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chromosome 22q deletion

Parkinson's chromosome deletion linked to other genetic disorders

Researchers, led by BRC-supported Professor Nicholas Wood, UCL Institute of Neurology, have made a breakthrough in their understanding of Parkinson’s disease after they discovered a chromosome deletion linked to Parkinson’s disease and other genetic disorders. More...

Prof John Hardy

Prof John Hardy is the first UK winner of $3m Breakthrough Prize in Life Sciences

Professor John Hardy (UCL Institute of Neurology) has been awarded the $3 million Breakthrough Prize in Life Sciences for his pioneering research into the genetic causes of Alzheimer’s disease, other forms of dementia and Parkinson’s disease. More...

John Hardy, PhD, right, accepted the 2015 Robert A. Pritzker Prize from MJFF VP Brian Fiske, PhD, and Michael J. Fox on April 15.

John Hardy awarded 2015 Robert A. Pritzker Prize for Leadership in Parkinson's Research

One of the UK Parkinson's Disease Consortium Principal Investigators, Prof John Hardy, has been awarded the 2015 Robert A. Pritzker Prize for his leadership in Parkinson's genetics research. The award was presented by Michael J. Fox at a ceremony in New York on April 15. From the Michael J. Fox Foundation website: More...

Webcast - Prof Nicholas Wood - Advances in Genetic Understanding of Parkinson's Disease.

Video: Advances in Genetic Understanding of Parkinson's Disease

Webcast of the presentation entitled ‘Advances in Genetic Understanding of Parkinson's Disease’ given by Nicholas Wood (University College London, United Kingdom) presented at the Biochemical Society Hot Topic event, PINK1-Parkin Signalling in Parkinson’s Disease and Beyond, held in December 2014. More...

Pedigrees and I-FP-CIT SPECT scan images of the four families with GCH1 mutations involved in this study.

GCH1 gene and Parkinson's risk

A study published in Brain, led by researchers at UCL Institute of Neurology, has shown that genetic mutations which cause a decrease in dopamine production in the brain and lead to a form of childhood-onset Dystonia, also play a role in the development of Parkinson’s disease.
More...

Andrew Lees

(Co-Investigator)

Andrew Lees


Born on Merseyside Andrew Lees qualified in medicine at the Royal London Hospital Medical College in 1970. His postgraduate clinical training in neurology was undertaken at l’Hôpital de la Salpetrière, Paris, University College London Hospital and the National Hospital for Neurology and Neurosurgery.

At the age of thirty two he was appointed to the staff at the National, Middlesex, and Whittington Hospitals. He was appointed Professor of Neurology at the National Hospital for Neurology and Neurosurgery, Queen Square and succeeded Professor Michael Harrison as Director of the Reta Lila Weston Institute for Neurological Studies at UCL in 1998. He is also and Director of the Queen Square Brain Bank for Neurological Disorders and Sara Koe PSP Research Centres.

He is Chairman of the Medical Advisory Panel of the PSP Association and an advisor to the UK Medical Research Council.

He has achieved international recognition for his work in Parkinson’s disease and abnormal movement disorders and was elected President of the International Movement Disorder Society (2004-6). In 2006, he was awarded the prestigious Movement Disorders Research Award by the American Academy of Neurology which recognises an individual for outstanding work in the field of Parkinson’s disease or other movement disorders for either a single outstanding contribution or for lifetime achievement. The following year he was elected Fellow of the Academy of Medical Sciences and received a NIHR Senior Investigators Award in 2008.

In 2007 he delivered the Gowers Memorial Lecture at the National Hospital and in 2010 he delivered the Melvin Yahr Memorial Lecture at Mount Sinai Hospital New York and the inaugural Lord Brain Memorial Lecture at Barts and the Royal London Hospitals.

Professor Lees is an original member of the Highly Cited Researchers ISI Database. He is Visiting Professor to both the University of Liverpool and the Universidade Federal de Ceara, Fortaleza, Brazil and in 2010 was elected an overseas member of the Academia Nacional de Medicina, Brazil; he is also an elected overseas member of fifteen national neurological societies.

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Number of items: 1534.

2018

Weil, RS; McColgan, P; Schrag, AE; Warren, JD; Crutch, SJ; Lees, AJ; Morris, HR; (2018) Reply: MRI findings of visual system alterations in Parkinson’s disease. Brain (In press).

2017

Athauda, D; Maclagan, K; Skene, SS; Bajwa-Joseph, M; Letchford, D; Chowdhury, K; Hibbert, S; ... Foltynie, T; + view all (2017) Exenatide once weekly versus placebo in Parkinson's disease: a randomised, double-blind, placebo-controlled trial. The Lancet 10.1016/S0140-6736(17)31585-4. (In press).

Boes, CJ; Toodayan, N; Lees, A; (2017) Finding the grave of Sir William Richard Gowers. Practical Neurology , 17 (4) pp. 321-322. 10.1136/practneurol-2017-001648. Green open access
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De Pablo-Fernandez, E; Tur, C; Revesz, T; Lees, AJ; Holton, JL; Warner, TT; (2017) Association of Autonomic Dysfunction With Disease Progression and Survival in Parkinson Disease. JAMA Neurology 10.1001/jamaneurol.2017.1125. (In press).

Geissler, JM; International Parkinson Disease Genomics Consortium members, ; Romanos, M; Gerlach, M; Berg, D; Schulte, C; (2017) No genetic association between attention-deficit/hyperactivity disorder (ADHD) and Parkinson's disease in nine ADHD candidate SNPs. Atten Defic Hyperact Disord , 9 (2) pp. 121-127. 10.1007/s12402-017-0219-8.

Hansson, O; Janelidze, S; Hall, S; Magdalinou, N; Lees, AJ; Andreasson, U; Norgren, N; ... Swedish BioFINDER Study, .; + view all (2017) Blood-based NfL: A biomarker for differential diagnosis of parkinsonian disorder. Neurology , 88 (10) pp. 930-937. 10.1212/WNL.0000000000003680. Green open access
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Jansen, IE; Ye, H; Heetveld, S; Lechler, MC; Michels, H; Seinstra, RI; Lubbe, SJ; ... Heutink, P; + view all (2017) Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing. Genome Biology , 18 , Article 22. 10.1186/s13059-017-1147-9. Green open access
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Kempster, PA; Hurwitz, B; Lees, AJ; (2017) James Parkinson’s chimera: Syndrome or disease? Journal of the Royal College of Physicians of Edinburgh , 47 (2) pp. 190-195. 10.4997/JrCPe.2017.220. Green open access
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Kun-Rodrigues, C; Ross, OA; Orme, T; Shepherd, C; Parkkinen, L; Darwent, L; Hernandez, D; ... Bras, J; + view all (2017) Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies. Neurobiology of Aging , 49 214.e13-214.e15. 10.1016/j.neurobiolaging.2016.08.023. Green open access
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Lees, AJ; (2017) William Burroughs: Sailor of the Soul. Journal of Psychoactive Drugs 10.1080/02791072.2017.1357862. (In press).

Lees, AJ; Ferreira, J; Rascol, O; Poewe, W; Rocha, J-F; McCrory, M; Soares-da-Silva, P; (2017) Opicapone as Adjunct to Levodopa Therapy in Patients With Parkinson Disease and Motor Fluctuations: A Randomized Clinical Trial. JAMA Neurol , 74 (2) pp. 197-206. 10.1001/jamaneurol.2016.4703.

Lees, AJ; Ferreira, J; Rascol, O; Reichmann, H; Stocchi, F; Tolosa, E; Poewe, W; (2017) Opicapone for the management of end-of-dose motor fluctuations in patients with Parkinson's disease treated with L-DOPA. Expert Review of Neurotherapeutics , 17 (7) pp. 649-659. 10.1080/14737175.2017.1336086.

Lees, AJ; Rocha, J-F; Soares-da-Silva, P; (2017) Concerns Regarding Opicapone as Adjunct to Levodopa Therapy-Reply. JAMA Neurol , 74 (7) 873-. 10.1001/jamaneurol.2017.0726.

Ling, H; Morris, HR; Neal, JW; Lees, AJ; Hardy, J; Holton, JL; Revesz, T; (2017) Mixed pathologies including chronic traumatic encephalopathy account for dementia in retired Association football (soccer) players. Presented at: 118th Meeting of the British-Neuropathological-Society, Royal Coll Phys, London, ENGLAND.

Magdalinou, NK; Noyce, AJ; Pinto, R; Lindstrom, E; Holmen-Larsson, J; Holtta, M; Blennow, K; ... Gobom, J; + view all (2017) Identification of candidate cerebrospinal fluid biomarkers in parkinsonism using quantitative proteomics. Parkinsonism & Related Disorders , 37 pp. 65-71. 10.1016/j.parkreldis.2017.01.016.

Massey, LA; Miranda, MA; Al-Helli, O; Parkes, HG; Thornton, JS; So, PW; White, MJ; ... Yousry, TA; + view all (2017) 9.4 T MR microscopy of the substantia nigra with pathological validation in controls and disease. NeuroImage: Clinical , 13 pp. 154-163. 10.1016/j.nicl.2016.11.015. Green open access
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Noyce, AJ; Kia, DA; Hemani, G; Nicolas, A; Price, TR; De Pablo-Fernandez, E; Haycock, PC; ... Wood, NW; + view all (2017) Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study. PLoS Medicine , 14 (6) , Article e1002314. 10.1371/journal.pmed.1002314. Green open access
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Noyce, AJ; R'Bibo, L; Peress, L; Bestwick, JP; Adams-Carr, KL; Mencacci, NE; Hawkes, CH; ... Schrag, A; + view all (2017) PREDICT-PD: An online approach to prospectively identify risk indicators of Parkinson's disease. Movement Disorders , 32 (2) pp. 219-226. 10.1002/mds.26898. Green open access
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Pakpoor, J; Noyce, A; Goldacre, R; Selkihova, M; Mullin, S; Schrag, A; Lees, A; (2017) Viral hepatitis and Parkinson disease A national record-linkage study. Neurology , 88 (17) pp. 1630-1633. 10.1212/WNL.0000000000003848.

Pedroso, JL; Linden, SC; Barsottini, OG; Maranhão, P; Lees, AJ; (2017) The relationship between the First World War and neurology: 100 years of "Shell Shock". Arquivos de Neuro-Psiquiatria , 75 (5) pp. 317-319. 10.1590/0004-282X20170046. Green open access
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Simone, R; Javad, F; Emmett, W; Ehteramyan, M; Zuccotti, P; Modelska, A; Siva, K; ... de Silva, R; + view all (2017) Antisense long non-coding RNA represses MAPT translation through an embedded MIR repeat. Presented at: 118th Meeting of the British-Neuropathological-Society, Royal Coll Phys, London, ENGLAND.

Teive, HA; Barbosa, ER; Lees, AJ; (2017) Wilson's disease: the 60th anniversary of Walshe's article on treatment with penicillamine. Arquivos de Neuro-Psiquiatria , 75 (1) pp. 69-71. 10.1590/0004-282X20160166. Green open access
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Teive, HAG; Lees, AJ; (2017) Georges Simenon, Inspector Maigret and his relevance to the practice of Neurology. Arquivos de Neuro-Psiquiatria , 75 (3) pp. 189-191. 10.1590/0004-282X20170019. Green open access
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Teive, HAG; Munhoz, RP; Lees, AJ; (2017) Parkinson's disease - 200 years: the outstanding contribution of "Old Hubert". Arquivos de Neuro-Psiquiatria , 75 (3) pp. 192-194. 10.1590/0004-282X20170006. Green open access
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Witoelar, A; Jansen, IE; Wang, Y; Desikan, RS; Gibbs, JR; Blauwendraat, C; Thompson, WK; ... International Parkinson’s Disease Genomics Consortium (IPDGC), N, .; + view all (2017) Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases. JAMA Neurology , 74 (7) pp. 780-792. 10.1001/jamaneurol.2017.0469.

2016

Adams-Carr, KL; Bestwick, JP; Shribman, S; Lees, A; Schrag, A; Noyce, AJ; (2016) Constipation preceding Parkinson's disease: a systematic review and meta-analysis. J Neurol Neurosurg Psychiatry , 87 (7) pp. 710-716. 10.1136/jnnp-2015-311680. Green open access
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Bang, J; Lobach, IV; Lang, AE; Grossman, M; Knopman, DS; Miller, BL; Schneider, LS; ... AL-108-231 Investigators, .; + view all (2016) Predicting disease progression in progressive supranuclear palsy in multicenter clinical trials. Parkinsonism Relat Disord , 28 pp. 41-48. 10.1016/j.parkreldis.2016.04.014.

Barbosa, P; Lees, AJ; Magee, C; Djamshidian, A; Warner, TT; (2016) A retrospective evaluation of the frequency of impulsive compulsive behaviours in Parkinson’s disease patients treated with continuous waking day apomorphine pumps. Movement Disorders Clinical Practice 10.1002/mdc3.12416. (In press).

Borgemeester, RW; Lees, AJ; van Laar, T; (2016) Parkinson's disease, visual hallucinations and apomorphine: a review of the available evidence. Parkinsonism & Related Disorders , 27 pp. 35-40. 10.1016/j.parkreldis.2016.04.023. Green open access
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Doherty, KM; De Pablo-Fernandez, E; Houlden, H; Polke, JM; Lees, AJ; Warner, TT; Holton, JL; (2016) MSA-C or SCA 17? A clinicopathological case update. Movement Disorders , 31 (10) pp. 1582-1584. 10.1002/mds.26741.

Ferreira, JJ; Lees, A; Rocha, JF; Poewe, W; Rascol, O; Soares-da-Silva, P; (2016) Opicapone as an adjunct to levodopa in patients with Parkinson's disease and end-of-dose motor fluctuations: a randomised, double-blind, controlled trial. The Lancet Neurology , 15 (2) pp. 154-165. 10.1016/S1474-4422(15)00336-1.

