Sainsbury Wellcome Centre for Neural Circuits and Behaviour


SWC Seminar: Professor Matthew Nolan

Start: Sep 20, 2018 12:00 PM
End: Sep 20, 2018 01:00 PM

Location: Ground floor Lecture Theatre, Sainsbury Wellcome Centre, 25 Howland Street, London W1T 4JG

Host: Andy Murray, Group Leader, SWC 

Matt Nolan Headshot

Talk Title: Cellular and circuit mechanisms for spatial computation

How do cells of the brain implement computations important for cognition? The well characterised spatial firing of grid cells and other neurons in the medial entorhinal cortex (MEC) make this structure an excellent model for investigation of cognitive circuitry. However, the mechanisms by which grid and other spatial codes are established and their roles in behaviour are unclear. I will discuss experiments that investigate molecularly defined cell types in the medial entorhinal cortex, their contribution to real world and virtual behaviours, and principles for their organisation into functional circuits.

Biography: Matt Nolan is Professor of Neural Circuits and Computation at the University of Edinburgh. His research group aims to understand how computations important for cognition are implemented by neural circuits in the brain. They have discovered principles for local and long-range organisation of circuits important for spatial computation, and have developed novel theoretical models for rate and temporal coding within these circuits. His current focus is on how memory and sensory stimuli are combined by these circuits. Before moving to Edinburgh, Matt was a postdoc at Columbia University working with Eric Kandel, where he contributed to discovery of cellular and behavioural roles of HCN1 channels, and prior to this he did his PhD at the University of Aberdeen, where he investigated biophysical properties of spinal sympathetic neurons.

No need to book, just turn up!