Safer precision radiotherapies that will be able to cure more cancers with fewer side-effects will be available within five years under ambitious new plans for research and treatment at the UCL Cancer Institute and University College London Hospitals (UCLH) NHS Foundation Trust.
Publication date: 22 April 2016
Universities and Science Minister Jo Johnson has sought to reassure researchers that the proposed restrictions preventing the use of government grants to ‘lobby’ government will not apply to funding from the Research Councils, HEFCE or the National Academies.
Publication date: 21 April 2016
A drug currently being trialled in cancer patients could also be used to treat an often incurable condition that can cause painful blood vessel overgrowths inside the skin, finds new research in mice led by UCL, Memorial Sloan Kettering (MSK) Cancer Center in New York and the Bellvitge Biomedical Research Institute (IDIBELL) in Barcelona.
Publication date: 31 March 2016
A new drug to treat the muscle wasting disease inclusion body myositis (IBM) reverses key symptoms in mice and is safe and well-tolerated in patients, finds a new study led by the Medical Research Council (MRC) Centre for Neuromuscular Diseases at UCL and the University of Kansas Medical Center.
Publication date: 24 March 2016
The reason why the body’s immune cells cause so much damage and can’t regulate themselves in patients with lupus has been revealed in a UCL study published in the journal Immunity, a finding which could lead to more effective ways of treating lupus.
Publication date: 9 March 2016
Scientists at UCL have made a groundbreaking discovery in understanding how the genetic complexity of tumours can be recognised and exploited by the immune system, even when the disease is at its most advanced stages.
Publication date: 4 March 2016
A group of drugs being developed to treat mood disorders could also relieve chronic pain, finds new UCL research funded by the Medical Research Council.
Publication date: 11 February 2016
HIV drug resistance to tenofovir, an antiretroviral drug vital to most
modern HIV treatment and prevention strategies, is surprisingly and worryingly common
according to a large study led by UCL and funded by the Wellcome Trust.
Publication date: 29 January 2016
Two papers from UCL show that having early chemotherapy improves survival for men with prostate cancer. The papers, published in the Lancet and Lancet Oncology, report the results from the STAMPEDE clinical trial and a meta-analysis.
Publication date: 22 December 2015
New results from the world’s biggest ovarian cancer screening trial led by UCL suggest that screening based on an annual blood test may help reduce the number of women dying from the disease by around 20%.
Publication date: 17 December 2015
A potential new approach to treat systemic amyloidosis, invented at UCL and being developed by GlaxoSmithKline (GSK), marks the start of a successful and innovative academic-industry collaboration.
Publication date: 16 July 2015
UCL has successfully coordinated a £16 million bid to work with the Medical Research Council (MRC), GSK and four other universities to improve scientists’ understanding of inflammatory and fibrotic diseases that present a serious burden to patients.
Publication date: 15 July 2015
A landmark study that has been following a group of people since their birth in the same week in March 1946 is now turning its focus to the risk factors and early signs of dementia.
Publication date: 14 July 2015
More than a third of overweight or obese teenagers don’t see themselves as being too heavy and think their weight is about right, according to a UCL study published today in the International Journal of Obesity.
Publication date: 9 July 2015
A new technique for treating polycystic kidney disease has been identified by researchers based at the UCL Institute of Child Health. Published in the Journal of the American Society of Nephrology, the treatment, which involves targeting tiny blood and lymphatic vessels inside the kidneys, is shown to improve renal function and slow progression of disease in mice.
Publication date: 3 June 2015
Women with advanced ovarian cancer have fewer side effects and tend to have a better quality of life if given chemotherapy before surgery, according to a Cancer Research UK funded study published in The Lancet.
Publication date: 20 May 2015
DNA damage caused by smoking can be detected in cheek swabs, finds research published today in JAMA Oncology. The study provides evidence that smoking induces a general cancer program that is also present in cancers which aren’t usually associated with it – including breast and gynaecological cancers.
Publication date: 14 May 2015
Tuberculosis (TB) disease rates in some parts of London are as high as in Sub-Saharan Africa, and drug-resistant strains are becoming increasingly common. These require specific treatments, and if doctors know that a bug is resistant they can start therapy earlier, often leading to better outcomes.
Publication date: 13 May 2015
A new screening method can detect twice as many women with ovarian cancer as conventional strategies, according to the latest results from the largest trial of its kind led by UCL.
Publication date: 5 May 2015
The human immune system can handle large bursts of HIV activity and so it should be possible to cure HIV with a ‘kick and kill’ strategy, finds new research led by UCL, University College London Hospitals (UCLH) NHS Foundation Trust, the University of Oxford and the University of North Carolina at Chapel Hill.
Publication date: 13 April 2015
Scientists have revealed a brand new function for one of the first cancer genes ever discovered – the retinoblastoma gene – in a finding that could open up exciting new approaches to treatment.
Publication date: 27 March 2015
Weight discrimination is linked to significantly lower quality of life, and accounts for approximately 40% of the negative psychological effects associated with obesity, finds new UCL research funded by Cancer Research UK.
Publication date: 24 March 2015
Many people in the UK feel a strong sense of regional identity, and it now appears that there may be a scientific basis to this feeling, according to a landmark new study into the genetic makeup of the British Isles.
Publication date: 19 March 2015
People who worry about cancer are more likely to want to get screened for colon cancer, but feeling uncomfortable at the thought of cancer makes them less likely to actually go for the test, finds new UCL-led research.
Publication date: 29 January 2015
A partnership involving UCL has been awarded £14M to accelerate access to simple self-tests in African countries. Self-testing for HIV using rapid diagnostic kits is becoming increasingly widely used, allowing high-risk people to test their own HIV status in private.
Publication date: 4 December 2014