1. Beaton L, Tregidgo HFJ, Znati SA, Forsyth S, Clarkson MJ, Bandula S, Chouhan M, Lowe HL, Zaw Thin M, Hague J, Sharma D, Pollok JM, Davidson BR, Raja J, Munneke G, Stuckey DJ, Bascal ZA, Wilde PE, Cooper S, Ryan S, Czuczman P, Boucher E, Hartley JA, Lewis AL, Jansen M, Meyer T, Sharma RA. VEROnA Protocol: A Pilot, Open-Label, Single-Arm, Phase 0, Window-of-Opportunity Study of Vandetanib-Eluting Radiopaque Embolic Beads (BTG-002814) in Patients With Resectable Liver Malignancies. JMIR Res Protoc. 2019 Oct 2;8(10):e13696. doi: 10.2196/13696. PMID: 31579027
2. Carter R, Cheraghchi-Bashi A, Westhorpe A, Yu S, Shanneik Y, Seraia E, Ouaret D, Inoue Y, Koch C, Wilding J, Ebner D, Ryan AJ, Buffa FM, Sharma RA. Identification of anticancer drugs to radiosensitise <i>BRAF</i>-wild-type and mutant colorectal cancer. Cancer Biol Med. 2019 May;16(2):234-246. doi: 10.20892/j.issn.2095-3941.2018.0284. PMID: 31516745
3. Winter H, Rassam J, Virdee PS, Goldin R, Pitcheshwar P, Weaver K, Primrose J, Berry DP, Wasan HS, Sharma RA. Hepatic Resection Following Selective Internal Radiation Therapy for Colorectal Cancer Metastases in the FOXFIRE Clinical Trial: Clinical Outcomes and Distribution of Microspheres. Cancers (Basel). 2019 Aug 12;11(8). pii: E1155. doi: 10.3390/cancers11081155. PMID: 31408970
4. White J, Carolan-Rees G, Dale M, Patrick HE, See TC, Bell JK, Manas DM, Crellin A, Slevin NJ, Sharma RA. Yttrium-90 Transarterial Radioembolization for Chemotherapy-Refractory Intrahepatic Cholangiocarcinoma: A Prospective, Observational Study. J Vasc Interv Radiol. 2019 Aug;30(8):1185-1192. doi: 10.1016/j.jvir.2019.03.018. Epub 2019 Jun 27. PMID: 31255499
5. Kosmin M, Ledsam J, Romera-Paredes B, Mendes R, Moinuddin S, de Souza D, Gunn L, Kelly C, Hughes CO, Karthikesalingam A, Nutting C, Sharma RA. Rapid advances in auto-segmentation of organs at risk and target volumes in head and neck cancer. Radiother Oncol. 2019 Jun;135:130-140. doi: 10.1016/j.radonc.2019.03.004. Epub 2019 Mar 22. Review. PMID: 31015159
6. Beaton L, Bandula S, Gaze MN, Sharma RA. How rapid advances in imaging are defining the future of precision radiation oncology. Br J Cancer. 2019 Apr;120(8):779-790. doi: 10.1038/s41416-019-0412-y. Epub 2019 Mar 26. Review. PMID: 30911090
7. Chauhan N, Mulcahy MF, Salem R, Benson Iii AB, Boucher E, Bukovcan J, Cosgrove D, Laframboise C, Lewandowski RJ, Master F, El-Rayes B, Strosberg JR, Sze DY, Sharma RA. TheraSphere Yttrium-90 Glass Microspheres Combined With Chemotherapy Versus Chemotherapy Alone in Second-Line Treatment of Patients With Metastatic Colorectal Carcinoma of the Liver: Protocol for the EPOCH Phase 3 Randomized Clinical Trial. JMIR Res Protoc. 2019 Jan 17;8(1):e11545. doi: 10.2196/11545. PMID: 30664496
8. Ahmad SS, Crittenden MR, Tran PT, Kluetz PG, Blumenthal GM, Bulbeck H, Baird RD, Williams KJ, Illidge T, Hahn SM, Lawrence TS, Spears PA, Walker AJ, Sharma RA. Clinical Development of Novel Drug-Radiotherapy Combinations. Clin Cancer Res. 2018 Nov 29. doi: 10.1158/1078-0432.CCR-18-2466. DOI: 10.1158/1078-0432.CCR-18-2466
9. White J, Carolan-Rees G, Dale M, Morgan HE, Patrick HE, See TC, Beeton EL, Swinson DEB, Bell JK, Manas DM, Crellin A, Slevin NJ, Sharma RA. Analysis of a National Programme for Selective Internal Radiation Therapy for Colorectal Cancer Liver Metastases. Clin Oncol (R Coll Radiol). 2018 Oct 5. pii: S0936-6555(18)30438-2. doi: 10.1016/j.clon.2018.09.002.
