Publications

Marza, E., Simonsen, K.T., Færgeman, N.J. and Lesa, G.M. (2009). Expression of ceramide glucosyltransferases, which are essential for glycosphingolipid synthesis, is only required in a small subset of C. elegens cells. J. Cell Sci., 122, 822-833.
Marza, E., Long, T., Saiardi, A., Sumakovic, M., Eimer, S. Hall, D.H., and Lesa, G.M. (2008). Polyunsaturated fatty acids influence synaptojanin localization to regulate synaptic vesicle recycling. Mol. Biol. Cell, 19, 833-842.

Lesa, G.M. (2006). Isolation of C. elegans gene knockouts by PCR screening of chemically mutagenized libraries. Nat. Protoc., 1, 2231-2240.

Marza, E. and Lesa, G.M. (2006) Polyunsaturated fatty acids and neurotransmission in C. elegans, Biochem. Soc. Trans., 34, 77-80.
Lesa, G.M., Palfreyman, M., Hall, D.H., Clandinin, M.T., Rudolph, C., Jorgensen, E.M. and Schiavo, G. (2003). Polyunsaturated fatty acids are required for efficient neurotransmission in C. elegans, J. Cell Sci., 116, 4965-4975.
Yoon, C., Chang, C., Hopper N., Lesa, G.M., and Sternberg P.W. (2000). Requirements of multiple domains of SLI-1, a C. elegans homolog of c-Cbl, and an inhibitory tyrosine in LET-23 in regulating vulval differentiation, Mol. Biol. Cell, 11, 4019–4031.
Lesa, G.M., Seemann, J., Shorter, J., Vandekerckhove, J., and Warren G.B. (2000). The amino-terminal domain of the Golgi protein Giantin interacts directly with the vesicle-tethering protein p115, J. Biol. Chem., 275, 2831–2836.
Lesa, G.M. and Sternberg, P.W. (1997). Positive and negative tissue-specific signaling by a nematode EGF receptor, Mol. Biol. Cell, 8, 779-793.
Katz, W.S., Lesa, G.M., Yannoukakos, D., Clandinin, T.R., Schlessinger, J., and Sternberg, P.W. (1996). A point mutation in the extracellular domain activates LET-23, the C. elegans EGF receptor homolog, Mol. Cell. Biol., 16, 529-537.
Sternberg, P.W., Lesa, G., Lee, J., Katz, W.S., Yoon, C., Clandinin, T.R., Huang, L.S., Chamberlin, H.M., and Jongeward, G. (1995). LET-23-mediated signal transduction during Caenorhabditis elegans development. Mol. Reprod. Dev., 42, 523-528.
Romualdi, P., Lesa, G., Donatini, A., Ferri, S. (1995). Long term exposure to opioid antagonists up-regulates prodynorphin gene expression in rat brain, Brain Res., 672, 42-47.
Aroian, R.V., Lesa, G.M., and Sternberg, P.W. (1994). Mutations in the Caenorhabditis elegans let-23 EGF Receptor-like gene define elements important for tissue specificity and function, EMBO J., 13, 360-366.
Romualdi, P., Lesa, G., Donatini, A., Balboni, G., Tomatis, R., Ferri, S. (1992). Alterations in Vasoactive Intestinal Polypeptide-related peptides after pentylenetetrazole-induced seizures in rat brain, Eur. J. Pharmacol., 229, 149-153.
Pincelli, C., Fantini, F., Romualdi, P., Sevignani, C., Lesa, G., Benassi, L., Giannetti, A. (1992). Substance P is diminished and VIP is augmented in psoriatic lesions and these peptides exert disparate effects on the proliferation of cultured human keratinocytes, J. Invest. Dermatol., 98, 421-427.
Romualdi, P., Lesa, G, and Ferri, S. (1991).  Chronic opiate agonists down regulate prodynorphin gene expression in rat brain, Brain Res., 563, 132-136.
Romualdi, P., Lesa, G, Cox, B.M., and Ferri, S. (1990). Distribution and characterization of VIP-related peptides in the rat spinal cord, Neuropeptides, 16, 219-225.
Spada, G.P., Lesa, G, Gottarelli, G., De Maria, P., and Mariani, P. (1988). A study of the enolization of some alkyl ketones in lyomesophases formed by alkylammonium surfactants, Liq. Crystals, 3, 1031-1037.