NW and Hardy, J and Paisan-Ruiz, C (2010) Genetic variability at the PARK16 locus. EUR J HUM GENET , 18 (12) 1356 - 1359. 10.1038/ejhg.2010.125.

2009

da Costa, CA and Sunyach, C and Giaime, E and West, A and Corti, O and Brice, A and Safe, S and Abou-Sleiman, PM and Wood, NW and Takahashi, H and Goldberg, MS and Shen, J and Checler, F (2009) Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease. NAT CELL BIOL , 11 (11) 1370 - U255. 10.1038/ncb1981.

Deas, E and Plun-Favreau, H and Wood, NW (2009) PINK1 function in health and disease. EMBO MOL MED , 1 (3) 152 - 165. 10.1002/emmm.200900024.
An open access publication

Gandhi, S and Wood-Kaczmar, A and Yao, Z and Plun-Favreau, H and Deas, E and Klupsch, K and Downward, J and Latchman, DS and Tabrizi, SJ and Wood, NW and Duchen, MR and Abramov, AY (2009) PINK1-Associated Parkinson's Disease Is Caused by Neuronal Vulnerability to Calcium-induced Cell Death. MOL CELL , 33 (5) 627 - 638. 10.1016/j.molcel.2009.02.013.
An open access publication

Healy, DG and Bressman, S and Dickson, J and Silveira-Moriyama, L and Schneider, SA and Sullivan, SSO and Massey, L and Bhatia, KP and Shaw, K and Bomanji, J and Wood, NW and Lees, AJ (2009) Evidence for Pre and Postsynaptic Nigrostriatal Dysfunction in the Fragile X Tremor-Ataxia Syndrome. MOVEMENT DISORD , 24 (8) 1245 - 1247. 10.1002/mds.22267.

Healy, DG and Sullivan, SO and Bonifati, V and Durr, A and Bressman, S and Brice, A and Aasly, J and Zabetian, C and Ferreira, J and Tolosa, E and Klein, C and Lang, A and Wszolek, Z and Lynch, T and Bhatia, K and Gasser, T and Lees, AJ and Wood, NW (2009) LRRK2 ASSOCIATED PARKINSON'S DISEASE: CLINICAL FACTORS BASED ON WORLDWIDE EXPERIENCE. In: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. (pp. 105 - 106). B M J PUBLISHING GROUP

Kumaran, R and Vandrovcova, J and Luk, C and Sharma, S and Renton, A and Wood, NW and Hardy, JA and Lees, AJ and Bandopadhyay, R (2009) Differential DJ-1 gene expression in Parkinson's disease. NEUROBIOL DIS , 36 (2) 393 - 400. 10.1016/j.nbd.2009.08.011.

Lynch, JM and Tate, SK and Kinirons, P and Weale, ME and Cavalleri, GL and Depondt, C and Murphy, K and O'Rourke, D and Doherty, CP and Shianna, KV and Wood, NW and Sander, JW and Delanty, N and Goldstein, DB and Sisodiya, SM (2009) No major role of common SV2A variation for predisposition or levetiracetam response in epilepsy. EPILEPSY RES , 83 (1) 44 - 51. 10.1016/j.eplepsyres.2008.09.003.

Michell, AW and Laura, M and Blake, J and Lunn, MP and Cox, A and Gibbons, VS and Davis, MB and Wood, NW and Manji, H and Houlden, H and Murray, NMF and Reilly, MM (2009) GJB1 gene mutations in suspected inflammatory demyelinating neuropathies not responding to treatment. J NEUROL NEUROSUR PS , 80 (6) 699 - 700. 10.1136/jnnp.2008.150557.

Moisoi, N and Klupsch, K and Fedele, V and East, P and Sharma, S and Renton, A and Plun-Favreau, H and Edwards, RE and Teismann, P and Esposti, MD and Morrison, AD and Wood, NW and Downward, J and Martins, LM (2009) Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response. CELL DEATH DIFFER , 16 (3) 449 - 464. 10.1038/cdd.2008.166.

Neumann, J and Bras, J and Deas, E and O'Sullivan, SS and Parkkinen, L and Lachmann, RH and Li, A and Holton, J and Guerreiro, R and Paudel, R and Segarane, B and Singleton, A and Lees, A and Hardy, J and Houlden, H and Revesz, T and Wood, NW (2009) Glucocerebrosidase mutations in clinical and pathologically proven Parkinson's disease. BRAIN , 132 1783 - 1794. 10.1093/brain/awp044.
An open access publication

Neumann, J and Parkkinen, L and Bras, J and O'sullivan, SS and Deas, E and Lachmann, H and Li, A and Holton, L and Guerreiro, R and Paudel, R and Segarane, B and Singleton, A and Lees, A and Hardy, J and Houlden, H and Revesz, T and Wood, NW (2009) Glucocerebrosidase mutations in clinical and pathologically proven Parkinson's disease. In: NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. (pp. 3 - 3). BLACKWELL PUBLISHING

Paisan-Ruiz, C and Bhatia, KP and Li, A and Hernandez, D and Davis, M and Wood, NW and Hardy, J and Houlden, H and Singleton, A and Schneider, SA (2009) Characterization of PLA2G6 as a Locus for Dystonia-Parkinsonism. ANN NEUROL , 65 (1) 19 - 23. 10.1002/ana.21415.

Pavese, N and Khan, NL and Scherfler, C and Cohen, L and Brooks, DJ and Wood, NW and Bhatia, KP and Quinn, NP and Lees, AJ and Piccini, P (2009) Nigrostriatal Dysfunction in Homozygous and Heterozygous Parkin Gene Carriers: An F-18-Dopa PET Progression Study. MOVEMENT DISORD , 24 (15) 2260 - 2266. 10.1002/mds.22817.

Proukakis, C and Moore, D and Labrum, R and Wood, NW and Houlden, H (2009) A clinical and genetic study of hereditary spastic paraplegia caused by SPAST/SPG4 mutations, including 12 new mutations. In: EUROPEAN JOURNAL OF NEUROLOGY. (pp. 296 - 296). WILEY-BLACKWELL PUBLISHING, INC

Roiser, JP and de Martino, B and Tan, GCY and Kumaran, D and Seymour, B and Wood, NW and Dolan, RJ (2009) A Genetically Mediated Bias in Decision Making Driven by Failure of Amygdala Control. J NEUROSCI , 29 (18) 5985 - 5991. 10.1523/JNEUROSCI.0407-09.2009.
An open access publication

Segarane, B and Li, A and Paudel, R and Scholz, S and Neumann, J and Lees, A and Revesz, T and Hardy, J and Mathias, CJ and Wood, NW and Holton, J and Houlden, H (2009) GLUCOCEREBROSIDASE MUTATIONS IN 108 NEUROPATHOLOGICALLY CONFIRMED CASES OF MULTIPLE SYSTEM ATROPHY. NEUROLOGY , 72 (13) 1185 - 1186. 10.1212/01.wnl.0000345356.40399.eb.
An open access publication

Sharma, S and Bandopadhyay, R and Kingsbury, AE and Lashley, TC and Lees, AJ and Revesz, T and Wood, NW and Holton, JL (2009) LRRK2 mRNA and protein expression in Parkinson's disease cases with LRRK2 G2019S mutation. In: NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. (pp. 27 - 28). BLACKWELL PUBLISHING

Simon-Sanchez, J and Schulte, C and Bras, JM and Sharma, M and Gibbs, JR and Berg, D and Paisan-Ruiz, C and Lichtner, P and Scholz, SW and Hernandez, DG and Kruger, R and Federoff, M and Klein, C and Goate, A and Perlmutter, J and Bonin, M and Nalls, MA and Illig, T and Gieger, C and Houlden, H and Steffens, M and Okun, MS and Racette, BA and Cookson, MR and Foote, KD and Fernandez, HH and Traynor, BJ and Schreiber, S and Arepalli, S and Zonozi, R and Gwinn, K and van der Brug, M and Lopez, G and Chanock, SJ and Schatzkin, A and Park, Y and Hollenbeck, A and Gao, JJ and Huang, XM and Wood, NW and Lorenz, D and Deuschl, G and Chen, HL and Riess, O and Hardy, JA and Singleton, AB and Gasser, T (2009) Genome-wide association study reveals genetic risk underlying Parkinson's disease. NAT GENET , 41 (12) 1308 - U68. 10.1038/ng.487.

Sleiman, PMA and Healy, DG and Muqit, MMK and Yang, YX and Van der Brug, M and Holton, JL and Revesz, T and Quinn, NP and Bhatia, K and Diss, JKJ and Lees, AJ and Cookson, MR and Latchman, DS and Wood, NW (2009) Characterisation of a novel NR4A2 mutation in Parkinson's disease brain. NEUROSCI LETT , 457 (2) 75 - 79. 10.1016/j.neulet.2009.03.021.

Trender-Gerhard, I and Sweeney, MG and Schwingenschuh, P and Mir, P and Edwards, MJ and Gerhard, A and Polke, JM and Hanna, MG and Davis, MB and Wood, NW and Bhatia, KP (2009) Autosomal-dominant GTPCH1-deficient DRD: clinical characteristics and long-term outcome of 34 patients. J NEUROL NEUROSUR PS , 80 (8) 839 - 845. 10.1136/jnnp.2008.155861.

Vandrovcova, J and Pittman, AM and Malzer, E and Abou-Sleiman, PM and Lees, AJ and Wood, NW and de Silva, R (2009) Association of MAPT haplotype-tagging SNPs with sporadic Parkinson's disease. NEUROBIOL AGING , 30 (9) 1477 - 1482. 10.1016/j.neurobiolaging.2007.11.019.

Wood, N (2009) Cerebellar ataxias and related conditions. In: Clarke, C and Howard, R and Rossor, M and Shorvon, S, (eds.) Neurology: a Queen Square textbook. (629 - 643). Wiley-Blackwell: Chichester.

Wood-Kaczmar, A and Gandhi, S and Yao, Z and Abramov, AY and Miljan, EA and Keen, G and Stanyer, L and Hargreaves, I and Klupsch, K and Downward, J and Mansfield, L and Jat, P and Taylor, J and Heales, S and Duchen, MR and Latchman, D and Tabrizi, SJ and Wood, NW (2009) PINK1 is necessary for long term survival and mitochondrial function in primary human dopaminergic neurons. In: JOURNAL OF NEUROCHEMISTRY. (pp. 301 - 302). WILEY-BLACKWELL PUBLISHING, INC

Yang, YX and Wood, NW and Latchman, DS (2009) Molecular basis of Parkinson's disease. NEUROREPORT , 20 (2) 150 - 156. 10.1097/WNR.0b013e32831c50df.

Yao, Z and Bandopadhyay, R and Muqit, MMK and Holton, JL and Wood, NW (2009) Putative LRRK2 (PARK8) substrates: ERM proteins are present in Lewy bodies and are up-regulated in Parkinson's disease brains. In: NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. (pp. 28 - 28). BLACKWELL PUBLISHING

Yao, Z and Klupsh, K and Hargreaves, I and Downward, J and Heales, S and Revesz, T and Holton, J and Wood, NW (2009) Characterisation of PINK1 knockout mice. In: JOURNAL OF NEUROCHEMISTRY. (pp. 300 - 300). WILEY-BLACKWELL PUBLISHING, INC

Yao, Z and Wood, NW (2009) Cell Death Pathways in Parkinson's Disease: Role of Mitochondria. ANTIOXID REDOX SIGN , 11 (9) 2135 - 2149. 10.1089/ars.2009.2624.

2008

Gilman, S and Wenning, GK and Low, PA and Brooks, DJ and Mathias, CJ and Trojanowski, JQ and Wood, NW and Colosimo, C and Duerr, A and Fowler, CJ and Kaufmann, H and Klockgether, T and Lees, A and Poewe, W and Quinn, N and Revesz, T and Robertson, D and Sandroni, P and Seppi, K and Vidailhet, M (2008) Second consensus statement on the diagnosis of multiple system atrophy. NEUROLOGY , 71 (9) 670 - 676.

Healy, DG and Falchi, M and O'Sullivan, SS and Bonifati, V and Durr, A and Bressman, S and Brice, A and Aasly, J and Zabetian, CP and Goldwurm, S and Ferreira, JJ and Tolosa, E and Kay, DM and Klein, C and Williams, DR and Marras, C and Lang, AE and KWszolek, Z and Berciano, J and Schapira, AHV and Lynch, T and Bhatia, KP and Gasser, T and Lees, AJ and Wood, NW and Int LRRK2 Consortium, (2008) Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study. LANCET NEUROL , 7 (7) 583 - 590. 10.1016/S1474-4422(08)70117-0.
An open access publication

Healy, DG and Wood, NW and Schapira, AH (2008) Test for LRRK2 mutations in patients with Parkinson's disease. Pract Neurol , 8 (6) 381 - 385. 10.1136/jnnp.2008.162420.

Holton, JL and Schneider, SA and Ganesharajah, T and Gandhi, S and Strand, C and Shashidharan, P and Barreto, J and Wood, NW and Lees, AJ and Bhatia, KP and Revesz, T (2008) Neuropathology of primary adult-onset dystonia. NEUROLOGY , 70 (9) 695 - 699.

Holton, JL and Schneider, SA and Ganesharajah, T and Gandhi, S and Strand, C and Shashidharan, P and Barreto, J and Wood, NW and Lees, AL and Bhatia, KP and Revesz, T (2008) Neuropathology of primary adult onset non-DYT1 dystonia. In: JOURNAL OF NEUROLOGY. (pp. 98 - 98). DR DIETRICH STEINKOPFF VERLAG

Houlden, H and Johnson, J and Gardner-Thorpe, C and Lashley, T and Hernandez, D and Singleton, AB and Holton, J and Revesz, T and Davis, MB and Giunti, P and Wood, NW (2008) Tau tubulin kinase 2, implicated by tau phosphorylation, contains mutations that segregate with spinocerebellar ataxia type II. In: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. (pp. 344 - 344). B M J PUBLISHING GROUP

Houlden, H and Laura, M and Wavrant-De Vrieze, F and Blake, J and Wood, N and Reilly, MM (2008) Mutations in the HSP27 (HSPB1) gene cause dominant, recessive, and sporadic distal HMN/CMT type 2. NEUROLOGY , 71 (21) 1660 - 1668. 10.1212/01.wnl.0000319696.14225.67.

Johnson, J and Wood, N and Giunti, P and Houlden, H (2008) Clinical and genetic analysis of spinocerebellar ataxia type 11. CEREBELLUM , 7 (2) 159 - 164. 10.1007/s12311-008-0022-3.

Kagi, G and Klein, C and Wood, NW and Schneider, SA and Pramstaller, PP and Tadic, V and Quinn, NP and van de Warrenburg, BP and Bhatia, KP (2008) Non-motor symptoms in parkin gene-related parkinsonism. In: MOVEMENT DISORDERS. (pp. S352 - S352). WILEY-LISS

Lashley, T and Holton, JL and Gray, E and Kirkham, K and O'Sullivan, SS and Hilbig, A and Wood, NW and Lees, AJ and Revesz, T (2008) Cortical alpha-synuclein load is associated with amyloid-beta plaque burden in a subset of Parkinson's disease patients. ACTA NEUROPATHOL , 115 (4) 417 - 425. 10.1007/s00401-007-0336-0.

Lashley, T and Revesz, T and Plant, G and Bandopadhyay, R and Lees, AJ and Frangione, B and Wood, NW and de Silva, R and Ghiso, J and Rostagno, A and Holton, JL (2008) Expression of BRI2 mRNA and protein in normal human brain and familial British dementia: its relevance to the pathogenesis of disease. NEUROPATH APPL NEURO , 34 (5) 492 - 505. 10.1111/j.1365-2990.2008.00935.x.
An open access publication

Mortiboys, H and Thomas, KJ and Koopman, WJH and Klaffke, S and Abou-Sleiman, P and Olpin, S and Wood, NW and Willems, PHGM and Smeitink, JAM and Cookson, MR and Bandmann, O (2008) Mitochondrial Function and Morphology Are Impaired in parkin-Mutant Fibroblasts. ANN NEUROL , 64 (5) 555 - 565. 10.1002/ana.21492.

Muqit, MMK and Larner, AJ and Sweeney, MG and Sewry, C and Stinton, VJ and Davis, MB and Healy, DG and Payne, SJ and Chotai, K and Wood, NW and Lane, RJM (2008) Multiple mitochondrial DNA deletions in monozygotic twins with OPMD. J NEUROL NEUROSUR PS , 79 (1) 68 - 71. 10.1136/jnnp.2006.112250.

Paisan-Ruiz, C and Nath, P and Wood, NW and Singleton, A and Houlden, H (2008) Clinical heterogeneity and genotype-phenotype correlations in hereditary spastic paraplegia because of Spatacsin mutations (SPG11). EUR J NEUROL , 15 (10) 1065 - 1070. 10.1111/j.1468-1331.2008.02247.x.

