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Studying Human Sciences at UCL
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The signaling protein CD38 is essential for early embryonic development
CD38 is a multifunctional protein possessing ADP-ribosyl cyclase activity responsible for both the synthesis and the degradation of several Ca(2+)-mobilizing second messengers. Although a variety of functions have been ascribed to CD38, such as immune responses, insulin secretion, and social behavior in adults, nothing is known of its role during embryonic development when Ca(2+) signals feature prominently. Here, we report the identification and functional expression of CD38 from Xenopus laevis, a key model organism for the study of vertebrate development.
A BMP pathway regulates cell fate allocation along the sea urchin animal-vegetal embryonic axis
To examine whether a BMP signaling pathway functions in specification of cell fates in sea urchin embryos, we have cloned sea urchin BMP2/4, analyzed its expression in time and space in developing embryos and assayed the developmental consequences of changing its concentration through mRNA injection experiments.
A digital dissection of two teleost fishes: comparative functional anatomy of the cranial musculoskeletal system in pike
Advances in X-ray computed tomography (CT) have led to a rise in the use of non-destructive imaging methods in comparative anatomy. Among these is contrast-enhanced CT scanning, which employs chemical stains to visualize soft tissues.
Tooth replacement in Manidens condorensis: baseline study
The Palaeontological Association Dental replacement in Heterodontosauridae has been debated over the last five decades primarily on indirect evidence, such as the development of wear facets and the position of erupted teeth.
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