2009 IoN News Archive
- Grant for research into new epilepsy treatments
- Professor Martin Rossor has been recognised by the The Alzheimer's Association
- Drug discovery collaboration on inclusion body myositis
- PDS awards Training Fellowship to Institute of Neurology researcher to understand how the brain controls Parkinson’s symptoms
- Alan Thompson to lead UCL Partners Neurological Disorders theme
- World MS Day - Wednesday 27th May - Global initiative to highlight Multiple Sclerosis
- Queen Square leads on new UK recommendations for bladder management which can dramatically improve quality of life in Multiple Sclerosis
- John Hardy most-cited Alzheimer's disease researcher in the UK
- Prestigious awards for Institute researchers
- Drug study offers hope for Alzheimer’s treatment
- Brain activity predicts our choices
- Professor George du Boulay CBE, FRCR, FRCP
- Brain awareness week: the impact of UCL research
- Parkinson's-linked mutation makes neurons vulnerable to calcium-induced death
- Second round of NIHR Senior Investigators announced
- 'Mind-Reading' Experiment Highlights How Brain Records Memories
- Anti-malaria drug does not appear to help with human prion diseases.
- UCL Partners is one of UK’s first Academic Health Science Centres
- "Opening doors for patients with MS"
- Are we as decisive as we think?
- "Magnets stop the nightmare of tinnitus, researchers say."
- Prestigious award for Professor Hugh Bostock
- Untangling the Brain
- Young UCL Investigator Award in neuroimaging techniques
- Brain disease "resistance gene" could offer insights into CJD
- Neurology: A Queen Square Textbook
- Headache: annual evidence update
- Roads closed for powerful MRI scanner delivery
- Long-term risks lower for surgical treatment of carotid stenosis
- Memorandum of collaboration signed
- Professor John Hardy joins the ranks of science greats
- Drug study offers hope for Alzheimer's treatment
- Prestigious award for Professor David Miller
- Magnets stop the nightmare of tinnitus, researchers say.
- Brain activity predicts our choices
- Jon Driver Award
- Professor Sander named recipient of the American Epilepsy Society 2009 Clinical Science Award
- Study highlights effect of brain waves on human behaviour
- New podcast describes the significance and impact of highly cited paper
- NIH Grant for research into inherited neuropathies
- How the brain knows a dog is a dog: concept acquisition in the human brain
- Prof Elizabeth Fisher elected member of the European Molecular Biology Organization (EMBO)
- Locating literacy in the brain
- Dopamine enhances expectation of pleasure in humans
- Queen Square scientists question memory theory
- IoN scientist to front Alzheimer’s Research Trust national appeal
- New doors open to the understanding of the origin of brain tumours
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Queen Square scientists question memory theory
15 November 2009
The long-held theory that our brains use different mechanisms for forming long-term and short-term memories has been challenged by new research from UCL, published in PNAS.
Neuroscientists formed this theory based on observation of patients with amnesia, a condition that severely disrupts the ability to form long-lasting memories. Typically, amnesia is caused by injury to the hippocampi, a pair of brain structures located in the depth of the temporal lobes.
The team studied patients with a specific form of epilepsy called ‘temporal lobe epilepsy with bilateral hippocampal sclerosis’, which leads to marked dysfunction of the hippocampi. They asked the patients to try and memorise photographic images depicting normal scenes, for example chairs and a table in a living-room. Their memory of the image was tested and brain activity recorded using MEG (magnetoencephalography) after a short interval of just five seconds, or a long interval of 60 minutes.
Nathan Cashdollar, (Department of Clinical and Experimental Epilepsy) first author of the paper, said: “Recent behavioural observations had already begun challenging the classical distinction between long-term and short-term memory which has persisted for nearly half a century. However, this is the first functional and anatomical evidence showing which mechanisms are shared between short-term and long-term memory and which are independent.”
“They also highlight that patients with impaired long-term memory have a short-term memory burden to carry in their daily life as well.”
More >> UCL News
Reference >> Cashdollar,N., Malecki,U., Rugg-Gunn,F.J., Duncan,J.S., Lavie,N., Duzel,E. ‘Hippocampus dependent and independent theta-networks of active maintenance’ is published in the Proceedings of the National Academy of Sciences of the United States of America (PNAS) Monday 9th November online early edition.