Pavese, N and Khan, NL and Wood, NW and Quinn, NP and Lees, AJ and Brooks, DJ and Piccini, P (2008) Nigrostriatal dysfunction in parkin linked parkinsonism and asymptomatic heterozygous carriers: A progressive study with 18-dopa pet. In: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. (pp. 341 - 341). B M J PUBLISHING GROUP

Pittman, A and de Silva, R and Lees, AJ and Wood, NW (2008) Genetics of progressive supranuclear palsy. In: UNSPECIFIED (475 - 485).

Plun-Favreau, H and Gandhi, S and Wood-Kaczmar, A and Deas, E and Yao, Z and Wood, NW (2008) What Have PINK1 and HtrA2 Genes Told Us about the Role of Mitochondria in Parkinson's Disease? MITOCHONDRIA AND OXIDATIVE STRESS IN NEURODEGENERATIVE DISORDERS , 1147 30 - 36. 10.1196/annals.1427.032.

Schneider, SA and Talelli, P and Cheeran, BJ and Khan, NL and Wood, NW and Rothwell, JC and Bhatia, KP (2008) Motor Cortical Physiology in Patients and Asymptomatic Carriers of Parkin Gene Mutations. MOVEMENT DISORD , 23 (13) 1812 - 1819. 10.1002/mds.22025.

Silveira-Moriyama, L and Guedes, LC and Kingsbury, A and Ayling, H and Shaw, K and Barbosa, ER and Bonifati, V and Quinn, NP and Abou-Sleiman, P and Wood, NW and Petrie, A and Sampaio, C and Ferreira, JJ and Holton, J and Revesz, T and Lees, AJ (2008) Hyposmia in G2019S LRRK2-related parkinsonism - Clinical and pathologic data. NEUROLOGY , 71 (13) 1021 - 1026.

Trender-Gerhard, I and Sweeney, MG and Schwingenschuh, P and Mir, P and Edwards, MJ and Gerhard, A and Davis, MB and Wood, NW and Bhatia, KP (2008) Autosomal-dominant GTPCH1-deficient DRD: clinical characteristics and long-term outcome in 34 patients. In: EUROPEAN JOURNAL OF NEUROLOGY. (pp. 17 - 17). BLACKWELL PUBLISHING

Wood-Kaczmar, A and Gandhi, S and Yao, Z and Abramov, ASY and Miljan, EA and Keen, G and Stanyer, L and Hargreaves, I and Klupsch, K and Deas, E and Downward, J and Mansfield, L and Jat, P and Taylor, J and Heales, S and Duchen, MR and Latchman, D and Tabrizi, SJ and Wood, NW (2008) PINK1 Is Necessary for Long Term Survival and Mitochondrial Function in Human Dopaminergic Neurons. PLOS ONE , 3 (6) , Article e2455. 10.1371/journal.pone.0002455.
An open access publication. A version is also available from UCL Discovery.

2007

Cavalleri, GL and Walley, NM and Soranzo, N and Mulley, J and Doherty, CP and Kapoor, A and Depondt, C and Lynch, JM and Scheffer, IE and Heils, A and Gehrmann, A and Kinirons, P and Gandhi, S and Satishchandra, P and Wood, NW and Anand, A and Sander, T and Berkovic, SF and Delanty, N and Goldstein, DB and Sisodiya, SM (2007) A multicenter study of BRD2 as a risk factor for juvenile myoclonic epilepsy. EPILEPSIA , 48 (4) 706 - 712. 10.1111/j.1528-1167.2007.00977.x.

Cavalleri, GL and Weale, ME and Shianna, KV and Singh, R and Lynch, JM and Grinton, B and Szoeke, C and Murphy, K and Kinirons, P and O'Rourke, D and Ge, D and Depondt, C and Claeys, KG and Pandolfo, M and Gumbs, C and Walley, N and McNamara, J and Mulley, JC and Linney, KN and Sheffield, LJ and Radtke, RA and Tate, SK and Chissoe, SL and Gibson, RA and Hosford, D and Stanton, A and Graves, TD and Hanna, MG and Eriksson, K and Kantanen, AM and Kalviainen, R and O'Brien, TJ and Sander, JW and Duncan, JS and Scheffer, IE and Berkovic, SF and Wood, NW and Doherty, CP and Delanty, N and Sisodiya, SM and Goldstein, DB (2007) Multicentre search for genetic susceptibility loci in sporadic epilepsy syndrome and seizure types: a case-control study. LANCET NEUROL , 6 (11) 970 - 980. 10.1016/Sl474-4422(07)70247-8.

Giunti, P and Wood, N (2007) The inherited ataxias. ACNR , 7 (5) 18 - 21.

Heinzen, EL and Yoon, W and Tate, SK and Sen, A and Wood, NW and Sisodiya, SM and Goldstein, DB (2007) Nova2 interacts with a cis-acting polymorphism to influence the proportions of drug-responsive splice variants of SCN1A. AM J HUM GENET , 80 (5) 876 - 883. 10.1086/516650.

Heinzen, EL and Yoon, W and Weale, ME and Sen, A and Wood, NW and Burke, JR and Welsh-Bohmer, KA and Hulette, CM and Sisodiya, SM and Goldstein, DB (2007) Alternative ion channel splicing in mesial temporal lobe epilepsy and Alzheimer's disease. GENOME BIOL , 8 (3) , Article R32. 10.1186/gb-2007-8-3-r32.

Houlden, H and Johnson, J and Gardner-Thorpe, C and Lashley, T and Hernandez, D and Worth, P and Singleton, AB and Hilton, DA and Holton, J and Revesz, T and Davis, MB and Giunti, P and Wood, NW (2007) Mutations in TTBK2, encoding a kinase implicated in tau phosphorylation, segregate with spinocerebellar ataxia type 11. NAT GENET , 39 (12) 1434 - 1436. 10.1038/ng.2007.43.

Kasperaviciute, D and Weale, ME and Shianna, KV and Banks, GT and Simpson, CL and Hansen, VK and Turner, MR and Shaw, CE and Al-Chalabi, A and Pall, HS and Goodall, EF and Morrison, KE and Orrell, RW and Beck, M and Jablonka, S and Sendtner, M and Brockington, A and Ince, PG and Hartley, J and Nixon, H and Shaw, PJ and Schiavo, G and Wood, NW and Goldstein, DB and Fisher, EMC (2007) Large-scale pathways-based association study in amyotrophic lateral sclerosis. BRAIN , 130 2292 - 2301. 10.1093/brain/awm055.

Khan, NL and Bhatt, M and Brooks, DJ and Korlipara, P and Schapira, A and Piccini, P and Wood, NW and Bhatia, K (2007) An Indian kindred with reversible dystonia and parkinsonism. In: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. (pp. 210 - 210). B M J PUBLISHING GROUP

Limaye, N and Revencu, N and Van Regemorter, N and Garzon, M and Bonduelle, M and Chung, W and Daras, MD and Fahey, MC and Garrett, C and Gillerot, Y and Gillessen-Kaesbach, G and Giménez-Arnau, A and Guzzetta, F and Battaglia, D and Heimdal, K and Lissens, W and Taub, E and Van Maldergem, L and Van Paesschen, W and Wieczorek, D and Wood, NW and Boon, L and Vikkula, M (2007) Novel human pathological mutations. Gene symbol: KRIT1. Disease: cerebral cavernous malformation. Hum Genet , 122 (5) 552 - ?.

McKenzie, M and Liolitsa, D and Akinshina, N and Campanella, M and Sisodiya, S and Hargreaves, I and Nirmalananthan, N and Sweeney, MG and Abou-Sleiman, PM and Wood, NW and Hanna, MG and Duchen, MR (2007) Mitochondrial ND5 gene variation associated with encephalomyopathy and mitochondrial ATP consumption. J BIOL CHEM , 282 (51) 36845 - 36852. 10.1074/jbc.M704158200.
An open access publication

Plun-Favreau, H and Klupsch, K and Moisoi, N and Gandhi, S and Kjaer, S and Frith, D and Harvey, K and Deas, E and Harvey, RJ and McDonald, N and Wood, NW and Martins, LM and Downward, J (2007) The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1. NAT CELL BIOL , 9 (11) 1243 - U63. 10.1038/ncb1644.

Sisodiya, S and Cross, JH and Blümcke, I and Chadwick, D and Craig, J and Crino, PB and Debenham, P and Delanty, N and Elmslie, F and Gardiner, M and Golden, J and Goldstein, D and Greenberg, DA and Guerrini, R and Hanna, M and Harris, J and Harrison, P and Johnson, MR and Kirov, G and Kullman, DM and Makoff, A and Marini, C and Nabbout, R and Nashef, L and Noebels, JL and Ottman, R and Pirmohamed, M and Pitkänen, A and Scheffer, I and Shorvon, S and Sills, G and Wood, N and Zuberi, S (2007) Genetics of epilepsy: epilepsy research foundation workshop report. Epileptic Disord , 9 (2) 194 - 236. 10.1684/epd.2007.0107.

van de Leemput, J and Chandran, J and Knight, MA and Holtzclaw, LA and Scholz, S and Cookson, MR and Houlden, H and Gwinn-Hardy, K and Fung, HC and Lin, X and Hernandez, D and Simon-Sanchez, J and Wood, NW and Giunti, P and Rafferty, I and Hardy, J and Storey, E and Gardner, RJM and Forrest, SM and Fisher, EMC and Russell, JT and Cai, H and Singleton, AB (2007) Deletion at ITPR1 underlies ataxia in mice and spinocerebellar ataxia 15 in humans. PLOS GENET , 3 (6) , Article e108. 10.1371/journal.pgen.0030108.
An open access publication

van de Warrenburg, BPC and Giunti, P and Schneider, SA and Quinn, NP and Wood, NW and Bhatia, KP (2007) The syndrome of (predominantly cervical) dystonia and cerebellar ataxia: new cases indicate a distinct but heterogeneous entity. J NEUROL NEUROSUR PS , 78 (7) 774 - 775. 10.1136/jnnp.2006.105841.

2006

Abou-Sleiman, PM and Hanna, MG and Wood, NW (2006) Genetic association studies of complex neurological diseases. J NEUROL NEUROSUR PS , 77 (12) 1302 - 1304. 10.1136/jnnp.2005.082024.

Abou-Sleiman, PM and Muqit, MMK and McDonald, NQ and Yang, YX and Gandhi, S and Healy, DG and Harvey, K and Harvey, RJ and Deas, E and Hatia, K and Quinn, N and Lees, A and Latchman, DS and Wood, NW (2006) A heterozygous effect for PINK1 mutations in Parkinson's disease? ANN NEUROL , 60 (4) 414 - 419. 10.1002/ana.20960.

Abou-Sleiman, PM and Muqit, MMK and Wood, NW (2006) Expanding insights of mitochondrial dysfunction in Parkinson's disease. NAT REV NEUROSCI , 7 (3) 207 - 219. 10.1038/nrn1868.

Gandhi, S and Muqit, MMK and Abou-Sleiman, PM and Stanyer, L and Hargreaves, I and Heales, S and Ganguly, M and Latchman, DS and Holton, J and Wood, NW and Revesz, T (2006) PINK1: a novel mitochondrial protein in Parkinson's disease. In: NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. (pp. 221 - 222). BLACKWELL PUBLISHING

Gandhi, S and Muqit, MMK and Stanyer, L and Healy, DG and Abou-Sleiman, PM and Hargreaves, I and Heales, S and Ganguly, M and Parsons, L and Lees, AJ and Latchman, DS and Holton, JL and Wood, NW and Revesz, T (2006) PINK1 protein in normal human brain and Parkinson's disease. BRAIN , 129 1720 - 1731. 10.1093/brain/awl114.

Graves, TD and Schorge, S and Davies, RA and Wood, NW and Kullmann, DM and Hanna, MG (2006) The role of the brain P/Q-type calcium channel in human epilepsy. EUR J NEUROL , 13 313 - 313.

Healy, DG and Abou-Sleiman, PM and Ahmadi, KR and Gandhi, S and Muqit, MM and Bhatia, KP and Quinn, NP and Lees, AJ and Holton, JL and Revesz, T and Wood, NW (2006) NR4A2 genetic variation in sporadic Parkinson's disease: A genewide approach. MOVEMENT DISORD , 21 (11) 1960 - 1963. 10.1002/mds.21018.

Healy, DG and Abou-Sleiman, PM and Casas, JP and Ahmadi, KR and Lynch, T and Gandhi, S and Muqit, MMK and Foltynie, T and Barker, R and Bhatia, KP and Quinn, NP and Lees, AJ and Gibson, JM and Holton, JL and Revesz, T and Goldstein, DB and Wood, NW (2006) UCHL-1 is not a Parkinson's disease susceptibility gene. ANN NEUROL , 59 (4) 627 - 633. 10.1002/ana.20757.

Hu, MTM and Scherfle, C and Khan, NL and Hajnal, JV and Lees, AJ and Quinn, N and Wood, NW and Brooks, DJ (2006) Nigral degeneration and striatal dopaminergic dysfunction in idiopathic and Parkin-linked Parkinson's disease. MOVEMENT DISORD , 21 (3) 299 - 305. 10.1002/mds.20702.

Kinirons, P and Cavalleri, GL and Shahwan, A and Wood, NW and Goldstein, DB and Sisodiya, SM and Delanty, N and Doherty, CP (2006) Examining the role of common genetic variation in the gamma 2 subunit of the GABA(A) receptor in epilepsy using tagging SNPs. EPILEPSY RES , 70 (2-3) 229 - 238. 10.1016/j.eplepsyres.2005.05.009.

Kinirons, P and Cavalleri, GL and Shahwan, A and Wood, NW and Goldstein, DB and Sisodiya, SM and Delanty, N and Doherty, CP (2006) Examining the role of common genetic variation in the gamma2 subunit of the GABA(A) receptor in epilepsy using tagging SNPs. Epilepsy Res , 70 (2-3) 229 - 238. 10.1016/j.eplepsyres.2006.05.009.

Kinirons, P and Cavalleri, GL and Singh, R and Shahwan, A and Acheson, JF and Wood, NW and Goldstein, DB and Sisodiya, SM and Doherty, CP and Delanty, N (2006) A pharmacogenetic exploration of vigabatrin-induced visual field constriction. EPILEPSY RES , 70 (2-3) 144 - 152. 10.1016/j.eplepsyres.2006.03.012.

Muqit, MMK and Abou-Sleiman, PM and Saurin, AT and Harvey, K and Gandhi, S and Deas, E and Eaton, S and Smith, MDP and Venner, K and Matilla, A and Healy, DG and Gilks, WP and Lees, AJ and Holton, J and Revesz, T and Parker, PJ and Harvey, RJ and Wood, NW and Latchman, DS (2006) Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress. J NEUROCHEM , 98 (1) 156 - 169. 10.1111/j.1471-4159.2006.03845.x.

Muqit, MMK and Gandhi, S and Wood, NW (2006) Mitochondria in Parkinson disease - Back in fashion with a little help from genetics. ARCH NEUROL-CHICAGO , 63 (5) 649 - 654.

Ozawa, T and Healy, DG and Abou-Sleiman, PM and Ahmadi, KR and Quinn, N and Lees, AJ and Shaw, K and Wullner, U and Berciano, J and Moller, JC and Kamm, C and Burk, K and Josephs, KA and Barone, P and Tolosa, E and Goldstein, DB and Wenning, G and Geser, F and Holton, JL and Gasser, T and Revesz, T and Wood, NW and European MSA Study Group, (2006) The alpha-synuclein gene in multiple system atrophy. J NEUROL NEUROSUR PS , 77 (4) 464 - 467. 10.1136/jnnp.2005.073528.

Schmitt, I and Wullner, U and Healy, DG and Wood, NW and Kolsch, H and Henn, R (2006) The ADH1C stop mutation in multiple system atrophy patients and healthy probands in the United Kingdom and Germany. MOVEMENT DISORD , 21 (11) 2034 - 2034. 10.1002/mds.21082.

Schneider, SA and Mohire, MD and Trender-Gerhard, I and Asmus, F and Sweeney, M and Davis, M and Gasser, T and Wood, NW and Bhatia, KP (2006) Familial dopa-responsive cervical dystonia. NEUROLOGY , 66 (4) 599 - 601.

Schneider, SA and van de Warrenburg, BPC and Hughes, TD and Davis, M and Sweeney, M and Wood, N and Quinn, NP and Bhatia, KP (2006) Phenotypic homogeneity of the Huntington disease - like presentation in a SCA17 family. NEUROLOGY , 67 (9) 1701 - 1703.

Sharma, M and Mueller, JC and Zimprich, A and Lichtner, P and Hofer, A and Leitner, P and Maass, S and Berg, D and Durr, A and Bonifati, V and De Michele, G and Oostra, B and Brice, A and Wood, NW and Muller-Myhsok, B and Gasser, T and European Consortium Genetic Suscep, (2006) The sepiapterin reductase gene region reveals association in the PARK3 locus: analysis of familial and sporadic Parkinson's disease in European populations. J MED GENET , 43 (7) 557 - 562. 10.1136/jmg.2005.039149.

