2019 Publications

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Acceptability of a first-line anti-tuberculosis formulation for children: qualitative data from the SHINE trial.  (2019) Wademan, D. T., L. Busakwe, T. J. Nicholson, M. van der Zalm, M. Palmer, J. Workman, A. Turkova, A. M. Crook, J. Thomason, D. M. Gibb, J. Seeley, A. Hesseling and G. Hoddinott  Int J Tuberc Lung Dis 23(12): 1263-1268 https://doi.org/10.5588/ijtld.19.0115.

Advanced immunodiagnostic tests for paediatric tuberculosis.  (2019) Villanueva, P., E. Sudbury, R. Song, M. Tebruegge and N. Curtis  Lancet Infect Dis 19(5): 467-468  https://doi.org/10.1016/S1473-3099(19)30175-6.

Advances in molecular diagnostic testing for central nervous system infections.  (2019) Houlihan, C. F., T. Bharucha and J. Breuer  Curr Opin Infect Dis 32(3): 244-250 https://doi.org/10.1097/QCO.0000000000000548.

After the UNGA High-Level Meeting on Tuberculosis-what next and how?  (2019) Sahu, S., L. Ditiu and A. Zumla  Lancet Glob Health 7(5): e558-e560 https://doi.org/10.1016/S2214-109X(19)30068-3.

App-based symptoms screening with Xpert MTB/RIF Ultra assay used for active tuberculosis detection in migrants at point of arrivals in Italy: The E-DETECT TB intervention analysis.  (2019) Barcellini, L., E. Borroni, C. Cimaglia, E. Girardi, A. Matteelli, V. Marchese, G. Stancanelli, I. Abubakar, E. D. T. B. C. members of the and D. M. Cirillo  PLoS One 14(7): e0218039 https://doi.org/10.1371/journal.pone.0218039.

Application of machine learning techniques to tuberculosis drug resistance analysis.  (2019) Kouchaki, S., Y. Yang, T. M. Walker, A. Sarah Walker, D. J. Wilson, T. E. A. Peto, D. W. Crook, C. R. Consortium and D. A. Clifton  Bioinformatics 35(13): 2276-2282 https://doi.org/10.1093/bioinformatics/bty949.

Assessment of the use and need for an integrated molecular surveillance of tuberculosis: an online survey in Germany.  (2019) Sanchini, A., M. Andres, L. Fiebig, S. Albrecht, B. Hauer and W. Haas  BMC Public Health 19(1): 321 https://doi.org/10.1186/s12889-019-6631-6.

Bacteriologically-confirmed pulmonary tuberculosis in an Ethiopian prison: Prevalence from screening of entrant and resident prisoners.  (2019) Tsegaye Sahle, E., J. Blumenthal, S. Jain, S. Sun, J. Young, T. Manyazewal, H. Woldeamanuel, L. Teferra, B. Feleke, O. Vandenberg, Z. Rey, M. Briggs-Hagen, R. Haubrich, W. Amogne and J. A. McCutchan  PLoS One 14(12): e0226160 https://doi.org/10.1371/journal.pone.0226160.

BCG vaccination following latent TB treatment: Possible implications for different settings.  (2019) Gosce, L., J. Bitencourt, R. K. Gupta, S. Arruda, L. C. Rodrigues and I. Abubakar  Int J Infect Dis 80S: S17-S19 https://doi.org/10.1016/j.ijid.2019.02.026.

Bedaquiline, moxifloxacin, pretomanid, and pyrazinamide during the first 8 weeks of treatment of patients with drug-susceptible or drug-resistant pulmonary tuberculosis: a multicentre, open-label, partially randomised, phase 2b trial.  (2019) Tweed, C. D., R. Dawson, D. A. Burger, A. Conradie, A. M. Crook, C. M. Mendel, F. Conradie, A. H. Diacon, N. E. Ntinginya, D. E. Everitt, F. Haraka, M. Li, C. H. van Niekerk, A. Okwera, M. S. Rassool, K. Reither, M. A. Sebe, S. Staples, E. Variava and M. Spigelman  Lancet Respir Med 7(12): 1048-1058 https://doi.org/10.1016/S2213-2600(19)30366-2.

Blood transcriptomic stratification of short-term risk in contacts of tuberculosis.  (2019) Roe, J., C. Venturini, R. K. Gupta, C. Gurry, B. M. Chain, Y. Sun, J. Southern, C. Jackson, M. C. Lipman, R. F. Miller, A. R. Martineau, I. Abubakar and M. Noursadeghi  Clin Infect Dis https://doi.org/10.1093/cid/ciz252.

British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults.  (2019) Lamb, C. A., N. A. Kennedy, T. Raine, P. A. Hendy, P. J. Smith, J. K. Limdi, B. Hayee, M. C. E. Lomer, G. C. Parkes, C. Selinger, K. J. Barrett, R. J. Davies, C. Bennett, S. Gittens, M. G. Dunlop, O. Faiz, A. Fraser, V. Garrick, P. D. Johnston, M. Parkes, J. Sanderson, H. Terry, I. B. D. g. e. c. group, D. R. Gaya, T. H. Iqbal, S. A. Taylor, M. Smith, M. Brookes, R. Hansen and A. B. Hawthorne  Gut 68(Suppl 3): s1-s106 https://doi.org/10.1136/gutjnl-2019-318484.

Building a European database to gather multi-country evidence on active and latent TB screening for migrants.  (2019) Ohd, J. N., K. Lonnroth, I. Abubakar, R. W. Aldridge, C. Erkens, J. Jonsson, V. Marchese, A. Matteelli, D. Menezes, D. Zenner and M. P. Hergens  Int J Infect Dis 80S: S45-S49 https://doi.org/10.1016/j.ijid.2019.02.041.

The burden of latent multidrug-resistant tuberculosis.  (2019) Garcia-Basteiro, A. L., H. E. Jenkins and M. Rangaka  Lancet Infect Dis 19(8): 802-803 https://doi.org/10.1016/S1473-3099(19)30271-3.

Burden of multidrug-resistant tuberculosis in England: a focus on prevalent cases.  (2019) Lalor, M. K., S. Perkins and H. L. Thomas  Int J Tuberc Lung Dis 23(6): 707-713 https://doi.org/10.5588/ijtld.18.0399.

