SLMS Academic Careers Office

Grand Challenges

36.  Rehabilitation strategies to improve balance and prevent falls in people with Charcot-Marie-Tooth disease

Supervisor Pair: Dr Gita Ramdharry and Professor Mary Reilly
Potential Student’s Home Department: MRC Centre for Neuromuscular Diseases, Department of Molecular Neuroscience, Institute of Neurology

Charcot-Marie-Tooth disease (CMT) is the most common inherited neuromuscular disorder and is a slow, progressive neuropathy manifesting with distal weakness and sensory loss. This PhD program will explore physical rehabilitation strategies, addressing key contributors to balance impairment. This will be done through (1) exploratory work ascertaining the link between falls history and physical activity; (2) home based training studies of focused exercise; (3) exploring the mechanical effect of ankle bracing on balance performance. The candidate will become proficient in instrumented posturography and 3D gait analysis techniques. Due to the clinical nature of this program and the inclusion of exercise training in the community, the candidate needs to be a qualified health professional, preferably a physiotherapist.