10. Falls KC, Sharma RA, Lawrence YR, Amos RA, Advani SJ, Ahmed MM, Vikram B, Coleman CN, Prasanna PG. Radiation-Drug Combinations to Improve Clinical Outcomes and Reduce Normal Tissue Toxicities: Current Challenges and New Approaches: Report of the Symposium Held at the 63rd Annual Meeting of the Radiation Research Society, 15-18 October 2017; Cancun, Mexico. Radiat Res. 2018 Oct;190(4):350-360. Doi: 10.1667/RR15121.1
11. Lyon PC, Winter H, Herbschleb K, Campo L, Carlisle R, Wu F, Goldin R, Coussios CC, Middleton MR, Gleeson FV, Boardman P, Sharma RA. Long-term radiological and histological outcomes following selective internal radiation therapy to liver metastases from breast cancer. Radiol Case Rep. 2018 Sep 22;13(6):1259-1266. doi: 10.1016/j.radcr.2018.08.020. eCollection 2018 Dec.
12. Ricketts K, Ahmad R, Beaton L, Cousins B, Critchley K, Davies M, Evans S, Fenuyi I, Gavriilidis A, Harmer QJ, Jayne D, Jefford M, Loizidou M, Macrobert A, Moorcroft S, Naasani I, Ong ZY, Prise KM, Rannard S, Richards T, Schettino G, Sharma RA, Tillement O, Wakefield G, Williams NR, Yaghini E, Royle G.  Recommendations for clinical translation of nanoparticle-enhanced radiotherapy. Br J Radiol. 2018 Sep 17:20180325. doi: 10.1259/bjr.20180325.
13. Gill S, Liu DM, Green HM and Sharma RA. Beyond the Knife: The Evolving Management of Oligometastatic Colorectal Cancer. Am Soc Clin Oncol Educ Book. 2018 May 23;(38):209-219. doi: 10.1200/EDBK_200941.
14. Kannan P, Kretzschmar WW, Winter H, Warren DR, Bates R, Allen PD, Syed N, Irving B, Papież BW, Kaeppler J, Markelc B, Kinchesh P, Gilchrist S, Smart SC, Schnabel JA, Maughan TS, Harris AL, Muschel RJ, Partridge M, Sharma RA, Kersemans V. Functional parameters derived from magnetic resonance imaging reflect vascular morphology in preclinical tumors and in human liver metastases. Clin Cancer Res. 2018 Jun 29. pii: clincanres.0033.2018. doi: 10.1158/1078-0432
15. MacGregor TP, Carter R, Gillies RS, Findlay JM, Kartsonaki C, Castro-Giner F, Sahgal N, Wang LM, Chetty R, Maynard ND, Cazier JB, Buffa F, McHugh PJ, Tomlinson I, Middleton MR, Sharma RA. Translational study identifies XPF and MUS81 as predictive biomarkers for oxaliplatin-based peri-operative chemotherapy in patients with esophageal adenocarcinoma. Sci Rep. 2018 May 8;8(1):7265. doi: 10.1038/s41598-018-24232-2.
16. Sharma RA, Fumi L, Audisio RA, Denys A, Wood BJ, Pignatti F. Assessment of medical devices: the Emperor's new clothes: Author reply. Br J Radiol. 2018 May 11:20180310. doi: 10.1259/bjr.20180310.
17. National Cancer Research Institute Clinical and Translational Radiotherapy Research working Group (CTRad) Proton Beam Clinic Trial Strategy Group. Proton Beam Therapy – the Challenges of Delivering High –quality Evidence of Clinical Benefit. Clin Oncol (R Coll Radiol). 2018 May; 30(5):290-284. Doi: 10.1016/j.clon.2018.02.031
18. Ralli G, Chappell M, McGowan D, Sharma R, Higgins G and Fenwick J. 4D-PET Reconstruction using a Spline-Residue Model with Spatial and Temporal Roughness Penalities. Phys Med Biol. 2018 Apr 4.