Guerreiro, R; Escott-Price, V; Darwent, L; Parkkinen, L; Ansorge, O; Hernandez, DG; Nalls, MA; ... Bras, J; + view all (2016) Genome-wide analysis of genetic correlation in dementia with Lewy bodies, Parkinson's and Alzheimer's diseases. Neurobiology of Aging , 38 214.e7-214.e10. 10.1016/j.neurobiolaging.2015.10.028. Green open access
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Lamb, R; Darvell, M; Woodside, J; Rohrer, J; Lees, A; Morris, H; (2016) CORTICOBASAL SYNDROME AND CORTICOBASAL DEGENERATION. Presented at: Annual Meeting of the Association-of-British-Neurologists (ABN), Brighton, ENGLAND.

Lamb, R; Rohrer, JD; Lees, AJ; Morris, HR; (2016) Progressive Supranuclear Palsy and Corticobasal Degeneration: Pathophysiology and Treatment Options. Current Treatment Options in Neurology , 18 (9) , Article 42. 10.1007/s11940-016-0422-5. Green open access
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Lincoln, L; Fisher, R; Jackson, MJ; Jenner, P; Neumeyer, J; Sromek, AW; Lees, AJ; (2016) Oral r-(-)-11-o-valeryl-n-n-propylnoraporphine reverses motor deficits in mptp-treated marmosets. Movement Disorders , 31 pp. 1381-1388. 10.1002/mds.26626.

Mok, KY; Sheerin, U; Simón-Sánchez, J; Salaka, A; Chester, L; Escott-Price, V; Mantripragada, K; ... Wood, NW; + view all (2016) Deletions at 22q11.2 in idiopathic Parkinson's disease: a combined analysis of genome-wide association data. Lancet Neurology , 15 (6) pp. 585-596. 10.1016/S1474-4422(16)00071-5. Green open access
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Moriyama, TS; Chagas, MHN; Silveira-Moriyama, L; Tumas, V; Lees, AJ; Crippa, JA; Bressan, RA; (2016) Diagnosing social anxiety in Parkinson’s disease: Characteristics and frequencies according to two diagnostic criteria. Revista de Psiquiatria Clinica , 43 (6) pp. 139-142. 10.1590/0101-60830000000100. Green open access
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Noyce, AJ; Lees, AJ; Schrag, AE; (2016) The prediagnostic phase of Parkinson's disease. Journal of Neurology, Neurosurgery and Psychiatry 10.1136/jnnp-2015-311890. (In press). Green open access
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Noyce, AJ; Schrag, A; Masters, JM; Bestwick, JP; Giovannoni, G; Lees, AJ; (2016) Subtle motor disturbances in PREDICT-PD participants. Journal of Neurology, Neurosurgery and Psychiatry , 88 pp. 212-217. 10.1136/jnnp-2016-314524. Green open access
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Pillas, M; Selai, C; Quinn, NP; Lees, A; Litvan, I; Lang, A; Bower, J; ... Schrag, A; + view all (2016) Development and validation of a carers quality-of-life questionnaire for parkinsonism (PQoL Carers). QUALITY OF LIFE RESEARCH , 25 (1) pp. 81-88. 10.1007/s11136-015-1071-y.

Sailer, A; Scholz, SW; Nalls, MA; Schulte, C; Federoff, M; Price, TR; Lees, A; ... European Multiple System Atrophy Study Group and the UK Multiple, ; + view all (2016) A genome-wide association study in multiple system atrophy. Neurology , 87 (15) pp. 1591-1598. 10.1212/WNL.0000000000003221. Green open access
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Selikhova, M; Tripoliti, E; Fedoryshyn, L; Matvienko, Y; Stanetska, H; Boychuk, M; Komnatska, I; ... Sanotsky, Y; + view all (2016) Analysis of a distinct speech disorder seen in chronic manganese toxicity following Ephedrone abuse. Clinical Neurology and Neurosurgery , 147 pp. 71-77. 10.1016/j.clineuro.2016.05.027.

Stamelou, M; Schöpe, J; Wagenpfeil, S; Del Ser, T; Bang, J; Lobach, IY; Luong, P; ... AL-108-231 Investigators, Tauros Investigators, and MDS-Endorsed, .; + view all (2016) Power calculations and placebo effect for future clinical trials in progressive supranuclear palsy. Movement Disorders , 31 (5) pp. 742-747. 10.1002/mds.26580.

Weil, RS; Schrag, AE; Warren, JD; Crutch, SJ; Lees, AJ; Morris, HR; (2016) Visual dysfunction in Parkinson's disease. Brain 10.1093/brain/aww175. (In press). Green open access
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Yarnall, AJ; Lashley, T; Ling, H; Lees, AJ; Coleman, SY; O'Sullivan, SS; Compta, Y; ... Burn, DJ; + view all (2016) Apomorphine: A potential modifier of amyloid deposition in Parkinson's disease? Movement Disorders , 31 (5) pp. 668-675. 10.1002/mds.26422.

2015

Adams-Carr, K; Schrag, A; Shribman, S; Bestwick, J; Lees, A; Noyce, A; (2015) CONSTIPATION PRECEDING PARKINSON'S DISEASE-META-ANALYSIS. In: (Proceedings) Annual Meeting of the Association-of-British-Neurologists (ABN). BMJ PUBLISHING GROUP

Bertolin, G; Jacoupy, M; Traver, S; Ferrando-Miguel, R; Saint Georges, T; Grenier, K; Ardila-Osorio, H; ... Corti, O; + view all (2015) Parkin maintains mitochondrial levels of the protective Parkinson's disease-related enzyme 17-β hydroxysteroid dehydrogenase type 10. Cell Death Differ , 22 (10) pp. 1563-1576. 10.1038/cdd.2014.224.

Donnabella Bastos, LO; Guerreiro, MM; Lees, AJ; Warner, TT; Silveira-Moriyama, L; (2015) Effects of Age and Cognition on a Cross-Cultural Paediatric Adaptation of the Sniffin' Sticks Identification Test. PLOS ONE , 10 (8) 10.1371/journal.pone.0131641.

Ferrari, R; Ryten, M; Simone, R; Trabzuni, D; Nicolaou, N; Hondhamuni, G; Ramasamy, A; ... de Silva, R; + view all (2015) Corrigendum to "Assessment of common variability and expression quantitative trait loci for genome-wide associations for progressive supranuclear palsy." [Neurobiol. Aging 35 (2014) 1514.e1-1514.e12]. Neurobiol Aging , 36 (11) 3118-. 10.1016/j.neurobiolaging.2015.10.005.

Kiely, AP; Ling, H; Asi, YT; Kara, E; Limousin, P; Lewis, P; Proukakis, C; ... Holton, JL; + view all (2015) Distinct clinical and neuropathological features of G51D SNCA mutation cases compared with SNCA duplication and H50Q mutation. In: (Proceedings) 116th Meeting of the British-Neuropathological-Society. (pp. p. 31). WILEY-BLACKWELL

Kiely, AP; Ling, H; Asi, YT; Kara, E; Proukakis, C; Schapira, AH; Morris, HR; ... Holton, JL; + view all (2015) Distinct clinical and neuropathological features of G51D SNCA mutation cases compared with SNCA duplication and H50Q mutation. In: BIOMED CENTRAL LTD

Kiely, AP; Ling, H; Asi, YT; Kara, E; Proukakis, C; Schapira, AH; Morris, HR; ... Holton, JL; + view all (2015) Distinct clinical and neuropathological features of G51D SNCA mutation cases compared with SNCA duplication and H50Q mutation. Molecular Neurodegeneration , 10 , Article 41. 10.1186/s13024-015-0038-3. Green open access
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Lees, A; Sikk, K; Taba, P; (2015) The Story of "Speed" from "Cloud Nine" to Brain Gain. Int Rev Neurobiol , 120 pp. 1-7. 10.1016/bs.irn.2015.03.001.

Lees, AJ; (2015) The strange case of Dr. William Gowers and Mr. Sherlock Holmes. Brain , 138 (Pt 7) pp. 2103-2108. 10.1093/brain/awv144.

Lees, AJ; Tolosa, E; Olanow, CW; (2015) Four pioneers of L-dopa treatment: Arvid Carlsson, Oleh Hornykiewicz, George Cotzias, and Melvin Yahr. Mov Disord , 30 (1) pp. 19-36. 10.1002/mds.26120.

Ling, H; Asi, YT; Petrovic, IN; Ahmed, Z; Prashanth, LK; Hazrati, LN; Nishizawa, M; ... Holton, JL; + view all (2015) Minimal change multiple system atrophy: An aggressive variant? Movement Disorders , 30 (7) pp. 960-967. 10.1002/mds.26220.

Ling, H; Kearney, S; Yip, HL; Silveira-Moriyama, L; Revesz, T; Holton, JL; Strand, C; ... Lees, AJ; + view all (2015) Parkinson's disease without nigral degeneration: a pathological correlate of scans without evidence of dopaminergic deficit (SWEDD)? J Neurol Neurosurg Psychiatry 10.1136/jnnp-2015-310756. Green open access
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Loane, C; Wu, K; O'Sullivan, SS; Lawrence, AD; Woodhead, Z; Lees, AJ; Piccini, P; (2015) Psychogenic and neural visual-cue response in PD dopamine dysregulation syndrome. PARKINSONISM & RELATED DISORDERS , 21 (11) pp. 1336-1341. 10.1016/j.parkreldis.2015.09.042.

Magdalinou, NK; Paterson, RW; Schott, JM; Fox, NC; Mummery, C; Blennow, K; Bhatia, K; ... Zetterberg, H; + view all (2015) A panel of nine cerebrospinal fluid biomarkers may identify patients with atypical parkinsonian syndromes. J Neurol Neurosurg Psychiatry 10.1136/jnnp-2014-309562.

Miranda, M; Bustamante, ML; Mena, F; Lees, A; (2015) Original footage of the Chilean miners with manganism published in Neurology in 1967. Neurology , 85 (24) pp. 2166-2169. 10.1212/WNL.0000000000002223.

Nagy, A; Noyce, A; Velayos, AB; Lees, AJ; Warner, TT; Ling, H; (2015) Late emergence of parkinsonian phenotype and abnormal dopamine transporter scan in choreoacanthocytosis. Movement Disorders Clinical Practice

Noyce, AJ; Mencacci, NE; Schrag, A; Bestwick, JP; Giovannoni, G; Lees, AJ; Hardy, J; (2015) Web-based assessment of Parkinson's prodromal markers identifies GBA variants. Mov Disord , 30 (7) pp. 1002-1003. 10.1002/mds.26249. Green open access
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Odin, P; Ray Chaudhuri, K; Slevin, JT; Volkmann, J; Dietrichs, E; Martinez-Martin, P; Krauss, JK; ... National Steering Committees, ; + view all (2015) Collective physician perspectives on non-oral medication approaches for the management of clinically relevant unresolved issues in Parkinson's disease: Consensus from an international survey and discussion program. Parkinsonism Relat Disord , 21 (10) pp. 1133-1144. 10.1016/j.parkreldis.2015.07.020.

Pellicano, C; Niccolini, F; Wu, K; O'Sullivan, SS; Lawrence, AD; Lees, AJ; Piccini, P; (2015) Morphometric changes in the reward system of Parkinson's disease patients with impulse control disorders. JOURNAL OF NEUROLOGY , 262 (12) pp. 2653-2661. 10.1007/s00415-015-7892-3.

Schottlaender, LV; Polke, JM; Ling, H; MacDoanld, ND; Tucci, A; Nanji, T; Pittman, A; ... Houlden, H; + view all (2015) The analysis of C9orf72 repeat expansions in a large series of clinically and pathologically diagnosed cases with atypical parkinsonism (vol 36, 1221.e1, 2015). NEUROBIOLOGY OF AGING , 36 (4) p. 1768. 10.1016/j.neurobiolaging.2015.02.027.

Schottlaender, LV; Polke, JM; Ling, H; MacDoanld, ND; Tucci, A; Nanji, T; Pittman, A; ... Houlden, H; + view all (2015) The analysis of C9orf72 repeat expansions in a large series of clinically and pathologically diagnosed cases with atypical parkinsonism. Neurobiol Aging , 36 (2) 1221.e1 - 1221.e6. 10.1016/j.neurobiolaging.2014.08.024. Green open access
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Schottlaender, LV; Polke, JM; Ling, H; MacDoanld, ND; Tucci, A; Nanji, T; Pittman, A; ... Houlden, H; + view all (2015) The analysis of C9orf72 repeat expansions in a large series of clinically and pathologically diagnosed cases with atypical parkinsonism. Neurobiology of Aging , 36 (2) 1221.e1-1221.e6. 10.1016/j.neurobiolaging.2014.08.024.

Silveira-Moriyama, L; Birchall, J; Bain, P; Lees, AJ; Bajaj, NPS; (2015) Hyposmia in SWEDD. MOVEMENT DISORDERS , 30 (10) pp. 1436-1437. 10.1002/mds.26344.

Silveira-Moriyama, L; Lees, AJ; (2015) How reliable are prodromal indicators of Parkinson disease? Nature Reviews Neurology , 11 (1) pp. 5-6. 10.1038/nrneurol.2014.235.

Silveira-Moriyama, L; Lees, AJ; (2015) PARKINSON DISEASE How reliable are prodromal indicators of Parkinson disease? NATURE REVIEWS NEUROLOGY , 11 (1) 5-U6666. 10.1038/nrneurol.2014.235.

Trenkwalder, C; Chaudhuri, KR; Garcia Ruiz, PJ; LeWitt, P; Katzenschlager, R; Sixel-Doering, F; Henriksen, T; ... Wenzel, K; + view all (2015) Expert Consensus Group report on the use of apomorphine in the treatment of Parkinson's disease - Clinical practice recommendations. PARKINSONISM & RELATED DISORDERS , 21 (9) pp. 1023-1030. 10.1016/j.parkreldis.2015.06.012.

Wu, K; Politis, M; O'Sullivan, SS; Lawrence, AD; Warsi, S; Bose, S; Lees, AJ; (2015) Single versus multiple impulse control disorders in Parkinson's disease: an C-11-raclopride positron emission tomography study of reward cue-evoked striatal dopamine release. JOURNAL OF NEUROLOGY , 262 (6) pp. 1504-1514. 10.1007/s00415-015-7722-7.