Calcineurin Inhibitors and Variation in the Performance of Interferon-gamma Release Assays Used to Detect Tuberculosis Infection.  (2019) Barton, E., Y. Gao, D. Ball, K. Fidler, N. Klein, N. Curtis, V. Clifford, B. G. Marshall, A. Chancellor, S. Mansour, P. Elkington and M. Tebruegge  Ann Am Thorac Soc 16(6): 771-775 https://doi.org/10.1513/AnnalsATS.201811-784RL.

Can phenotypic data complement our understanding of antimycobacterial effects for drug combinations?  (2019) Kloprogge, F., R. Hammond, A. Copas, S. H. Gillespie and O. Della Pasqua  J Antimicrob Chemother 74(12): 3530-3536 https://doi.org/10.1093/jac/dkz369.

Cell wall peptidoglycan in Mycobacterium tuberculosis: An Achilles' heel for the TB-causing pathogen.  (2019) Maitra, A., T. Munshi, J. Healy, L. T. Martin, W. Vollmer, N. H. Keep and S. Bhakta  FEMS Microbiol Rev 43(5): 548-575 https://doi.org/10.1093/femsre/fuz016.

The Changing Landscape of Childhood Tuberculosis in the United Kingdom: A Retrospective Cohort (2000-2015).  (2019) Mohiyuddin, T., J. A. Seddon, H. L. Thomas and M. K. Lalor  Pediatr Infect Dis J 38(5): 470-475 https://doi.org/10.1097/INF.0000000000002200.

The changing treatment landscape for MDR/XDR-TB - Can current clinical trials revolutionise and inform a brave new world?  (2019) Honeyborne, I., M. Lipman, A. Zumla and T. D. McHugh  Int J Infect Dis 80S: S23-S28 https://doi.org/10.1016/j.ijid.2019.02.006.

Children With Cystic Fibrosis Are Infected With Multiple Subpopulations of Mycobacterium abscessus With Different Antimicrobial Resistance Profiles.  (2019) Shaw, L. P., R. M. Doyle, E. Kavaliunaite, H. Spencer, F. Balloux, G. Dixon and K. A. Harris  Clin Infect Dis 69(10): 1678-1686 https://doi.org/10.1093/cid/ciz069.

Chronic mucocutaneous candidiasis due to gain-of-function mutation in STAT1.  (2019) Carey, B., J. Lambourne, S. Porter and T. Hodgson  Oral Dis 25(3): 684-692 https://doi.org/10.1111/odi.12881.

Clinical utility of existing and second-generation interferon-gamma release assays for diagnostic evaluation of tuberculosis: an observational cohort study.  (2019) Whitworth, H. S., A. Badhan, A. A. Boakye, Y. Takwoingi, M. Rees-Roberts, C. Partlett, H. Lambie, J. Innes, G. Cooke, M. Lipman, C. Conlon, D. Macallan, F. Chua, F. A. Post, M. Wiselka, G. Woltmann, J. J. Deeks, O. M. Kon, A. Lalvani and g. Interferon-gamma Release Assays for Diagnostic Evaluation of Active Tuberculosis study  Lancet Infect Dis 19(2): 193-202 https://doi.org/10.1016/S1473-3099(18)30613-3.

Community-based testing of migrants for infectious diseases (COMBAT-ID): impact, acceptability and cost-effectiveness of identifying infectious diseases among migrants in primary care: protocol for an interrupted time-series, qualitative and health economic analysis.  (2019) Pareek, M., H. C. Eborall, F. Wobi, K. S. Ellis, E. Kontopantelis, F. Zhang, R. Baggaley, T. D. Hollingsworth, D. Baines, H. Patel, P. Haldar, M. Patel, I. Stephenson, I. Browne, P. Gill, R. Kapur, A. Farooqi, I. Abubakar and C. Griffiths  BMJ Open 9(3): e029188 https://doi.org/10.1136/bmjopen-2019-029188.

Cost minimization analysis of line probe assay for detection of multidrug-resistant tuberculosis in Arkhangelsk region of Russian Federation.  (2019) Bogdanova, E. N., A. O. Mariandyshev, G. A. Balantcev, P. I. Eliseev, E. I. Nikishova, A. I. Gaida, D. Enarson, A. Detjen, R. Dacombe, P. P. J. Phillips, S. B. Squire and E. Gospodarevskaya  PLoS One 14(1): e0211203 https://doi.org/10.1371/journal.pone.0211203.

Cross-transmission is not the source of new Mycobacterium abscessus infections in a multi-centre cohort of cystic fibrosis patients.  (2019) Doyle, R. M., M. Rubio, G. Dixon, J. Hartley, N. Klein, P. Coll and K. A. Harris  Clin Infect Dis https://doi.org/10.1093/cid/ciz526.

Cytokine biomarkers for the diagnosis of tuberculosis infection and disease in adults in a low prevalence setting.  (2019) Clifford, V., M. Tebruegge, C. Zufferey, S. Germano, B. Forbes, L. Cosentino, E. Matchett, E. McBryde, D. Eisen, R. Robins-Browne, A. Street, J. Denholm and N. Curtis  Tuberculosis (Edinb) 114: 91-102 https://doi.org/10.1016/j.tube.2018.08.011.

Developing a pathway for the diagnosis and management of ocular tuberculosis. The pan-LOndon Ocular tuberculosis Pathway-LOOP.  (2019) Petrushkin, H., C. Sethi, J. Potter, L. Martin, G. Russell, V. White, S. Ajamil-Rodanes, M. Brown, R. Breen, M. Lipman, I. Cropley, R. McDermott, A. Roche, H. Booth, J. Milburn, M. Darmalingam, R. Lee, C. Pavesio, M. Stanford, O. M. Kon and G. Bothamley  Eye (Lond) https://doi.org/10.1038/s41433-019-0543-7.