19.  Labib PL, Davidson BR, Pereira SP, Sharma RA. Locoregional therapies in cholangiocarcinoma. Hepatic Oncology. 2017 Nov; 4(4), 99-109
20. Kennedy A, Brown DB, Feilchenfeldt J, Marshall J, Wasan H, Fakih M, Gibbs P, Knuth A, Sangro B, Soulen MC, Pittari G, Sharma RA. Safety of selective internal radiation therapy (SIRT) with yttrium-90 microspheres combined with systemic anticancer agents: expert consensus. J Gastrointest Oncol. 2017 Dec;8(6):1079-1099. doi: 10.21037/jgo.2017.09.10.
21. Sharma RA, Gibbs P, Sharma NK, Ricke J, Taieb J, Moschandreas J, Virdee PS, Dutton P, van Hazel G, Wasan HS., Adequate SIRT activity dose is as important as adequate chemotherapy dose - Authors' reply. Lancet Oncol. 2017 Nov;18(11):e637. doi: 10.1016/S1470-2045(17)30801-X.
22. Sharma RA, Fumi L, Audisio RA, Denys A, Wood BJ, Pignatti F., How will interventional oncology navigate the "valleys of death" for new medical devices? Br J Radiol. 2017 Nov 27:20170643. doi: 10.1259/bjr.20170643.
23. Harrington, K., Hall, E., Hawkins, M., Henry, A., MacKay, R., Maughan, T., McDonald, A., Nutting, C., Oelfke, U., Sebag-Montefiore, D., Sharma, R.A., van Herk, M., Faivre-Finn, C., Introducing the Cancer Research UK Advanced Radiotherapy Technologies Network (ART-NET). Clinical Oncology, Available online 12 August 2017, ISSN 0936-6555. doi.org/10.1016/j.clon.2017.07.016
24. Rali GP, McGowan DR, Chappell MA, Sharma RA, Higgins GS and Fenwick JD, 4D-PET reconstruction of synamic non-small cell lung cancer [18-F]-FMISO-PET data using adaptive-knot cubic B-splines. Biomedical Imaging (ISBI), 2017 IEEE 14^thInternational Symposium, pp 1189-1192.
25. Winter H, Kaisaki P, Harvey J, Carter R, Sharma R A, Tayor J C, McCullagh J, Circulating tumour DNA and oncometabolites in patients with intrahepatic cholangiocarcinoma. Annals of Oncology, 2017, DOI: 10.1093/annonc/mdx508.024.
26. Sangro B, Martinez-Urbistondo D, Bester L, Bilbao J I, Coldwell D M, Flamen P, Kennedy A, Ricke J, Sharma R A, Prevention and treatment of complications of selective internal radiation therapy: Expert guidance and systematic review. Hepatology, 2017, DOI: 10.1002/hep.29207.
27. Wasan, H.S., Gibbs, P., Sharma, N.K., Taieb, J., Heinemann, V., Ricke, J., Peeters, M., Findlay, M., Weaver, A., Mills, J., Wilson, C., Adams, R., Francis, A., Moschandreas, J., Virdee, P.S., Dutton. P., Love, S., Gebski, V., Gray, A., FOXFIRE trial investigators, SIRFLOX trial investigators, FOXFIRE-Global trial investigators, van Hazel, G., Sharma, R.A., First-line selective internal radiotherapy plus chemotherapy versus chemotherapy alone in patients with liver metastases from colorectal cancer (FOXFIRE, SIRFLOX, and FOXFIRE-Global): a combined analysis of three multicentre, randomised, phase 3 trials. Lancet Oncol. 2017 Aug 3. pii: S1470-2045(17)30457-6. doi: 10.1016/S1470-2045(17)30457-6
28. Wasan HS, van Hazel G, Heinemann G, Sharma RA et al., Overall survival analysis of the FOXFIRE-SIRFLOX-FOXFIRE global prospective randomized studies of first-line selective internal radiotherapy (SIRT) in patients with liver metastases from colorectal cancer. Annals of Oncology, 2017, Volume 28: 3, DOI: 10.1200/JCO.2017.35.15_suppl.3507.

 

24. Virdee, P.S, Moschandreas, J., Gebski, V., Love, S.B., Francis, E.A., Wasan, H.S., van Hazel, G., Gibbs, P., Sharma, R.A., Protocol for Combined Analysis of FOXFIRE, SIRFLOX, and FOXFIRE-Global Randomized Phase III Trials of Chemotherapy +/- Selective Internal Radiation Therapy as First-Line Treatment for Patients With Metastatic Colorectal Cancer. JMIR Res Protoc. 2017 Mar 28;6(3):e43. doi: 10.2196/resprot.7201.