2014

Antsov, E; Silveira-Moriyama, L; Kilk, S; Kadastik-Eerme, L; Toomsoo, T; Lees, A; Taba, P; (2014) Adapting the Sniffin' Sticks olfactory test to diagnose Parkinson's disease in Estonia. In: (pp. pp. 830-833). ELSEVIER SCI LTD

Antsov, E; Silveira-Moriyama, L; Kilk, S; Kadastik-Eerme, L; Toomsoo, T; Lees, A; Taba, P; (2014) Adapting the Sniffin' Sticks olfactory test to diagnose Parkinson's disease in Estonia. PARKINSONISM & RELATED DISORDERS , 20 (8) pp. 830-833. 10.1016/j.parkreldis.2014.04.012.

Asi, YT; Ling, H; Ahmed, Z; Lees, AJ; Revesz, T; Holton, JL; (2014) Neuropathological Features of Multiple System Atrophy With Cognitive Impairment. MOVEMENT DISORDERS , 29 (7) pp. 884-888. 10.1002/mds.25887.

Asi, YT; Ling, H; Ahmed, Z; Lees, AJ; Revesz, T; Holton, JL; (2014) Neuropathological features of multiple system atrophy with cognitive impairment. Movement Disorders , 29 (7) pp. 884-888. 10.1002/mds.25887.

Asi, YT; Simpson, JE; Heath, PR; Wharton, SB; Lees, AJ; Revesz, T; Houlden, H; (2014) Alpha-synuclein mRNA expression in oligodendrocytes in MSA. Glia , 62 (6) pp. 964-970. 10.1002/glia.22653. Green open access
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Aviles-Olmos, I; Dickson, J; Kefalopoulou, Z; Djamshidian, A; Kahan, J; Ell, P; Whitton, P; ... Foltynie, T; + view all (2014) Motor and cognitive advantages persist 12 months after exenatide exposure in Parkinson's disease. Journal of Parkinson’s Disease , 4 (3) 337 - 344. 10.3233/JPD-140364. Green open access
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Boxer, AL; Lang, AE; Grossman, M; Knopman, DS; Miller, BL; Schneider, LS; Doody, RS; ... Morimoto, BH; + view all (2014) Davunetide in patients with progressive supranuclear palsy: a randomised, double-blind, placebo-controlled phase 2/3 trial. LANCET NEUROLOGY , 13 (7) pp. 676-685. 10.1016/S1474-4422(14)70088-2.

Boxer, AL; Miller, BL; Koestler, M; Lobach, IV; Heuer, HW; Lang, AE; Grossman, M; ... Morimoto, BH; + view all (2014) Davunetide in patients with progressive supranuclear palsy: A randomised, double-blind, placebo-controlled phase 2/3 trial. The Lancet Neurology , 13 (7) pp. 676-685. 10.1016/S1474-4422(14)70088-2.

Bras, J; Guerreiro, R; Darwent, L; Parkkinen, L; Ansorge, O; Escott-Price, V; Hernandez, DG; ... Hardy, J; + view all (2014) Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies. Hum Mol Genet , 23 (23) 6139 - 6146. 10.1093/hmg/ddu334. Green open access
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Compta, Y; Kempster, P; Parkkinen, L; Selikhova, M; Lashley, T; Holton, JL; Lees, AJ; (2014) The significance of α-synuclein, amyloid-β and tau pathologies in parkinson's disease progression and related dementia. Neurodegenerative Diseases , 13 (2-3) 154 - 156. 10.1159/000354670.

Compta, Y; Parkkinen, L; Kempster, P; Selikhova, M; Lashley, T; Holton, JL; Lees, AJ; (2014) The Significance of alpha-Synuclein, Amyloid-beta and Tau Pathologies in Parkinsn's Disease Progression and Related Dementia. Neurodegenerative Diseases , 13 (2-3) 154 - 156. 10.1159/000354670.

De Pablo-Fernandez, E; Doherty, KM; Holton, JL; Revesz, T; Djamshidian, A; Limousin, P; Bhatia, KP; ... Ling, H; + view all (2014) Concomitant fragile X-associated tremor ataxia syndrome and Parkinson's disease: a clinicopathological report of two cases. J Neurol Neurosurg Psychiatry 10.1136/jnnp-2014-309460. (In press). Green open access
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Djamshidian, A; Lees, AJ; (2014) Can stress trigger Parkinson's disease? JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY , 85 (8) 879-+. 10.1136/jnnp-2013-305911.

Djamshidian, A; Lees, AJ; (2014) Can stress trigger Parkinson's disease? Journal of Neurology, Neurosurgery and Psychiatry , 85 (8) pp. 879-882. 10.1136/jnnp-2013-305911.

Djamshidian, A; Lees, AJ; (2014) Can stress trigger Parkinson's disease? Journal of neurology, neurosurgery, and psychiatry , 85 (8) 878 - 881.

Djamshidian, A; O'Sullivan, SS; Lawrence, AD; Foltynie, T; Aviles-Olmos, I; Magdalinou, N; Tomassini, A; ... Averbeck, BB; + view all (2014) Perceptual decision-making in patients with Parkinson's disease. JOURNAL OF PSYCHOPHARMACOLOGY , 28 (12) pp. 1149-1154. 10.1177/0269881114548437.

Djamshidian, A; O'Sullivan, SS; Tomassini, A; Foltynie, T; Limousin, P; Aviles-Olmos, I; Warner, TT; ... Averbeck, BB; + view all (2014) In a Rush to Decide: Deep Brain Stimulation and Dopamine Agonist Therapy in Parkinson's Disease. JOURNAL OF PARKINSONS DISEASE , 4 (4) pp. 579-583. 10.3233/JPD-140388.

Doherty, KM; Warner, TT; Lees, AJ; (2014) Late Onset Ataxia: MSA-C or SCA 17? A Gene Penetrance Dilemma. MOVEMENT DISORDERS , 29 (1) pp. 36-38. 10.1002/mds.25770.

Doherty, KM; Warner, TT; Lees, AJ; (2014) Late onset ataxia: MSA-C or SCA 17? A gene penetrance dilemma. Movement Disorders , 29 (1) pp. 36-38. 10.1002/mds.25770.

Dunn, L; Allen, G; Ling, H; Li, A; Duberly, K; Hargreaves, I; Lees, A; ... Bandopadhyay, R; + view all (2014) Perturbed glucose metabolism in Parkinson's disease. In: (Proceedings) 115th Meeting of the British-Neuropathological-Society, Institute-of-Child-Health. (pp. pp. 13-14). WILEY-BLACKWELL

Dunn, L; Allen, GF; Mamais, A; Ling, H; Li, A; Duberley, KE; Hargreaves, IP; ... Bandopadhyay, R; + view all (2014) Dysregulation of glucose metabolism is an early event in sporadic Parkinson's disease. Neurobiol Aging , 35 (5) pp. 1111-1115. 10.1016/j.neurobiolaging.2013.11.001. Green open access
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Dunn, L; Allen, GFG; Mamais, A; Ling, H; Li, A; Duberley, KE; Hargreaves, IP; ... Bandopadhyay, R; + view all (2014) Dysregulation of glucose metabolism is an early event in sporadic Parkinson's disease. Neurobiology of Aging , 35 (5) pp. 1111-1115. 10.1016/j.neurobiolaging.2013.11.001.

Eggert, K; Oertel, WH; Lees, AJ; German Competence Network on Parkinson’s disease, ; (2014) Safety and efficacy of tolcapone in the long-term use in Parkinson disease: an observational study. Clin Neuropharmacol , 37 (1) pp. 1-5. 10.1097/WNF.0000000000000008.

Erro, R; Lees, AJ; Moccia, M; Picillo, M; Penco, S; Mosca, L; Vitale, C; (2014) Progressive parkinsonism, balance difficulties, and supranuclear gaze palsy. JAMA Neurol , 71 (1) pp. 104-107. 10.1001/jamaneurol.2013.5149.

Ferrari, R; Ryten, M; Simone, R; Trabzuni, D; Nicolaou, N; Hondhamuni, G; Ramasamy, A; ... de Silva, R; + view all (2014) Assessment of common variability and expression quantitative trait loci for genome-wide associations for progressive supranuclear palsy. NEUROBIOLOGY OF AGING , 35 (6) 10.1016/j.neurobiolaging.2014.01.010.

Kiely, AP; Asi, YT; Kara, E; Limousin, P; Ling, H; Lewis, P; Proukakis, C; ... Holton, JL; + view all (2014) How do G51D SNCA mutation cases compare clinically and neuropathologically to SNCA duplication and H50Q SNCA mutation? In: (Proceedings) 115th Meeting of the British-Neuropathological-Society, Institute-of-Child-Health. (pp. pp. 11-12). WILEY-BLACKWELL

Lees, A; Chaudhuri, KR; Isaacson, SH; (2014) Twenty years of apomorphine therapy – how does it compare with Levodopa?: Highlights of a satellite symposium held at the 18th international congress of parkinson’s disease and movement disorders, Stockholm, 8–12 june 2014. European Neurological Review , 9 (2) pp. 113-119. 10.17925/ENR.2014.09.02.113.

Ling, H; Holton, JL; Lees, AJ; Revesz, T; (2014) TDP-43 pathology is present in most post-encephalitic parkinsonism brains. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY , 40 (5) pp. 654-657. 10.1111/nan.12067.

Ling, H; Kara, E; Revesz, T; Lees, AJ; Plant, GT; Martino, D; Houlden, H; ... Holton, JL; + view all (2014) Concomitant progressive supranuclear palsy and chronic traumatic encephalopathy in a boxer. In: (Proceedings) 115th Meeting of the British-Neuropathological-Society, Institute-of-Child-Health. (pp. pp. 40-41). WILEY-BLACKWELL

Ling, H; Kara, E; Revesz, T; Lees, AJ; Plant, GT; Martino, D; Houlden, H; ... Holton, JL; + view all (2014) Concomitant progressive supranuclear palsy and chronic traumatic encephalopathy in a boxer. Acta Neuropathol Commun , 2 (1) , Article 24. 10.1186/2051-5960-2-24. Green open access
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Ling, H; Lees, A; Kara, E; de Silva, R; Li, A; Kiely, A; Courtney, R; ... Revesz, T; + view all (2014) Slowly progressive L-dopa responsive parkinsonism with neurofibrillary tangle pathology: A new clinicopathological entity? In: (Proceedings) 115th Meeting of the British-Neuropathological-Society, Institute-of-Child-Health. (pp. p. 13). WILEY-BLACKWELL

Ling, H; de Silva, R; Massey, LA; Courtney, R; Hondhamuni, G; Bajaj, N; Lowe, J; ... Revesz, T; + view all (2014) Characteristics of progressive supranuclear palsy presenting with corticobasal syndrome: a cortical variant. Neuropathol Appl Neurobiol , 40 (2) 149 - 163. 10.1111/nan.12037. Green open access
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Magdalinou, N; Lees, AJ; Zetterberg, H; (2014) Cerebrospinal fluid biomarkers in parkinsonian conditions: an update and future directions. Journal of Neurology, Neurosurgery & Psychiatry , 85 (10) pp. 1065-1075. 10.1136/jnnp-2013-307539. Green open access
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Massey, LA; (2014) Clinical and radiological studies in PSP and related conditions. Doctoral thesis, UCL (University College London). Green open access
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Mencacci, NE; Isaias, IU; Reich, MM; Ganos, C; Plagnol, V; Polke, JM; Bras, J; ... Consortium, U-E; + view all (2014) Parkinson's disease in GTP cyclohydrolase 1 mutation carriers. BRAIN , 137 pp. 2480-2492. 10.1093/brain/awu179.

Mencacci, NE; Isaias, IU; Reich, MM; Ganos, C; Plagnol, V; Polke, JM; Bras, J; ... on behalf of the International Parkinson’s Disease Genomics Cons, ; + view all (2014) Parkinson's disease in GTP cyclohydrolase 1 mutation carriers. Brain , 137 (9) pp. 2480-2492. 10.1093/brain/awu179. Green open access
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Noyce, AJ; Bestwick, JP; Silveira-Moriyama, L; Hawkes, CH; Knowles, CH; Hardy, J; Giovannoni, G; ... Schrag, A; + view all (2014) PREDICT-PD: Identifying risk of Parkinson's disease in the community: Methods and baseline results. Journal of Neurology, Neurosurgery and Psychiatry , 85 (1) pp. 31-37. 10.1136/jnnp-2013-305420.

Noyce, AJ; Nagy, A; Acharya, S; Hadavi, S; Bestwick, JP; Fearnley, J; Lees, AJ; (2014) Bradykinesia-Akinesia Incoordination Test: Validating an Online Keyboard Test of Upper Limb Function. PLOS ONE , 9 (4) 10.1371/journal.pone.0096260.

Noyce, AJ; Nagy, A; Acharya, S; Hadavi, S; Bestwick, JP; Fearnley, J; Lees, AJ; (2014) Bradykinesia-Akinesia Incoordination Test: Validating an Online Keyboard Test of Upper Limb Function. PLOS ONE , 9 (4) , Article ARTN e96260. 10.1371/journal.pone.0096260. Green open access
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Parkkinen, L; Lees, AJ; (2014) Is levodopa toxic?: Insights from pathological studies. Focus on Parkinson's Disease , 24 (1) pp. 16-20.

Poewe, W; Lees, A; Chaudhuri, KR; Isaacson, S; (2014) New perspectives in non-oral drug delivery in Parkinson's disease highlights of a satellite symposium held at the XX world congress on Parkinson's disease and related disorders, Geneva, Switzerland, 8-11 December 2013. European Neurological Review , 9 (1)

Silveira-Moriyama, L; Barbosa, ER; Caramelli, P; Zijlmans, J; Lees, AJ; (2014) Vascular dementia and parkinsonism. pp. 199-211. 10.1007/978-1-4471-6365-7_12.

