MEDC0075 Module 1:Bioinformatics and structural biology as applied to drug design

Module 1: Bioinformatics and structural biology as applied to drug design MEDC0075 Dr Edith Chan Module Structure: (15 credits each) • Lectures and Tutorials • Assessment: 50% coursework, 50% unseen examination.

Module Title	Module 1: Bioinformatics and structural biology as applied to drug design
Module Code	MEDC0075
Module Leader	Dr Edith Chan
Short description	In the post genomic era, use of Bioinformatics is important in many aspects of drug discovery, such as gene sequencing or target discovery. Biochemistry holds the key position in drug discovery at the interface of chemistry and biology. The fundamental of these two important areas in drug discovery process is taught. It is essential for students to understand the basic principles.
Module aims	Basic principles of Bioinfomatics and use of online databases Basic principles of biochemistry and structural biology of proteins Basic principles of modern protein structural determination techniques To teach students to use simple Bioinformatics, such as Blast and RasMol To teach students to use cloning software BioEdit To teach students to use RasMol and PyMol
List of Lectures and Tutorials	Introduction to Bioinformatics Bioinformatics of drug targets Use of Bioinformatics databases Cloning and expression of proteins for structural studies Structural Biology and tools Blast and sequence alignment Protein structure family
Module assessment	50% course work + 50% unseen 1 hour exam