Diabetes mellitus and latent tuberculosis infection: baseline analysis of a large UK cohort.  (2019) Jackson, C., J. Southern, A. Lalvani, F. Drobniewski, C. J. Griffiths, M. Lipman, G. H. Bothamley, J. J. Deeks, A. Imran, O. M. Kon, S. Mpofu, V. Nikolayevskyy, M. Rees-Roberts, A. Sitch, S. Sridhar, C. Y. Tsou, H. Whitworth and I. Abubakar  Thorax 74(1): 91-94 https://doi.org/10.1136/thoraxjnl-2017-211124.

Diagnostic Bacteriology in District Hospitals in Sub-Saharan Africa: At the Forefront of the Containment of Antimicrobial Resistance.  (2019) Jacobs, J., L. Hardy, M. Semret, O. Lunguya, T. Phe, D. Affolabi, C. Yansouni and O. Vandenberg  Front Med (Lausanne) 6: 205 https://doi.org/10.3389/fmed.2019.00205.

Differential Pathogen-Specific Immune Reconstitution in Antiretroviral Therapy-Treated Human Immunodeficiency Virus-Infected Children.  (2019) Muenchhoff, M., E. Adland, J. Roider, H. Kloverpris, A. Leslie, S. Boehm, O. T. Keppler, T. Ndung'u and P. J. R. Goulder  J Infect Dis 219(9): 1407-1417 https://doi.org/10.1093/infdis/jiy668.

Discordance in latent tuberculosis (TB) test results in patients with end-stage renal disease.  (2019) Southern, J., S. Sridhar, C. Y. Tsou, S. Hopkins, S. Collier, V. Nikolayevskyy, S. Lozewicz, A. Lalvani, I. Abubakar and M. Lipman  Public Health 166: 34-39 https://doi.org/10.1016/j.puhe.2018.09.023.

Does sexual behaviour of people with HIV reflect antiretroviral therapy as a preventive strategy? A cross-sectional study among outpatients in Kenya.  (2019) Nkhoma, K., A. Ahmed, Z. Alli, L. Sherr and R. Harding  BMC Public Health 19(1): 1254 https://doi.org/10.1186/s12889-019-7581-8.

Dual RNA-Seq of Human Leprosy Lesions Identifies Bacterial Determinants Linked to Host Immune Response.  (2019) Montoya, D. J., P. Andrade, B. J. A. Silva, R. M. B. Teles, F. Ma, B. Bryson, S. Sadanand, T. Noel, J. Lu, E. Sarno, K. B. Arnvig, D. Young, R. Lahiri, D. L. Williams, S. Fortune, B. R. Bloom, M. Pellegrini and R. L. Modlin  Cell Rep 26(13): 3574-3585 e3573 https://doi.org/10.1016/j.celrep.2019.02.109.

Effectiveness of interventions for reducing TB incidence in countries with low TB incidence: a systematic review of reviews.  (2019) Collin, S. M., F. Wurie, M. C. Muzyamba, G. de Vries, K. Lonnroth, G. B. Migliori, I. Abubakar, S. R. Anderson and D. Zenner  Eur Respir Rev 28(152) https://doi.org/10.1183/16000617.0107-2018.

Effectiveness of pre-entry active tuberculosis and post-entry latent tuberculosis screening in new entrants to the UK: a retrospective, population-based cohort study.  (2019) Berrocal-Almanza, L. C., R. Harris, M. K. Lalor, M. C. Muzyamba, J. Were, A. M. O'Connell, A. Mirza, O. M. Kon, A. Lalvani and D. Zenner  Lancet Infect Dis 19(11): 1191-1201 https://doi.org/10.1016/S1473-3099(19)30260-9.

Engineered bacteriophages for treatment of a patient with a disseminated drug-resistant Mycobacterium abscessus. (2019) Dedrick, R. M., C. A. Guerrero-Bustamante, R. A. Garlena, D. A. Russell, K. Ford, K. Harris, K. C. Gilmour, J. Soothill, D. Jacobs-Sera, R. T. Schooley, G. F. Hatfull and H. Spencer. Nat Med 25(5): 730-733 https://doi.org/10.1038/s41591-019-0437-z

Etiology and Risk Factors for Mortality in an Adult Community-acquired Pneumonia Cohort in Malawi.  (2019) Aston, S. J., A. Ho, H. Jary, J. Huwa, T. Mitchell, S. Ibitoye, S. Greenwood, E. Joekes, A. Daire, J. Mallewa, D. Everett, M. Nyirenda, B. Faragher, H. C. Mwandumba, R. S. Heyderman and S. B. Gordon  Am J Respir Crit Care Med 200(3): 359-369 https://doi.org/10.1164/rccm.201807-1333OC.

Evaluations of clinical tobacco cessation interventions in Arab populations: A systematic review.  (2019) Alzahrane, A., R. West, H. K. Ubhi, J. Brown, N. Abdulqader and O. Samarkandi  Addict Behav 88: 169-174 https://doi.org/10.1016/j.addbeh.2018.08.017.

Evidence for supercoughers in an analysis of six tuberculosis cohorts from China, Peru, The Gambia and Uganda.  (2019) Handel, A., L. Martinez, J. N. Sekandi, S. E. Bellan, L. Zhu, C. Chen, Q. Liu, S. Donkor, J. Sutherland, P. C. Hill, R. H. Gilman, L. Grandjean and C. C. Whalen  Int J Tuberc Lung Dis 23(12): 1286-1292 https://doi.org/10.5588/ijtld.18.0819.

Exploring the effects of BCG vaccination in patients diagnosed with tuberculosis: Observational study using the Enhanced Tuberculosis Surveillance system.  (2019) Abbott, S., H. Christensen, M. K. Lalor, D. Zenner, C. Campbell, M. E. Ramsay and E. Brooks-Pollock  Vaccine 37(35): 5067-5072 https://doi.org/10.1016/j.vaccine.2019.06.056.

Fluoroquinolones and isoniazid-resistant tuberculosis: implications for the 2018 WHO guidance.  (2019) Stagg, H. R., G. H. Bothamley, J. A. Davidson, H. Kunst, M. K. Lalor, M. C. Lipman, M. G. Loutet, S. Lozewicz, T. Mohiyuddin, A. Abbara, E. Alexander, H. Booth, D. D. Creer, R. J. Harris, O. M. Kon, M. R. Loebinger, T. D. McHugh, H. J. Milburn, P. Palchaudhuri, P. P. J. Phillips, E. Schmok, L. Taylor, I. Abubakar and I. N. H. R. T. B. s. g. London  Eur Respir J 54(4) https://doi.org/10.1183/13993003.00982-2019.

Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis.  (2019) Ardain, A., R. Domingo-Gonzalez, S. Das, S. W. Kazer, N. C. Howard, A. Singh, M. Ahmed, S. Nhamoyebonde, J. Rangel-Moreno, P. Ogongo, L. Lu, D. Ramsuran, M. de la Luz Garcia-Hernandez, K. U. T, M. Darby, E. Park, F. Karim, L. Melocchi, R. Madansein, K. J. Dullabh, M. Dunlap, N. Marin-Agudelo, T. Ebihara, T. Ndung'u, D. Kaushal, A. S. Pym, J. K. Kolls, A. Steyn, J. Zuniga, W. Horsnell, W. M. Yokoyama, A. K. Shalek, H. N. Kloverpris, M. Colonna, A. Leslie and S. A. Khader  Nature 570(7762): 528-532 https://doi.org/10.1038/s41586-019-1276-2.

High-income countries and latent tuberculosis infection screening for migrants - Authors' reply.  (2019) Petersen, E., J. Chakaya, F. M. Jawad, G. Ippolito and A. Zumla  Lancet Infect Dis 19(7): 691-692 https://doi.org/10.1016/S1473-3099(19)30283-X.

HIV, Tuberculosis, and Otogenic Intracranial Sepsis: A Devastating Disease With a Subtle Presentation.  (2019) Yakobi, A., J. Z. Porterfield, J. Toman, T. Spock, N. Kapil, J. de Meyer, A. Kejner, P. Rea, M. Gleeson, B. Enicker, E. Michaelides and Y. Saman  Otol Neurotol 40(7): e704-e712 https://doi.org/10.1097/MAO.0000000000002290.

Identification and characterization of a novel anti-inflammatory lipid isolated from Mycobacterium vaccae, a soil-derived bacterium with immunoregulatory and stress resilience properties.  (2019) Smith, D. G., R. Martinelli, G. S. Besra, P. A. Illarionov, I. Szatmari, P. Brazda, M. A. Allen, W. Xu, X. Wang, L. Nagy, R. D. Dowell, G. A. W. Rook, L. Rosa Brunet and C. A. Lowry  Psychopharmacology (Berl) 236(5): 1653-1670 https://doi.org/10.1007/s00213-019-05253-9.

IMPACT study on intervening with a manualised package to achieve treatment adherence in people with tuberculosis: protocol paper for a mixed-methods study, including a pilot randomised controlled trial.  (2019) Stagg, H. R., I. Abubakar, C. N. Campbell, A. Copas, M. Darvell, R. Horne, K. Kielmann, H. Kunst, M. Mandelbaum, E. Pickett, A. Story, N. Vidal, F. B. Wurie and M. Lipman  BMJ Open 9(12): e032760 https://doi.org/10.1136/bmjopen-2019-032760.

Improving access to contraception through integration of family planning services into a multidrug-resistant tuberculosis treatment programme.  (2019) Cornish, E. F., J. Hudson, R. Sayers and M. Loveday  BMJ Sex Reprod Health https://doi.org/10.1136/bmjsrh-2019-200400.

Improving treatment outcomes for MDR-TB - Novel host-directed therapies and personalised medicine of the future.  (2019) Rao, M., G. Ippolito, S. Mfinanga, F. Ntoumi, D. Yeboah-Manu, C. Vilaplana, A. Zumla and M. Maeurer  Int J Infect Dis 80S: S62-S67 https://doi.org/10.1016/j.ijid.2019.01.039.

Individualising therapy for drug-sensitive tuberculosis.  (2019) Esmail, H., M. C. Lipman, A. Nunn and T. M. Walker  Lancet Respir Med 7(10): 834-835 https://doi.org/10.1016/S2213-2600(19)30247-4.

Integrated Target-Based and Phenotypic Screening Approaches for the Identification of Anti-Tubercular Agents That Bind to the Mycobacterial Adenylating Enzyme MbtA.  (2019) Ferguson, L., G. Wells, S. Bhakta, J. Johnson, J. Guzman, T. Parish, R. A. Prentice and F. Brucoli  ChemMedChem 14(19): 1735-1741 https://doi.org/10.1002/cmdc.201900217.

Interferon-gamma release assays have suboptimal sensitivity in both latent and active tuberculosis.  (2019) Goetzinger, F., I. Burkhardt, P. Villanueva, V. Clifford, N. Curtis and M. Tebruegge  Int J Tuberc Lung Dis 23(6): 766-767 https://doi.org/10.5588/ijtld.18.0603.

Keeping phase III tuberculosis trials relevant: Adapting to a rapidly changing landscape.  (2019) Phillips, P. P. J., C. D. Mitnick, J. D. Neaton, P. Nahid, C. Lienhardt and A. J. Nunn  PLoS Med 16(3): e1002767 https://doi.org/10.1371/journal.pmed.1002767.

Kidney disease in Africans with HIV and tuberculosis.  (2019) Wearne, N., R. Hung, R. Bohmer, R. Spies, A. Omar, S. Ash, F. Ibrahim, R. F. Miller, J. W. Booth, S. B. Lucas and F. A. Post  AIDS 33(7): 1207-1213 https://doi.org/10.1097/QAD.0000000000002204.

Latent TB Infection (LTBI) - Mycobacterium tuberculosis pathogenesis and the dynamics of the granuloma battleground.  (2019) Rao, M., G. Ippolito, S. Mfinanga, F. Ntoumi, D. Yeboah-Manu, C. Vilaplana, A. Zumla and M. Maeurer  Int J Infect Dis 80S: S58-S61 https://doi.org/10.1016/j.ijid.2019.02.035.

Latent tuberculosis infection and renal transplantation - Diagnosis and management.  (2019) Krishnamoorthy, S., N. Kumaresan and A. Zumla  Int J Infect Dis 80S: S73-S76 https://doi.org/10.1016/j.ijid.2019.01.049.