Silveira-Moriyama, L; Ryten, M; Forabosco, P; Lees, A; Houlden, H; Hardy, J; Warner, T; (2014) White matter involvement may explain phenotypic pleiotropy amongst genes involved in episodic movement disorders. In: (Proceedings) 28th Annual Meeting of the Blue-Ribbon-Section of the Movement-Disorders-Society. (pp. pp. 1847-1848). WILEY-BLACKWELL

Tolosa, E; Litvan, I; Höglinger, GU; Burn, D; Lees, A; Andrés, MV; Gómez-Carrillo, B; ... TAUROS Investigators, ; + view all (2014) A phase 2 trial of the GSK-3 inhibitor tideglusib in progressive supranuclear palsy. Mov Disord , 29 (4) pp. 470-478. 10.1002/mds.25824.

Torkamani, M; McDonald, L; Aguayo, IS; Kanios, C; Katsanou, MN; Madeley, L; Limousin, PD; ... Jahanshahi, M; + view all (2014) A Randomized Controlled Pilot Study to Evaluate a Technology Platform for the Assisted Living of People with Dementia and their Carers. J Alzheimers Dis , 41 (2) pp. 515-523. 10.3233/JAD-132156. Green open access
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Torsney, KM; Noyce, AJ; Doherty, KM; Lees, AJ; Bestwick, JP; Dobson, R; (2014) Bone health in Parkinson's disease: A systematic review and meta-analysis. Journal of Neurology, Neurosurgery and Psychiatry , 85 (10) pp. 1159-1166. 10.1136/jnnp-2013-307307. Green open access
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Tsika, E; Glauser, L; Moser, R; Fiser, A; Daniel, G; Sheerin, UM; Lees, A; ... Moore, DJ; + view all (2014) Parkinson's Disease-Linked Mutations in VPS35 Induce Dopaminergic Neurodegeneration. Hum Mol Genet , 23 (17) pp. 4621-4638. 10.1093/hmg/ddu178. Green open access
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Wu, K; Politis, M; O'Sullivan, SS; Lawrence, AD; Warsi, S; Lees, A; Piccini, P; (2014) Problematic Internet use in Parkinson's disease. PARKINSONISM & RELATED DISORDERS , 20 (5) pp. 482-487. 10.1016/j.parkreldis.2014.01.019.

Wu, K; Politis, M; O'Sullivan, SS; Lawrence, AD; Warsi, S; Lees, A; Piccini, P; (2014) Problematic Internet use in Parkinson's disease. Parkinsonism and Related Disorders , 20 (5) pp. 482-487. 10.1016/j.parkreldis.2014.01.019.

2013

Ahmed, Z; Asi, YT; Lees, AJ; Revesz, T; Holton, JL; (2013) Identification and Quantification of Oligodendrocyte Precursor Cells in Multiple System Atrophy, Progressive Supranuclear Palsy and Parkinson's Disease. BRAIN PATHOLOGY , 23 (3) pp. 263-273. 10.1111/j.1750-3639.2012.00637.x.

Ahmed, Z; Asi, YT; Lees, AJ; Revesz, T; Holton, JL; (2013) Identification and quantification of oligodendrocyte precursor cells in multiple system atrophy, progressive supranuclear palsy and parkinson's disease. Brain Pathology , 23 (3) pp. 263-273. 10.1111/j.1750-3639.2012.00637.x.

Asi, YT; Houlden, H; Lees, AJ; Revesz, T; Holton, JL; (2013) Regional expression of alpha-synuclein in multiple system atrophy. MOVEMENT DISORDERS , 28 S277-S277.

Asi, YT; Ling, H; Ahmed, Z; Lees, AJ; Revesz, T; Holton, JL; (2013) Cognitive impairment in multiple system atrophy: a clinico-pathological study. In: (Proceedings) 114th Meeting of the British-Neuropathological-Society / Symposium on Advances in Motor Neuron Diseases. (pp. p. 36). WILEY-BLACKWELL

Averbeck, BB; Djamshidian, A; O'Sullivan, SS; Housden, CR; Roiser, JP; (2013) Uncertainty About Mapping Future Actions Into Rewards May Underlie Performance on Multiple Measures of Impulsivity in Behavioral Addiction: Evidence From Parkinson's Disease. BEHAVIORAL NEUROSCIENCE , 127 (2) pp. 245-255. 10.1037/a0032079.

Aviles-Olmos, I; Dickson, J; Kefalopoulou, Z; Djamshidian, A; Ell, P; Soderlund, T; Whitton, P; ... Foltynie, T; + view all (2013) Exenatide and the treatment of patients with Parkinson's disease. JOURNAL OF CLINICAL INVESTIGATION , 123 (6) pp. 2730-2736. 10.1172/JCI68295.

Aviles-Olmos, I; Limousin, P; Lees, A; Foltynie, T; (2013) Parkinson's disease, insulin resistance and novel agents of neuroprotection. BRAIN , 136 pp. 374-384. 10.1093/brain/aws009.

Boxer, A; Lang, A; Grossman, M; Knopman, D; Miller, B; Schneider, L; Doody, R; ... Gold, M; + view all (2013) Davunetide for progressive supranuclear palsy: Results of the AL-108-231, phase 2/3, 52 week, multi-center, randomized, double-blind, placebo-controlled clinical trial. In: (pp. E202-E202).

Brundin, P; Barker, RA; Conn, PJ; Dawson, TM; Kieburtz, K; Lees, AJ; Schwarzschild, MA; ... Wyse, RKH; + view all (2013) Linked Clinical Trials - The Development of New Clinical Learning Studies in Parkinson's Disease Using Screening of Multiple Prospective New Treatments. JOURNAL OF PARKINSONS DISEASE , 3 (3) pp. 231-239. 10.3233/JPD-139000.

Compta, Y; Revesz, T; Lees, AJ; (2013) The more cortical amyloid-, the more postural instability in parkinson's disease: More grist to the mill for a link between walking, falling, and remembering? MOVEMENT DISORDERS , 28 (3) pp. 263-264. 10.1002/mds.25283.

Djamshidian, A; O'Sullivan, SS; Foltynie, T; Aviles-Olmos, I; Limousin, P; Noyce, A; Zrinzo, L; ... Averbeck, BB; + view all (2013) Dopamine agonists rather than deep brain stimulation cause reflection impulsivity in Parkinson's disease. MOVEMENT DISORDERS , 28 S130-S130.

Djamshidian, A; O'Sullivan, SS; Foltynie, T; Aviles-Olmos, I; Limousin, P; Noyce, A; Zrinzo, L; ... Averbeck, BB; + view all (2013) Dopamine Agonists Rather than Deep Brain Stimulation Cause Reflection Impulsivity in Parkinson's Disease. JOURNAL OF PARKINSONS DISEASE , 3 (2) pp. 139-144. 10.3233/JPD-130178.

Djamshidian, A; Sanotsky, Y; Matviyenko, Y; O'Sullivan, SS; Sharman, S; Selikhova, M; Fedoryshyn, L; ... Averbeck, BB; + view all (2013) Increased reflection impulsivity in patients with ephedrone-induced Parkinsonism. ADDICTION , 108 (4) pp. 771-779. 10.1111/add.12080.

Djamshidian, A; Sanotsky, Y; Matviyenko, Y; O'Sullivan, SS; Sharman, S; Selikhova, M; Fedoryshyn, L; ... Averbeck, BB; + view all (2013) Increased reflection impulsivity in patients with ephedrone-induced Parkinsonism. Addiction , 108 (4) pp. 771-779. 10.1111/add.12080.

Doherty, K; Davagnanam, I; Molloy, S; Silveira-Moriyama, L; Lees, A; (2013) PISA SYNDROME IN PARKINSON'S DISEASE-A MOBILE OR FIXED DEFORMITY? JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY , 84 (11) 10.1136/jnnp-2013-306573.152.

Doherty, KM; Davagnanam, I; Molloy, S; Silveira-Moriyama, L; Lees, AJ; (2013) Pisa syndrome in Parkinson's disease: a mobile or fixed deformity? Journal of Neurology, Neurosurgery & Psychiatry , 84 (12) 1400 -1403. 10.1136/jnnp-2012-304700. Green open access
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Doherty, KM; Davagnanam, I; Molloy, S; Silveira-Moriyama, L; Lees, AJ; (2013) Pisa syndrome in Parkinson's disease - A fixed deformity? MOVEMENT DISORDERS , 28 S306-S306.

Doherty, KM; Davagnanam, I; Molloy, S; Silveira-Moriyama, L; Lees, AJ; (2013) Pisa syndrome in Parkinson's disease: A mobile or fixed deformity? Journal of Neurology, Neurosurgery and Psychiatry , 84 (12) pp. 1400-1403. 10.1136/jnnp-2012-304700.

Doherty, KM; Rohrer, JD; Lees, AJ; Holton, JL; Warren, J; (2013) Primary progressive aphasia with parkinsonism. MOVEMENT DISORDERS , 28 (6) pp. 741-746. 10.1002/mds.25341.

Doherty, KM; Silveira-Moriyama, L; Parkkinen, L; Healy, DG; Farrell, M; Mencacci, NE; Ahmed, Z; ... Holton, JL; + view all (2013) PARKIN DISEASE-A CLINICOPATHOLOGICAL ENTITY? JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY , 84 (11) 10.1136/jnnp-2013-306573.13.

Doherty, KM; Silveira-Moriyama, L; Parkkinen, L; Healy, DG; Farrell, M; Mencacci, NE; Ahmed, Z; ... Holton, JL; + view all (2013) Parkin Disease A Clinicopathologic Entity? JAMA NEUROLOGY , 70 (5) pp. 571-579. 10.1001/jamaneurol.2013.172.

Doherty, KM; Silveira-Moriyama, L; Parkkinen, L; Healy, DG; Farrell, M; Mencacci, NE; Ahmed, Z; ... Holton, JL; + view all (2013) Parkin disease - a clinicopathological entity? In: (Proceedings) 114th Meeting of the British-Neuropathological-Society / Symposium on Advances in Motor Neuron Diseases. (pp. pp. 11-12). WILEY-BLACKWELL

Doherty, KM; Silveira-Moriyama, L; Parkkinen, L; Healy, DG; Farrell, M; Mencacci, NE; Ahmed, Z; ... Holton, JL; + view all (2013) Parkin disease: A clinicopathologic entity? JAMA Neurology , 70 (5) pp. 571-579. 10.1001/jamaneurol.2013.172.

Duran, R; Mencacci, NE; Angeli, AV; Shoai, M; Deas, E; Houlden, H; Mehta, A; ... Foltynie, T; + view all (2013) The glucocerobrosidase E326K variant predisposes to Parkinson's disease, but does not cause Gaucher's disease. Movement Disorders , 28 (2) 232 - 236. 10.1002/mds.25248. Green open access
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Foltynie, T; Magee, C; James, C; Webster, GJM; Lees, AJ; Limousin, P; (2013) Impact of Duodopa on Quality of Life in Advanced Parkinson's Disease: A UK Case Series. PARKINSONS DISEASE (UNSP 362) 10.1155/2013/362908.

Hadavi, S; Shribman, S; Nagy, A; Acharya, S; Fearnley, J; Dobson, R; Lees, A; ... Noyce, A; + view all (2013) THE BRADYKINESIA-AKINESIA INCOORDINATION TEST: A SIMPLE OBJECTIVE TEST IN MULTIPLE SCLEROSIS. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY , 84 (11) 10.1136/jnnp-2013-306573.184.

Hardy, J; (2013) Reply to Letter: Identical twins with leucine rich repeat kinase type 2 mutations discordant for Parkinson's disease. MOVEMENT DISORDERS , 28 (4) pp. 561-562. 10.1002/mds.25415.

Holmans, P; Moskvina, V; Jones, L; Sharma, M; Vedernikov, A; Buchel, F; Sadd, M; ... Williams, NM; + view all (2013) A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinsons disease. HUMAN MOLECULAR GENETICS , 22 (5) pp. 1039-1049. 10.1093/hmg/dds492.

Kempster, PA; Lees, AJ; (2013) Neurology and detective writing. Pract Neurol , 13 (6) pp. 372-376. 10.1136/practneurol-2013-000597.

Kiely, AP; Asi, YT; Kara, E; Limousin, P; Ling, H; Lewis, P; Proukakis, C; ... Holton, JL; + view all (2013) Clinical and neuropathological features of synucleinopathy associated with G51D SNCA mutation. MOVEMENT DISORDERS , 28 S277-S277.

Kiely, AP; Asi, YT; Kara, E; Limousin, P; Ling, H; Lewis, P; Proukakis, C; ... Holton, JL; + view all (2013) α-Synucleinopathy associated with G51D SNCA mutation: a link between Parkinson's disease and multiple system atrophy? Acta Neuropathologica , 125 (5) 753 - 769. 10.1007/s00401-013-1096-7. Green open access
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Kiely, AP; Asi, YT; Kara, E; Limousin, P; Ling, H; Lewis, P; Proukakis, C; ... Holton, JL; + view all (2013) Synucleinopathy with a G51D a-synuclein mutation: a neuropathological and genetic study. In: (Proceedings) 114th Meeting of the British-Neuropathological-Society / Symposium on Advances in Motor Neuron Diseases. (pp. pp. 39-40). WILEY-BLACKWELL

Kiely, AP; Asi, YT; Ling, H; Lees, AJ; Hardy, J; Revesz, T; Holton, JL; ... Quinn, N; + view all (2013) A-synucleinopathy associated with G51D SNCA mutation: A link between Parkinson's disease and multiple system atrophy? Acta Neuropathologica , 125 (5) 753 - 769. 10.1007/s00401-013-1096-7. Green open access
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Klebe, S; Golmard, JL; Nalls, MA; Saad, M; Singleton, AB; Bras, JM; Hardy, J; ... Wood, NW; + view all (2013) The Val158Met COMT polymorphism is a modifier of the age at onset in Parkinson's disease with a sexual dimorphism. Journal of Neurology, Neurosurgery and Psychiatry , 84 (6) 666 - 673. 10.1136/jnnp-2012-304475. Green open access
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Lees, AC; Newton, I; Balmford, A; (2013) Pheasants, buzzards, and trophic cascades. CONSERVATION LETTERS , 6 (2) pp. 141-144. 10.1111/j.1755-263X.2012.00301.x.

