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Translational Research Office (TRO)

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The articles in this blog will focus on the main barriers to translational research and how to overcome these.

Early Career Innovators: Improving Nerve Regeneration with Chemokine Receptor Inhibitors, Repurposing TIN

In this Repurposing TIN interview as part of the Early Career Innovators series, recognising the amazing translational work being done by postdoc and non-tenured researchers within the UCL Therapeutic Innovation Networks (TINs), Dr Guillem Mòdol Caballero highlights his Repurposing TIN Pilot Data Fund awarded project, involving the use of chemokines as a novel target to improve peripheral nerve regeneration.

Early Career Innovators: Repurposing mutant gene reactivators for Pancreatic Cancer, Repurposing TIN

In this Repurposing TIN interview as part of the Early Career Innovators series, acknowledging the amazing translational work being done by postdoc and non-tenured researchers within the UCL Therapeutic Innovation Networks (TINs), Dr Pilar Acedo highlights her Repurposing TIN Pilot Data Fund awarded project, involving the repurposing of gene P53 reactivators to treat pancreatic cancer.

Early Career Innovators: Repurposing Ibuprofen-similar drugs for Nerve Regeneration, Repurposing TIN

In this Repurposing TIN interview as part of the Early Career Innovators series, acknowledging the amazing translational work being done by early career and non-tenured researchers within the UCL Therapeutic Innovation Networks (TINs), Dr Melissa Rayner highlights her Repurposing TIN Pilot Data Fund awarded project, establishing a relationship between a drug’s affinity for PPARγ and nerve regeneration.

Early Career Innovators: Repurposing a Common Chemotherapy Drug for Bladder Cancer, Repurposing TIN

In this Repurposing TIN interview as part of the Early Career Innovators series, acknowledging the amazing translational work being done by early career and non-tenured researchers within the UCL Therapeutic Innovation Networks (TINs), Dr Jennifer Rohn highlights her Repurposing TIN Pilot Data Fund awarded project, involving the reformulation of the common chemo drug mitomycin-C for bladder cancer.

Early Career Innovators: Genetic Diagnosis of Inherited Retinal Disease with AI, Devices & Diagnostics TIN

In this Devices & Diagnostics TIN interview as part of the Early Career Innovators series, acknowledging the amazing translational work being done by early career researchers within the UCL Therapeutic Innovation Networks (TINs), Dr Nikolas Pontikos highlights his Devices & Diagnostics TIN (co-lead by the UCL Institute of Healthcare Engineering’s Translational & Industry Delivery Group) Pilot Data Fund awarded project, involving the use of artificial intelligence to accelerate genetic diagnosis of inherited retinal disease.

Early Career Innovators: Understanding the Role of Brain Oxygenation in Multiple Sclerosis, Devices & Diagnostics TIN

In this next Devices & Diagnostics TIN interview as part of the Early Career Innovators series, acknowledging the amazing translational work being done by early career researchers within the UCL Therapeutic Innovation Networks (TINs), Dr Frédéric Lange highlights his Devices & Diagnostics TIN (co-lead by the UCL Institute of Healthcare Engineering’s Translational & Industry Delivery Group) Pilot Data Fund awarded project, “Understanding the role of brain oxygenation and metabolism in the pathophysiology and prognosis of relapses and progression in multiple s

Early Career Innovators: Personalised Therapy for Prostate Cancer from Diagnosis, Devices & Diagnostics TIN

In the first Devices & Diagnostics TIN interview as part of the Early Career Innovators series, acknowledging the amazing translational work being done by early career researchers within the UCL Therapeutic Innovation Networks (TINs), Dr Hayley Pye highlights her Devices & Diagnostics TIN (co-lead by the UCL Institute of Healthcare Engineering’s Translational & Industry Delivery Group) Pilot Data Fund awarded project, “Personalising pathology for prostate cancer, a unique opportunity at UCL/UCLH”.

Gene Therapy explained: Changing our bodies’ recipe to treat disease

Written by Linda von Nerée, NIHR Blood and Transplant Research Unit in Stem Cells and Immunotherapies at UCL.

How many pairs of jeans do you have in your wardrobe? How many genes are in your body? What are genes anyway and do you know how they can help to treat an illness?!

All is explained in this brand-new animation from us at the NIHR Blood and Transplant Research Unit in Stem Cells and Immunotherapies at University College London (UCL BTRU). Well, except how many jeans you own, that stays your secret.

Early Career Innovators: Enhancing Stathmin-2 protein in Neurodegenerative Diseases, Small Molecules TIN

In the next Small Molecules TIN interview as part of the Early Career Innovators series, acknowledging the amazing translational work being done by early career researchers within the UCL Therapeutic Innovation Networks (TINs), Benedikt Hölbling highlights his Small Molecules TIN Pilot Data Fund awarded project, “Enhancing Stathmin-2 protein levels in familial and sporadic ALS/FTD”.

Early Career Innovators: Therapeutic Vulnerabilities of an Oncoprotein in Tumour Initiation, Small Molecules TIN

In the next Small Molecules TIN interview as part of the Early Career Innovators series, acknowledging the amazing translational work being done by early career researchers within the UCL Therapeutic Innovation Networks (TINs), Dr Victor Llombart highlights his Small Molecules TIN Pilot Data Fund awarded project, “Identifying therapeutic vulnerabilities of MYC through next generation structure-function”.

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