Latent tuberculosis infection: diagnostic tests and when to treat.  (2019) Petersen, E., J. Chakaya, F. M. Jawad, G. Ippolito and A. Zumla  Lancet Infect Dis 19(3): 231-233 https://doi.org/10.1016/S1473-3099(19)30059-3.

Linezolid for drug-susceptible tuberculosis.  (2019) Ahmed, S., D. A. Moore, C. Nimmo, A. J. Nunn, T. A. Yates and T. B. J. C. North London  Lancet Infect Dis 19(4): 357 https://doi.org/10.1016/S1473-3099(19)30110-0.

Longitudinal analysis of serum cytokine profile among patients with tubercular multifocal serpiginoid choroiditis: a pilot study.  (2019) Agarwal, A., A. Deokar, R. Sharma, N. Singh, K. Aggarwal, S. Sharma, R. Singh, A. Sharma, K. Sharma, R. Agrawal, R. Bansal and V. Gupta  Eye (Lond) 33(1): 129-135 https://doi.org/10.1038/s41433-018-0157-5.

Lung Tissue Resident Memory T-Cells in the Immune Response to Mycobacterium tuberculosis.  (2019) Ogongo, P., J. Z. Porterfield and A. Leslie  Front Immunol 10: 992 https://doi.org/10.3389/fimmu.2019.00992.

Million Migrants study of healthcare and mortality outcomes in non-EU migrants and refugees to England: Analysis protocol for a linked population-based cohort study of 1.5 million migrants.  (2019) Burns, R., N. Pathak, I. Campos-Matos, D. Zenner, S. Vittal Katikireddi, M. C. Muzyamba, J. J. Miranda, R. Gilbert, H. Rutter, L. Jones, E. Williamson, A. C. Hayward, L. Smeeth, I. Abubakar, H. Hemingway and R. W. Aldridge  Wellcome Open Res 4: 4 https://doi.org/10.12688/wellcomeopenres.15007.1.

Mimicking in-vivo exposures to drug combinations in-vitro: anti-tuberculosis drugs in lung lesions and the hollow fiber model of infection.  (2019) Kloprogge, F., R. Hammond, K. Kipper, S. H. Gillespie and O. Della Pasqua  Sci Rep 9(1): 13228 https://doi.org/10.1038/s41598-019-49556-5.

Multidrug and Extensively Drug-resistant Tuberculosis: Epidemiology, Clinical Features, Management and Treatment.  (2019) Tiberi, S., A. Zumla and G. B. Migliori  Infect Dis Clin North Am 33(4): 1063-1085 https://doi.org/10.1016/j.idc.2019.09.002.

Multidrug-resistant tuberculosis.  (2019) Nyang'wa, B. T., C. Berry, K. Fielding and A. J. Nunn  Lancet 394(10195): 298-299 https://doi.org/10.1016/S0140-6736(19)30691-9.

Mycobacteria-Specific Mono- and Polyfunctional CD4+ T Cell Profiles in Children With Latent and Active Tuberculosis: A Prospective Proof-of-Concept Study.  (2019) Tebruegge, M., N. Ritz, S. Donath, B. Dutta, B. Forbes, V. Clifford, C. Zufferey, R. De Rose, R. M. Robins-Browne, W. Hanekom, S. M. Graham, T. Connell and N. Curtis  Front Immunol 10: 431 https://doi.org/10.3389/fimmu.2019.00431.

Mycobacterium tuberculosis transmission in an ethnically-diverse high incidence region in England, 2007-11.  (2019) Vynnycky, E., A. R. Keen, J. T. Evans, S. Khanom, P. M. Hawkey, R. G. White and I. Abubakar  BMC Infect Dis 19(1): 26 https://doi.org/10.1186/s12879-018-3585-8.

Mycobacterium tuberculosis-specific cytokine biomarkers for the diagnosis of childhood TB in a TB-endemic setting.  (2019) Sudbury, E. L., L. Otero, M. Tebruegge, N. L. Messina, C. Seas, M. Montes, J. Rios, S. Germano, K. Gardiner, V. Clifford, E. Gotuzzo and N. Curtis  J Clin Tuberc Other Mycobact Dis 16: 100102 https://doi.org/10.1016/j.jctube.2019.100102.

New drugs to treat difficult tuberculous and nontuberculous mycobacterial pulmonary disease.  (2019) Lee, S. F. K., B. E. Laughon, T. D. McHugh and M. Lipman  Curr Opin Pulm Med 25(3): 271-280 https://doi.org/10.1097/MCP.0000000000000570.

Osteoarcheological and biomolecular evidence of leprosy from an 11-13(th) century CE Muslim cemetery in Europe (Oroshaza, Southeast Hungary).  (2019) Balazs, J., Z. Rozsa, Z. Bereczki, A. Marcsik, B. Tihanyi, K. Karlinger, G. Poloskei, E. Molnar, H. D. Donoghue and G. Palfi  Homo 70(2): 105-118 https://doi.org/10.1127/homo/2019/1071.

The pathogenesis of tuberculous meningitis.  (2019) Davis, A. G., U. K. Rohlwink, A. Proust, A. A. Figaji and R. J. Wilkinson  J Leukoc Biol 105(2): 267-280 https://doi.org/10.1002/JLB.MR0318-102R.

PET/CT features of Extrapulmonary Tuberculosis at first clinical presentation - a cross-sectional observational (18)F-FDG imaging study across six countries.  (2019) Bomanji, J., R. Sharma, B. R. Mittal, S. Gambhir, A. Qureshy, S. M. F. Begum, D. Paez, M. Sathekge, M. Vorster, D. Sobic Saranovic, P. Pusuwan, V. Mann, S. Vinjamuri, A. Zumla, T. N. B. Pascual and T. B. C. International Atomic Energy Agency Extra-pulmonary  Eur Respir J https://doi.org/10.1183/13993003.01959-2019.

Plasma Biomarkers to Detect Prevalent or Predict Progressive Tuberculosis Associated With Human Immunodeficiency Virus-1.  (2019) Lesosky, M., M. X. Rangaka, C. Pienaar, A. K. Coussens, R. Goliath, S. Mathee, J. Mwansa-Kambafwile, G. Maartens, R. J. Wilkinson and K. A. Wilkinson  Clin Infect Dis 69(2): 295-305 https://doi.org/10.1093/cid/ciy823.