Li, A; Paudel, R; Johnson, R; Courtney, R; Lees, AJ; Holton, JL; Hardy, J; ... Houlden, H; + view all (2013) Pantothenate kinase-associated neurodegeneration is not a synucleinopathy. Neuropathology and Applied Neurobiology , 39 (2) pp. 121-131. 10.1111/j.1365-2990.2012.01269.x. Green open access
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Linden, SC; Jones, E; Lees, AJ; (2013) Shell shock at Queen Square: Lewis Yealland 100 years on. Brain , 136 (Pt 6) pp. 1976-1988. 10.1093/brain/aws331.

Ling, H; Kara, E; Bandopadhyay, R; Hardy, J; Holton, J; Xiromerisiou, G; Lees, A; ... Revesz, T; + view all (2013) TDP-43 pathology in a patient carrying G2019S LRRK2mutation and a novel p.Q124E MAPT. Neurobiology of Aging , 34 (12) 10.1016/j.neurobiolaging.2013.04.011.

Ling, H; Kara, E; Bandopadhyay, R; Hardy, J; Holton, J; Xiromerisiou, G; Lees, A; ... Revesz, T; + view all (2013) TDP-43 pathology in a patient carrying G2019S LRRK2 mutation and a novel p.Q124E MAPT. Neurobiol Aging , 34 (12) 2889.e5 - 2889.e9. 10.1016/j.neurobiolaging.2013.04.011. Green open access
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Ling, H; Lees, AJ; Bajaj, N; (2013) Reduced striatal [(123)I]FP-CIT SPECT in acquired hepatocerebral degeneration. MOVEMENT DISORDERS , 28 S294-S294.

Ling, H; Petrovic, IN; Lang, AE; Lees, AJ; (2013) Reply to letter: Multiple system atrophy-parkinsonism with slow progression and prolonged survival: a diagnostic catch. Mov Disord , 28 (3) 408-. 10.1002/mds.25288.

Magdalinou, NK; Ling, H; Smith, JDS; Schott, JM; Watkins, LD; Lees, AJ; (2013) Normal pressure hydrocephalus or progressive supranuclear palsy? A clinicopathological case series. In: (pp. pp. 1009-1013). SPRINGER HEIDELBERG

Magdalinou, NK; Ling, H; Smith, JDS; Schott, JM; Watkins, LD; Lees, AJ; (2013) Normal pressure hydrocephalus or progressive supranuclear palsy? A clinicopathological case series. JOURNAL OF NEUROLOGY , 260 (4) pp. 1009-1013. 10.1007/s00415-012-6745-6.

Mamais, A; Raja, M; Manzoni, C; Dihanich, S; Lees, A; Moore, D; Lewis, PA; (2013) Divergent α-synuclein solubility and aggregation properties in G2019S LRRK2 Parkinson's disease brains with Lewy Body pathology compared to idiopathic cases. Neurobiol Dis , 58 pp. 183-190. 10.1016/j.nbd.2013.05.017. Green open access
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Massey, LA; Jäger, HR; Paviour, DC; O'Sullivan, SS; Ling, H; Williams, DR; Kallis, C; ... Micallef, C; + view all (2013) The midbrain to pons ratio: a simple and specific MRI sign of progressive supranuclear palsy. Neurology , 80 (20) 1856 - 1861. 10.1212/WNL.0b013e318292a2d2. Green open access
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McNeill, A; Wu, RM; Tzen, KY; Aguiar, PC; Arbelo, JM; Barone, P; Bhatia, K; ... Schapira, AH; + view all (2013) Dopaminergic neuronal imaging in genetic Parkinson's disease: insights into pathogenesis. PLOS ONE , 8 (7) , Article e69190. 10.1371/journal.pone.0069190. Green open access
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Mencacci, N; Pittman, A; Sheerin, U; Charlesworth, G; Hughes, D; Sweeney, M; Wood, N; ... Hardy, J; + view all (2013) A comprehensive diagnostic test for familial and early onset Parkinson's disease based on next-generation sequencing. MOVEMENT DISORDERS , 28 S408-S408.

Munhoz, RP; Teive, HA; Eleftherohorinou, H; Coin, LJ; Lees, AJ; Silveira-Moriyama, L; (2013) Demographic and motor features associated with the occurrence of neuropsychiatric and sleep complications of Parkinson's disease. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY , 84 (8) pp. 883-887. 10.1136/jnnp-2012-304440.

Munhoz, RP; Teive, HA; Eleftherohorinou, H; Coin, LJ; Lees, AJ; Silveira-Moriyama, L; (2013) Demographic and motor features associated with the occurrence of neuropsychiatric and sleep complications of Parkinson's disease. Journal of Neurology, Neurosurgery and Psychiatry , 84 (8) pp. 883-887. 10.1136/jnnp-2012-304440.

Noyce, AJ; Bestwick, JP; Silveira-Moriyama, L; Hawkes, CH; Knowles, C; Hardy, J; Giovannoni, G; ... Schrag, A; + view all (2013) PREDICT-PD study: Online screening algorithm identifying Parkinson's disease risk. MOVEMENT DISORDERS , 28 S389-S389.

Noyce, AJ; Bestwick, JP; Silveira-Moriyama, L; Hawkes, CH; Knowles, CH; Hardy, J; Giovannoni, G; ... Schrag, A; + view all (2013) PREDICT-PD: Identifying risk of Parkinson's disease in the community: methods and baseline results. Journal of Neurology, Neurosurgery and Psychiatry , 85 (1) pp. 31-37. 10.1136/jnnp-2013-305420. Green open access
filefile

O'Sullivan, SS; Wu, K; Politis, M; Lawrence, AD; Evans, AH; Bose, SK; Djamshidian, A; ... Piccini, P; + view all (2013) Cue-induced striatal dopamine release in Parkinson's disease-associated impulsive-compulsive behaviours (vol 134, pg 969, 2011). BRAIN , 136 p. 985. 10.1093/brain/awr163.

Pearce, JMS; Lees, AJ; (2013) Yorkshire's influence on the foundation of British Neurology. Journal of Neurology, Neurosurgery and Psychiatry , 84 (1) pp. 6-9. 10.1136/jnnp-2012-303248.

Pearce, JMS; Lees, AJ; (2013) Yorkshire's influence on the foundation of British Neurology. J Neurol Neurosurg Psychiatry , 84 (1) pp. 6-9. 10.1136/jnnp-2012-303248.

Petrovic, IN; Martin-Bastida, A; Massey, L; Ling, H; O'Sullivan, SS; Williams, DR; Holton, JL; ... Silveira-Moriyama, L; + view all (2013) MM2 subtype of sporadic Creutzfeldt-Jakob disease may underlie the clinical presentation of progressive supranuclear palsy. JOURNAL OF NEUROLOGY , 260 (4) pp. 1031-1036. 10.1007/s00415-012-6752-7.

Petrovic, IN; Martin-Bastida, A; Massey, L; Ling, H; O'Sullivan, SS; Williams, DR; Holton, JL; ... Silveira-Moriyama, L; + view all (2013) MM2 subtype of sporadic Creutzfeldt-Jakob disease may underlie the clinical presentation of progressive supranuclear palsy. Journal of Neurology , 260 (4) pp. 1031-1036. 10.1007/s00415-012-6752-7.

Politis, M; Loane, C; Wu, K; O'Sullivan, SS; Woodhead, Z; Kiferle, L; Lawrence, AD; ... Piccini, P; + view all (2013) Neural response to visual sexual cues in dopamine treatment-linked hypersexuality in Parkinson's disease. BRAIN , 136 pp. 400-411. 10.1093/brain/aws326.

Politis, M; Loane, C; Wu, K; O'Sullivan, SS; Woodhead, Z; Kiferle, L; Lawrence, AD; ... Piccini, P; + view all (2013) Neural response to visual sexual cues in dopamine treatment-linked hypersexuality in Parkinson's disease. Brain , 136 (2) pp. 400-411. 10.1093/brain/aws326.

Rajan, S; Bandopadhyay, R; Kingsbury, A; Ayling, H; Sterlacci, W; Poewe, W; Maier, H; ... Silveira-Moriyama, L; + view all (2013) Using the anterior olfactory nucleus to study lewy pathology in olfactory structures. MOVEMENT DISORDERS , 28 S374-S374.

Rajan, S; Bandopadhyay, R; Kingsbury, A; Ayling, H; Sterlacci, W; Poewe, W; Maier, H; ... Silveira-Moriyama, L; + view all (2013) Using the anterior olfactory nucleus to study Lewy pathology in olfactory structures. In: (Proceedings) 114th Meeting of the British-Neuropathological-Society / Symposium on Advances in Motor Neuron Diseases. (pp. pp. 49-50). WILEY-BLACKWELL

Rajan, S; Parsons, L; Lees, AJ; Silveira-Moriyama, L; (2013) Availability of olfactory bulb: Experience from a british Brain Bank. Arquivos de Neuro-Psiquiatria , 71 (2) pp. 110-112. 10.1590/S0004-282X2013005000005. Gold open access

Rajan, S; Parsons, L; Lees, AJ; Silveira-Moriyama, L; (2013) Availability of olfactory bulb: experience from a British Brain Bank. ARQUIVOS DE NEURO-PSIQUIATRIA , 71 (2) pp. 110-112.

Selikhova, M; Kempster, PA; Revesz, T; Holton, JL; Lees, AJ; (2013) Neuropathological findings in benign tremulous Parkinsonism. MOVEMENT DISORDERS , 28 (2) pp. 145-152. 10.1002/mds.25220.

Selikhova, M; Kempster, PA; Revesz, T; Holton, JL; Lees, AJ; (2013) Neuropathological findings in benign tremulous Parkinsonism. Movement Disorders , 28 (2) pp. 145-152. 10.1002/mds.25220.

Silveira-Moriyama, L; Gardiner, A; Meyer, E; King, MD; Smith, M; Rakshi, K; Parker, A; ... Kurian, MA; + view all (2013) PRRT2 related paroxysmal kinesigenic dyskinesia (PKD). MOVEMENT DISORDERS , 28 S331-S331.

Silveira-Moriyama, L; Gardiner, AR; Meyer, E; King, MD; Smith, M; Rakshi, K; Parker, A; ... Kurian, MA; + view all (2013) Clinical features of childhood-onset paroxysmal kinesigenic dyskinesia with PRRT2 gene mutations. DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY , 55 (4) pp. 327-334. 10.1111/dmcn.12056.

Silveira-Moriyama, L; Gardiner, AR; Meyer, E; King, MD; Smith, M; Rakshi, K; Parker, A; ... Kurian, MA; + view all (2013) Clinical features of childhood-onset paroxysmal kinesigenic dyskinesia with PRRT2 gene mutations. Developmental Medicine and Child Neurology , 55 (4) pp. 327-334. 10.1111/dmcn.12056.

Taba, P; Lees, A; Stern, G; (2013) Erich Harnack (1852-1915) and a short history of apomorphine. Eur Neurol , 69 (6) pp. 321-324. 10.1159/000346762.

Vale, TC; Glass, PG; Lees, A; Cardoso, F; (2013) Gowers' Queen Square case notes on chorea: a 21st century re-appraisal. Eur Neurol , 69 (1) pp. 48-52. 10.1159/000343628.

Vale, TC; Lees, A; Cardoso, F; (2013) A biosketch of William Richard Gowers with a new review of his inpatient case history notes. Arq Neuropsiquiatr , 71 (6) pp. 411-413. 10.1590/0004-282X20130049. Gold open access

2012

Acharya, S; Nagy, A; Budu, C; Treacy, C; Fearnley, J; Lees, AJ; Giovannoni, G; (2012) The new bradykinesia akinesia incoordination (BRAIN) test: People with Parkinson's disease versus healthy controls. In: (pp. S102-S102).

Ahmed, Z; Asi, YT; Sailer, A; Lees, AJ; Houlden, H; Revesz, T; Holton, JL; (2012) The neuropathology, pathophysiology and genetics of multiple system atrophy. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY , 38 (1) pp. 4-24. 10.1111/j.1365-2990.2011.01234.x.

Apaydin, H; Benbir, G; Lees, A; (2012) A stimulus-sensitive tic disorder characterized by echophenomena and coprolalia. Mov Disord , 27 (1) pp. 159-160. 10.1002/mds.23952.

Aviles-Olmos, I; Kefalopoulou, Z; Djamshidian, A; Limousin, P; Dickson, J; Lees, A; Foltynie, T; (2012) An open label, single site, 12 month, phase II, randomised controlled trial evaluating the safety and efficacy of Exendin-4 (Exenatide) in the treatment of patients with moderate severity Parkinson's disease. In: (pp. S109-S109).

Camargos, S; Lees, AJ; Singleton, A; Cardoso, F; (2012) DYT16: The original cases. Journal of Neurology, Neurosurgery and Psychiatry , 83 (10) pp. 1012-1014. 10.1136/jnnp-2012-302841.

Camargos, S; Lees, AJ; Singleton, A; Cardoso, F; (2012) DYT16: the original cases. J Neurol Neurosurg Psychiatry , 83 (10) pp. 1012-1014. 10.1136/jnnp-2012-302841.

Cardoso, F; Vale, T; Lees, A; (2012) Gowers' Queen Square Case Notes on Chorea. In:

Charlesworth, G; Gandhi, S; Bras, JM; Barker, RA; Burn, DJ; Chinnery, PF; Gentleman, SM; ... Wood, NW; + view all (2012) Tau acts as an independent genetic risk factor in pathologically proven PD. NEUROBIOLOGY OF AGING , 33 (4) 10.1016/j.neurobiolaging.2011.11.001.

Charlesworth, G; Gandhi, S; Bras, JM; Barker, RA; Burn, DJ; Chinnery, PF; Gentleman, SM; ... Wood, NW; + view all (2012) Tau acts as an independent genetic risk factor in pathologically proven PD. Neurobiology of Aging , 33 (4) 10.1016/j.neurobiolaging.2011.11.001.

Charlesworth, G; Gandhi, S; Bras, JM; Gentleman, SM; Guerreiro, R; Hardy, J; Holton, JL; ... Wood, NW; + view all (2012) First stage association analysis of neuropatholically proven PD confirms MAPT as an independent risk factor for PD. In: (pp. S450-S451).

Djamshidian, A; Lees, A; (2012) Impulsive compulsive behaviours in patients with Parkinson's disease treated with dopamine agonists. Focus on Parkinson's Disease , 23 (1) pp. 16-21.

