Short courses


Current Challenges in Mammalian Cell Processing (MBI® Training, Bioprocess Industries)

  • 24 hours (approx)
  • 4 days


This four-day course provides an overview of the latest developments in mammalian cell processing.

You'll learn how to design next generation mammalian cell processes and evaluate the impact of emerging and disruptive technologies.

This course is for scientists, engineers and managers working in the biotech/biopharma sector.

This course is part of the Modular Training for the Bioprocess Industries programme (MBI®), run by the Department of Biochemical Engineering at UCL.

Course content and structure

Teaching is in small classes, with an emphasis on interactive problem solving and case studies.

Each day will cover the following topics:

Day 1

  • Historic perspective of mammalian cell culture
  • Rapid cell line development
  • The design of highly productive processes
  • Case study: strategies to optimise process economics 

    Day 2

    • Case study: from development to production
    • Challenges for mammalian cell culture analytics
    • Critical quality attributes of recombinant therapeutic
    • Scale-down approaches to bioprocess development
    • Use of mathematical models to improve bioprocesses

    Day 3

    • Engineering fundamentals and mixing in single-use bioreactors
    • Tutorial: technology transfer and scale translation
    • Developing the next generation monoclonal antibodies (mAbs) processing enabled by single-use
    • Workshop: single-use bioprocess economics
    • The impact of upstream production on downstream processing

    Day 4

    • Future technologies workshop

    Who the course is for

    This course is suitable for a range of people working in the the biotech/biopharma sectors, including:

    • molecular biologists
    • process engineers
    • cell biologists
    • analytical scientists
    • project managers
    • chief scientific officers

    Learning outcomes

    After completing this course you should be able to:

    • understand the fundamentals governing productivity and product quality at industrial scale
    • assess the suitability of single use technologies as a replacement for existing unit operations
    • develop robust and reliable scale down models to assist in process development and characterisation
    • understand the latest trends in cell line development and media formulation
    • understand process intensification, continuous bioprocessing and its current status and how to assess the impact of disruptive technologies
    • use mathematical models to enhance process understanding and improve activities in process optimisation 

    Costs and group bookings

    The standard price for this course is £1,750.

    Special prices are available for groups and SMEs. Contact mbi-training@ucl.ac.uk for more information.

    Course fees include materials, lunches and refreshments. Accommodation isn't included, but details of special rates at nearby hotels will be sent with your registration pack.

    Modular Training for the Bioprocess Industries (MBI®)

    The award-winning MBI® programme is a series of UCL-accredited short courses for people working in the bioprocessing industry. It's designed and delivered in collaboration with over 70 industrial experts.

    The programme provides flexible professional development training. You can choose to take standalone courses or combine them for a Certificate, Diploma or Master's qualification. It complements in-house training by providing broader perspectives for more informed decision-making.

    Courses have so far been delivered to over 900 individuals from more than 300 companies, 30% of which are non-UK, demonstrating its strong international impact.

    MBI® plays a central role in the department's knowledge-transfer activities. This ensures that cutting-edge research is undertaken to capture the value of integrating engineering with complex and fast-moving biology, which helps keep the global industry ahead in manufacturing.

    Benefits of MBI®

    By attending an MBI® course, you'll:

    • benefit from knowledge transfer and upskilling in core bioprocessing fundamentals and trends in industry
    • gain a deeper understanding of process options and engineering constraints
    • acquire the tools to optimise process performance and economics
    • learn about the latest technical and regulatory developments
    • have access to cutting edge research methodologies
    • network with sector leaders and subject matter experts
    • increase your flexibility, motivation, creativity and professional status

    Further information

    There is more information about the MBI® on the Department of Biochemical Engineering's website. If you have questions about fees or how to combine courses for a specific qualification, please email mbi-training@ucl.ac.uk

    Course team

    Dr Alexandros Kiparissides - Module Leader

    Dr Alexandros Kiparissides - Module Leader

    Alexandros is a Lecturer in Biochemical Engineering in the Department of Biochemical Engineering at UCL.

    Course information last modified: 8 Dec 2021, 11:30