Wood, NW (2006) Pharmacogenetic approaches to neurological disease - Epilepsy as an example. EUR J NEUROL , 13 1 - 1.

Wood-Kaczmar, A and Gandhi, S and Wood, NW (2006) Understanding the molecular causes of Parkinson's disease. TRENDS MOL MED , 12 (11) 521 - 528. 10.1016/j.molmed.2006.09.007.

2005

Ahmadi, K.R. and Weale, M.E. and Xue, Z.Y. and Soranzo, N. and Yarnall, D.P. and Briley, J.D. and Maruyama, Y. and Kobayashi, M. and Wood, N.W. and Spurr, N.K. and Burns, D.K. and Roses, A.D. and Saunders, A.M. and Goldstein, D.B. (2005) A single-nucleotide polymorphism tagging set for human drug metabolism and transport. Nature Genetics , 37 (1) pp. 84-89. 10.1038/ng1488.

Ahmadi, KR and Weale, ME and Xue, ZYY and Soranzo, N and Yarnall, DP and Briley, JD and Maruyama, Y and Kobayashi, M and Wood, NW and Spurr, NK and Burns, DK and Roses, AD and Saunders, AM and Goldstein, DB (2005) A single-nucleotide polymorphism tagging set for human drug metabolism and transport. NAT GENET , 37 (1) 84 - 89. 10.1038/ng1488.

Bandopadhyay, R and Kingsbury, AE and Muqit, MM and Harvey, K and Reid, AR and Kilford, L and Engelender, S and Schlossmacher, MG and Wood, NW and Latchman, DS and Harvey, RJ and Lees, AJ (2005) Synphilin-1 and parkin show overlapping expression patterns in human brain and form aggresomes in response to proteasomal inhibition. NEUROBIOL DIS , 20 (2) 401 - 411. 10.1016/j.nbd.2005.03.021.

Cavalleri, GL and Lynch, JM and Depondt, C and Burley, MW and Wood, NW and Sisodiya, SM and Goldstein, DB (2005) Failure to replicate previously reported genetic associations with sporadic temporal lobe epilepsy: where to from here? BRAIN , 128 1832 - 1840. 10.1093/brain/awh524.

Cavallieri, GL and Kinirons, P and Shahwan, A and McCarthy, M and Doherty, CP and Wood, NW and Sisodiya, S and Goldstein, DB and Delanty, N (2005) Genetic variation in GABAG2 - Lessons to be learned from association studies in two large epilepsy cohorts. In: EPILEPSIA. (pp. 366 - 366). BLACKWELL PUBLISHING

Depondt, C and Cavalleri, GL and Shorvon, SD and Wood, NW and Sisodiya, SM and Goldstein, DB (2005) Association study of five sodium channel genes in epilepsy and antiepileptic drug response. In: EPILEPSIA. (pp. 90 - 91). BLACKWELL PUBLISHING

Gandhi, S and Abou-Sleiman, PM and Healy, DG and Weale, M and Gilks, W and Ahmadi, K and Goldstein, DB and Wood, NW (2005) Population genetic approaches to neurological disease: Parkinson's disease as an example. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES , 360 (1460) 1573 - 1578. 10.1098/rstb.2005.1687.
An open access publication

Gandhi, S and Muqit, M and Ganguly, M and Abou-Sleiman, PM and Wood, NW and Holton, JL and Revesz, T (2005) PINK1 protein distribution in normal human brain and Parkinson's disease. In: NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. (pp. 221 - 222). BLACKWELL PUBLISHING LTD

Gandhi, S and Wood, NW (2005) Molecular pathogenesis of Parkinson's disease. Hum Mol Genet , 14 Spec No. 2 2749 - 2755.

Gandhi, S and Wood, NW (2005) Molecular pathogenesis of Parkinson's disease. Hum Mol Genet , 14 (18) 2749 - 2755. 10.1093/hmg/ddi308.

Geser, F and Seppi, K and Stampfer-Kountchev, M and Kollensperger, M and Diem, A and Ndayisaba, JP and Ostergaard, K and Dupont, E and Cardozo, A and Tolosa, E and Abele, M and Dodel, R and Klockgether, T and Ghorayeb, I and Yekhlef, F and Tison, F and Daniels, C and Kopper, F and Deuschl, G and Coelho, M and Ferreira, J and Rosa, MM and Sampaio, C and Bozi, M and Schrag, A and Hooker, J and Kim, H and Scaravilli, T and Mathias, CJ and Fowler, C and Wood, N and Quinn, N and Widner, H and Nilsson, CF and Lindvall, O and Schimke, N and Eggert, KM and Oertel, W and del Sorbo, F and Carella, F and Albanese, A and Pellecchia, MT and Barone, P and Djaldetti, R and Meco, G and Colosimo, C and Gonzalez-Mandly, A and Berciano, J and Gurevich, T and Giladi, N and Galitzky, M and Ory, F and Rascol, O and Kamm, C and Buerk, K and Maass, S and Gasser, T and Poewe, W and Wenning, GK and EMSA-SG, (2005) The European Multiple System Atrophy-Study Group (EMSA-SG). JOURNAL OF NEURAL TRANSMISSION , 112 (12) 1677 - 1686. 10.1007/s00702-005-0328-y.

Gilks, W.P. and Abou-Sleiman, P.M. and Gandhi, S. and Jain, S. and Singleton, A. and Lees, A.J. and Shaw, K. and Bhatia, K.P. and Bonifati, V. and Quinn, N.P. and Lynch, J. and Healy, D.G. and Holton, J.L. and Revesz, T. and Wood, N.W. (2005) A common LRRK2 mutation in idiopathic Parkinson's disease. The Lancet , 365 (9457) pp. 415-416. 10.1016/S0140-6736(05)17830-1.

Gilks, WP and Abou-Sleiman, PM and Gandhi, S and Jain, S and Singleton, A and Lees, AJ and Shaw, K and Bhatia, KP and Bonifati, V and Quinn, NP and Lynch, J and Healy, DG and Holton, JL and Revesz, T and Wood, NW (2005) Common LRRK2 mutation in idiopathic Parkinson's disease. LANCET , 365 (9457) 415 - 416.

Healy, DG and Abou-Sleiman, PM and Quinn, N and Ahmadi, KR and Ozawa, T and Kamm, C and Wullner, U and Oertel, WH and Burk, K and Dupont, E and Pellecchia, MT and Tolosa, E and Gasser, T and Holton, JL and Revesz, T and Goldstein, DB and Lees, AJ and Wood, NW and European MSA Study Grp, (2005) UCHL-1 gene in multiple system atrophy: A haplotype tagging approach. MOVEMENT DISORD , 20 (10) 1338 - 1343. 10.1002/mds.20575.

Jain, S and Wood, NW and Healy, DG (2005) Molecular genetic pathways in Parkinson's disease: a review. CLIN SCI , 109 (4) 355 - 364. 10.1042/CS0050106.

Jain, S and Wood, NW and Healy, DG (2005) Molecular genetic pathways in Parkinson's disease: a review. Clin Sci (Lond) , 109 (4) 355 - 364. 10.1042/CS20050106.

Kamm, C and Healy, DG and Quinn, NP and Wullner, U and Moller, JC and Schols, L and Geser, F and Burk, K and Borglum, AD and Pellecchia, MT and Tolosa, E and del Sorbo, F and Nilsson, C and Bandmann, O and Sharma, M and Mayer, P and Gasteiger, M and Haworth, A and Ozawa, T and Lees, AJ and Short, J and Giunti, P and Holinski-Feder, E and Illig, T and Wichmann, HE and Wenning, GK and Wood, NW and Gasser, T and EMSA Study Grp, (2005) The fragile X tremor ataxia syndrome in the differential diagnosis of multiple system atrophy: data from the EMSA Study Group. BRAIN , 128 1855 - 1860. 10.1093/brain/awh535.

Khan, NL and Giunti, P and Sweeney, MG and Scherfler, C and Brien, MO and Piccini, P and Wood, NW and Lees, AJ (2005) Parkinsonism and nigrostriatal dysfunction are associated with spinocerebellar ataxia type 6 (SCA6). MOVEMENT DISORD , 20 (9) 1115 - 1119. 10.1002/mds.20564.

Khan, NL and Horta, W and Eunson, L and Graham, E and Johnson, JO and Chang, S and Davis, M and Singleton, A and Wood, NW and Lees, AJ (2005) Parkin disease in a Brazilian kindred: Manifesting heterozygotes and clinical follow-up over 10 years. MOVEMENT DISORD , 20 (4) 479 - 484. 10.1002/mds.20335.

Khan, NL and Jain, S and Lynch, JM and Pavese, N and Abou-Sleiman, P and Holton, JL and Healy, DG and Gilks, WP and Sweeney, MG and Ganguly, M and Gibbons, V and Gandhi, S and Vaughan, J and Eunson, LH and Katzenschlager, R and Gayton, J and Lennox, G and Revesz, T and Nicholl, D and Bhatia, KP and Quinn, N and Brooks, D and Lees, AJ and Davis, MB and Piccini, P and Singleton, AB and Wood, NW (2005) Mutations in the gene LRRK2 encoding dardarin (PARK8) cause familial Parkinson's disease: clinical, pathological, olfactory and functional imaging and genetic data. BRAIN , 128 2786 - 2796. 10.1093/brain/awh667.

Khan, NL and Scherfler, C and Graham, E and Bhatia, KP and Quinn, N and Lees, AJ and Brooks, DJ and Wood, NW and Piccini, P (2005) Dopaminergic dysfunction in unrelated, asymptomatic carriers of a single parkin mutation. NEUROLOGY , 64 (1) 134 - 136.

Liolitsa, D and McKenzie, M and Hargreaves, I and Heales, S and Land, J and Sisodiya, SM and Wood, NW and Duchen, MR and Hanna, MG (2005) MELAS, a young-onset stroke disorder associated with a homoplasmic ND5 mitochondrial DNA mutation. EUR J NEUROL , 12 158 - 159.

Martinez, M and Brice, A and Vaughan, JR and Zimprich, A and Breteler, MMB and Meco, G and Filla, A and Farrer, MJ and Betard, C and Singleton, A and Hardy, J and De Michele, G and Bonifati, V and Oostra, BA and Gasser, T and Wood, NW and Durr, A and French Parkinson's Disease, (2005) Apolipoprotein E4 is probably responsible for the chromosome 19 linkage peak for Parkinson's disease. AM J MED GENET B , 136B (1) 72 - 74. 10.1002/ajmg.b.30196.

Morris, HR and Wood, NW and Lees, AJ (2005) Progressive supranuclear palsy (Steele-Richardson-Olszewski disease). In: Morris, H, (ed.) Neurology update: reviews for continuing professional development. (185 - 196). Radcliffe Publishing: Oxford.

Ozawa, T and Paviour, D and Quinn, NP and Lees, AJ and Josephs, KA and Healy, DG and Wood, NW and Holton, JL and Revesz, T (2005) The spectrum of pathological involvement of multiple system atrophy (MSA): clinicopathological correlations. In: NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. (pp. 244 - 244). BLACKWELL PUBLISHING LTD

Pittman, AM and Myers, AJ and Abou-Sleiman, P and Fung, HC and Kaleem, M and Marlowe, L and Duckworth, J and Leung, D and Williams, D and Kilford, L and Thomas, N and Morris, CM and Dickson, D and Wood, NW and Hardy, J and Lees, AJ and de Silva, R (2005) Linkage disequilibrium fine mapping and haplotype association analysis of the tau gene in progressive supranuclear palsy and corticobasal degeneration. J MED GENET , 42 (11) 837 - 846. 10.1136/jmg.2005.031377.
An open access publication

Prestel, J and Sharma, M and Leitner, P and Zimprich, A and Vaughan, JR and Durr, A and Bonifati, V and De Michele, G and Hanagasi, HA and Farrer, M and Hofer, A and Asmus, F and Volpe, G and Meco, G and Brice, A and Wood, NW and Muller-Myhsok, B and Gasser, T and GSPD, (2005) PARK11 is not linked with Parkinson's disease in European families. EUR J HUM GENET , 13 (2) 193 - 197. 10.1038/sj.ejhg.5201317.

Sisodiya, S and Soranzo, N and Wood, NW and Goldstein, DB (2005) Association of genetic loci: replication or not, that is the question. Neurology , 64 (11) 1989 - ?.

Stumpf, MPH and Goldstein, DB and Wood, NW (2005) Introduction: genetic variation and human health. PHILOS T R SOC B , 360 (1460) 1539 - 1541. 10.1098/rstb.2005.1694.

Tate, SK and Depondt, C and Sisodiya, SM and Cavalleri, GL and Schorge, S and Soranzo, N and Thom, M and Sen, A and Shorvon, SD and Sander, JW and Wood, NW and Goldstein, DB (2005) Genetic predictors of the maximum doses patients receive during clinical use of the anti-epileptic drugs carbamazepine and phenytoin. P NATL ACAD SCI USA , 102 (15) 5507 - 5512. 10.1073/pnas.0407346102.
An open access publication

Wood, NW and Healy, DG and Depondt, C and Abou-Sleiman, PM (2005) Commentary on "A genome wide linkage disequilibrium screen in Parkinson's disease" By Foltynie et al. in J Neurol (2005)252:597-602. J NEUROL , 252 (5) 603 - 604. 10.1007/s00415-005-0707-1.

2004

Abou-Sleiman, PM and Healy, DG and Wood, NW (2004) Causes of Parkinson's disease: genetics of DJ-1. CELL TISSUE RES , 318 (1) 185 - 188. 10.1007/s00441-004-0922-6.

Abou-Sleiman, PM and Healy, DG and Wood, NW (2004) Genetic approaches to solving common diseases. J NEUROL , 251 (10) 1169 - 1172. 10.1007/s00415-004-0518-9.

Ansorge, O and Giunti, P and Michalik, A and Van Broeckhoven, C and Harding, B and Wood, N and Scaravilli, F (2004) Ataxin-7 aggregation and ubiquitination in infantile SCA7 with 180 CAG repeats. ANN NEUROL , 56 (3) 448 - 452.

Bandopadhyay, R and Kingsbury, AE and Cookson, MR and Reid, AR and Evans, IM and Hope, AD and Pittman, AM and Lashley, T and Canet-Aviles, R and Miller, DW and McLendon, C and Strand, C and Leonard, AJ and Abou-Sleiman, PM and Healy, DG and Ariga, H and Wood, NW and de Silva, R and Revesz, T and Hardy, JA and Lees, AJ (2004) The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease. BRAIN , 127 420 - 430. 10.1093/brain/awh054.

Beck, J.A. and Poulter, M. and Campbell, T.A. and Uphill, J.B. and Adamson, G. and Geddes, J.F. and Revesz, T. and Davis, M.B. and Wood, N.W. and Collinge, J. and Tabrizi, S.J. (2004) Somatic and germline mosaicism in sporadic early-onset Alzheimer's disease. Human Molecular Genetics , 13 (12) pp. 1219-1224. 10.1093/hmg/ddh134.

Beck, JA and Poulter, M and Campbell, T and Uphill, JB and Adamson, G and Geddes, JF and Revesz, T and Davis, M and Wood, NW and Collinge, J and Tabrizi, SJ (2004) Nuclear somatic mosaicism in sporadic early-onset Alzheimer's disease. In: NEUROBIOLOGY OF AGING. (pp. S54 - S54). ELSEVIER SCIENCE INC

Beck, JA and Poulter, M and Campbell, TA and Uphill, JB and Adamson, G and Geddes, JF and Revesz, T and Davis, MB and Wood, NW and Collinge, J and Tabrizi, SJ (2004) Somatic and germline mosaicism in sporadic early-onset Alzheimer's disease. HUM MOL GENET , 13 (12) 1219 - 1224. 10.1093/hmg/ddh134.

Depondt, C and Cavalleri, G and Weale, ME and Burly, MW and Cock, H and Shorvon, SD and Sisodiya, S and Wood, NW and Goldstein, DB (2004) Common variation in the SCN1A gene is a risk factor for common forms of epilepsy associated with febrile seizures. In: EPILEPSIA. (pp. 120 - 120). BLACKWELL PUBLISHING INC

Depondt, C and Cock, HR and Healy, DG and Burley, MW and Weinshenker, D and Wood, NW and Goldstein, DB and Sisodiya, SM (2004) The -1021C -> T DBH gene variant is not associated with epilepsy or antiepileptic drug response. NEUROLOGY , 63 (8) 1497 - 1499.

Everett, CM and Wood, NW (2004) Trinucleotide repeats and neurodegenerative disease. BRAIN , 127 2385 - 2405. 10.1093/brain/awh278.

Healy, DG and Abou-Sleiman, PM and Ahmadi, KR and Muqit, MMK and Bhatia, KP and Quinn, NP and Lees, AJ and Latchmann, DS and Goldstein, DB and Wood, NW (2004) The gene responsible for PARK6 Parkinson's disease, PINK1, does not influence common forms of parkinsonism. ANN NEUROL , 56 (3) 329 - 335.