Prevalence, Safety and Long-Term Retention Rates of Biologics in Hong Kong from 2001 to 2015.  (2019) Ge, M., K. K. Man, C. S. Chui, E. W. Chan, I. C. Wong and X. Li  Drug Saf 42(9): 1091-1102 https://doi.org/10.1007/s40264-019-00844-z.

Projected population-wide impact of antiretroviral therapy-linked isoniazid preventive therapy in a high-burden setting.  (2019) Kendall, E. A., A. S. Azman, G. Maartens, A. Boulle, R. J. Wilkinson, D. W. Dowdy and M. X. Rangaka  AIDS 33(3): 525-536 https://doi.org/10.1097/QAD.0000000000002053.

Protocol for a cluster randomised control trial evaluating the efficacy and safety of treatment for latent tuberculosis infection in recent migrants within primary care: the CATAPuLT trial.  (2019) Burman, M., A. Copas, D. Zenner, V. Hickson, L. Gosce, D. Trathen, R. Ashcroft, A. R. Martineau, I. Abubakar, C. Griffiths and H. Kunst  BMC Public Health 19(1): 1598 https://doi.org/10.1186/s12889-019-7983-7.

Public health outcome of Tuberculosis Cluster Investigations, England 2010-2013.  (2019) Hamblion, E. L., A. Burkitt, M. K. Lalor, L. F. Anderson, H. L. Thomas, I. Abubakar, S. Morton, H. Maguire, S. R. Anderson and T. B. S. T. B. Public Health England  J Infect 78(4): 269-274 https://doi.org/10.1016/j.jinf.2018.12.004.

Publisher Correction: Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis.  (2019) Ardain, A., R. Domingo-Gonzalez, S. Das, S. W. Kazer, N. C. Howard, A. Singh, M. Ahmed, S. Nhamoyebonde, J. Rangel-Moreno, P. Ogongo, L. Lu, D. Ramsuran, M. de la Luz Garcia-Hernandez, T. K. Ulland, M. Darby, E. Park, F. Karim, L. Melocchi, R. Madansein, K. J. Dullabh, M. Dunlap, N. Marin-Agudelo, T. Ebihara, T. Ndung'u, D. Kaushal, A. S. Pym, J. K. Kolls, A. Steyn, J. Zuniga, W. Horsnell, W. M. Yokoyama, A. K. Shalek, H. N. Kloverpris, M. Colonna, A. Leslie and S. A. Khader  Nature 572(7768): E10 https://doi.org/10.1038/s41586-019-1458-y.

Quantitative Interferon Gamma Release Assay and Tuberculin Skin Test Results to Predict Incident Tuberculosis: A Prospective Cohort Study.  (2019) Gupta, R. K., M. Lipman, C. Jackson, A. Sitch, J. Southern, F. Drobniewski, J. J. Deeks, C. Y. Tsou, C. Griffiths, J. Davidson, C. Campbell, O. Stirrup, M. Noursadeghi, H. Kunst, P. Haldar, A. Lalvani and I. Abubakar  Am J Respir Crit Care Med https://doi.org/10.1164/rccm.201905-0969OC.

Recent Changes in Infectious Diseases in European Wildlife.  (2019) Yon, L., J. P. Duff, E. O. Agren, K. Erdelyi, E. Ferroglio, J. Godfroid, J. Hars, G. Hestvik, D. Horton, T. Kuiken, A. Lavazza, I. Markowska-Daniel, A. Martel, A. Neimanis, F. Pasmans, S. J. Price, F. Ruiz-Fons, M. P. Ryser-Degiorgis, F. Widen and D. Gavier-Widen  J Wildl Dis 55(1): 3-43 https://doi.org/10.7589/2017-07-172.

Reducing loss to follow-up during treatment for drug-resistant tuberculosis.  (2019) Abubakar, I. and M. Lipman  Eur Respir J 53(1) https://doi.org/10.1183/13993003.02268-2018.

Revolutionary new treatment for multidrug-resistant tuberculosis.  (2019) Meredith, S., A. Nunn and I. D. Russen  Lancet Infect Dis 19(6): 576-577 https://doi.org/10.1016/S1473-3099(19)30216-6.

Revolutionary new treatment regimens for multidrug-resistant tuberculosis.  (2019) McHugh, T. D., I. Honeyborne, M. Lipman and A. Zumla  Lancet Infect Dis 19(3): 233-234 https://doi.org/10.1016/S1473-3099(19)30060-X.

Riboswitches: choosing the best platform.  (2019) Arnvig, K. B.  Biochem Soc Trans 47(4): 1091-1099 https://doi.org/10.1042/BST20180507.

Risk Factors for Indeterminate Interferon-Gamma Release Assay for the Diagnosis of Tuberculosis in Children-A Systematic Review and Meta-Analysis.  (2019) Meier, N. R., T. Volken, M. Geiger, U. Heininger, M. Tebruegge and N. Ritz  Front Pediatr 7: 208 https://doi.org/10.3389/fped.2019.00208.

The Risk of Falsely Declaring Non-Inferiority of Novel Latent Tuberculosis Treatment in Large Trials.  (2019) Abubakar, I., F. G. Cobelens and M. X. Rangaka  Am J Respir Crit Care Med https://doi.org/10.1164/rccm.201911-2258ED.

Role of pharmacogenetics in rifampicin pharmacokinetics and the potential effect on TB-rifampicin sensitivity among Ugandan patients.  (2019) Mukonzo, J. K., A. Kengo, B. Kutesa, S. Nanzigu, A. Pohanka, T. D. McHugh, A. Zumla and E. Aklillu  Trans R Soc Trop Med Hyg https://doi.org/10.1093/trstmh/trz108.

Screening the population: Public information films in Scandinavian tuberculosis campaigns around 1950.  (2019) Thomson, C.  Journal of Scandinavian Cinema 9(1): 59-74 https://doi.org/10.1386/jsca.9.1.59_1.

A Shorter Regimen for Rifampin-Resistant Tuberculosis. Reply.  (2019) Nunn, A. J. and P. P. J. Phillips  N Engl J Med 381(11): e22 https://doi.org/10.1056/NEJMc1905782.

