MEDC0085 The genetics and epigenetics of diseases
|The genetics and epigenetics of diseases|
|Module Leader||Dr Ariane Chapgier|
Precision medicine has three essential attributes:
1) A mechanistic understanding of the aetiology and pathogenesis of disease.
2) The ability to detect (diagnose in the clinical laboratory) specific causal factors.
3) The ability to specifically treat the underlying cause(s)
The module will cover these three attributes.
Genetic and epigenetic diseases covering the different modes of inheritance and de novo mutations with their molecular mechanisms. Mendelian autosomal recessive, autosomal dominant, X-linked, mitochondrial, polygenic and epigenetics. Examples in infectious diseases and cancer. Link to diabetes will be covered in later modules.
|Module assessment||50% course work + 50% unseen 1 hour exam|