Healy, DG and Abou-Sleiman, PM and Gibson, JM and Ross, OA and Jain, S and Gandhi, S and Gosal, D and Muqit, MMK and Wood, NW and Lynch, T (2004) PINK1 (PARK6) associated Parkinson disease in Ireland. NEUROLOGY , 63 (8) 1486 - 1488.

Healy, DG and Abou-Sleiman, PM and Lees, AJ and Casas, JP and Quinn, N and Bhatia, K and Hingorani, AD and Wood, NW (2004) Tau gene and Parkinson's disease: a case-control study and meta-analysis. J NEUROL NEUROSUR PS , 75 (7) 962 - 965. 10.1136/jnnp.2003.026203.

Healy, DG and Abou-Sleiman, PM and Ozawa, T and Lees, AJ and Bhatia, K and Ahmadi, KR and Wullner, U and Berciano, J and Moller, JC and Kamm, C and Burk, K and Barrone, P and Tolosa, E and Quinn, N and Goldstein, DB and Wood, NW (2004) A functional polymorphism regulating dopamine beta-hydroxylase influences against Parkinson's disease. ANN NEUROL , 55 (3) 443 - 446.

Healy, DG and Abou-Sleiman, PM and Valente, EM and Gilks, WP and Bhatia, K and Quinn, N and Lees, AJ and Wood, NW (2004) DJ-1 mutations in Parkinson's disease. J NEUROL NEUROSUR PS , 75 (1) 144 - 145.

Healy, DG and Abou-Sleiman, PM and Wood, NW (2004) PINK, PANK, or PARK? A clinicians' guide to familial parkinsonism. LANCET NEUROL , 3 (11) 652 - 662.

Healy, DG and Abou-Sleiman, PM and Wood, NW (2004) Genetic causes of Parkinson's disease: UCHL-1. CELL TISSUE RES , 318 (1) 189 - 194. 10.1007/s00441-004-0917-3.

Healy, DG and Wood, NW (2004) Clinical picture of bilateral vestibular schwannomas, sudden bilateral hearing loss, and aviation. NEUROLOGY , 63 (5) 933 - 933.

Houlden, H and Girard, M and Cockerell, C and Ingram, D and Wood, NW and Goossens, M and Walker, RWH and Reilly, MM (2004) Connexin 32 promoter P2 mutations: A mechanism of peripheral nerve dysfunction. ANN NEUROL , 56 (5) 730 - 734. 10.1002/ana.20267.

Khan, NL and Katzenschlager, R and Watt, H and Bhatia, KP and Wood, NW and Quinn, N and Lees, AJ (2004) Olfaction differentiates parkin disease from early-onset parkinsonism and Parkinson disease. NEUROLOGY , 62 (7) 1224 - 1226.

Lee, MJ and Stephenson, D and Groves, M and Sweeney, M and Davis, M and An, SF and Houlden, H and Scaravilli, F and Wood, N and Reilly, M (2004) Sensory deprivation is associated with a mutation in the rat chaperonin delta subunit. In: GENETICAL RESEARCH. (pp. 120 - 120). CAMBRIDGE UNIV PRESS

MacCormac, LP and Muqit, MMK and Faulkes, DJ and Wood, NW and Latchman, DS (2004) Reduction in endogenous parkin levels renders glial cells sensitive to both caspase-dependent and caspase-independent cell death. EUR J NEUROSCI , 20 (8) 2038 - 2048. 10.1111/j.1460-9568.2004.03659.x.

Mantuano, E and Veneziano, L and Spadaro, M and Giunti, P and Guida, S and Leggio, MG and Verriello, L and Wood, N and Jodice, C and Frontali, M (2004) Clusters of non-truncating mutations of P/Q type Ca2+ channel subunit Ca(v)2.1 causing episodic ataxia 2. J MED GENET , 41 (6) , Article e82. 10.1136/jmg.2003.015396.

Martinez, M and Brice, A and Vaughan, JR and Zimprich, A and Breteler, MMB and Meco, G and Filla, A and Farrer, MJ and Betard, C and Hardy, J and De Michele, G and Bonifati, V and Oostra, B and Gasser, T and Wood, NW and Durr, A and French Parkinsons Dis Genetics Stu, and European Consortium Genetic Susc, (2004) Genome-wide scan linkage analysis for Parkinson's disease: the European genetic study of Parkinson's disease. J MED GENET , 41 (12) 900 - 907. 10.1136/jmg.2004.022632.

Morris, HR and Steele, JC and Crook, R and Wavrant-De Vrieze, F and Onstead-Cardinale, L and Gwinn-Hardy, K and Wood, NW and Farrer, M and Lees, AJ and McGeer, PL and Siddique, T and Hardy, J and Perez-Tur, J (2004) Genome-wide analysis of the Parkinsonism-dementia complex of Guam. ARCH NEUROL-CHICAGO , 61 (12) 1889 - 1897.

Muqit, MMK and Davidson, SM and Smith, MDP and MacCormac, LP and Kahns, S and Jensen, PH and Wood, NW and Latchman, DS (2004) Parkin is recruited into aggresomes in a stress-specific manner: over-expression of parkin reduces aggresome formation but can be dissociated from parkin's effect on neuronal survival. HUM MOL GENET , 13 (1) 117 - 135. 10.1093/hmg/ddh012.

Myers, AJ and Pittman, A and Duckworth, J and Fung, P and Evans, J and Evans, W and Bryden, L and Hanson, M and Abou-Sleiman, P and Wood, NW and Lees, A and de Silva, R and Hardy, JA (2004) Investigation of the microtubule associated protein tau locus. In: AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. (pp. 16 - 16). WILEY-LISS

Ozawa, T and Paviour, D and Quinn, NP and Josephs, KA and Sangha, H and Kilford, L and Healy, DG and Wood, NW and Lees, AJ and Holton, JL and Revesz, T (2004) The spectrum of pathological involvement of the striatonigral and olivopontocerebellar systems in multiple system atrophy: clinicopathological correlations. BRAIN , 127 2657 - 2671. 10.1093/brain/awh303.

Ozawa, T. and Paviour, D. and Quinn, N.P. and Josephs, K.A. and Sangha, D. and Kilford, L. and Healy, D.G. and Wood, N.W. and Lees, A.J. and Holton, J.L. and Revesz, T. (2004) The spectrum of pathological involvement of the striatonigral and olivopontocerebellar systems in multiple system atrophy: clinicopathological correlations. Brain , 127 (12) pp. 2657-2671. 10.1093/brain/awh303.

Paisan-Ruiz, C and Jain, S and Evans, EW and Gilks, WP and Simon, J and van der Brug, M and de Munain, AL and Aparicio, S and Gil, AM and Khan, N and Johnson, J and Martinez, JR and Nicholl, D and Carrera, IM and Pena, AS and de Silva, R and Lees, A and Marti-Masso, JF and Perez-Tur, J and Wood, NW and Singleton, AB (2004) Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease. NEURON , 44 (4) 595 - 600.

Pittman, A.M. and Myers, A.J. and Duckworth, J. and Bryden, L. and Hanson, M. and Abou-Sleiman, P. and Wood, N.W. and Hardy, J. and Lees, A. and de Silva, R. (2004) The structure of the tau haplotype in controls and in progressive supranuclear palsy. Human Molecular Genetics , 13 (12) pp. 1267-1274. 10.1093/hmg/ddh138.

Pittman, AM and Myers, AJ and Duckworth, J and Bryden, L and Hanson, M and Abou-Sleiman, P and Wood, NW and Hardy, J and Lees, A and de Silva, R (2004) The structure of the tau haplotype in controls and in progressive supranuclear palsy. HUM MOL GENET , 13 (12) 1267 - 1274. 10.1093/hmg/ddh138.

Scherfler, C and Khan, NL and Pavese, N and Eunson, L and Graham, E and Lees, AJ and Quinn, NP and Wood, NW and Brooks, DJ and Piccini, PP (2004) Striatal and cortical pre- and postsynaptic dopaminergic dysfunction in sporadic parkin-linked parkinsonism. BRAIN , 127 1332 - 1342. 10.1093/brain/awh150.

Sinha, KK and Worth, PF and Jha, DK and Sinha, S and Stinton, VJ and Davis, MB and Wood, NW and Sweeney, MG and Bhatia, KP (2004) Autosomal dominant cerebellar ataxia: SCA2 is the most frequent mutation in eastern India. J NEUROL NEUROSUR PS , 75 (3) 448 - 452. 10.1136/jnnp.2002.004895.

Soranzo, N and Cavalleri, GL and Weale, ME and Wood, NW and Depondt, C and Marguerie, R and Sisodiya, SM and Goldstein, DB (2004) Identifying candidate causal variants responsible for altered activity of the ABCB1 multidrug resistance gene. GENOME RES , 14 (7) 1333 - 1344.

Soranzo, N. and Cavalleri, G.L. and Weale, M.E. and Wood, N.W. and Depondt, C. and Marguerie, R. and Sisodiya, S.M. and Goldstein, D.B. (2004) Identifying candidate causal variants responsible for altered activity of the ABCB1 multidrug resistance gene. Genome Research , 14 (7) pp. 1333-1344. 10.1101/gr.1965304.
An open access version is available from UCL Discovery

Tabrizi, SJ and Beck, JA and Poulter, M and Campbell, T and Uphill, JB and Adamson, G and Geddes, JF and Revesz, T and Davis, M and Wood, N and Collinge, J (2004) Somatic mosaicism in sporadic early-onset Alzheimer's disease. In: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. (pp. 1216 - 1216). B M J PUBLISHING GROUP

Valente, EM and Abou-Sleiman, PM and Caputo, V and Muqit, MMK and Gispert, S and Ali, Z and Del Turco, D and Wingerter, O and Bentivoglio, AR and Healy, DG and Albanese, A and Nussbaum, R and Gonzalez-Maldonado, R and Deller, T and Mulsch, A and Bratzke, H and Salvi, S and Cortelli, P and Gilks, WP and Latchman, D and Harvey, R and Dallapiccola, B and Auburger, G and Wood, NW (2004) PARK6 linked Parkinson's disease is caused by mutations in a mitochondrial protein kinase. JOURNAL OF NEUROLOGY , 251 50 - 50.

Valente, EM and Abou-Sleiman, PM and Caputo, V and Muqit, MMK and Harvey, K and Gispert, S and Ali, Z and Del Turco, D and Bentivoglio, AR and Healy, DG and Albanese, A and Nussbaum, R and Gonzalez-Maldonaldo, R and Deller, T and Salvi, S and Cortelli, P and Gilks, WP and Latchman, DS and Harvey, RJ and Dallapiccola, B and Auburger, G and Wood, NW (2004) Hereditary early-onset Parkinson's disease caused by mutations in PINK1. SCIENCE , 304 (5674) 1158 - 1160. 10.1126/science.1096284.

Valente, EM and Abou-Sleiman, PM and Caputo, V and Muqit, MMK and Harvey, K and Gispert, S and Zeeshani, A and Del Turco, D and Bentivoglio, AR and Healy, DG and Albanese, A and Nussbaum, R and Gonzalez-Maldonado, R and Deller, T and Salvi, S and Cortelli, P and Gilks, WP and Latchman, DS and Harvey, RJ and Dallapiccola, B and Auburger, G and Wood, NW (2004) Identification of PINK1, the first mitochondrial gene causing Parkinson's disease. EUR J NEUROL , 11 366 - 367.

Wilkinson, PA and Crosby, AH and Turner, C and Bradley, LJ and Ginsberg, L and Wood, NW and Schapira, AH and Warner, TT (2004) A clinical, genetic and biochemical study of SPG7 mutations in hereditary spastic paraplegia. BRAIN , 127 973 - 980. 10.1093/brain/awh125.

Wood, N and Muqit, M (2004) Identification of PINK1 (PARK6), the first mitochondrial gene causing Parkinson's disease. In: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. (pp. 1220 - 1220). B M J PUBLISHING GROUP

2003

Abou-Sleiman, PM and Healy, DG and Ahmadi, K and Goldstein, DB and Wood, NW (2003) Population genetic approaches to Parkinsons disease. In: AMERICAN JOURNAL OF HUMAN GENETICS. (pp. 541 - 541). UNIV CHICAGO PRESS

Abou-Sleiman, PM and Healy, DG and Quinn, N and Lees, AJ and Wood, NW (2003) The role of pathogenic DJ-1 mutations in Parkinson's disease. ANN NEUROL , 54 (3) 283 - 286. 10.1002/ana.10675.

de Silva, R and Hope, A and Pittman, A and Weale, ME and Morris, HR and Wood, NW and Lees, AJ (2003) Strong association of the Saitohin gene Q7 variant with progressive supranuclear palsy. NEUROLOGY , 61 (3) 407 - 409.

de Silva, R and Lashley, T and Gibb, G and Hanger, D and Hope, A and Reid, A and Bandopadhyay, R and Utton, M and Strand, C and Jowett, T and Khan, N and Anderton, B and Wood, N and Holton, J and Revesz, T and Lees, A (2003) Pathological inclusion bodies in tauopathies contain distinct complements of tau with three or four microtubule-binding repeat domains as demonstrated by new specific monoclonal antibodies. NEUROPATH APPL NEURO , 29 (3) 288 - 302.

Edwards, M and Wood, N and Bhatia, K (2003) Unusual phenotypes in DYT1 dystonia: A report of five cases and a review of the literature. MOVEMENT DISORD , 18 (6) 706 - 711. 10.1002/mds.10411.

Edwards, M and Wood, N and Bhatia, K (2003) Unusual phenotypes in DYT1 dystonia: A report of five cases and a review of the literature. Movement Disorders , 18 (6) 706 - 711.

Edwards, MJ and Huang, YZ and Wood, NW and Rothwell, JC and Bhatia, KP (2003) Different patterns of electrophysiological deficits in manifesting and non-manifesting carriers of the DYT1 gene mutation. BRAIN , 126 2074 - 2080. 10.1093/brain/awg209.

Goldstein, D.B. and Ahmadi, K.R. and Weale, M.E. and Wood, N.W. (2003) Genome scans and candidate gene approaches in the study of common diseases and variable drug responses. Trends in Genetics , 19 (11) pp. 615-622. 10.1016/j.tig.2003.09.006.

Goldstein, DB and Ahmadi, KR and Weale, ME and Wood, NW (2003) Genome scans and candidate gene approaches in the study of common diseases and variable drug responses. TRENDS GENET , 19 (11) 615 - 622. 10.1016/j.tig.2003.09.006.

Hadjivassiliou, M and Grunewald, R and Sharrack, B and Sanders, D and Lobo, A and Williamson, C and Woodroofe, N and Wood, N and Davies-Jones, A (2003) Gluten ataxia in perspective: epidemiology, genetic susceptibility and clinical characteristics. BRAIN , 126 685 - 691. 10.1093/brain/awg050.

Khan, NL and Graham, E and Critchley, P and Schrag, AE and Wood, NW and Lees, AJ and Bhatia, KP and Quinn, N (2003) Parkin disease: a phenotypic study of a large case series. BRAIN , 126 1279 - 1292. 10.1093/brain/awg142.

Khan, NL and Wood, NW and Bhatia, KP (2003) Autosomal recessive, DYT2-like primary torsion dystonia - A new family. NEUROLOGY , 61 (12) 1801 - 1803.

Kuoppamaki, M and Giunti, P and Quinn, N and Wood, NW and Bhatia, KP (2003) Slowly progressive cerebellar ataxia and cervical dystonia: Clinical presentation of a new form of spinocerebellar ataxia? MOVEMENT DISORD , 18 (2) 200 - 206. 10.1002/mds.10308.

Lee, M.-J. and Stephenson, D.A. and Groves, M.J. and Sweeney, M.G. and Davis, M.B. and An, S.-F. and Houlden, H. and Salih, M.A.M. and Timmerman, V. and De Jonghe, P. and Auer-Grumbach, M. and Di Maria, E. and Scaravilli, F. and Wood, N.W. and Reilly, M.M. (2003) Hereditary sensory neuropathy is caused by a mutation in the delta subunit of the cytosolic chaperonin-containing t-complex peptide-1 (Cct4 ) gene. Human Molecular Genetics , 12 (15) pp. 1917-1925. 10.1093/hmg/ddg198.

Lee, MJ and Stephenson, DA and Groves, MJ and Sweeney, MG and Davis, MB and An, SF and Houlden, H and Salih, MAM and Timmerman, V and de Jonghe, P and Auer-Grumbach, M and Di Maria, E and Scaravilli, F and Wood, NW and Reilly, MM (2003) Hereditary sensory neuropathy is caused by a mutation in the delta subunit of the cytosolic chaperonin-containing t-complex peptide-1 (Cct4) gene. HUM MOL GENET , 12 (15) 1917 - 1925. 10.1093/hmg/ddg198.