25. O'Connor J.P., Aboagye E.O., Adams J.E., Aerts H.J., Barrington S.F., Beer A.J., Boellaard R., Bohndiek S.E., Brady M., Brown G., Buckley D.L., Chenevert T.L., Clarke L.P., Collette S., Cook G.J., deSouza N.M., Dickson J.C., Dive C., Evelhoch J.L., Faivre-Finn C., Gallagher F.A., Gilbert F.J., Gillies R.J., Goh V., Griffiths J.R., Groves A.M., Halligan S., Harris A.L., Hawkes D.J., Hoekstra O.S., Huang E.P., Hutton B.F., Jackson E.F., Jayson G.C., Jones A., Koh D.M., Lacombe D., Lambin P., Lassau N., Leach M.O., Lee T.Y., Leen E.L., Lewis J.S., Liu Y., Lythgoe M.F., Manoharan P., Maxwell R.J., Miles K.A., Morgan B., Morris S., Ng T., Padhani A.R., Parker G.J., Partridge M., Pathak A.P., Peet A.C., Punwani S., Reynolds A.R., Robinson S.P., Shankar L.K., Sharma R.A., Soloviev D., Stroobants S., Sullivan D.C., Taylor S.A., Tofts P.S., Tozer G.M., van Herk M., Walker-Samuel S., Wason J., Williams K.J., Workman P., Yankeelov T.E., Brindle K.M., McShane L.M., Jackson A., Waterton J.C. Imaging biomarker roadmap for cancer studies. Nat Rev Clin Oncol. 2016 Oct 11. doi: 10.1038/nrclinonc.2016.162. [Epub ahead of print].
26. Tree AC, Harding V, Bhangu A, Krishnasamy V, Morton D, Stebbing J, Wood BJ, Sharma RA.  The need for multidisciplinarity in specialist training to optimize future patient care. Nature Reviews Clinical Oncology, 2017, 14(8):508-517. doi: 10.1038/nrclinonc.2016.185.
27. Mukherjee, S., Hurt, C.N., Gwynne, S., Sebag-Montefiore, D., Radhakrishna, G., Gollins, S., Hawkins, M., Grabsch, H.I., Jones, G., Falk, S., Sharma, R., Bateman, A., rajarhi, R., Ray, R., Canham, J., Griffiths, G., Maughan, T., Crosby, T., NEOSCOPE: A randomised phase II study of induction chemotherapy followed by oxaliplatin/capecitabine or carboplatin/paclitaxel based pre-operative chemoradiation for resectable oesophageal adenocarcinoma. European Journal of Cancer, 2017 Mar; 74: 38-46. Doi: 10.1016/j.ejca.2016.11.031
28. Greenhaigh TA, Dearman C, Sharma RA, Combination of Novel Agents with Radiotherapy to treat rectal cancer. Clinical Oncology, 2016, 28(2):116-139. Doi: 10.1016/j.clon.2015.11.002.
29. Hill, E.J., Roberts, C., Franklin, J.M., Enescu, M., West, N., MacGregor, T.P., Chu, K.U.,  Boyle, L., Blesing, C., Wang, L.M., Mukherjee, S., Anderson, E.M., Brown, G., Dutton, S., Love, S.B., Schnabel, J.A., Quirke, P., Muschel, R., McKenna, W.G., Partridge, M., Sharma, R.A., Clinical Trial of Oral Nelfinavir before and during Radiation Therapy for Advanced Rectal Cancer. Clin Cancer Res, 2016 Feb 9. pii: clincanres.1489.2015. 2016 Apr 15;22(8):1922-31. doi: 10.1158/1078-0432.CCR-15-1489. Epub 2016 Feb 9.
30. Irving, B., Franklin, J.M., Papiez, B.W., Anderson, E.M., Sharma, R.A., Gleeson, F.V., Brady, S.M., Schnabel J.A. Pieces-of-parts for supervoxel segmentation with global context: Application to DCE-MRI tumor delineation. Med Image Anal. 2016 Aug; 32:69-83. doi: 10.1016/j.media.2016.03.002. Epub 2016 Mar 21
31. Irving B, Franklin JM., Papiez BW, Anderson EM, Sharma RA, Gleeson FV, Brady SM, Schnabel JA. Pieces-of-parts for supervoxel segmentation with global context: Application to DCE-MRI tumor delineation. Medical Image Analysis, 2016, 32:69-83. doi: 10.1016/j.media.2016.03.002.
