- Welcome to ChemiBank
UCL ChemiBank is a new resource for identifying small molecule ligands for proteins.
The facility stores complete chemical libraries and compound collections in a controlled environment. A range of chemoinformatic and biological assay services is provided for early drug discovery projects and to further existing projects in lead selection and library design.
Chemibank's main aim is to enable small molecule ligand discovery for UCL's research community.
Our chemical libraries include:
• 30000 diverse compounds
• 5000 pharmacologically active compounds
• 500 fragments
• 300 channel selective compounds
•>200 specialist compounds from the UCL Department of Chemistry
UCL ChemiBank's main focus is the early discovery of hits using the tools of virtual screening such as docking, pharmacophore filtering and de novo fragment building. To accompany the chemoinformatics, UCL ChemiBank can provide a number of other services such as:
•Biological assay development and screening
•sequence searching, alignments, binding site analysis
•G-protein coupled receptor modelling
•Electrostatics, molecular dynamics
•property profiling, quantitative structure-activity relationships
From virtual to real discovery, the UCL ChemiBank facility will prepare chemical libraries and develop the biological assays for compound screening. UCL Chemibank, which is located in the Wolfson Institute for Biomedical Research, is available as a resource for UCL and affiliated institutes.
Chemibank was established with funding from MRC and UCL business. Support services are provided by The Wolfson Institute for Biomedical Research, scientific support.
Further information can be found at the Wolfson Institute for Biomedical Research (WIBR), UCL website alternatively you can email Dr. Edith Chan: edith.chan @ ucl.ac.uk (remove spaces).
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Chemibank will provide assay services to test compound activity as well as utilising existing collaborations for pharmacological, biochemical and electrophysiological testing.
LOGIN to Chemibank.
Registered Chemibank users can upload, edit and perform complete searches on the compound collections.
REGISTER to be a Chemibank User
You will need an active UCL login, a head of lab or supervisor permission, or be a Principal Investigator.
SEARCH Chemibank for structures. Limited search for non-registered guests.
For full search you need to login.
Advanced SEARCH of Chemibank for registered users.
UPLOAD new structures to Chemibank.
You must be logged in to upload to Chemibank
HELP for adding new structures to Chemibank.
The physical process of adding new compounds to Chemibank, weighing out, labelling etc
We would like to thank Peter Ertl, Novartis for permission to use the JME Editor.