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Proton beam therapy
Proton beam radiotherapy at UCL
UCLH is hoping to host a cutting edge new proton therapy centre which aims to begin to treat patients in 2015. Proton therapy is an advanced radiotherapy technique which is able to target a tumour while minimising radiation dose to surrounding tissues. It is particularly well suited for difficult to treat tumours (e.g. head and neck, and spine) and where is is particularly important to reduce dose to other organs (e.g. in children).
Proton Radiography is an imaging technique based on the measurement of the energy lost by particles after their interaction with a target. The technique will be employed as a quality control tool in proton radiation therapy (PRT) to a) verify the correct positioning of the patient and b) control the maximum depth that protons will reach within the tissue (proton range), potentially improving the accuracy in PRT by providing spatial information of the geometrical conditions encountered during the treatment. In this project, the use of C-MOS Active Pixel Sensors (APS) is proposed. More >>
In vivo proton dosimetry
We are examining methods for in vivo dosimetry, which will allow us to map the location of the interaction of the protons in the patient.
Modelling of proton radiotherapy
The transport of protons through tissue is generally modelled using Monte Carlo methods. We are using the GEANT4 Monte Carlo code to simulate the energy deposition and emission from the interaction of protons with tissue.