Profiles of Current PhD Students
- Ibrahim Aldobiyan
NAME: Ibrahim Aldobiyan
EMAIL: ibrahim.aldobiyan.17@ucl.ac.uk
ACADEMIC BIOGRAPHY:
• Bachelor of Science (BSc) in Biochemistry, University of Leeds (2012-2015), Final Research Project: “Defining the structure of the icosahedral capsid of Cowpea mosaic virus (CPMV) using Cryo-EM, using two different image processing software. Introduced to a number of computational programs: SPIDER, RELION and UCSF Chimera”
• Master of Science (MSc) in Drug Design, University College London (2017-2018), Final Research Project: “Characterising the biochemical activities and structures of α1-Antitrypsin mutants in presence of a polymerisation inhibitor”
• PhD, University College London (Sept 2018 – Sept 2022), Research project: “The "...". Funded by King Saud University (KSU) through the Royal Embassy of Saudi Arabia Cultural Bureau in the UK & Ireland (UKSACB)
PROFESSIONAL BIOGRAPHY:
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PhD AIM:
The aim of my PhD is to utilise various biochemical, cellular biology and biophysical techniques with an emphasis on cryo-electron microscopy, in order to elucidate in molecular detail the polymerisation mechanism antitrypsin undergoes to form pathological polymers
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- Kamila Kamuda
NAME: Kamila Kamuda
EMAIL: k.kamuda@ucl.ac.uk
ACADEMIC BIOGRAPHY:
• Academic Profession degree in Chemical and Biotechnical Science, Business Academy Aarhus (Sept 2011 – Jan 2014), Final Research Project: “The role of Wnt-5a signalling on the newborn neurons migration in the Rostral Migratory Stream”
• Bachelor of Science (BSc) in Molecular Biology and Chemistry, Roskilde University (Sept 2014 – June 2016), Final Research Project "The interaction of the N and C terminal regions of the Bloom syndrome helicase with the Dissolvasome complex"
• Master of Science (MSc) in Human Biology, University of Copenhagen (Sept 2016 – Aug 2018), Final Research Project: “Characterization of the interaction between human CCT chaperonin and its substrates”
• PhD, University College London (Sept 2018 – Sept 2022), Research project: “The cellular consequences of polymer accumulation in alpha-1-antitrypsin deficiency elucidated in molecular detail”. PhD is funded by Wellcome Trust as part of the ISMB 4-year Interdisciplinary PhD programme in Structural, Chemical and Computational Biology
PROFESSIONAL BIOGRAPHY:
• Internship (Feb 2013 – Jan 2014), Research Assistant (Feb 2014 – Jun 2014) in Fluorescent Tissue Profiling group led by Dr Jan Mulder, Science for Life Laboratory, Department of Neuroscience, Karolinska Institutet
• Laboratory assistant (Nov 2014 – Oct 2015), Laboratory technician (Nov 2015 – Sept 2018) in Structural Molecular Biology group led by Prof. Guillermo Montoya, NNF Center for Protein Research, University of Copenhagen
• Demonstrator at Birkbeck College (Autumn term 2019/2020) for Practical Skills for Biosciences (BSc) and Molecular Microbiology (MSc) courses
PhD AIM:
The aim of my PhD is to investigate the effect of the polymerogenic mutations of α1-antitrypsin at the cellular and molecular level. I am using various approaches from cellular and molecular biology to understand the pathogenic consequence of the polymerization occurring in cells.
RESEARCH INTERESTS:
I am very interested in applying integrative structural biology to understand protein function at the molecular level and therefore I use a combination of techniques to answer my key research questions. The primary technique I use is electron microscopy, supported by protein crystallography, NMR and various biochemical assays.
Additionally, I am interested in developing computer programming skills and their implementation in my research, e.g. for data processing purposes.
PUBLICATIONS/CONFERENCES:
Wang D., Kamuda K., Montoya G. and Mesa P. The TRiC/CCT Chaperonin and Its Role in Uncontrolled Proliferation. Adv Exp Med Biol. 1243:21-40 (2020)
FENS meeting 2014 Milan, G017 poster (co-author), “Towards an antibody-based protein atlas of the mouse brain”
Instruct ERIC 2019 Alcalá de Henares, Madrid, poster presentation, “Structural effects of synthetic peptide incorporation in α1-antitrypsin ”
- Marina Nick
NAME: Marina Nick
EMAIL: marina.nick.18@ucl.ac.uk
ACADEMIC BIOGRAPHY:
• Bachelor of Science (BSc)
• Master of Science (MSc)
• PhD, University College London (Sept 2018 – Sept 2022), Research project: “The "...". Funded by .....
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- Sarah Lowen
NAME: Sarah Lowen
EMAIL: s.lowen@ucl.ac.uk
ACADEMIC BIOGRAPHY:
• Bachelor of Science (BSc)
• Master of Science (MSc)
• PhD, University College London (Sept 2018 – Sept 2022), Research project: “The "...". Funded by .....
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- Sarah Vickers
NAME: Sarah Vickers
EMAIL: s.vickers@ucl.ac.uk
ACADEMIC BIOGRAPHY:
• Bachelor of Science (BSc)
• Master of Science (MSc)
• PhD, University College London (Sept 2018 – Sept 2022), Research project: “The "...". Funded by .....
PROFESSIONAL BIOGRAPHY:
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- FORMER STUDENTS
FORMER PhD STUDENTS
Name Email Thesis Sarah Faull s.faull@ucl.ac.uk Emma Elliston e.elliston@alumni.ucl.ac.uk Anwen Brown a.brown@ucl.ac.uk Alistair Jagger a.jagger@ucl.ac.uk FORMER MASTERS STUDENTS
Name | Thesis | |
Sarah Lowen | ||
Ayah | ||
Tobias Petersen | ||
Ibrahin Aldobiyan | ||
Harry-Jack Mann | ||
Lathan Liu | ||
Arjun Scott Nanda | arjun.nanda.15@alumni.ucl.ac.uk | |
Josh Wort | ||
Magd Badoui | ||
Ragda Ibrahem | ||
Sun Congxin | ||
Mandy Wan | ||
Erini Kevrekidou | ||
Jinq He | ||
Maximillian Liedtke | ||
Michael Poeschla | m.poeschla.16@alumni.ucl.ac.uk | |
F |