SLMS Academic Careers Office

Grand Challenges

2. Mind-body interactions influencing the outcome of treatment for epilepsy

Supervisor Pair: Professor Robert Horne and Professor Sanjay Sisodiya
Potential Student’s Home Department: School of Pharmacy, Department of Practice & Policy

Initial studies will explore the role of psychological factors (e.g. expectations and perceptions of illness and treatments, depression etc) in predicting clinical and behavioural outcomes in epilepsy (e.g. seizure frequency, drug levels, drug side effects). Ongoing parallel studies of other phenotypic characteristics, and genetic any epigenetic influences on drug response in epilepsy, will place psychological factors in context, and inform strategies for enhancing benefit through modification of the psychological factors influencing response to treatment.