Should NICE reconsider the 2016 UK guidelines on TB contact tracing? A cost-effectiveness analysis of contact investigations in London.  (2019) Cavany, S. M., E. Vynnycky, C. S. Anderson, H. Maguire, F. Sandmann, H. L. Thomas, R. G. White and T. Sumner  Thorax 74(2): 185-193 https://doi.org/10.1136/thoraxjnl-2018-211662.

Smartphone-enabled video-observed versus directly observed treatment for tuberculosis: a multicentre, analyst-blinded, randomised, controlled superiority trial.  (2019) Story, A., R. W. Aldridge, C. M. Smith, E. Garber, J. Hall, G. Ferenando, L. Possas, S. Hemming, F. Wurie, S. Luchenski, I. Abubakar, T. D. McHugh, P. J. White, J. M. Watson, M. Lipman, R. Garfein and A. C. Hayward  Lancet 393(10177): 1216-1224 https://doi.org/10.1016/S0140-6736(18)32993-3.

Socio-demographic contributors to health and safety of mine workers in South Africa.  (2019) Pelders, J. and G. Nelson  Work 64(1): 67-76 https://doi.org/10.3233/WOR-192969.

Space-time clustering of recently-diagnosed tuberculosis and impact of ART scale-up: Evidence from an HIV hyper-endemic rural South African population.  (2019) Tomita, A., C. M. Smith, R. J. Lessells, A. Pym, A. D. Grant, T. de Oliveira and F. Tanser  Sci Rep 9(1): 10724 https://doi.org/10.1038/s41598-019-46455-7.

Spatial Network Mapping of Pulmonary Multidrug-Resistant Tuberculosis Cavities Using RNA Sequencing.  (2019) Dheda, K., L. Lenders, S. Srivastava, G. Magombedze, H. Wainwright, P. Raj, S. J. Bush, G. Pollara, R. Steyn, M. Davids, A. Pooran, T. Pennel, A. Linegar, R. McNerney, L. Moodley, J. G. Pasipanodya, C. T. Turner, M. Noursadeghi, R. M. Warren, E. Wakeland and T. Gumbo  Am J Respir Crit Care Med 200(3): 370-380 https://doi.org/10.1164/rccm.201807-1361OC.

A sputum sample processing method for community and mobile tuberculosis diagnosis using the Xpert MTB/RIF assay.  (2019) Gliddon, H. D., R. J. Shorten, A. C. Hayward and A. Story  ERJ Open Res 5(1) https://doi.org/10.1183/23120541.00165-2018.

STREAM: a pragmatic and explanatory trial for MDR-TB treatment.  (2019) Abubakar, I., S. Meredith, A. J. Nunn, P. P. J. Phillips and I. D. Rusen  Lancet Infect Dis 19(6): 575-576 https://doi.org/10.1016/S1473-3099(19)30215-4.

Studies on patients establish Crohn's disease as a manifestation of impaired innate immunity.  (2019) Segal, A. W.  J Intern Med 286(4): 373-388 https://doi.org/10.1111/joim.12945.

A Systematic Review and Meta-analysis of the Diagnostic Accuracy of Nucleic Acid Amplification Tests for Tuberculous Meningitis.  (2019) Pormohammad, A., M. J. Nasiri, T. D. McHugh, S. M. Riahi and N. C. Bahr  J Clin Microbiol 57(6) https://doi.org/10.1128/JCM.01113-18.

Towards a Future of Rapid, Low-Cost, Multiplexed Detection of Antimicrobial Resistance Markers for Tuberculosis and Other Pathogens.  (2019) Miller, B. S., H. D. Gliddon and R. A. McKendry  Clin Chem 65(3): 367-369 https://doi.org/10.1373/clinchem.2018.296715.

Towards optimal treatment for latent Mycobacterium tuberculosis infection.  (2019) Abubakar, I., J. Chakaya, M. Maeurer and A. Zumla  Lancet Respir Med 7(3): 195-197 https://doi.org/10.1016/S2213-2600(19)30036-0.

Toxicity related to standard TB therapy for pulmonary tuberculosis and treatment outcomes in the REMoxTB study according to HIV status.  (2019) Tweed, C. D., A. M. Crook, R. Dawson, A. H. Diacon, T. D. McHugh, C. M. Mendel, S. K. Meredith, L. Mohapi, M. E. Murphy, A. J. Nunn, P. P. J. Phillips, K. P. Singh, M. Spigelman and S. H. Gillespie  BMC Pulm Med 19(1): 152 https://doi.org/10.1186/s12890-019-0907-6.

Transmission of drug-resistant tuberculosis in HIV-endemic settings.  (2019) Khan, P. Y., T. A. Yates, M. Osman, R. M. Warren, Y. van der Heijden, N. Padayatchi, E. A. Nardell, D. Moore, B. Mathema, N. Gandhi, V. Eldholm, K. Dheda, A. C. Hesseling, V. Mizrahi, R. Rustomjee and A. Pym  Lancet Infect Dis 19(3): e77-e88 https://doi.org/10.1016/S1473-3099(18)30537-1.

TRAV1-2(+) CD8(+) T-cells including oligoconal expansions of MAIT cells are enriched in the airways in human tuberculosis.  (2019) Wong, E. B., M. C. Gold, E. W. Meermeier, B. Z. Xulu, S. Khuzwayo, Z. A. Sullivan, E. Mahyari, Z. Rogers, H. Kloverpris, P. K. Sharma, A. H. Worley, U. Lalloo, P. Baijnath, A. Ambaram, L. Naidoo, M. Suleman, R. Madansein, J. E. McLaren, K. Ladell, K. L. Miners, D. A. Price, S. M. Behar, M. Nielsen, V. O. Kasprowicz, A. Leslie, W. R. Bishai, T. Ndung'u and D. M. Lewinsohn  Commun Biol 2(1): 203 https://doi.org/10.1038/s42003-019-0442-2.

Trends and risk factors for death and excess all-cause mortality among notified tuberculosis patients in the UK: an analysis of surveillance data.  (2019) Pedrazzoli, D., K. Kranzer, H. L. Thomas and M. K. Lalor  ERJ Open Res 5(4) https://doi.org/10.1183/23120541.00125-2019.

