The PRIMROSE Programme of research

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Prediction and management of cardiovascular disease risk for people with severe mental illnesses: A research programme and trial in primary care (PRIMROSE)

The PRIMROSE project is a five year programme of research containing three related work packages. We will bring the evidence from each work package together to finalise a service for reducing cardiovascular disease risk in people with severe mental illnesses in primary care. The service will involve practice nurses working closely with people with severe mental illnesses to reduce their risk of cardiovascular disease. The cost effectiveness of the service will be assessed in a cluster randomised trial.

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>>Work Package 1: Developing a risk score tool

The aim of work package one is to develop and validate a cardiovascular risk prediction tool which is specific to people with severe mental illnesses

>>Work Package 2: Developing an intervention and training programme

The development phase of the programme involves reviewing the best available evidence of effective behavioural and pharmacological interventions for reducing cardiovascular disease risk in people with severe mental illnesses. We will also run focus groups with primary care staff, service users, carers and community mental health team workers to inform the development of a new package of care to reduce cardiovascular risk in people with severe mental illnesses.

>>Work Package 3 - A clinical trial in primary care

The final phase of the programme involves a cluster randomised controlled trial to test the cost-effectiveness of an intervention to reduce cardiovascular disease risk in people with severe mental illnesses in primary care. We will recruit 380 patients from 38 GP practices across the UK. Recruitment is due to begin in October 2013.

Page last modified on 20 mar 14 16:29