Lohmann, E and Periquet, M and Bonifati, V and Wood, NW and De Michele, G and Bonnet, AM and Fraix, V and Broussolle, E and Horstink, MWIM and Vidailhet, M and Verpillat, P and Gasser, T and Nicholl, D and Teive, H and Raskin, S and Rascol, O and Destee, A and Ruberg, M and Gasparini, F and Meco, G and Agid, Y and Durr, A and Brice, A and French Parkinsons Dis Genetics Stu, and European Consortium Genetic Suscep, (2003) How much phenotypic variation can be attributed to parkin genotype? ANN NEUROL , 54 (2) 176 - 185. 10.1002/ana.10613.

Morris, HR and Osaki, Y and Holton, J and Lees, AJ and Wood, NW and Revesz, T and Quinn, N (2003) Tau exon 10 +16 mutation FTDP-17 presenting clinically as sporadic young onset PSP. NEUROLOGY , 61 (1) 102 - 104.

Periquet, M and Latouche, M and Lohmann, E and Rawal, N and De Michele, G and Ricard, S and Teive, H and Fraix, V and Vidailhet, M and Nicholl, D and Barone, P and Wood, NW and Raskin, S and Deleuze, JF and Agid, Y and Durr, A and Brice, A and French Parkinsons Dis Genetics Stu, and European Consortium Genetic Suscep, (2003) Parkin mutations are frequent in patients with isolated early-onset parkinsonism. BRAIN , 126 1271 - 1278. 10.1093/brain/awg136.

Sibbing, D and Trender-Gerhardt, I and Wood, NW and Oertel, WH and Bhatia, KP and Bandmann, O (2003) The promoter region of the Menkes gene ATP7A is not altered in focal or generalized dystonia. ANN NEUROL , 53 (2) 278 - 279. 10.1002/ana.10436.

Siddiqui, A and Kerb, R and Weale, ME and Brinkmann, U and Smith, A and Goldstein, DB and Wood, NW and Sisodiya, SM (2003) Association of multidrug resistance in epilepsy with a polymorphism in the drug-transporter gene ABCB1. NEW ENGL J MED , 348 (15) 1442 - 1448.

Weale, ME and Depondt, C and Macdonald, SJ and Smith, A and Lai, PS and Shorvon, SD and Wood, NW and Goldstein, DB (2003) Selection and evaluation of tagging SNPs in the neuronal-sodium-channel gene SCN1A: Implications for linkage-disequilibrium gene mapping. AM J HUM GENET , 73 (3) 551 - 565.

Wilkinson, PA and Crosby, AH and Turner, C and Patel, H and Wood, NW and Schapira, AH and Warner, TT (2003) A clinical and genetic study of SPG5A linked autosomal recessive hereditary spastic paraplegia. NEUROLOGY , 61 (2) 235 - 238.

Wood, N (2003) Principles of genetic counselling. In: EPILEPSIA. (pp. 9 - 9). BLACKWELL PUBLISHING INC

Wood, NW (2003) Ataxic disorders. In: Warrell, DA and Cox, TM and Firth, JD and Benz, EJ, (eds.) Oxford Textbook of Medicine. (1068 - 1074). Oxford University Press: Oxford.

Wood, NW (2003) Neurogenetics. In: Warrell, DA and Cox, TM and Firth, JD and Benz, EJ, (eds.) Oxford Textbook of Medicine. (945 - 952). Oxford University Press: Oxford.

Wood, NW (2003) Neurogenetics. In: Fowler, TJ and Scadding, JW, (eds.) Clinical neurology. (119 - 129). Arnold: London.

Worth, PF and Wood, NW (2003) A systematic and structured approach to the investigation of ataxia. In: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. (pp. 1166 - 1166). BRITISH MED JOURNAL PUBL GROUP

2002

Asmus, F and Zimprich, A and du Montcel, ST and Kabus, C and Deuschl, G and Kupsch, A and Ziemann, U and Castro, M and Kuhn, AA and Strom, TM and Vidailhet, M and Bhatia, KP and Durr, A and Wood, NW and Brice, A and Gasser, T (2002) Myoclonus-dystonia syndrome: epsilon-sarcoglycan mutations and phenotype. ANN NEUROL , 52 (4) 489 - 492. 10.1002/ana.10325.

Bajaj, NPS and Waldman, A and Orrell, R and Wood, NW and Bhatia, KP (2002) Familial adult onset of Krabbe's disease resembling hereditary spastic paraplegia with normal neuroimaging. J NEUROL NEUROSUR PS , 72 (5) 635 - 638.

Bandmann, O and Wood, NW (2002) Dopa-responsive dystonia -- the story so far. Neuropediatrics , 33 (1) 1 - 5.

de Silva, R and Hardy, J and Crook, J and Khan, N and Graham, EA and Morris, CM and Wood, NW and Lees, AJ (2002) The tau locus is not significantly associated with pathologically confirmed sporadic Parkinson's disease. NEUROSCI LETT , 330 (2) 201 - 203.

Dobson-Stone, C and Danek, A and Rampoldi, L and Hardie, RJ and Chalmers, RM and Wood, NW and Bohlega, S and Dotti, MT and Federico, A and Shizuka, M and Tanaka, M and Watanabe, M and Ikeda, Y and Brin, M and Goldfarb, LG and Karp, BI and Mohiddin, S and Fananapazir, L and Storch, A and Fryer, AE and Maddison, P and Sibon, I and Trevisol-Bittencourt, PC and Singer, C and Caballero, IR and Aasly, JO and Schmierer, K and Dengler, R and Hiersemenzel, LP and Zeviani, M and Meiner, V and Lossos, A and Johnson, S and Mercado, FC and Sorrentino, G and Dupre, N and Rouleau, GA and Volkmann, J and Arpa, J and Lees, A and Geraud, G and Chouinard, S and Nemeth, A and Monaco, AP (2002) Mutational spectrum of the CHAC gene in patients with chorea-acanthocytosis. EUR J HUM GENET , 10 (11) 773 - +. 10.1038/sj/ejhg.5200866.

Eunson, L and Khan, NL and Quinn, N and Bhatia, K and Wood, NW and Davis, MB (2002) Novel parkin mutations in early-onset parkinsonism. In: JOURNAL OF MEDICAL GENETICS. (pp. S71 - S71). BRITISH MED JOURNAL PUBL GROUP

Everett, CM and Saveliev, A and Webster, Z and Wood, NW and Festenstein, R (2002) The molecular basis for aberrant gene regulation in Friedreich's ataxia. J NEUROL NEUROSUR PS , 73 (2) 225 - 225.

Gabriel, CM and Gregson, NA and Wood, NW and Hughes, RAC (2002) Immunological study of hereditary motor and sensory neuropathy type 1 a (HMSN1 a). J NEUROL NEUROSUR PS , 72 (2) 230 - 235.

Goldstein, DB and Ramachandran, V and Wood, N and Shorvon, S (2002) Pharmacogenomics of neurological disorders. In: Pharmacogenomics: The search for Individualised Therapies.

Hafezparast, M and Ahmad-Annuar, A and Wood, NW and Tabrizi, SJ and Fisher, EMC (2002) Mouse models for neurological disease. LANCET NEUROL , 1 (4) 215 - 224.

Hanna, MG and Wood, NW (2002) Running a neurogenetic clinic. J NEUROL NEUROSUR PS , 73 2 - 4.

Houlden, H and Roper, H and Willis, T and Schenone, A and Di Battista, C and Wood, NW and Reilly, M (2002) Giant axonal neuropathy is caused by mutations in the gigaxonin gene: Clinical, genetic, and pathological characterisation of three families. J NEUROL NEUROSUR PS , 73 (2) 225 - 225.

Houlden, H and Smith, S and de Carvalho, M and Blake, J and Mathias, C and Wood, NW and Reilly, MM (2002) Clinical and genetic characterization of families with triple A (Allgrove) syndrome. BRAIN , 125 2681 - 2690.

Houlden, H and Smith, S and de Carvalho, M and Mathias, C and Blake, J and Wood, NW and Reilly, M (2002) Clinical and genetic characterisation of families with triple a (Allgrove) syndrome. J NEUROL NEUROSUR PS , 73 (2) 225 - 225.

Janssen, JC and Warrington, EK and Morris, HR and Lantos, P and Brown, J and Revesz, T and Wood, N and Khan, MN and Cipolotti, L and Fox, NC and Rossor, MN (2002) Clinical features of frontotemporal dementia due to the intronic tau 10(+16) mutation. NEUROLOGY , 58 (8) 1161 - 1168.

Jarman, PR and Wood, NW (2002) Genetics of movement disorders and ataxia. Journal of Neurology, Neurosurgery and Psychiatry , 73 (Suppl.2) II22 - II26.

Jarman, PR and Wood, NW (2002) Genetics of movement disorders and ataxia. J NEUROL NEUROSUR PS , 73 22 - 26.

Khan, N and Valente, EM and Brooks, DJ and Piccini, P and Bhatia, KP and Quinn, NP and Wood, NW (2002) The genetic basis and phenotypic variability in early onset parkinsonism. J NEUROL NEUROSUR PS , 73 (2) 213 - 213.

Khan, NL and Brooks, DJ and Pavese, N and Sweeney, MG and Wood, NW and Lees, AJ and Piccini, P (2002) Progression of nigrostriatal dysfunction in a parkin kindred: an [F-18] dopa PET and clinical study. BRAIN , 125 2248 - 2256.

Khan, NL and Brooks, DJ and Pavese, N and Wood, NW and Lees, AJ and Piccini, P (2002) Progression of nigrostriatal dysfunction in a parkin kindred: An F-18-dopa PET and clinical study. J NEUROL NEUROSUR PS , 72 (1) 134 - 134.

Khan, NL and Valente, EM and Bentivoglio, AR and Wood, NW and Albanese, A and Brooks, DJ and Piccini, P (2002) Clinical and subclinical dopaminergic dysfunction in PARK6-linked parkinsonism: An F-18-dopa PET study. ANN NEUROL , 52 (6) 849 - 853. 10.1002/ana.10417.

Kinton, L and Johnson, MR and Smith, SJM and Farrell, F and Stevens, J and Rance, JB and Claudino, AM and Duncan, JS and Davis, MB and Wood, NW and Sander, JWA (2002) Partial epilepsy with pericentral spikes: A new familial epilepsy syndrome with evidence for linkage to chromosome 4p15. ANN NEUROL , 51 (6) 740 - 749. 10.1002/ana.10221.

Lee, MJ and Huang, YC and Sweeney, MG and Wood, NW and Reilly, MM and Yip, PK (2002) Mutation of the sterol 27-hydroxylase gene (CYP27A1) in a Taiwanese family with cerebrotendinous xanthomatosis. J NEUROL , 249 (9) 1311 - 1312. 10.1007/s00415-002-0762-9.

Lee, MJ and Nelson, I and Houlden, H and Sweeney, MG and Hilton-Jones, D and Blake, J and Wood, NW and Reilly, MM (2002) Six novel connexin32 (GJB1) mutations in X-linked Charcot-Marie-Tooth disease. J NEUROL NEUROSUR PS , 73 (3) 304 - 306.

McCabe, DJH and Wood, NW and Ryan, F and Hanna, MG and Connolly, S and Moore, DP and Redmond, J and Barton, DE and Murphy, RP (2002) Intrafamilial phenotypic variability in Friedreich ataxia associated with a G130V mutation in the FRDA gene. ARCH NEUROL-CHICAGO , 59 (2) 296 - 300.

Misbahuddin, A and Placzek, MR and Chaudhuri, KR and Wood, NW and Bhatia, KP and Warner, TT (2002) A polymorphism in the dopamine receptor DRD5 is associated with blepharospasm. NEUROLOGY , 58 (1) 124 - 126.

Morris, H.R. and Gibb, G. and Katzenschlager, R. and Wood, N.W. and Hanger, D.P. and Strand, C. and Lashley, T. and Daniel, S.E. and Lees, A.J. and Anderton, B.H. and Revesz, T. (2002) Pathological, clinical and genetic heterogeneity in progressive supranuclear palsy. Brain , 125 (5) pp. 969-975. 10.1093/brain/awf109.

Morris, HR and Baker, M and Yasojima, K and Houlden, H and Khan, MN and Wood, NW and Hardy, J and Grossman, M and Trojanowski, J and Revesz, T and Bigio, EH and Bergeron, C and Janssen, JC and McGeer, PL and Rossor, MN and Lees, AJ and Lantos, PL and Hutton, M (2002) Analysis of tau haplotypes in Pick's disease. NEUROLOGY , 59 (3) 443 - 445.

Morris, HR and Gibb, G and Katzenschlager, R and Wood, NW and Hanger, DP and Strand, C and Lashley, T and Daniel, SE and Lees, AJ and Anderton, BH and Revesz, T (2002) Pathological, clinical and genetic heterogeneity in progressive supranuclear palsy. BRAIN , 125 969 - 975.

Morris, HR and Katzenschlager, R and Janssen, JC and Brown, JM and Ozansoy, M and Quinn, N and Revesz, T and Rossor, MN and Daniel, SE and Wood, NW and Lees, AJ (2002) Sequence analysis of tau in familial and sporadic progressive supranuclear palsy. J NEUROL NEUROSUR PS , 72 (3) 388 - 390.

Nicholl, DJ and Vaughan, JR and Khan, NL and Ho, SL and Aldous, DEW and Lincoln, S and Farrer, M and Gayton, JD and Davis, MB and Piccini, P and Daniel, SE and Lennox, GG and Brooks, DJ and Williams, AC and Wood, NW (2002) Two large British kindreds with familial Parkinson's disease: A clinico-pathological and genetic study. BRAIN , 125 44 - 57.

Pang, JT and Giunti, P and Chamberlain, S and An, SF and Vitaliani, R and Scaravilli, T and Martinian, L and Wood, NW and Scaravilli, F and Ansorge, O (2002) Neuronal intranuclear inclusions in SCA2: a genetic, morphological and immunohistochemical study of two cases. BRAIN , 125 656 - 663.

Siddiqui, A and Davis, M and Dixon, PH and Johnson, M and Koepp, M and Shorvon, SD and Sander, JWA and Gardiner, RM and Duncan, JS and Wood, NW (2002) Mapping the disease locus in a large kindred with generalised epilepsy. J NEUROL NEUROSUR PS , 72 (1) 141 - 142.

Siddiqui, A and Johnson, M and Dixon, M and Koepp, M and Shorvon, SD and Sander, JWA and Gardiner, RM and Duncan, JS and Wood, NW (2002) A novel locus on chromosome 2p 14-21 in a British family with generalised epilepsy and febrile seizures. J NEUROL NEUROSUR PS , 73 (2) 224 - 224.

Spacey, SD and Szczygielski, BI and McRory, JE and Wali, GM and Wood, NW and Snutch, TP (2002) Mutation analysis of the sodium/hydrogen exchanger gene (NHE5) in familial paroxysmal kinesigenic dyskinesia. J NEURAL TRANSM , 109 (9) 1189 - 1194. 10.1007/s00702-002-0750-3.

Spacey, SD and Valente, EM and Wali, GM and Warner, TT and Jarman, PR and Schapira, AHV and Dixon, PH and Davis, MB and Bhatia, KP and Wood, NW (2002) Genetic and clinical heterogeneity in paroxysmal kinesigenic dyskinesia: Evidence for a third EKD gene. MOVEMENT DISORD , 17 (4) 717 - 725. 10.1002/mds.10126.

Valente, EM and Brancati, F and Caputo, V and Graham, EA and Davis, MB and Ferraris, A and Breteler, MMB and Gasser, T and Bonifati, V and Bentivoglio, AR and De Michele, G and Durr, A and Cortelli, P and Filla, A and Meco, G and Oostra, BA and Brice, A and Albanese, A and Dallapiccola, B and Wood, NW and European Consortium Genetic Suscep, (2002) PARK6 is a common cause of familial parkinsonism. NEUROLOGICAL SCIENCES , 23 S117 - S118.

Valente, EM and Brancati, F and Ferraris, A and Graham, EA and Davis, MB and Breteler, MMB and Gasser, T and Bonifati, V and Bentivoglio, AR and De Michele, G and Durr, A and Cortelli, P and Wassilowsky, D and Harhangi, BS and Rawal, N and Caputo, V and Filla, A and Meco, G and Oostra, BA and Brice, A and Albanese, A and Dallapiccola, B and Wood, NW and European Consortium Genetic Suscep, (2002) PARK6-linked parkinsonism occurs in several European families. ANN NEUROL , 51 (1) 14 - 18. 10.1002/ana.10053.

Warren, JD and Mummery, CJ and Al-Din, AS and Brown, P and Wood, NW (2002) Corticobasal degeneration syndrome with basal ganglia calcification: Fahr's disease as a corticobasal look-alike? MOVEMENT DISORD , 17 (3) 563 - 567. 10.1002/mds.10122.

West, A and Periquet, M and Lincoln, S and Lucking, CB and Nicholl, D and Bonifati, V and Rawal, N and Gasser, T and Lohmann, E and Deleuze, JF and Maraganore, D and Levey, A and Wood, N and Durr, A and Hardy, J and Brice, A and Farrer, M and French Parkinsons Dis Genetics Stu, and European Consortium Genetic Suscep, (2002) Complex relationship between parkin mutations and Parkinson disease. AM J MED GENET , 114 (5) 584 - 591. 10.1002/ajmg.10525.

