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UCL Division of Surgery and Interventional Science

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Centre for Tissue and Cell Research

Head: Dr Melanie Coathup

Within the Division of Surgery and Interventional Science based on the Stanmore Campus, the Centre for Tissue and Cell Research (CTCR) is co-located with the Royal National Orthopaedic Hospital and this facilitates a world-leading collaboration that integrates basic, translational and clinical science. 

Our Centre Head, Dr Coathup is also the Divisional Lead for Athena SWAN and Women in Science. 

Our aim

The aim of CTCR is to understand the causes of human musculoskeletal injury and disease and develop innovative therapies and technology to improve the quality of life of the people around us. The Centre currently consists of six academics, (Dr Melanie Coathup, Professor Helen Birch, Mr Andy Goldberg, Mr Panos Gikas and Dr Umber Cheema). From bench to beside, the Centre is currently exploring a number of novel approaches that range from investigating the organisation and function of cells, their components and extracellular products to clinical trials that examine surgical treatment for end-stage arthritis and the application of stem cells in patients suffering from tendon injury. The Centre provides a unique bio-innovative environment where scientists and clinicians investigate and apply science in the treatment and care of patients. 

Our key research themes 

  • Musculoskeletal Stem Cell Therapy
  • Tissue Repair and Regeneration
  • Tendon Degeneration, Ageing and Exercise
  • Biomimetic Tissue Engineering
  • Cytomechanics
  • Disease Modelling
  • Assay Development for Drug Delivery
  • Health Informatics Research
  • Treatment of Sports Injuries
  • Foot and Ankle Osteoarthritis 
  • Shoulder Osteoarthritis, Rotator Cuff Disease and Shoulder Instability
  • The Design and follow up of Ankle and Shoulder Prostheses