Djamshidian, A; O'Sullivan, SS; Lees, A; Averbeck, BB; (2012) Effects of dopamine on sensitivity to social bias in Parkinson's disease. PLoS One , 7 (3) , Article e32889. 10.1371/journal.pone.0032889. Green open access
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Djamshidian, A; O'Sullivan, SS; Lees, AJ; Averbeck, BB; (2012) Effects of dopamine on sensitivity to social bias in Parkinson's disease. In: (pp. S268-S268).

Djamshidian, A; O'Sullivan, SS; Sanotsky, Y; Sharman, S; Matviyenko, Y; Foltynie, T; Michalczuk, R; ... Averbeck, BB; + view all (2012) Decision making, impulsivity, and addictions: Do Parkinson's disease patients jump to conclusions? MOVEMENT DISORDERS , 27 (9) pp. 1137-1145. 10.1002/mds.25105.

Djamshidian, A; O'Sullivan, SS; Sanotsky, Y; Sharman, S; Matviyenko, Y; Foltynie, T; Michalczuk, R; ... Averbeck, BB; + view all (2012) Decision making, impulsivity, and addictions: Do Parkinson's disease patients jump to conclusions? MOVEMENT DISORDERS , 27 (9) pp. 1137-1145. 10.1002/mds.25105.

Doherty, KM; Noyce, AJ; Silveira-Moriyama, L; Nisbet, A; Quinn, N; Lees, AJ; (2012) Familial camptocormia: from dystonia to myopathy. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY , 83 (3) pp. 350-351.

Doherty, KM; Silveira-Moriyama, L; Giladi, N; Bhatia, KP; Parton, M; Lees, AJ; (2012) Camptocormia: Don't forget muscle disease in the movement disorder clinic. Journal of Neurology , 259 (8) pp. 1752-1754. 10.1007/s00415-012-6448-z.

Doherty, KM; Silveira-Moriyama, L; Giladi, N; Bhatia, KP; Parton, M; Lees, AJ; (2012) Camptocormia: don't forget muscle disease in the movement disorder clinic. JOURNAL OF NEUROLOGY , 259 (8) pp. 1752-1754. 10.1007/s00415-012-6448-z.

Doherty, KM; Silveira-Moriyama, L; Nisbet, A; Noyce, A; Quinn, N; Parton, M; Lees, AJ; (2012) CAMPTOCORMIA: WHAT IS THE CAUSE? In:

Doherty, KM; Silveira-Moriyama, L; Parkkinen, L; Healy, D; Farrell, M; Mencacci, NE; Ahmed, Z; ... Holton, JL; + view all (2012) A clinicopathological study of parkin-linked parkinsonism - A study of 5 cases and comparison with Parkinson's disease. In: (pp. S453-S453).

Dubois, B; Tolosa, E; Katzenschlager, R; Emre, M; Lees, AJ; Schumann, G; Pourcher, E; ... Moline, ML; + view all (2012) Donepezil in Parkinson's disease dementia: A randomized, double-blind efficacy and safety study. MOVEMENT DISORDERS , 27 (10) pp. 1230-1238. 10.1002/mds.25098.

Eadie, MJ; Scott, AEM; Lees, AJ; Woodward, M; (2012) William Gowers: the never completed third edition of the 'Bible of Neurology'. Brain , 135 (Pt 10) pp. 3178-3188. 10.1093/brain/aws181.

Eatough, V; Shaw, K; Lees, A; (2012) Banking on brains: insights of brain donor relatives and friends from an experiential perspective. Psychol Health , 27 (11) pp. 1271-1290. 10.1080/08870446.2012.669480.

Gallagher, DA; Goetz, CG; Stebbins, G; Lees, AJ; Schrag, A; (2012) Validation of the MDS-UPDRS Part I for Nonmotor Symptoms in Parkinson's Disease. MOVEMENT DISORDERS , 27 (1) pp. 79-83. 10.1002/mds.23939.

Gallagher, DA; Goetz, CG; Stebbins, G; Lees, AJ; Schrag, A; (2012) Validation of the MDS-UPDRS Part I for nonmotor symptoms in Parkinson's disease. Movement Disorders , 27 (1) pp. 79-83. 10.1002/mds.23939.

Gardiner, AR; Bhatia, KP; Stamelou, M; Dale, RC; Kurian, MA; Schneider, SA; Wali, GM; ... Houlden, H; + view all (2012) PRRT2 gene mutations: from paroxysmal dyskinesia to episodic ataxia and hemiplegic migraine. Neurology , 79 (21) pp. 2115-2121. 10.1212/WNL.0b013e3182752c5a.

Gardiner, AR; Bhatia, KP; Stamelou, M; Dale, RC; Kurian, MA; Schneider, SA; Wali, GM; ... Houlden, H; + view all (2012) PRRT2 gene mutations From paroxysmal dyskinesia to episodic ataxia and hemiplegic migraine. NEUROLOGY , 79 (21) pp. 2115-2121.

Glass, P; Lees, A; Bacellar, A; Zijlmans, J; Katzenschlager, R; Silveira-Moriyama, L; (2012) Clinical Features of Vascular Parkinsonism in Pathologically Confirmed Cases. In: (Proceedings) 64th Annual Meeting of the American-Academy-of-Neurology (AAN). LIPPINCOTT WILLIAMS & WILKINS

Glass, PG; Lees, AJ; Bacellar, A; Zijlmans, J; Katzenschlager, R; Silveira-Moriyama, L; (2012) The clinical features of pathologically confirmed vascular Parkinsonism. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY , 83 (10) pp. 1027-1029. 10.1136/jnnp-2012-302828.

Glass, PG; Lees, AJ; Mathias, C; Mason, L; Best, C; Williams, DR; Katzenschlager, R; (2012) Olfaction in pathologically proven patients with multiple system atrophy. Movement Disorders , 27 (2) pp. 327-328. 10.1002/mds.23972.

Kara, E; Ling, H; Pittman, AM; Shaw, K; de Silva, R; Simone, R; Holton, JL; ... Revesz, T; + view all (2012) The MAPT p.A152T variant is a risk factor associated with tauopathies with atypical clinical and neuropathological features. Neurobioly of Aging , 33 (9) 2231.e7 - 2231.e14. 10.1016/j.neurobiolaging.2012.04.006. Green open access
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Kara, E; Xiromerisiou, G; Paudel, R; Revesz, T; Holton, J; Lees, A; Wood, N; ... Houlden, H; + view all (2012) Comprehensive genetic investigation of NBIA and complex dystonia-parkinsonism. In: (pp. S459-S459).

Keller, MF; Saad, M; Bras, J; Bettella, F; Nicolaou, N; Simon-Sanchez, J; Mittag, F; ... Nalls, MA; + view all (2012) Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease. HUMAN MOLECULAR GENETICS , 21 (22) pp. 4996-5009. 10.1093/hmg/dds335.

Kruer, MC; Paudel, R; Wagoner, W; Sanford, L; Kara, E; Gregory, A; Foltynie, T; ... Houlden, H; + view all (2012) Analysis of ATP13A2 in large neurodegeneration with brain iron accumulation (NBIA) and dystonia-parkinsonism cohorts. NEUROSCIENCE LETTERS , 523 (1) pp. 35-38. 10.1016/j.neulet.2012.06.036.

Kruer, MC; Paudel, R; Wagoner, W; Sanford, L; Kara, E; Gregory, A; Foltynie, T; ... Houlden, H; + view all (2012) Analysis of ATP13A2 in large neurodegeneration with brain iron accumulation (NBIA) and dystonia-parkinsonism cohorts. Neuroscience Letters , 523 (1) pp. 35-38. 10.1016/j.neulet.2012.06.036.

Lees, A; (2012) East meets west to provide the best for PD patients. Focus on Parkinson's Disease , 23 (1) 2-.

Lees, A; (2012) Two decades of evolving care with pump therapies - What have we learned? European Neurological Review , 7 (SUPPL.1) pp. 5-7.

Lees, A; Costa, R; Oliveira, C; Lopes, N; Nunes, T; Soares-da-Silva, P; (2012) Design of a double-blind, placebo-controlled, phase-III trial in patients with Parkinson's disease and end-of-dose motor fluctuations: opicapone superiority vs. placebo. In: (pp. p. 695).

Lees, A; Costa, R; Oliveira, C; Lopes, N; Nunes, T; Soares-da-Silva, P; (2012) The design of a double-blind, placebo-controlled, multi-national phase-III trial in patients with Parkinson's disease and end-of-dose motor fluctuations: Opicapone superiority vs. placebo. In: (pp. S127-S127).

Lees, A; Fahn, S; Eggert, KM; Jankovic, J; Lang, A; Micheli, F; Maral Mouradian, M; ... Kumar, D; + view all (2012) Perampanel, an AMPA antagonist, found to have no benefit in reducing "off" time in Parkinson's disease. Movement Disorders , 27 (2) pp. 284-288. 10.1002/mds.23983.

Lees, A; Fahn, S; Eggert, KM; Jankovic, J; Lang, A; Micheli, F; Mouradian, MM; ... Kumar, D; + view all (2012) Perampanel, an AMPA antagonist, found to have no benefit in reducing "off" time in Parkinson's disease. Mov Disord , 27 (2) pp. 284-288. 10.1002/mds.23983.

Lees, AJ; (2012) The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease. Journal of Neurology, Neurosurgery and Psychiatry , 83 (10) pp. 954-955. 10.1136/jnnp-2012-302969.

Lees, AJ; (2012) Impact Commentaries. A modern perspective on the top 100 cited JNNP papers of all time: The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease: accuracy of clinical diagnosis of idiopathic Parkinson's disease. J Neurol Neurosurg Psychiatry , 83 (10) pp. 954-955. 10.1136/jnnp-2012-302969.

Lees, AJ; Woodward, RMP; Scott, AEM; Eadie, MJ; (2012) W R Gowers 1895: two unpublished post-graduate lectures. Brain , 135 (Pt 10) pp. 3165-3177. 10.1093/brain/aws029.

Lin, MT; Cantuti-Castelvetri, I; Lees, AJ; Beal, MF; Simon, DK; (2012) Reply. Annals of Neurology , 72 (5) pp. 823-824. 10.1002/ana.23739.

Lin, MT; Cantuti-Castelvetri, I; Lees, AJ; Beal, MF; Simon, DK; (2012) Somatic Mitochondrial DNA Mutations and Parkinsonism Reply. ANNALS OF NEUROLOGY , 72 (5) pp. 823-824. 10.1002/ana.23739.

Lin, MT; Cantuti-Castelvetri, I; Zheng, K; Jackson, KE; Tan, YB; Arzberger, T; Lees, AJ; ... Simon, DK; + view all (2012) Somatic mitochondrial DNA mutations in early Parkinson and incidental Lewy body disease. Ann Neurol , 71 (6) pp. 850-854. 10.1002/ana.23568.

Ling, H; Massey, L; Lees, A; Brown, P; Day, B; (2012) Hypokinesia without decrement distinguishes progressive supranuclear palsy from Parkinson's disease. MOVEMENT DISORDERS , 27 S384 - S385.

Ling, H; Massey, L; Lees, A; Brown, P; Day, B; (2012) Hypokinesia without decrement distinguishes progressive supranuclear palsy from Parkinson's disease. MOVEMENT DISORDERS , 27 S384-S385.

Ling, H; Massey, LA; Lees, AJ; Brown, P; Day, BL; (2012) Hypokinesia without decrement distinguishes progressive supranuclear palsy from Parkinson's disease. BRAIN , 135 pp. 1141-1153. 10.1093/brain/aws038.

Ling, H; Massey, LA; Lees, AJ; Brown, P; Day, BL; (2012) Hypokinesia without decrement distinguishes progressive supranuclear palsy from Parkinson's disease. Brain , 135 (Pt 4) 1141 - 1153. 10.1093/brain/aws038.

Ling, H; Petrovic, I; Day, BL; Lees, AJ; (2012) Smoking-induced transient motor deterioration in a levodopa-treated patient with Parkinson's disease. JOURNAL OF NEUROLOGY , 259 (11) pp. 2419-2423. 10.1007/s00415-012-6515-5.

Ling, H; Petrovic, I; Day, BL; Lees, AJ; (2012) Smoking-induced transient motor deterioration in a levodopa-treated patient with Parkinson's disease. Journal of Neurology , 259 (11) pp. 2419-2423. 10.1007/s00415-012-6515-5.

Ling, H; de Silva, R; Courtney, R; Massey, L; Bajaj, N; Lowe, J; Holton, J; ... Revesz, T; + view all (2012) Clinicopathological study of progressive supranuclear palsy presenting with corticobasal syndrome. In: (pp. S384-S384).

Ling, H; de Silva, R; Massey, L; Bajaj, N; Lowe, J; Holton, J; Lees, A; (2012) Clinicopathological correlation of progressive supranuclear palsy presenting with corticobasal syndrome. In: (Proceedings) 16th Congress of the European-Federation-of-Neurological-Societies (EFNS). (pp. p. 290). WILEY-BLACKWELL

Loane, C; Politis, M; Wu, K; O'Sullivan, SS; Woodhead, Z; Lawrence, AD; Lees, AJ; (2012) Drug-cue elicited frontal and limbic dysfunction in Parkinson's disease patients with dopamine dysregulation syndrome. In: (pp. S245-S245).

Magdalinou, NK; Luk, C; Compta, Y; Marti, MJ; Lees, AJ; de Silva, R; (2012) Novel method for quantification of 3R-and 4R-tau isoforms in the cerebrospinal fluid of patients with atypical parkinsonian syndromes. In: (pp. S385-S386).

Massey, LA; Micallef, C; Paviour, DC; O'Sullivan, SS; Ling, H; Williams, DR; Kallis, C; ... Jäger, HR; + view all (2012) Conventional magnetic resonance imaging in confirmed progressive supranuclear palsy and multiple system atrophy. Movement Disorders , 27 (14) 1754 - 1762. 10.1002/mds.24968.