2001

Bandopadhyay, R and de Silva, R and Khan, N and Graham, E and Vaughan, J and Engelender, S and Ross, C and Morris, H and Morris, C and Wood, NW and Daniel, S and Lees, A (2001) No pathogenic mutations in the synphilin-1 gene in Parkinson's disease. NEUROSCI LETT , 307 (2) 125 - 127.

Bird, TD and Jarvik, GP and Wood, NW (2001) Genetic association studies - Genes in search of diseases. NEUROLOGY , 57 (7) 1153 - 1154.

Bonifati, V and De Michele, G and Lucking, CB and Durr, A and Fabrizio, E and Ambrosio, G and Vanacore, N and De Mari, M and Marconi, R and Capus, L and Breteler, MMB and Gasser, T and Oostra, B and Wood, N and Agid, Y and Filla, A and Meco, G and Brice, A and Italian PD Genetics Study Grp, and French PD Genetics Study Grp, and European Consortium Genetic Suscep, (2001) The parkin gene and its phenotype. NEUROLOGICAL SCIENCES , 22 (1) 51 - 52.

Davenport, WJ and Siegel, AM and Dichgans, J and Drigo, P and Mammi, I and Pereda, P and Wood, NW and Rouleau, GA (2001) CCM1 gene mutations in families segregating cerebral cavernous malformations. NEUROLOGY , 56 (4) 540 - 543.

de Silva, R and Weiler, M and Morris, HR and Martin, ER and Wood, NW and Lees, AJ (2001) Strong association of a novel Tau promoter haplotype in progressive supranuclear palsy. NEUROSCI LETT , 311 (3) 145 - 148.

Frangione, B and Revesz, T and Vidal, R and Holton, J and Lashley, T and Houlden, H and Wood, N and Rostagno, A and Plant, G and Ghiso, J (2001) Familial cerebral amyloid angiopathy related to stroke and dementia. AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS , 8 36 - 42.

Gaspar, C and Lopes-Cendes, I and Hayes, S and Goto, J and Arvidsson, K and Dias, A and Silveira, I and Maciel, P and Coutinho, P and Lima, M and Zhou, YX and Soong, BW and Watanabe, M and Giunti, P and Stevanin, G and Riess, O and Sasaki, H and Hsieh, M and Nicholson, GA and Brunt, E and Higgins, JJ and Lauritzen, M and Tranebjaerg, L and Volpini, V and Wood, N and Ranum, L and Tsuji, S and Brice, A and Sequeiros, J and Rouleau, GA (2001) Ancestral origins of the Machado-Joseph disease mutation: A worldwide haplotype study. AM J HUM GENET , 68 (2) 523 - 528.

Gasser, T and Dichgans, M and Finsterer, J and Hausmanowa-Petrusewicz, I and Jurkat-Rott, K and Klopstock, T and Leguern, E and Lehesjoki, AE and Lehmann-Horn, F and Lynch, T and Morris, H and Rossor, M and Steinlein, OK and Wood, N and Zaremba, J and Zeviani, M and Zoharn, A and EFNS Task Force on Molecular Diagnosis of Neurologic Disorders, (2001) EFNS Task Force on Molecular Diagnosis of Neurologic Disorders: guidelines for the molecular diagnosis of inherited neurologic diseases. Second of two parts. Eur J Neurol , 8 (5) 407 - 424.

Gasser, T and Dichgans, M and Finsterer, J and Hausmanowa-Petrusewicz, I and Jurkat-Rott, K and Klopstock, T and LeGuern, E and Lehesjoki, AE and Lehmann-Horn, F and Lynch, T and Morris, H and Rossor, M and Steinlein, OK and Wood, N and Zaremba, J and Zeviani, M and Zoharn, A and EFNS Task Force on Molecular Diagnosis of Neurologic Disorders, (2001) EFNS Task Force on Molecular Diagnosis of Neurologic Disorders: guidelines for the molecular diagnosis of inherited neurologic diseases. First of two parts. Eur J Neurol , 8 (4) 299 - 314.

Ghiso, J and Revesz, T and Holton, J and Rostagno, A and Lashley, T and Houlden, H and Gibb, G and Anderton, B and Bek, T and Bojsen-Moller, M and Wood, N and Vidal, R and Braenagaard, H and Plant, G and Frangione, B (2001) Review - Chromosome 13 dementia syndromes as models of neurodegeneration. AMYLOID , 8 (4) 277 - 284.

Ghiso, JA and Holton, J and Miravalle, L and Calero, M and Lashley, T and Vidal, R and Houlden, H and Wood, N and Neubert, TA and Rostagno, A and Plant, G and Revesz, T and Frangione, B (2001) Systemic amyloid deposits in familial British dementia. J BIOL CHEM , 276 (47) 43909 - 43914.
An open access publication

Holton, JL and Ghiso, J and Lashley, T and Rostagno, A and Guerin, CJ and Gibb, G and Houlden, H and Ayling, H and Martinian, L and Anderton, BH and Wood, NW and Vidal, R and Plant, G and Frangione, B and Revesz, T (2001) Regional distribution of amyloid-Bri deposition and its association with neurofibrillary degeneration in familial British dementia. AM J PATHOL , 158 (2) 515 - 526.

Houlden, H and Baker, M and Morris, HR and MacDonald, N and Pickering-Brown, S and Adamson, J and Lees, AJ and Rossor, MN and Quinn, NP and Kertesz, A and Khan, MN and Hardy, J and Lantos, PL and George-Hyslop, PS and Munoz, DG and Mann, D and Lang, AE and Bergeron, C and Bigio, EH and Litvan, I and Bhatia, KP and Dickson, D and Wood, NW and Hutton, M (2001) Corticobasal degeneration and progressive supranuclear palsy share a common tau haplotype. NEUROLOGY , 56 (12) 1702 - 1706.

Houlden, H and King, RHM and Hashemi-Nejad, A and Wood, NW and Mathias, CJ and Reilly, M and Thomas, PK (2001) A novel TRK A (NTRK1) mutation associated with hereditary sensory and autonomic neuropathy type V. ANN NEUROL , 49 (4) 521 - 525.

Houlden, H and King, RHM and Wood, NW and Thomas, PK and Reilly, MM (2001) Mutations in the 5 ' region of the myotubularin-related protein 2 (MTMR2) gene in autosomal recessive hereditary neuropathy with focally folded myelin. BRAIN , 124 907 - 915.

Houlden, H. and King, R.H.M. and Wood, N.W. and Thomas, P.K. and Reilly, M.M. (2001) Mutations in the 5' region of the myotubularin-related protein 2 (MTMR2) gene in autosomal recessive hereditary neuropathy with focally folded myelin. Brain , 124 (5) pp. 907-915. 10.1093/brain/124.5.907.

Khan, N and Graham, E and Dixon, P and Morris, C and Mander, A and Clayton, D and Vaughan, J and Quinn, N and Lees, A and Daniel, S and Wood, N and de Silva, R (2001) Parkinson's disease is not associated with combined alpha-synuclein/apolipoprotein E susceptibility genotype. ANN NEUROL , 49 (5) 665 - 668.

McEntagart, M and Norton, N and Williams, H and Teare, MD and Dunstan, M and Baker, P and Houlden, H and Reilly, M and Wood, N and Harper, PS and Futreal, PA and Williams, N and Rahman, N (2001) Localization of the gene for distal hereditary motor neuronopathy VII (dHMN-VII) to chromosome 2q14. AM J HUM GENET , 68 (5) 1270 - 1276.

McEntagart, M. and Norton, N. and Williams, H. and Teare, M.D. and Dunstan, M. and Baker, P. and Houlden, H. and Reilly, M. and Wood, N. and Harper, P.S. and Futreal, P.A. and Williams, N. and Rahman, N. (2001) Localization of the gene for distal hereditary motor neuronopathy VII (dHMN-VII) to chromosome 2q14. The American Journal of Human Genetics , 68 (5) pp. 1270-1276. 10.1086/320122.

Mead, SH and Proukakis, C and Wood, N and Crosby, AH and Plant, GT and Warner, TT (2001) A large family with hereditary spastic paraparesis due to a frame shift mutation of the spastin (SPG4) gene: association with multiple sclerosis in two affected siblings and epilepsy in other affected family members. J NEUROL NEUROSUR PS , 71 (6) 788 - 791.

Morris, HR and Al-Sarraj, S and Schwab, C and Gwinn-Hardy, K and Perez-Tur, J and Wood, NW and Hardy, J and Lees, AJ and McGeer, PL and Daniel, SE and Steele, JC (2001) A clinical and pathological study of motor neurone disease on Guam. BRAIN , 124 2215 - 2222.

Morris, HR and Khan, MN and Janssen, JC and Brown, JM and Perez-Tur, J and Baker, M and Ozansoy, M and Hardy, J and Hutton, M and Wood, NW and Lees, AJ and Revesz, T and Lantos, P and Rossor, MN (2001) The genetic and pathological classification of familial frontotemporal dementia. ARCH NEUROL-CHICAGO , 58 (11) 1813 - 1816.

Morris, HR and Schrag, A and Nath, U and Burn, D and Quinn, NP and Daniel, S and Wood, NW and Lees, AJ (2001) Effect of ApoE and tau on age of onset of progressive supranuclear palsy and multiple system atrophy. NEUROSCI LETT , 312 (2) 118 - 120.

Nardocci, N and Fernandez-Alvarez, E and Wood, NW and Spacey, SD and Richter, A (2001) The paroxysmal dyskinesias. In: Guerrini, R and Aicardi, J and Andermann, F and Hallett, M, (eds.) Epilepsy and movement disorders. (125 - 139). Cambridge University Press: Cambridge.

Nath, U and Ben-Shlomo, Y and Thomson, RG and Morris, HR and Wood, NW and Lees, AJ and Burn, DJ (2001) The prevalence of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome) in the UK. BRAIN , 124 1438 - 1449.

Patel, H and Hart, PE and Warner, T and Allen, I and Phillimore, HE and Silver, JR and Wood, NW and Jeffery, S and Patton, MA and Crosby, AH (2001) Silver syndrome is not linked to any of the previously established autosomal dominant hereditary spastic paraplegia loci. AM J MED GENET , 102 (1) 68 - 72.

Periquet, M and Lucking, CB and Vaughan, JR and Bonifati, V and Durr, A and De Michele, G and Horstink, MW and Farrer, M and Illarioshkin, SN and Pollak, P and Borg, M and Brefel-Courbon, C and Denefle, P and Meco, G and Gasser, T and Breteler, MMB and Wood, NW and Agid, Y and Brice, A and French Parkinsons Dis Genetics Stu, and European Consortium Genetic Suscep, (2001) Origin of the mutations in the parkin gene in europe: Exon rearrangements are independent recurrent events, whereas point mutations may result from founder effects. AM J HUM GENET , 68 (3) 617 - 626.

Placzek, MR and Misbahuddin, A and Chaudhuri, KR and Wood, NW and Bhatia, KP and Warner, TT (2001) Cervical dystonia is associated with a polymorphism in the dopamine (D5) receptor gene. J NEUROL NEUROSUR PS , 71 (2) 262 - 264.

Rampoldi, L and Dobson-Stone, C and Rubio, JP and Danek, A and Chalmers, RM and Wood, NW and Verellen, C and Ferrer, X and Malandrini, A and Fabrizi, GM and Brown, R and Vance, J and Pericak-Vance, M and Rudolf, G and Carre, S and Alonso, E and Manfredi, M and Nemeth, AH and Monaco, AP (2001) A conserved sorting-associated protein is mutant in chorea- acanthocytosis. Nature Genetics , 28 (2) 119 - 120.

Reilly, MM and Lee, MJ and Sweeney, MG and Stephenson, D and Davis, M and Groves, M and Houlden, H and Wood, NW and Scaravilli, F (2001) Genetic analysis of the mutilated foot (mf) rat: an animal model for human hereditary sensory neuropathy. AM J HUM GENET , 69 (4) 501 - 501.

Sheen, VL and Dixon, PH and Fox, JW and Hong, SE and Kinton, L and Sisodiya, SM and Duncan, JS and Dubeau, F and Scheffer, IE and Schachter, SC and Wilner, A and Henchy, R and Crino, P and Kamuro, K and DiMario, F and Berg, M and Kuzniecky, R and Cole, AJ and Bromfield, E and Biber, M and Schomer, D and Wheless, J and Silver, K and Mochida, GH and Berkovic, SF and Andermann, F and Andermann, E and Dobyns, WB and Wood, NW and Walsh, CA (2001) Mutations in the X-linked filamin 1 gene cause periventricular nodular heterotopia in males as well as in females. HUM MOL GENET , 10 (17) 1775 - 1783.

Valente, EM and Bentivoglio, AR and Cassetta, E and Dixon, PH and Davis, MB and Ferraris, A and Ialongo, T and Frontali, M and Wood, NW and Albanese, A (2001) DYT13, a novel primary torsion dystonia locus, maps to chromosome 1p36.13-36.32 in an Italian family with cranial cervical or upper limb onset. ANN NEUROL , 49 (3) 362 - 366.

Valente, EM and Bentivoglio, AR and Cassetta, E and Dixon, PH and Davis, MB and Ferraris, A and Ialongo, T and Frontali, M and Wood, NW and Albanese, A (2001) Identification of a novel primary torsion dystonia loons (DYT13) on chromosome 1p36 in an Italian family with cranial-cervical or upper limb onset. NEUROLOGICAL SCIENCES , 22 (1) 95 - 96.

Valente, EM and Bentivoglio, AR and Dixon, PH and Ferraris, A and Ialongo, T and Frontali, M and Albanese, A and Wood, NW (2001) Localization of a novel locus for autosomal recessive early-onset parkinsonism, PARK6, on human chromosome 1p35-p36. AM J HUM GENET , 68 (4) 895 - 900.

Valente, EM and Brancati, F and Ferraris, A and Bentivoglio, AR and Bonifati, V and Vaughan, J and Pizzuti, A and De Michele, G and Caputo, V and Brice, A and Gasser, T and Breteler, M and Oostra, BA and Dallapiccola, B and Wood, NW and European Consortium Genet Suscepti, (2001) PARK6 is a major locus in early-onset parkinsonism. AM J HUM GENET , 69 (4) 500 - 500.

Vaughan, JR and Davis, MB and Wood, NW (2001) Genetics of Parkinsonism: a review. ANN HUM GENET , 65 111 - 126.

Wood, NW and Kinton, L and Hanna, MG (2001) Genetics of the overlap between epilepsy and movement disorders. In: Guerrini, R and Aicardi, J and Andermann, F and Hallett, M, (eds.) Epilepsy and movement disorders. (451 - 464). Cambridge University Press: Cambridge.

Worth, PF and Wood, NW (2001) Spinocerebellar ataxia type 12 is rare in the United Kingdom. NEUROLOGY , 56 (3) 419 - 420.

Worth, PF and Wood, NW (2001) Genotype to phenotype in the spinocerebellar ataxias. In: Malcom, S and Goodship, J, (eds.) Genotype to phenotype. (165 - 187). Bios Scientific Publishers

2000

Bandmann, O and Vaughan, JR and Holmans, P and Marsden, CD and Wood, NW (2000) Detailed genotyping demonstrates association between the slow acetylator genotype for N-acetyltransferase 2 (NAT2) and familial Parkinson's disease. MOVEMENT DISORD , 15 (1) 30 - 35.

de Silva, HA and Khan, NL and Wood, NW (2000) The genetics of Parkinson's disease. CURR OPIN GENET DEV , 10 (3) 292 - 298.

Houlden, H and Baker, M and McGowan, E and Lewis, P and Hutton, M and Crook, R and Wood, NW and Kumar-Singh, S and Geddes, J and Swash, M and Scaravilli, F and Holton, JL and Lashley, T and Tomita, T and Hashimoto, T and Verkkoniemi, A and Kalimo, H and Somer, M and Paetau, A and Martin, JJ and Van Broeckhoven, C and Golde, T and Hardy, J and Haltia, M and Revesz, T (2000) Variant Alzheimer's disease with spastic paraparesis and cotton wool plaques is caused by PS-1 mutations that lead to exceptionally high amyloid-beta concentrations. ANN NEUROL , 48 (5) 806 - 808.

Jarman, PR and Bhatia, KP and Davie, C and Heales, SJR and Turjanski, N and Taylor-Robinson, SD and Marsden, CD and Wood, NW (2000) Paroxysmal dystonic choreoathetosis: Clinical features and investigation of pathophysiology in a large family. MOVEMENT DISORD , 15 (4) 648 - 657.

Lodi, R and Schapira, AHV and Manners, D and Styles, P and Wood, NW and Taylor, DJ and Warner, TT (2000) Abnormal in vivo skeletal muscle energy metabolism in Huntington's disease and dentatorubropallidoluysian atrophy. ANN NEUROL , 48 (1) 72 - 76.

