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Professor Pascale Guillot - 'Stem Cell Therapy: My Story' Professor Ertan Saridogan - 'The Truth is Rarely Pure and Never Simple'
Professor Pascale Guillot - Stem Cell Therapy: My Story
Pascale V Guillot is a Professor of Stem Cell and Gene Therapy who specialises in developing cutting edge treatments for babies and children. Her research group develops human induced pluripotent stem cell based platforms to investigate the repair potential of fetal mesenchymal stem cells and the extracellular vesicles they release. They are now developing cell-free therapeutics to understand the regulation of gene activity by exosomal microRNAs.
Pascale’ s interest in research started very early. As a young teenager in Paris, she started working in an animal facility and breeding mice to create and maintain inbred strains of mice, working on the Y chromosome and behaviour genetics. At school, she obtained a BSc in Mathematics and Physics, followed the same year by two masters, one in neuroscience and one in psychophysiology. Whilst working in the genetics lab, she started publishing her first papers in mouse genetics and went on doing her PhD in genetics with the philosopher George Chapouthier, well known for his work on the relation between animals and humans.
She then moved to Oxford at the Harwell Centre, under the supervision of Mary Lyon, and Bruce Cattanach, both pioneers in genetics who made a remarkable number of fundamental discoveries including X-inactivation and genomic imprinting. Pascale then went to the US with Mary Lyon to work at the Jackson laboratory, and Mary remained her very close mentor and friend until her death. Pascale then went to Harvard Medical school and the MIT in Boston, to work on gene targeting and developing bench transgenics before moving to the NIH in Washington DC to work on gene editing. She then moved back to England, working first at Imperial College on gene transcription and next on brittle bone disease, before joining UCL and the EGA Institute for Women’s Health in 2013.
More about Professor Pascale Guillot
Professor Pascale Guillot - Inaugural Lecture Slides
Professor Ertan Saridogan - 'The truth is rarely pure and never simple'