A Trial of a Shorter Regimen for Rifampin-Resistant Tuberculosis.  (2019) Nunn, A. J., P. P. J. Phillips, S. K. Meredith, C. Y. Chiang, F. Conradie, D. Dalai, A. van Deun, P. T. Dat, N. Lan, I. Master, T. Mebrahtu, D. Meressa, R. Moodliar, N. Ngubane, K. Sanders, S. B. Squire, G. Torrea, B. Tsogt, I. D. Rusen and S. S. Collaborators  N Engl J Med 380(13): 1201-1213 https://doi.org/10.1056/NEJMoa1811867.

Tuberculin skin test - Outdated or still useful for Latent TB infection screening?  (2019) Gualano, G., P. Mencarini, F. N. Lauria, F. Palmieri, S. Mfinanga, P. Mwaba, J. Chakaya, A. Zumla and G. Ippolito  Int J Infect Dis 80S: S20-S22 https://doi.org/10.1016/j.ijid.2019.01.048.

Tuberculosis and leprosy associated with historical human population movements in Europe and beyond - an overview based on mycobacterial ancient DNA.  (2019) Donoghue, H. D.  Ann Hum Biol 46(2): 120-128 https://doi.org/10.1080/03014460.2019.1624822.

Tuberculosis disease in children and adolescents on therapy with anti-tumor necrosis factor-alpha agents: a collaborative, multi-centre ptbnet study.  (2019) Noguera-Julian, A., J. Calzada-HernAndez, F. Brinkmann, R. Basu Roy, O. Bilogortseva, M. Buettcher, I. Carvalho, V. Chechenyeva, L. Falcon, F. Goetzinger, C. Guerrero-Laleona, P. Hoffmann, M. Jelusic, T. Niehues, I. Ozere, F. Shackley, E. Suciliene, S. B. Welch, O. E. H. Sch, N. Ritz and M. Tebruegge  Clin Infect Dis https://doi.org/10.1093/cid/ciz1138.

Tuberculosis following renal transplantation in England, Wales and Northern Ireland: a national registry-based cohort study.  (2019) Gupta, R. K., G. Rosenberg, J. Eriksen, M. Lipman, C. Jackson, A. Roy, D. Zenner, C. Smith, M. Harber, C. Campbell and I. Abubakar  Eur Respir J 54(4) https://doi.org/10.1183/13993003.02245-2018.

Tuberculosis Genetic Epidemiology: A Latin American Perspective.  (2019) Woodman, M., I. L. Haeusler and L. Grandjean  Genes (Basel) 10(1) https://doi.org/10.3390/genes10010053.

The Tuberculosis Network European Trials group (TBnet) ERS Clinical Research Collaboration: addressing drug-resistant tuberculosis through European cooperation.  (2019) van Leth, F., F. Brinkmann, D. M. Cirillo, K. Dheda, R. Duarte, L. Guglielmetti, L. Kuksa, C. Lange, C. Mitnick, A. Skrahina, K. Zaman and G. Bothamley  Eur Respir J 53(1) https://doi.org/10.1183/13993003.02089-2018.

Urogenital tuberculosis - epidemiology, pathogenesis and clinical features.  (2019) Muneer, A., B. Macrae, S. Krishnamoorthy and A. Zumla  Nat Rev Urol 16(10): 573-598 https://doi.org/10.1038/s41585-019-0228-9.

Whole genome sequencing Mycobacterium tuberculosis directly from sputum identifies more genetic diversity than sequencing from culture.  (2019) Nimmo, C., L. P. Shaw, R. Doyle, R. Williams, K. Brien, C. Burgess, J. Breuer, F. Balloux and A. S. Pym  BMC Genomics 20(1): 389 https://doi.org/10.1186/s12864-019-5782-2.

Correction to: Whole genome sequencing Mycobacterium tuberculosis directly from sputum identifies more genetic diversity than sequencing from culture.  (2019) Nimmo, C., L. P. Shaw, R. Doyle, R. Williams, K. Brien, C. Burgess, J. Breuer, F. Balloux and A. S. Pym  BMC Genomics 20(1): 433 https://doi.org/10.1186/s12864-019-5841-8.

World Tuberculosis Day March 24th 2019 Theme: "It's TIME" - International Journal of Infectious Diseases Tuberculosis Theme Series.  (2019) Petersen, E., M. Rao, G. Ippolito, G. Gualano, J. Chakaya, F. Ntoumi, D. Moore, R. Allen, K. Gaskell, J. N. Ohd, M. P. Hergens, S. Krishnamoorthy, C. Ugarte-Gil, D. E. Kirwan, I. Honeyborne, T. D. McHugh, C. U. Koser, K. Kranzer, S. Tiberi, G. B. Migliori, Q. Mao, Y. Yang, S. P. Oliveira, R. F. Cardoso, A. Detjen, B. Marais, D. de Gijsel, C. F. von Reyn, L. Gosce, I. Abubakar, M. Maeurer and A. Zumla  Int J Infect Dis 80S: S1-S5 https://doi.org/10.1016/j.ijid.2019.02.024.

Xpert MTB/RIF Ultra for Tuberculosis Testing in Children: A Mini-Review and Commentary.  (2019) Atherton, R. R., F. V. Cresswell, J. Ellis, S. B. Kitaka and D. R. Boulware  Front Pediatr 7: 34 https://doi.org/10.3389/fped.2019.00034.


Other Outputs


Clinic-level variations in contact tracing outcomes: protocol for a cross-sectional study of variation and case-mix adjustment in London, UK. Lewer, D; Tamne, S; Nicholas, O; Anderson, C; Story, A; (2019)  UCL Collaborative Centre for Inclusion Health: London, UK. https://doi.org/10.14324/000.rp.10076891


India-UK Networking Partnership Workshops (Chennai and Delhi) February 2019 (Sarah Pett, MRC CTU at UCL, s.pett@ucl.ac.uk).


World TB Day 2019. 06 April 2019. N.G. Stoker

The Three Sisters and the Fourth Horseman. May 2019. N.G. Stoker

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