Lucking, CB and Durr, A and Bonifati, V and Vaughan, J and De Michele, G and Gasser, T and Harhangi, BS and Meco, G and Denefle, P and Wood, NW and Agid, Y and Brice, A and European Consortium Genetic Suscep, and French Parkinsons Dis Genetics Stu, (2000) Association between early-onset Parkinson's disease and mutations in the parkin gene. NEW ENGL J MED , 342 (21) 1560 - 1567.

Morris, HR and Vaughan, JR and Datta, SR and Bandopadhyay, R and de Silva, HAR and Schrag, A and Cairns, NJ and Burn, D and Nath, U and Lantos, PL and Daniel, S and Lees, AJ and Quinn, NP and Wood, NW (2000) Multiple system atrophy/progressive supranuclear palsy: alpha-Synuclein, synphilin, tau, and APOE. NEUROLOGY , 55 (12) 1918 - 1920.

Munchau, A and Valente, EM and Davis, MB and Stinton, V and Wood, NW and Quinn, NP and Bhatia, KP (2000) A Yorkshire family with adult-onset cranio-cervical primary torsion dystonia. MOVEMENT DISORD , 15 (5) 954 - 959.

Munchau, A and Valente, EM and Shahidi, GA and Eunson, LH and Hanna, RG and Quinn, NP and Schapira, AHV and Wood, NW and Bhatia, KP (2000) A new family with paroxysmal exercise induced dystonia and migraine: a clinical and genetic study. J NEUROL NEUROSUR PS , 68 (5) 609 - 614.

Spauschus, A and Rea, R and Eunson, L and Wood, NW and Hanna, MG and Kullmann, DM (2000) Functional characterisation of mutant Kv1.1 subunits from two families with episodic ataxia type 1. J PHYSIOL-LONDON , 523 156P - 157P.

Valente, EM and Spacey, SD and Wali, GM and Bhatia, KP and Dixon, PH and Wood, NW and Davis, MB (2000) A second paroxysmal kinesigenic choreoathetosis locus (EKD2) mapping on 16q13-q22.1 indicates a family of genes which give rise to paroxysmal disorders on human chromosome 16. BRAIN , 123 2040 - 2045.

Weiler, M and de Silva, HAR and Morris, H and Wood, NW and Lees, AJ (2000) Strong association of novel tau promoter polymorphisms with progressive supranuclear palsy. AM J HUM GENET , 67 (4) 193 - 193.

Wilson, CJ and Wood, NW and Leonard, JV and Surtees, R and Rahman, S (2000) Mitochondrial DNA point mutation T9176C in Leigh syndrome. J CHILD NEUROL , 15 (12) 830 - 833.

Wood, NW and Harding, AE (2000) Ataxic disorders. In: Bradley, WG and Daroff, RB and Fenichel, GM and Marsden, CD, (eds.) Neurology in clinical practice: volume 1. Principles of diagnosis and management. (309 - 317). Butterworth Heinemann: Oxford.

Wood, NW and Harding, AE (2000) Cerebellar and spinocerebellar disorders. In: Bradley, WG and Daroff, RB and Fenichel, GM and Marsden, CD, (eds.) Neurology in clinical practice: volume 2. The neurological disorders. (1931 - 1951). Butterworth Heinemann: Oxford.

Worth, PF and Houlden, H and Giunti, P and Davis, MB and Wood, NW (2000) Large, expanded repeats in SCA8 are not confined to patients with cerebellar ataxia. NAT GENET , 24 (3) 214 - 215.

Zhang, J and Hattori, N and Leroy, E and Morris, HR and Kubo, SI and Kobayashi, T and Wood, NW and Polymeropoulos, MH and Mizuno, Y (2000) Association between a polymorphism of ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) gene and sporadic Parkinson's disease. PARKINSONISM RELAT D , 6 (4) 195 - 197.

1999

Abbas, N and Lucking, CB and Ricard, S and Durr, A and Bonifati, V and De Michele, G and Bouley, S and Vaughan, JR and Gasser, T and Marconi, R and Broussolle, E and Brefel-Courbon, C and Harhangi, BS and Oostra, AB and Fabrizio, E and Bohme, GA and Pradier, L and Wood, NW and Filla, A and Meco, G and Denefle, P and Agid, Y and Brice, A and French Parkinson's Dis Genetics Study Grp, and European Consortium Genetic Susceptibility Park, (1999) A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe. HUM MOL GENET , 8 (4) 567 - 574.

Andrews, TC and Weeks, RA and Turjanski, N and Gunn, RN and Watkins, LHA and Sahakian, B and Hodges, JR and Rosser, AE and Wood, NW and Brooks, DJ (1999) Huntington's disease progression PET and clinical observations. BRAIN , 122 2353 - 2363.

Bandmann, O and Vaughan, J and Holmans, PA and Marsden, CD and Wood, NW (1999) Toxins, genetics, and Parkinson's disease: the role of N-acetyltransferase 2. In: UNSPECIFIED (199 - 204).

Chalmers, RM and Andreae, L and Wood, NW and Raj, RVKD and Casey, ATH (1999) Familial hydrocephalus. J NEUROL NEUROSUR PS , 67 (3) 410 - 411.

Clark, KM and Taylor, RW and Johnson, MA and Chinnery, PF and Chrzanowska-Lightowlers, ZMA and Andrews, RM and Nelson, IP and Wood, NW and Lamont, PJ and Hanna, MG and Lightowlers, RN and Turnbull, DM (1999) An mtDNA mutation in the initiation codon of the cytochrome C oxidase subunit II gene results in lower levels of the protein and a mitochondrial encephalomyopathy. AMERICAN JOURNAL OF HUMAN GENETICS , 64 (5) 1330 - 1339. 10.1086/302361.

Dixon, PH and Stinton, VJ and Humphray, SJ and Hammond, S and Howard, PJ and Dunham, I and Wood, N and Davis, MB (1999) Physical and EST mapping on chromosome 9: Candidate Genes for the geniospasm (GSM1) locus. AM J HUM GENET , 65 (4) A224 - A224.

Elliott, PM and Hanna, MG and Ward, SA and Chinnery, PF and Turnbull, DM and Wood, NW and McKenna, WJ (1999) Diagnostic utility of metabolic exercise testing in a patient with cardiovascular disease. HEART , 81 (4) 441 - 443.

Eunson, LH and Davis, MB and Wood, NW and Hanna, MG (1999) The national DNA-based diagnostic service for periodic paralyses. J MED GENET , 36 S63 - S63.

Eunson, LH and Jouvenceau, A and Ramesh, V and Zuberi, SM and Nairne, A and Hyman, N and Wood, NW and Spauschus, A and Kullmann, DM and Hanna, MG (1999) New mutations in the voltage-gated calcium channel gene CACNA1A in british families with episodic ataxia type 2. AM J HUM GENET , 65 (4) A293 - A293.

Flowers, JM and Leigh, PN and Davies, AM and Ninkina, NN and Buchman, VL and Vaughan, J and Wood, NW and Powell, JF (1999) Mutations in the gene encoding human persyn are not associated with amyotrophic lateral sclerosis or familial Parkinson's disease. Neuroscience Letters , 274 (1) 21 - 24.

Giunti, P and Stevanin, G and Worth, PF and David, G and Brice, A and Wood, NW (1999) Molecular and clinical study of 18 families with ADCA type II: Evidence for genetic heterogeneity and De Novo mutation. AM J HUM GENET , 64 (6) 1594 - 1603.

Harhangi, BS and Farrer, MJ and Lincoln, S and Bonifati, V and Meco, G and De Michele, G and Brice, A and Durr, A and Martinez, M and Gasser, T and Bereznai, B and Vaughan, JR and Wood, NW and Hardy, J and Oostra, BA and Breteler, MMB (1999) The lle93Met mutation in the ubiquitin carboxy-terminal-hydrolase-L1 gene is not observed in European cases with familial Parkinson's disease. NEUROSCI LETT , 270 (1) 1 - 4.

Jarman, P and Wood, N (1999) Parkinson's disease genetics comes of age - Knowledge about genes in familial parkinsonism helps elucidate idiopathic disease. BRIT MED J , 318 (7199) 1641 - 1642.

Jarman, PR and del Grosso, N and Valente, EM and Leube, B and Cassetta, E and Bentivoglio, AR and Waddy, HM and Uitti, RJ and Maraganore, DM and Albanese, A and Frontali, M and Auburger, G and Bressman, SB and Wood, NW and Nygaard, TG (1999) Primary torsion dystonia: the search for genes is not over. J NEUROL NEUROSUR PS , 67 (3) 395 - 397.

Khan, NL and Wood, NW (1999) Prader-Willi and Angelman syndromes: update on genetic mechanisms and diagnostic complexities. Curr Opin Neurol , 12 (2) 149 - 154.

Lincoln, S and Vaughan, J and Wood, N and Baker, M and Adamson, J and Gwinn-Hardy, K and Lynch, T and Hardy, J and Farrer, M (1999) Low frequency of pathogenic mutations in the ubiquitin carboxyterminal hydrolase gene in familial Parkinson's disease. NEUROREPORT , 10 (2) 427 - 429.

Marques, W and Hanna, MG and Marques, SR and Sweeney, MG and Thomas, PK and Wood, NW (1999) Phenotypic variation of a new P0 mutation in genetically identical twins. J NEUROL , 246 (7) 596 - 599.

Marques, W and Sweeney, MG and Wood, NW and Wroe, SJ and Marques, W (1999) Central nervous system involvement in a novel connexin 32 mutation affecting identical twins. J NEUROL NEUROSUR PS , 66 (6) 803 - 804.

Morris, HR and Baker, M and Lees, AJ and Hutton, M and Hardy, J and Wood, NW (1999) Further analysis of the association of tau with progressive supranuclear palsy. AM J HUM GENET , 65 (4) A462 - A462.

Morris, HR and Baker, M and Lees, AJ and Hutton, M and Hardy, J and Wood, NW (1999) Further analysis of the association of tau with progressive supranuclear palsy. The American Journal of Human Genetics , 65 2621 - ?.

Morris, HR and Janssen, JC and Bandmann, O and Daniel, SE and Rossor, MN and Lees, AJ and Wood, NW (1999) The tau gene A0 polymorphism in progressive supranuclear palsy and related neurodegenerative diseases. J NEUROL NEUROSUR PS , 66 (5) 665 - 667.

Morris, HR and Lees, AJ and Wood, NW (1999) Neurofibrillary tangle parkinsonian disorders - Tau pathology and tau genetics. MOVEMENT DISORD , 14 (5) 731 - 736.

Morris, HR and Perez-Tur, J and Janssen, JC and Brown, J and Lees, AJ and Wood, NW and Hardy, J and Hutton, M and Rossor, MN (1999) Mutation in the tau exon 10 splice site region in familiar frontotemporal dementia. ANN NEUROL , 45 (2) 270 - 271.

Morris, HR and Wood, NW and Lees, AJ (1999) Progressive supranuclear palsy (Steele-Richardson-Olszewski disease). POSTGRAD MED J , 75 (888) 579 - 584.

Pulkes, T and Eunson, L and Patterson, V and Siddiqui, A and Wood, NW and Nelson, IP and Morgan-Hughes, JA and Hanna, MG (1999) The mitochondrial DNA G13513A transition in ND5 is associated with a LHON/MELAS overlap syndrome and may be a frequent cause of MELAS. ANN NEUROL , 46 (6) 916 - 919.

Robinson, R and McCarthy, GT and Bandmann, O and Dobbie, M and Surtees, R and Wood, NW (1999) GTP cyclohydrolase deficiency; intrafamilial variation in clinical phenotype, including levodopa responsiveness. J NEUROL NEUROSUR PS , 66 (1) 86 - 89.

Robinson, RO and McCarthy, GT and Bandmann, O and Dobbie, M and Surtees, R and Wood, NW (1999) GTP cyclohydrolase deficiency: intrafamilial variation in phenotype, including levadopa responsiveness. Journal of Neurology, Neurosurgery and Psychiatry , 66 86 - 89.

Rojo, A and Pernaute, RS and Fontan, A and Ruiz, PG and Honnorat, J and Lynch, T and Chin, S and Gonzalo, I and Rabano, A and Martinez, A and Daniel, S and Pramsteller, P and Morris, H and Wood, N and Lees, A and Tabernero, C and Nyggard, T and Jackson, AC and Hanson, A and de Yebenes, JG (1999) Clinical genetics of familial progressive supranuclear palsy. BRAIN , 122 1233 - 1245.

Spacey, SD and Wood, NW (1999) The genetics of Parkinson's disease. CURR OPIN NEUROL , 12 (4) 427 - 432.

Sweeney, MG and Giunti, P and Stinton, VJ and Worth, PF and Hanna, MG and Wood, NW and Davis, MB (1999) Population genetics of the SCA6 locus in British families with ADCA. AM J HUM GENET , 65 (4) A400 - A400.

Valente, EM and Povey, S and Warner, TT and Wood, NW and Davis, MB (1999) Detailed haplotype analysis in Ashkenazi Jewish and non-Jewish British dystonic patients carrying the GAG deletion in the DYT1 gene: evidence for a limited number of founder mutations. ANN HUM GENET , 63 1 - 8.

Valente, EM and Povey, S and Warner, TT and Wood, NW and Davis, MB (1999) Detailed haplotype analysis in Ashkenazi Jewish and non-Jewish British dystonic patients carrying the GAG deletion in the DYT1 gene: Evidence for a limited number of founder mutations. Annals of Human Genetics , 63 (1) 1 - 8.

Valente, EM and Povey, S and Warner, TT and Wood, NW and Davis, MB (1999) Detailed haplotype analysis in Ashkenazi Jews and non-Jewish British dystonic patients carrying the GAG deletion in the DYT1 gene: evidence of two new founder mutations. Annals of Human Genetics , 63 1 - 8.

Vaughan, JR and Farrer, M and De Michele, G and Volpe, G and Hardy, J and Wood, NW (1999) Further evidence for a chromosome 4p haplotype segregating with Parkinson's disease in an independent Italian kindred. AM J HUM GENET , 65 (4) A496 - A496.

Worth, PF and Dunne, E and Nemeth, AH and Wood, NW (1999) Autosomal dominant cerebellar ataxia type III: No evidence for a large pathological CAG repeat expansion in the SCA 11 gene. AM J HUM GENET , 65 (4) A499 - A499.

Worth, PF and Giunti, P and Gardner-Thorpe, C and Dixon, PH and Davis, MB and Wood, NW (1999) Autosomal dominant cerebellar ataxia type III: Linkage in a large British family to a 7.6-cM region on chromosome 15q14-21.3. AM J HUM GENET , 65 (2) 420 - 426.

Zuberi, SM and Eunson, LH and Spauschus, A and De Silva, R and Tolmie, J and Wood, NW and McWilliam, RC and Stephenson, JPB and Kullmann, DM and Hanna, MG (1999) A novel mutation in the human voltage-gated potassium channel gene (Kv1.1) associates with episodic ataxia type 1 and sometimes with partial epilepsy. BRAIN , 122 817 - 825.

1998

Bandmann, O and Marsden, CD and Wood, NW (1998) Genetic aspects of Parkinson's disease. MOVEMENT DISORD , 13 (2) 203 - 211.

Bandmann, O and Marsden, CD and Wood, NW (1998) Atypical presentations of dopa-responsive dystonia. Adv Neurol , 78 283 - 290.

Bandmann, O and Valente, EM and Holmans, P and Surtees, RAH and Walters, JH and Wevers, RA and Marsden, CD and Wood, NW (1998) Dopa-responsive dystonia: A clinical and molecular genetic study. ANN NEUROL , 44 (4) 649 - 656.

Bandmann, O and Wood, NW (1998) Acetylator genotype and Parkinson's disease - Reply. LANCET , 351 (9096) 142 - 142.

Giunti, P and Sabbadini, G and Sweeney, MG and Davis, MB and Veneziano, L and Mantuano, E and Federico, A and Plasmati, R and Frontali, M and Wood, NW (1998) The role of the SCA2 trinucleotide repeat expansion in 89 autosomal dominant cerebellar ataxia families - Frequency, clinical and genetic correlates. BRAIN , 121 459 - 467.

Hanna, MG and Davis, MB and Sweeney, MG and Noursadeghi, M and Ellis, CJ and Elliot, P and Wood, NW and Marsden, CD (1998) Generalized chorea in two patients harboring the Friedreich's ataxia gene trinucleotide repeat expansion. MOVEMENT DISORD , 13 (2) 339 - 340.

Hanna, MG and Nelson, IP and Morgan-Hughes, JA and Wood, NW (1998) MELAS: a new disease associated mitochondrial DNA mutation and evidence for further genetic heterogeneity. J NEUROL NEUROSUR PS , 65 (4) 512 - 517.

Hanna, MG and Nelson, IP and Rahman, S and Lane, RJM and Land, J and Heales, S and Cooper, MJ and Schapira, AHV and Morgan-Hughes, JA and Wood, NW (1998) Cytochrome c oxidase deficiency associated with the first stop-codon point mutation in human mtDNA. AM J HUM GENET , 63 (1) 29 - 36.