Massey, LA; Miranda, MA; Zrinzo, L; Al-Helli, O; Parkes, HG; Thornton, JS; So, P-W; ... Yousry, TA; + view all (2012) High resolution MR anatomy of the subthalamic nucleus: Imaging at 9.4 T with histological validation. NEUROIMAGE , 59 (3) pp. 2035-2044. 10.1016/j.neuroimage.2011.10.016.

Massey, LA; Miranda, MA; Zrinzo, L; Al-Helli, O; Parkes, HG; Thornton, JS; So, P-W; ... Yousry, TA; + view all (2012) High resolution MR anatomy of the subthalamic nucleus: imaging at 9.4 T with histological validation. Neuroimage , 59 (3) pp. 2035-2044. 10.1016/j.neuroimage.2011.10.016.

Morales-Briceno, H; Rodriguez-Violante, M; Cervantes-Arriaga, A; Irani, SR; Lees, AJ; Silveira-Moriyama, L; (2012) Opsoclonus Myoclonus Syndrome associated with GQ1b Antibodies. MOVEMENT DISORDERS , 27 (13) pp. 1615-1616. 10.1002/mds.25169.

Moscovich, M; Munhoz, R; Teive, H; Raskin, S; Liu, J; McFarland, K; Ashizawa, T; ... Silveira-Moriyama, L; + view all (2012) To Investigate Olfactory Impairment in Cerebellar Ataxia. In:

Moscovich, M; Munhoz, RP; Teive, HA; Raskin, S; Carvalho, MDJ; Barbosa, ER; Ranvaud, R; ... Silveira-Moriyama, L; + view all (2012) Olfactory impairment in familial ataxias. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY , 83 (10) pp. 970-974. 10.1136/jnnp-2012-302770.

Moscovich, M; Munhoz, RP; Teive, HA; Raskin, S; De Carvalho, MJ; Barbosa, ER; Ranvaud, R; ... Silveira-Moriyama, L; + view all (2012) Olfactory impairment in familial ataxias. Journal of Neurology, Neurosurgery and Psychiatry , 83 (10) pp. 970-974. 10.1136/jnnp-2012-302770.

Noyce, A; Bestwick, J; Hawkes, CH; Knowles, CH; Hardy, J; Lees, AJ; Silveira-Moriyama, L; ... Schrag, A; + view all (2012) AN ALGORITHM TO IDENTIFY INDIVIDUALS AT HIGH-RISK OF PARKINSON'S DISEASE IN THE COMMUNITY. In: (Proceedings) Annual Meeting of the Association-of-British-Neurologists. BMJ PUBLISHING GROUP

Noyce, A; Bestwick, J; Hawkes, CH; Knowles, CH; Hardy, J; Lees, AJ; Silveira-Moriyama, L; ... Schrag, A; + view all (2012) AN ALGORITHM TO IDENTIFY INDIVIDUALS AT HIGH-RISK OF PARKINSON'S DISEASE IN THE COMMUNITY. In:

Noyce, A; Silveira-Moriyama, L; Lees, AJ; Schrag, A; Bestwick, J; Hawkes, CH; Giovannoni, G; ... Knowles, CH; + view all (2012) A PILOT STUDY OF AN ALGORITHM DESIGNED TO IDENTIFY PARKINSON'S DISEASE IN THE EARLY, NON-MOTOR PHASE. In: (Proceedings) Annual Meeting of the Association-of-British-Neurologists. BMJ PUBLISHING GROUP

Noyce, A; Silveira-Moriyama, L; Lees, AJ; Schrag, A; Bestwick, J; Hawkes, CH; Giovannoni, G; ... Knowles, CH; + view all (2012) A PILOT STUDY OF AN ALGORITHM DESIGNED TO IDENTIFY PARKINSON'S DISEASE IN THE EARLY, NON-MOTOR PHASE. In:

Noyce, A; Treacy, C; Budu, C; Fearnley, J; Lees, AJ; Giovannoni, G; (2012) THE NEW BRADYKINESIA AKINESIA INCOORDINATION (BRAIN) TEST: AN ONLINE TEST OF UPPER LIMB MOVEMENT. In:

Noyce, AJ; Bestwick, J; Silveira-Moriyama, L; Hawkes, CH; Giovannoni, G; Lees, AJ; Schrag, A; (2012) Risk factors and early non-motor features for Parkinson's disease: A systematic review and meta-analysis. In: (pp. S4-S4).

Noyce, AJ; Bestwick, JP; Silveira-Moriyama, L; Hawkes, CH; Giovannoni, G; Lees, AJ; Schrag, A; (2012) Meta-Analysis of Early Nonmotor Features and Risk Factors for Parkinson Disease. ANNALS OF NEUROLOGY , 72 (6) pp. 893-901. 10.1002/ana.23687.

Noyce, AJ; Bestwick, JP; Silveira-Moriyama, L; Hawkes, CH; Giovannoni, G; Lees, AJ; Schrag, A; (2012) Meta-analysis of early nonmotor features and risk factors for Parkinson disease. Annals of Neurology , 72 (6) pp. 893-901. 10.1002/ana.23687.

Noyce, AJ; Silveira-Moriyama, L; Gilpin, P; Ling, H; Howard, R; Lees, AJ; (2012) Severe dysphagia as a presentation of Parkinson's disease. MOVEMENT DISORDERS , 27 (3) pp. 457-458. 10.1002/mds.24006.

Noyce, AJ; Treacy, C; Budu, C; Fearnley, J; Lees, AJ; Giovannoni, G; (2012) The New Bradykinesia Akinesia Incoordination (BRAIN) Test: Preliminary Data from an Online Test of Upper Limb Movement. MOVEMENT DISORDERS , 27 (1) pp. 157-158. 10.1002/mds.23947.

O'Sullivan, SS; Cheshire, P; Djamshidian, A; Bertram, K; Williams, DR; Lees, AJ; Foltynie, T; (2012) Is the brain-derived neurotrophic factor (BDNF) Val66Met genetic polymorphism associated with impulsive-compulsive behaviours in Parkinson's disease? In: (pp. S464-S465).

Ozawa, T; Revesz, T; Paviour, D; Lees, AJ; Quinn, N; Tada, M; Kakita, A; ... Holton, JL; + view all (2012) Difference in MSA Phenotype Distribution Between Populations: Genetics or Environment? JOURNAL OF PARKINSONS DISEASE , 2 (1) pp. 7-18. 10.3233/JPD-2012-11056.

Paisan-Ruiz, C; Li, A; Schneider, SA; Holton, JL; Johnson, R; Kidd, D; Chataway, J; ... Houlden, H; + view all (2012) Widespread Lewy body and tau accumulation in childhood and adult onset dystonia-parkinsonism cases with PLA2G6 mutations. NEUROBIOLOGY OF AGING , 33 (4) pp. 814-823. 10.1016/j.neurobiolaging.2010.05.009.

Petrovic, IN; Ling, H; Asi, Y; Ahmed, Z; Kukkle, PL; Hazrati, L-N; Lang, AE; ... Lees, AJ; + view all (2012) Multiple system atrophy-parkinsonism with slow progression and prolonged survival: A diagnostic catch. MOVEMENT DISORDERS , 27 (9) pp. 1184-1188. 10.1002/mds.25115.

Pittman, A; Mencacci, N; Sheerin, U; Charlesworth, G; Deborah, H; Haworth, A; Sweeney, M; ... Lees, A; + view all (2012) A comprehensive diagnostic test for familial and early onset Parkinson's disease based on next-generation sequencing. In: (Proceedings) British Human Genetics Conference. (pp. S122-S122). BMJ PUBLISHING GROUP

Politis, M; Loane, C; Wu, K; O'Sullivan, S; Woodhead, Z; Kiferle, L; Lawrence, AD; ... Piccini, P; + view all (2012) Neural correlates of hypersexuality in Parkinson's disease. In: (pp. S250-S250).

Sanotsky, Y; Selikhova, M; Fedorishin, L; Matvienko, Y; Komnatska, I; Grey, H; Tripoliti, E; (2012) Update on ephedrone induced parkinsonism with dystonia: Four year follow up. In: (pp. S393-S394).

Schottlaender, LV; Mencacci, N; Koepp, M; Hanna, M; Hardy, J; Lees, AJ; Houlden, H; (2012) Interesting clinical features associated with mutations in the SLC20A2 gene. In: (Proceedings) 16th Congress of the European-Federation-of-Neurological-Societies (EFNS). (pp. p. 40). WILEY-BLACKWELL

Schottlaender, LV; Sailer, A; Tucci, A; Mok, K; Ling, H; Plagnol, V; Quinn, N; ... Houlden, H; + view all (2012) Exome sequencing in familial multiple system atrophy. In: (pp. S468-S468).

Sheerin, U-M; Charlesworth, G; Bras, J; Guerreiro, R; Bhatia, K; Foltynie, T; Limousin, P; ... Wood, N; + view all (2012) Screening for VPS35 mutations in Parkinson's disease. NEUROBIOLOGY OF AGING , 33 (4) 10.1016/j.neurobiolaging.2011.10.032.

Sheerin, UM; Charlesworth, G; Bras, J; Guerreiro, R; Bhatia, K; Foltynie, T; Limousin, P; ... Wood, N; + view all (2012) Screening for VPS35 mutations in Parkinson's disease. Neurobiology of Aging , 33 (4) 10.1016/j.neurobiolaging.2011.10.032.

Silveira-Moriyama, L; Kingsbury, A; Ayling, H; Holton, JL; Sterlacci, W; Petrie, A; Rajan, S; ... Lees, AJ; + view all (2012) Availability of olfactory bulb and olfactory tract in brain specimens in a brain bank. In: (pp. S518-S518).

Silveira-Moriyama, L; Lees, AJ; (2012) Tricks of the trade. Arquivos de Neuro-Psiquiatria , 70 (4) 245-. Gold open access

Stockner, H; Schwingenschuh, P; Djamshidian, A; Silveira-Moriyama, L; Katschnig, P; Seppi, K; Dickson, J; ... Bhatia, KP; + view all (2012) Is transcranial sonography useful to distinguish scans without evidence of dopaminergic deficit patients from Parkinson's disease? Movement Disorders , 27 (9) 1182 - 1185. 10.1002/mds.25102. Green open access
file

Taba, P; Lees, AJ; Stern, G; (2012) Erich Harnack and apomorphine: An historical insight. In: (pp. S88-S88).

Teive, HAG; Germiniani, FMB; Munhoz, RP; Lees, AJ; (2012) Letters from Dom Pedro II to professor Brown-Séquard: Imperial correspondence and neurophysiology. Arquivos de Neuro-Psiquiatria , 70 (8) pp. 633-636. 10.1590/S0004-282X2012000800014. Gold open access

Teive, HAG; Germiniani, FMB; Munhoz, RP; Lees, AJ; (2012) Letters from Dom Pedro II to professor Brown-Séquard: imperial correspondence and neurophysiology. Arq Neuropsiquiatr , 70 (8) pp. 633-636. Gold open access

Vale, TC; Lees, A; Cardoso, F; (2012) Gower's Queen Square case notes on chorea. In: (pp. S88-S88).

Xiromerisiou, G; Houlden, H; Sailer, A; Silveira-Moriyama, L; Hardy, J; Lees, AJ; (2012) Identical twins with Leucine rich repeat kinase type 2 mutations discordant for Parkinson's disease. MOVEMENT DISORDERS , 27 (10) pp. 1323-1324. 10.1002/mds.24924.

Xiromerisiou, G; Houlden, H; Scarmeas, N; Stamelou, M; Kara, E; Hardy, J; Lees, A; ... Bhatia, K; + view all (2012) THAP1 mutations and dystonia phenotypes: A metanalysis, genotype phenotype correlations and identification of novel mutations. In: (pp. S370-S370).

Xiromerisiou, G; Houlden, H; Scarmeas, N; Stamelou, M; Kara, E; Hardy, J; Lees, AJ; ... Bhatia, KP; + view all (2012) THAP1 mutations and dystonia phenotypes: Genotype phenotype correlations. MOVEMENT DISORDERS , 27 (10) pp. 1290-1294. 10.1002/mds.25146.

Xiromerisiou, G; Houlden, H; Scarmeas, N; Stamelou, M; Kara, E; Hardy, J; Lees, AJ; ... Bhatia, KP; + view all (2012) THAP1 mutations and dystonia phenotypes: Genotype phenotype correlations. Movement Disorders , 27 (10) pp. 1290-1294. 10.1002/mds.25146.

2011

Ahmed, Z; Asi, YT; Lees, AJ; Revesz, T; Holton, JL; (2011) Investigating the role of oligodendroglial precursor cells in multiple system atrophy and progressive supranuclear palsy. In: NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. (pp. 21 - 21). WILEY-BLACKWELL PUBLISHING, INC

Ahmed, Z; Doherty, K; Silveira-Moriyama, L; Bandopadhyay, R; Lashley, T; Mamais, A; Hondhamuni, G; ... Revesz, T; + view all (2011) GLOBULAR GLIAL TAUOPATHIES: AN EMERGING GROUP OF 4-REPEAT TAUOPATHIES PRESENTING WITH MOTOR NEURON DISEASE OR FRONTOTEMPORAL DEMENTIA. In: EUROPEAN JOURNAL OF NEUROLOGY. (pp. 22 - 22). WILEY-BLACKWELL

Ahmed, Z; Doherty, K; Silveira-Moriyama, L; Bandopadhyay, R; Lashley, T; Newcombe, J; O'sullivan, SS; ... Revesz, T; + view all (2011) Clinicopathological comparison of globular glial tauopathies presenting with motor neuron disease or frontotemporal dementia: An emerging group of 4-repeat tauopathies. In: (pp. S328-S329).

Ahmed, Z; Doherty, KM; Silveira-Moriyama, L; Bandopadhyay, R; Lashley, T; Mamais, A; Hondhamuni, G; ... Revesz, T; + view all (2011) Globular glial tauopathies (GGT) presenting with motor neuron disease or frontotemporal dementia: an emerging group of 4-repeat tauopathies. ACTA NEUROPATHOL , 122 (4) 415 - 428. 10.1007/s00401-011-0857-4.

