Nationwide and regional incidence of microbiologically confirmed pulmonary tuberculosis in South Africa, 2004-12: a time series analysis

Lancet Publication

Ananta Nanoo, MSc, Alane Izu, PhD, Nazir A Ismail, FCPath, Chikwe Ihekweazu, FFPH, Prof Ibrahim Abubakar, FRCP, David Mametja, MPH, Prof Shabir A Madhi, PhD
Abstract
South Africa has the highest incidence of tuberculosis in the world, largely resulting from a high population prevalence of HIV infection. We investigated the incidence of microbiologically confirmed pulmonary tuberculosis, and new cases of pulmonary tuberculosis registered for treatment, nationally and provincially in South Africa from 2004 to 2012, during which time there were changes in antiretroviral therapy (ART) coverage among individuals with HIV infection.
www.thelancet.com/journals/laninf/article/PIIS1473-3099(15)00147-4/abstract