Hanna, MG and Stewart, J and Schapira, AHV and Wood, NW and Morgan-Hughes, JA and Murray, NMF (1998) Salbutamol treatment in a patient with hyperkalaemic periodic paralysis due to a mutation in the skeletal muscle sodium channel gene (SCN4A). J NEUROL NEUROSUR PS , 65 (2) 248 - 250.

Hanna, MG and Wood, N and Kullmann, DM (1998) Ion channels and neurological disease: DNA based diagnosis is now possible, and ion channels may be important in common paroxysmal disorders. J NEUROL NEUROSUR PS , 65 (4) 427 - 431.

Kapoor, R and Miller, DH and Jones, SJ and Plant, GT and Brusa, A and Gass, A and Hawkins, CP and Page, R and Wood, NW and Compston, DAS and Moseley, IF and McDonald, WI (1998) Effects of intravenous methylprednisolone on outcome in MRI-based prognostic subgroups in acute optic neuritis. NEUROLOGY , 50 (1) 230 - 237.

Lamont, PJ and Surtees, R and Woodward, CE and Leonard, JV and Wood, NW and Harding, AE (1998) Clinical and laboratory findings in referrals for mitochondrial DNA analysis. ARCH DIS CHILD , 79 (1) 22 - 27.

Lopes, J and Ravise, N and Vandenberghe, A and Palau, F and Ionasescu, V and Mayer, M and Levy, N and Wood, N and Tachi, N and Bouche, P and Latour, P and Ruberg, M and Brice, A and LeGuern, E (1998) Fine mapping of de novo CMT1A and HNPP rearrangements within CMT1A-REPs evidences two distinct sex-dependent mechanisms and candidate sequences involved in recombination. HUM MOL GENET , 7 (1) 141 - 148.

Lucking, CB and Abbas, N and Durr, A and Bonifati, V and Bonnet, AM and de Broucker, T and De Michele, G and Wood, NW and Agid, Y and Brice, A and European Consortium Genetic Susceptibility Park, and French Parkinsons Dis Genetics Study Grp, (1998) Homozygous deletions in parkin gene in European and North African families with autosomal recessive juvenile parkinsonism. LANCET , 352 (9137) 1355 - 1356.

Marques, W and Thomas, PK and Sweeney, MG and Carr, L and Wood, NW (1998) Dejerine-Sottas neuropathy and PMP22 point mutations: A new base pair substitution and a possible "hot spot" on Ser72. ANN NEUROL , 43 (5) 680 - 683.

Stevanin, G and Giunti, P and David, G and Belal, S and Durr, A and Ruberg, M and Wood, N and Brice, A (1998) De novo expansion of intermediate alleles in spinocerebellar ataxia 7. HUM MOL GENET , 7 (11) 1809 - 1813.

Valente, EM and Warner, TT and Jarman, PR and Mathen, D and Fletcher, NA and Marsden, CD and Bhatia, KP and Wood, NW (1998) The role of DYT1 in primary torsion dystonia in Europe. BRAIN , 121 2335 - 2339.

Vaughan, J and Durr, A and Tassin, J and Bereznai, B and Gasser, T and Bonifati, V and De Michele, G and Fabrizio, E and Volpe, G and Bandmann, O and Johnson, WG and Golbe, LI and Breteler, M and Meco, G and Agid, Y and Brice, A and Marsden, CD and Wood, NW (1998) The alpha-synuclein Ala53Thr mutation is not a common cause of familial Parkinson's disease: a study of 230 European cases. European Consortium on Genetic Susceptibility in Parkinson's Disease. Ann Neurol , 44 (2) 270 - 273. 10.1002/ana.410440221.

Vaughan, J and Durr, A and Tassin, J and Bereznai, B and Gasser, T and Bonifati, V and De Michele, G and Fabrizio, E and Volpe, G and Bandmann, O and Johnson, WG and Golbe, LI and Breteler, M and Meco, G and Agid, Y and Brice, A and Marsden, CD and Wood, NW and Eurpean Consortium Genetic Susceptibility Parki, (1998) The alpha-synuclein Ala53Thr mutation is not a common cause of familial Parkinson's disease: A study of 230 European cases. ANN NEUROL , 44 (2) 270 - 273.

Vaughan, JR and Farrer, MJ and Wszolek, ZK and Gasser, T and Durr, A and Agid, Y and Bonifati, V and DeMichele, G and Volpe, G and Lincoln, S and Breteler, M and Meco, G and Brice, A and Marsden, CD and Hardy, J and Wood, NW (1998) Sequencing of the alpha-synuclein gene in a large series of cases of familial Parkinson's disease fails to reveal any further mutations. HUM MOL GENET , 7 (4) 751 - 753.

Wood, NW (1998) Genetic risk factors in Parkinson's disease. ANNALS OF NEUROLOGY , 44 (3) S58 - S62.

Wood, NW (1998) Diagnosing Friedreich's ataxia. ARCH DIS CHILD , 78 (3) 204 - 207.

Wood, NW (1998) Genetic risk factors in Parkinson's disease. In: Olanow, CW and Jenner, P, (eds.) Beyond the decade of the brain: neuroprotection in Parkinson's disease. (115 - 120). Wells Medical: Tunbridge Wells.

1997

Bandmann, O and Marsden, CD and Wood, NW (1997) Atypical presentations of DRD mutations. Advances in Neurology

Bandmann, O and Sweeney, MG and Daniel, SE and Marsden, CD and Wood, NW (1997) Mitochondrial DNA polymorphisms in pathologically proven Parkinson's disease. J NEUROL , 244 (4) 262 - 265.

Bandmann, O and Sweeney, MG and Daniel, SE and Wenning, GK and Quinn, N and Marsden, CD and Wood, NW (1997) Multiple-system atrophy is genetically distinct from identified inherited causes of spinocerebellar degeneration. NEUROLOGY , 49 (6) 1598 - 1604.

Bandmann, O and Vaughan, J and Holmans, P and Marsden, CD and Wood, NW (1997) Association of slow acetylator genotype for N-acetyltransferase 2 with familial Parkinson's disease. LANCET , 350 (9085) 1136 - 1139.

Bandmann, O and Vaughan, J and Holmans, P and Marsden, CD and Wood, NW (1997) NAT2 slow acetylator phenotype is associated with familial Parkinson's disease. The Lancet , 350 1142 - 1145.

Bandmann, O and Vaughan, JR and Holmans, P and Marsden, CD and Wood, NW (1997) The role of NAT2 in Parkinson's disease. Advances in Neurology

Chalmers, RM and RiordanEva, P and Wood, NW (1997) Autosomal recessive inheritance of hereditary motor and sensory neuropathy with optic atrophy. J NEUROL NEUROSUR PS , 62 (4) 385 - 387.

David, G and Abbas, N and Stevanin, G and Durr, A and Yvert, G and Cancel, G and Weber, C and Imbert, G and Saudou, F and Antoniou, E and Drabkin, H and Gemmill, R and Giunti, P and Benomar, A and Wood, N and Ruberg, M and Agid, Y and Mandel, JL and Brice, A (1997) Cloning of the SCA7 gene reveals a highly unstable CAG repeat expansion. NAT GENET , 17 (1) 65 - 70.

Gasser, T and MullerMyhsok, B and Wszolek, ZK and Durr, A and Vaughan, JR and Bonifati, V and Meco, G and Bereznai, B and Oehlmann, R and Agid, Y and Brice, A and Wood, N (1997) Genetic complexity and Parkinson's disease. SCIENCE , 277 (5324) 388 - 389.

Giunti, P and Sweeney, MG and Davis, MB and Wood, NW (1997) Characterization of the SCA2 CAG repeat expansion in ADCA type I families. J MED GENET , 34 548 - 548.

Hanna, MG and Davis, MB and Sweeney, MG and Nousanjani, M and Ellis, C and Elliott, P and Wood, NW (1997) Generalised chorea in two patients harbouring Friedrich's ataxia trinucleotide repeat expansion. Movement Disorders

Jarman, PR and Bandmann, O and Marsen, CD and Wood, NW (1997) GTP cyclohydrolase I mutations in patients with dystonia responsive to anticholinergic drugs. J NEUROL NEUROSUR PS , 63 (3) 304 - 308.

Jarman, PR and Davis, MB and Hodgson, SV and Marsden, CD and Wood, NW (1997) Paroxysmal dystonic choreoathetosis - Genetic linkage studies in a British family. BRAIN , 120 2125 - 2130.

Jarman, PR and Wood, NW and Davis, MT and Davis, PV and Bhatia, KP and Marsden, CD and Davis, MB (1997) Hereditary geniospasm: Linkage to chromosome 9q13-q21 and evidence for genetic heterogeneity. AM J HUM GENET , 61 (4) 928 - 933.

Kellett, MW and Fletcher, NA and Wood, N and Enevoldson, TP (1997) Trinucleotide (GAA)n repeat expansion in two families with Friedreich's ataxia with retained reflexes. J NEUROL NEUROSUR PS , 63 (6) 780 - 783.

Kompoliti, K and Pappert, EJ and Goetz, CG and Ford, B and Wood, NW (1997) Progressive cognitive decline with truncal/limb ataxia and ballistic movements. MOVEMENT DISORD , 12 (6) 1075 - 1084.

Lamont, PJ and Davis, MB and Wood, NW (1997) Identification and sizing of the GAA trinucleotide repeat expansion of Friedreich's ataxia in 56 patients - Clinical and genetic correlates. BRAIN , 120 673 - 680.

Lodi, R and Taylor, DJ and Tabrizi, SJ and Kumar, S and Sweeney, M and Wood, NW and Styles, P and Radda, GK and Schapira, AHV (1997) In vivo skeletal muscle mitochondrial function in Leber's hereditary optic neuropathy assessed by P-31 magnetic resonance spectroscopy. ANN NEUROL , 42 (4) 573 - 579.

Lopes, J and Vandenberghe, A and Tardieu, S and Ionasecu, V and Levy, N and Wood, NW and Tachi, N and Bouche, P and Brice, A and Le Guern, E (1997) The 17p11.2 rearrangements resulting in CMT1A and HNPP are observed at different frequencies and occur by different sex-dependent mechanisms. Nature Genetics

Nelson, I and Hanna, MG and Wood, NW and Harding, AE (1997) Depletion of mitochondrial DNA by ddC in untransformed human cell lines. SOMAT CELL MOLEC GEN , 23 (4) 287 - 290.

Nelson, I and Hanna, MG and Wood, NW and Harding, AE (1997) Depletion of mitochondrial DNA by ddC in untransformed human cell lines. Somatic Cell and Molecular Genetics , 23 (4) 287 - 290.

Plante-Bordeneuve, V and Taussig, D and Thomas, F and Said, G and Wood, NW and Marsden, CD and Harding, AE (1997) Evaluation of four candidate genes encoding proteins of the dopamine pathway in familial and sporadic Parkinson's disease: evidence for association of a DRD2 allele. Neurology , 48 1589 - 1593.

Rubio, JP and Danek, A and Stone, C and Chalmers, R and Wood, N and Verellen, C and Ferrer, X and Malandrini, A and Fabrizi, GM and Manfredi, M and Vance, J and PericakVance, M and Brown, R and Rudolf, G and Picard, F and Alonso, E and Brin, M and Nemeth, AH and Farrall, M and Monaco, AP (1997) Chorea-acanthocytosis: Genetic linkage to chromosome 9q21. AM J HUM GENET , 61 (4) 899 - 908.

Wood, N (1997) Genes and parkinsonism. J NEUROL NEUROSUR PS , 62 (4) 305 - 309.

Wood, N (1997) Genetic aspects of parkinsonism. BAILLIERE CLIN NEUR , 6 (1) 37 - 53.

Wood, NW (1997) Diagnosing Friedreich's ataxia. Archives of Disease in Childhood

1996

Bandmann, O and Daniel, S and Marsden, CD and Wood, NW and Harding, AE (1996) The CTP-cyclohydrolase I gene in atypical Parkinsonian patients: A clinico-genetic study. J NEUROL SCI , 141 (1-2) 27 - 32.

Bandmann, O and Davis, MB and Marsden, CD and Wood, NW (1996) The human homologue of the weaver mouse gene in familial and sporadic Parkinson's disease. NEUROSCIENCE , 72 (4) 877 - 879.

Bandmann, O and Nygaard, TG and Surtees, R and Marsden, CD and Wood, NW and Harding, AE (1996) Dopa-responsive dystonia in British patients: New mutations of the GTP-cyclohydrolase I gene and evidence for genetic heterogeneity. HUM MOL GENET , 5 (3) 403 - 406.

Chalmers, RM and Davis, MB and Sweeney, MG and Wood, NW and Harding, AE (1996) Evidence against an X-linked visual loss susceptibility locus in Leber hereditary optic neuropathy. AM J HUM GENET , 59 (1) 103 - 108.

David, G and Abbas, N and Coullin, P and Stevanin, G and Horta, W and Gemmill, R and Weissenbach, J and Wood, N and Cunha, S and Drabkin, H and Harding, AE and Agid, Y and Brice, A (1996) The gene for autosomal dominant cerebellar ataxia type II is located in a 5-cM region in 3p12-p13: Genetic and physical mapping of the SCA7 locus. AM J HUM GENET , 59 (6) 1328 - 1336.

RiordanEva, P and Wood, NW (1996) Mitochondrial disorders in neuro-ophthalmology. CURR OPIN NEUROL , 9 (1) 1 - 4.

1995

COMPSTON, DAS and WOOD, HK and ROBERTSON, N and SAWCER, S and WOOD, NW (1995) GENES AND SUSCEPTIBILITY TO MULTIPLE-SCLEROSIS. ACTA NEUROLOGICA SCANDINAVICA , 91 43 - 51.

KELLARWOOD, HF and WOOD, NW and HOLMANS, P and CLAYTON, D and ROBERTSON, N and COMPSTON, DAS (1995) MULTIPLE-SCLEROSIS AND THE HLA-D REGION - LINKAGE AND ASSOCIATION STUDIES. J NEUROIMMUNOL , 58 (2) 183 - 190.

WOOD, NW and SAWCER, SJ and KELLARWOOD, HF and HOLMANS, P and CLAYTON, D and ROBERTSON, N and COMPSTON, DAS (1995) THE T-CELL RECEPTOR-BETA LOCUS AND SUSCEPTIBILITY TO MULTIPLE-SCLEROSIS. NEUROLOGY , 45 (10) 1859 - 1863.

WOOD, NW and SAWCER, SJ and KELLERWOOD, HF and HOLMANS, P and CLAYTON, D and ROBERTSON, N and COMPSTON, DAS (1995) SUSCEPTIBILITY TO MULTIPLE-SCLEROSIS AND THE IMMUNOGLOBULIN HEAVY-CHAIN VARIABLE REGION. J NEUROL , 242 (10) 677 - 682.

1994

EOLI, M and WOOD, NW and KELLARWOOD, HF and HOLMANS, P and CLAYTON, D and COMPSTON, DAS (1994) NO LINKAGE BETWEEN MULTIPLE-SCLEROSIS AND THE T-CELL RECEPTOR-ALPHA CHAIN LOCUS. J NEUROL SCI , 124 (1) 32 - 37.

MUMFORD, CJ and WOOD, NW and KELLARWOOD, H and THORPE, JW and MILLER, DH and COMPSTON, DAS (1994) THE BRITISH-ISLES SURVEY OF MULTIPLE-SCLEROSIS IN TWINS. NEUROLOGY , 44 (1) 11 - 15.

WOOD, NW and HOLMANS, P and CLAYTON, D and ROBERTSON, N and COMPSTON, DAS (1994) NO LINKAGE OR ASSOCIATION BETWEEN MULTIPLE-SCLEROSIS AND THE MYELIN BASIC-PROTEIN GENE IN AFFECTED SIBLING PAIRS. J NEUROL NEUROSUR PS , 57 (10) 1191 - 1194.

1992

MUMFORD, CJ and FRASER, MB and WOOD, NW and COMPSTON, DAS (1992) MULTIPLE-SCLEROSIS IN THE CAMBRIDGE HEALTH DISTRICT OF EAST-ANGLIA. J NEUROL NEUROSUR PS , 55 (10) 877 - 882.

NULL

Sebastian, CL and Roiser, JP and Tan, GCY and Viding, E and Wood, NW and Blakemore, SJ Effects of age and MAOA genotype on the neural processing of social rejection. Genes, Brain and Behavior 10.1111/j.1601-183X.2010.00596.x.

Tabrizi, SJ and Wood, NW Neurogenetics. In: Scadding, J and Losseff, N, (eds.) Clinical Neurology. Hodder Arnold

Wood, N and Guo, L and Cordeiro, MF Imaging human retinal ganglion cells. In: Grehn, F and Stamper, R, (eds.) Glaucoma. Springer Editions: Heidelberg/New York.

This list was generated on Thu May 23 03:14:01 2013 BST.

Page last modified on 20 mar 13 17:19

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