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UCL Division of Surgery and Interventional Science

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Centre for 3D Models of Health and Disease

We focus on engineering advanced tissue models.

The Centre for 3D models of health and disease consists of researchers active in developing biomimetic tissue models to study basic tissue biology and the impact of disease progression on tissue form and function. We cover a range of tissues from skeletal muscle to tendon and skin. The centre also works on biomimetic models of cancer, which we term tumouroids, engineering distinct cancer masses within complex stromal compartments to study cancer invasion and metastasis.  These models have been used to interrogate the action of chemotherapeutic drugs and other therapeutic modalities.