32. Dearman, C., Van As, N., Crellin, A., Slevin, N., Sharma, R.A. Surgery versus SABR for resectable non-small-cell lung cancer. Lancet Oncol. 2015 Aug;16(8):e373-4. doi: 10.1016/S1470-2045(15)00145-X
33. Franklin JM, Sharma RA, Harris AL, Gleeson FV. Imaging oligometastatic cancer before local treatment. Lancet Oncol. 2016 Sep;17(9):e406-14. doi: 10.1016/S1470-2045(16)30277-7. Review..
34. Shiao, J., Winter, H., Sharma, R.A., Landmark study raises the bar for interventional oncology. Future Oncol. 2016 Aug;12(15):1747-9. doi: 10.2217/fon-2016-0212. Epub 2016 Jun 23. No abstract available.
35. Sharma, R.A., Plummer, R., Stock, J.K., et al., NCRI CTRad Academia-Pharma Joint Working Group. (2016). Clinical Development of New Drug-Radiotherapy Combinations. Nature Rev Clin Oncol, 2016 Jun 1. doi: 10.1038/nrclinonc.2016.79.
36. Findlay, J., Castro-Giner, F., Makino, S., Rayner, E., Kartsonaki, C., Cross, W., Kovac, M., Ulahannan, D., Palles, C., Gillies, R.G., McGregor, T.P., Church, D., Maynard, N.D., Buffa, F., Cazier, J.B., Graham, T.A., Wang, L.M., Sharma, R.A., Middleton, M.R., Tomlinson, I.  Differential clonal evolution in oesophageal cancers in response to neo-adjuvant chemotherapy.  Nat Commun, 2016 Apr 5;7: 11111. doi: 10.1038/ncomms11111.
37. Carter, R., Westhorpe, A., Romero, M.J., Habtemariam, A., Gallevo, C.R., Bark, Y., Menezes, N., Sadler, P.J., Sharma, R.A.  Radiosensitisation of human colorectal cancer cells by ruthenium(II) arene anticancer complexes.  Sci Rep, 2016, 6: 20596. doi: 10.1038/srep20596.
38. Dearman C, Hill EJ, Franklin J, Wang LM, Silva M, Sadler, Sharma RA,  Management of thyroid “incidentalomas” in patients with cancer.  International Medical Case Reports, 2015, 8:247-9, doi: 10.2147/IMCRJ.S92857
39. Mukherjee S, Hurt CN, Gwynne S, Bateman A, Gollins S, Radhakrishna G, Hawkins M, Canham J, Lewis W, Grabsch HI, Sharma RA, Wade W, Maggs R, Tranter B, Roberts A, Sebag-Montefiore D, Maughan T, Griffiths G, Crosby T.  NEOSCOPE: a randomised Phase II study of induction chemotherapy followed by either oxaliplatin/capecitabine or paclitaxel/carboplatin based chemoradiation as pre-operative regimen for resectable oesophageal adenocarcinoma. BMC Cancer, 2015, 15:48, doi: 10.1186/s12885-015-1062-y.
40. Kennedy A, Bester L, Salem R, Sharma RA, Parks RW, Ruszniewski P.  Role of hepatic intra-arterial therapies in metastatic neuroendocrine tumours (NET): guidelines from the NET-Liver-Metastases Consensus Conference.  HPB, 2015, 17(1): 29-37. doi: 10.1111/hpb.12326.
41. Franklin, J.M., Gebski, V., Poston, G.J., Sharma, R.A. Clinical trials of interventional oncology-moving from efficacy to outcomes. Nat Rev Clin Oncol. 2015 Feb;12(2):93-104. doi: 10.1038/nrclinonc.2014.199. Epub 2014 Dec 9.
42. Crosby T, Mukherkee S, Sharma RA, et al. NeoSCOPE: A phase II randomized comparison of neoadjuvant oxaliplatin/capecitabine versus carboplatin/paclitaxel-based chemoradiation in operable esophageal cancer. Journal of Clinical Oncology, 2014, Volume 31, Issue 15. Doi:10.1200/jco.2014.32.15_suppl.tps4144.