Alarcón, F; Dueñas, G; Lees, A; (2011) Encephalitis lethargica due to Epstein-Barr virus infection. Mov Disord , 26 (11) pp. 2132-2134. 10.1002/mds.23772.

Anaya, F; Lees, A; de Silva, R; (2011) TAU GENE PROMOTER rs242557 AND ALLELE-SPECIFIC PROTEIN BINDING. TRANSLATIONAL NEUROSCIENCE , 2 (2) pp. 176-205. 10.2478/s13380-011-0021-6.

Anzak, A; Tan, HL; Pogosyan, A; Djamshidian, A; Ling, HL; Lees, A; Brown, P; (2011) Improvements in rate of development and magnitude of force with intense auditory stimuli in patients with Parkinson's disease. EUR J NEUROSCI , 34 (1) 124 - 132. 10.1111/j.1460-9568.2011.07735.x.

Bandopadhyay, R; Mamais, A; Lashley, T; Griffiths, C; Goswami, N; Holton, JL; Revesz, T; (2011) The role of 4E-BP1, a putative LRRK2 interactor in the pathology of IPD and in G2019S LRRK2 mutation cases. In: NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. (pp. 21 - 21). WILEY-BLACKWELL PUBLISHING, INC

Brelstaff, J; Lashley, T; Holton, JL; Lees, AJ; Rossor, MN; Bandopadhyay, R; Revesz, T; (2011) Transportin1: a marker of FTLD-FUS. ACTA NEUROPATHOL , 122 (5) 591 - 600. 10.1007/s00401-011-0863-6.

Brooks, JA; Houlden, H; Melchers, A; Islam, AJ; Ding, J; Li, A; Paudel, R; ... Scholz, SW; + view all (2011) Mutational analysis of parkin and PINK1 in multiple system atrophy. Neurobiology of Aging , 32 (3) 10.1016/j.neurobiolaging.2009.11.020.

Brooks, JA; Houlden, H; Melchers, A; Islam, AJ; Ding, JH; Li, A; Paudel, R; ... Scholz, SW; + view all (2011) Mutational analysis of parkin and PINK1 in multiple system atrophy. NEUROBIOL AGING , 32 (3) , Article 548.e5. 10.1016/j.neurobiolaging.2009.11.020.

Camargos, ST; Gurgel-Giannetti, J; Lees, A; Hardy, J; Singleton, A; Cardoso, F; (2011) Low prevalence of PANK2 mutations in Brazilian patients with early onset generalised dystonia and basal ganglia abnormalities on MRI. J Neurol Neurosurg Psychiatry , 82 (9) pp. 1059-1060. 10.1136/jnnp.2009.200808.

Compta, Y; Parkkinen, L; O'Sullivan, SS; Vandrovcova, J; Holton, JL; Collins, C; Lashley, T; ... Revesz, T; + view all (2011) Lewy- and Alzheimer-type pathologies in Parkinson's disease dementia: which is more important? BRAIN , 134 1493 - 1505. 10.1093/brain/awr031.

Coop, M; (2011) Untitled. GEOTECHNIQUE LETTERS , 1 p. 1. 10.1680/geolett.11.00013.

Djamshidian, A; Averbeck, BB; Lees, AJ; O'Sullivan, SS; (2011) Clinical aspects of impulsive compulsive behaviours in Parkinson's disease. JOURNAL OF THE NEUROLOGICAL SCIENCES , 310 (1-2) pp. 183-188. 10.1016/j.jns.2011.07.031.

Djamshidian, A; Cardoso, F; Grosset, D; Bowden-Jones, H; Lees, AJ; (2011) Pathological Gambling in Parkinson's Disease-A Review of the Literature. MOVEMENT DISORD , 26 (11) 1976 - 1984. 10.1002/mds.23821.

Djamshidian, A; O apos Sullivan, SS; Doherty, K; Lees, AJ; Averbeck, BB; (2011) Altruistic punishment in patients with Parkinson's disease with and without impulsive behaviour. Neuropsychologia , 49 (1) pp. 103-107. 10.1016/j.neuropsychologia.2010.10.012.

Djamshidian, A; O'Sullivan, SS; Doherty, K; Lees, AJ; Averbeck, BB; (2011) Altruistic punishment in patients with Parkinson's disease with and without impulsive behaviour. NEUROPSYCHOLOGIA , 49 (1) 103 - 107. 10.1016/j.neuropsychologia.2010.10.012.

Djamshidian, A; O'Sullivan, SS; Lees, A; Averbeck, BB; (2011) Stroop test performance in impulsive and non impulsive patients with Parkinson's disease. PARKINSONISM RELAT D , 17 (3) 212 - 214. 10.1016/j.parkreldis.2010.12.014.

Djamshidian, A; O'Sullivan, SS; Papadopoulos, A; Bassett, P; Shaw, K; Averbeck, BB; Lees, A; (2011) Salivary cortisol levels in Parkinson's disease and its correlation to risk behaviour. J NEUROL NEUROSUR PS , 82 (10) 1107 - 1111. 10.1136/jnnp.2011.245746. Gold open access

Djamshidian, A; O'Sullivan, SS; Wittmann, BC; Lees, AJ; Averbeck, BB; (2011) Novelty seeking behaviour in Parkinson's disease. Neuropsychologia , 49 (9) pp. 2483-2488. 10.1016/j.neuropsychologia.2011.04.026.

Djamshidian, A; O'Sullivan, SS; Wittmann, BC; Lees, AJ; Averbeck, BB; (2011) Novelty seeking behaviour in Parkinson's disease. NEUROPSYCHOLOGIA , 49 (9) 2483 - 2488. 10.1016/j.neuropsychologia.2011.04.026.

Djamshidian, A; O'Sullivan, SS; Wittmann, BC; Lees, AJ; Averbeck, BB; (2011) Novelty seeking behaviour in Parkinson's disease. Neuropsychologia

Djamshidian, A; O'sullivan, SS; Papadopoulos, A; Bassett, P; Shaw, K; Averbeck, BB; Lees, AJ; (2011) Salivary cortisol levels in Parkinson's disease and its correlation to risk behaviour. In: (pp. S101-S101).

Doherty, KM; Silveira-Moriyama, L; Davagnanam, I; Molloy, S; Lees, AJ; (2011) Spinal changes underlying postural deformity in Parkinson's disease. In: (pp. S240-S241).

Fabbrini, G; Merello, M; Evans, AH; Lees, AJ; Holton, J; Williams, DR; (2011) Progressive Parkinsonism, Oculomotor Abnormalities and Autonomic Dysfunction: Clinicopathological Case. MOVEMENT DISORD , 26 (3) 424 - 429. 10.1002/mds.23302.

Fabbrini, G; Merello, M; Evans, AH; Lees, AJ; Holton, J; Williams, DR; (2011) Progressive parkinsonism, oculomotor abnormalities and autonomic dysfunction: Clinicopathological case. Movement Disorders , 26 (3) pp. 424-429. 10.1002/mds.23302.

Gallagher, DA; Parkkinen, L; O'Sullivan, SS; Spratt, A; Shah, A; Davey, CC; Bremner, FD; ... Schrag, A; + view all (2011) Testing an aetiological model of visual hallucinations in Parkinson's disease. BRAIN , 134 3299 - 3309. 10.1093/brain/awr225.

Grosset, DG; Cardoso, F; Lees, A; (2011) Dopamine agonists vs levodopa in impulse control disorders. Arch Neurol , 68 (4) pp. 544-545. 10.1001/archneurol.2011.41.

Halliday, G; Lees, A; Stern, M; (2011) Milestones in Parkinson's Disease-Clinical and Pathologic Features. MOVEMENT DISORDERS , 26 (6) pp. 1015-1021. 10.1002/mds.23669.

Hoglinger, GU; Melhem, NM; Dickson, DW; Sleiman, PMA; Wang, LS; Klei, L; Rademakers, R; ... PSP Genetics Study Grp, ; + view all (2011) Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy. NAT GENET , 43 (7) 699 - U125. 10.1038/ng.859.

Holton, JL; Lees, AJ; Revesz, T; (2011) Multiple System Atrophy. pp. 242-252. 10.1002/9781444341256.ch24.

Kearney, SJ; Yip, H; Lees, AJ; Revesz, T; Silveira-Moriyama, L; (2011) Parkinsonism without pathological explanation. In: (pp. S339-S339).

Lashley, T; Rohrer, JD; Bandopadhyay, R; Fry, C; Ahmed, Z; Isaacs, AM; Brelstaff, JH; ... Revesz, T; + view all (2011) A comparative clinical, pathological, biochemical and genetic study of fused in sarcoma proteinopathies. BRAIN , 134 2548 - 2564. 10.1093/brain/awr160.

Lees, A; (2011) The Hurricane Port. [Book]. Mainstream Digital

Lees, AJ; (2011) CAN THERAPY MODIFY NATURAL EVOLUTION OF PARKINSON'S DISEASE? - CONTRA. In: (pp. p. 17).

Lees, AJ; (2011) THE NOSOLOGY OF PARKINSON'S DISEASE. In: (pp. p. 638).

Lindgren, HS; Rylander, D; Iderberg, H; Andersson, M; O'Sullivan, SS; Williams, DR; Lees, AJ; (2011) Putaminal upregulation of FosB/ΔFosB-like immunoreactivity in Parkinson's disease patients with Dyskinesia. Journal of Parkinson's Disease , 1 (4) pp. 347-357. 10.3233/JPD-2011-11068.

Lindgren, HS; Rylander, D; Iderberg, H; Andersson, M; O'Sullivan, SS; Williams, DR; Lees, AJ; (2011) Putaminal Upregulation of FosB/Delta FosB-Like Immunoreactivity in Parkinson's Disease Patients with Dyskinesia. JOURNAL OF PARKINSONS DISEASE , 1 (4) pp. 347-357. 10.3233/JPD-2011-11068.

Ling, H; Braschinsky, M; Taba, P; Luus, SM; Doherty, K; Hotter, A; Poewe, W; (2011) Decades of Delayed Diagnosis in 4 Levodopa-Responsive Young-Onset Monogenetic Parkinsonism Patients. MOVEMENT DISORD , 26 (7) 1337 - 1340. 10.1002/mds.23563.

Ling, H; Braschinsky, M; Taba, P; Lüüs, S-M; Doherty, K; Hotter, A; Poewe, W; (2011) Decades of delayed diagnosis in 4 levodopa-responsive young-onset monogenetic parkinsonism patients. Movement Disorders

Ling, H; Braschinsky, M; Taba, P; Lüüs, SM; Doherty, K; Hotter, A; Poewe, W; (2011) Decades of delayed diagnosis in 4 levodopa-responsive young-onset monogenetic parkinsonism patients. Movement Disorders , 26 (7) pp. 1337-1340. 10.1002/mds.23563.

Ling, H; Massey, L; Lunn, M; Lees, A; (2011) A rare cause of L-Dopa responsive parkinsonism: The answer lies in the eyes. In: (pp. S341-S341).

Ling, H; Polke, JM; Sweeney, MG; Haworth, A; Sandford, CA; Heales, SJR; Wood, NW; ... Lees, AJ; + view all (2011) An intragenic duplication in guanosine triphosphate cyclohydrolase-1 gene in a dopa-responsive dystonia family. Movement Disorders , 26 (5) pp. 905-909. 10.1002/mds.23593.

Ling, H; Polke, JM; Sweeney, MG; Haworth, A; Sandford, CA; Heales, SJR; Wood, NW; ... Lees, AJ; + view all (2011) An Intragenic Duplication in Guanosine Triphosphate Cyclohydrolase-1 Gene in a Dopa-Responsive Dystonia Family. MOVEMENT DISORD , 26 (5) 905 - 909. 10.1002/mds.23593.

Nalls, MA; Plagnol, V; Hernandez, DG; Sharma, M; Sheerin, UM; Saad, M; Simon-Sanchez, J; ... Wellcome Trust Case-Control Consor, ; + view all (2011) Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies. LANCET , 377 (9766) 641 - 649. 10.1016/S0140-6736(10)62345-8.

Noyce, AJ; Gilpin, P; Howard, R; Lees, AJ; Silviera-Moriyama, L; (2011) Severe dysphagia preceding Parkinson's disease. In: (pp. S195-S196).

O'Sullivan, SS; Johnson, M; Williams, DR; Revesz, T; Holton, JL; Lees, AJ; Perry, EK; (2011) The effect of drug treatment on neurogenesis in Parkinson's disease. Movement Disorders , 26 (1) pp. 45-50. 10.1002/mds.23340.

O'Sullivan, SS; Johnson, M; Williams, DR; Revesz, T; Holton, JL; Lees, AJ; Perry, EK; (2011) The Effect of Drug Treatment on Neurogenesis in Parkinson's Disease. MOVEMENT DISORD , 26 (1) 45 - 50. 10.1002/23340.

O'Sullivan, SS; Johnson, M; Williams, DR; Revesz, T; Holton, JL; Lees, AJ; Perry, EK; (2011) The effect of drug treatment on neurogenesis in Parkinson's disease. Mov Disord , 26 (1) pp. 45-50. 10.1002/mds.23340.

O'Sullivan, SS; Lees, AJ; (2011) Dopamine Dysregulation Syndrome. pp. 202-214. 10.1002/9781444397970.ch19.

O'Sullivan, SS; Loane, CM; Lawrence, AD; Evans, AH; Piccini, P; Lees, AJ; (2011) Sleep disturbance and impulsive-compulsive behaviours in Parkinson's disease. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY , 82 (6) pp. 620-622. 10.1136/jnnp.2009.186874.

O'Sullivan, SS; Wu, K; Politis, M; Lawrence, AD; Evans, AH; Bose, SK; Djamshidian, A; ... Piccini, P; + view all (2011) Cue-induced striatal dopamine release in Parkinson's disease-associated impulsive-compulsive behaviours. Brain , 134 (4) pp. 969-978. 10.1093/brain/awr003.

O'Sullivan, SS; Wu, K; Politis, M; Lawrence, AD; Evans, AH; Bose, SK; Djamshidian, A; ... Piccini, P; + view all (2011) Cue-induced striatal dopamine release in Parkinson's disease-associated impulsive-compulsive behaviours. BRAIN , 134 969 - 978. 10.1093/brain/awr003.