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Links to published Priment research collaborations (both trial related and non-trial specific), split by year of publication.

2024

NIDUS Family: A psychosocial goal-setting and manualised support intervention for independence in dementia (NIDUS-Family) versus goal setting and routine care: a single-masked, phase 3, superiority, randomised controlled trial

 

2023

PETAL: Estimation of the minimal clinically important difference on the Aberrant Behaviour Checklist–Irritability (ABC-I) for people with intellectual disabilities who display aggressive challenging behaviour: A triangulated approach

ORBIT:  Online remote behavioural intervention for tics in 9- to 17-year-olds: the ORBIT RCT with embedded process and economic evaluation

Community Navigator: Randomised controlled trial of the Community Navigator programme to reduce loneliness and depression for adults with treatment-resistant depression in secondary community mental health services: trial protocol

Antler: Clinical factors associated with relapse in depression in a sample of UK primary care patients who have been on long-term antidepressant treatment

Radar:  Antipsychotic dose reduction and discontinuation versus maintenance treatment in people with schizophrenia and other recurrent psychotic disorders in England (the RADAR trial): an open, parallel-group, randomised controlled trial

Petal: Stakeholder views on the barriers and facilitators of psychosocial interventions to address reduction in aggressive challenging behaviour in adults with intellectual disabilities

Core: Cost-effectiveness of peer-supported self-management for people discharged from a mental health crisis team: methodological challenges and recommendations

Physio4FMD: COVID-19 and the Physio4FMD trial: Impact, mitigating strategies and analysis plans

Antler: Reliability of the retrospective Clinical Interview Schedule Revised (rCIS-R) to assess relapse in depression in primary care patients

 

2022

PETAL: Estimation of the minimal clinically important difference on the Aberrant Behaviour Checklist–Irritability (ABC-I) for people with intellectual disabilities who display aggressive challenging behaviour: A triangulated approach

ORBIT: The COVID-19 pandemic and its impact on tic symptoms in children and young people: a prospective cohort study

HomeHealth: Clinical and cost-effectiveness of a personalised health promotion intervention enabling independence in older people with mild frailty (‘HomeHealth’) compared to treatment as usual: Study protocol for a Randomised Controlled Trial

PD-Care: Systematic review and meta-analysis of clinical effectiveness of self-management interventions in Parkinson’s disease

PiPS2: The accuracy of clinician predictions of survival in the Prognosis in Palliative care Study II (PiPS2): A prospective observational study

NIDUS: Process evaluation of the New Interventions for Independence in Dementia study (NIDUS) family stream randomised controlled trial

NIDUS: Time to reflect is a rare and valued opportunity: A pilot of the NIDUS professional dementia training intervention for home care workers during the COVID-19 pandemic

2021

RADAR: How do participants in clinical trials compare with other patients with schizophrenia? 

The CORE Programme: Trajectories of loneliness and objective social isolation and associations between persistent loneliness and self-reported personal recovery in a cohort of secondary mental health service users in the UK

ORBIT: Therapist-supported online remote behavioural intervention for tics (ORBIT) in children and adolescents: A single-blind randomised controlled trial

BHiRCH: A complex intervention to reduce avoidable hospital admissions in nursing homes: a research programme including the BHiRCH-NH pilot cluster RCT

Shape Up-LD: A manualised weight management programme for adults with mild–moderate intellectual disabilities affected by excess weight: A randomised controlled feasibility trial (Shape Up‐LD)

MenSS & PBS: Joint longitudinal models for dealing with missing at random data in trial-based economic evaluations

APPLE-Tree: Social connectedness and dementia prevention: Pilot of the APPLE-Tree video-call intervention during the Covid-19 pandemic

Systematic Review: Interactive digital interventions for prevention of sexually transmitted HIV: systematic review and meta-analyses

PREDICTD: Use of a personalised depression intervention in primary care to prevent anxiety: a secondary study of a cluster randomised trial

Remote primary care consultations for people living with dementia during the COVID-19 pandemic: experiences of people living with dementia and their carers

COVID-19 infection and attributable mortality in UK care homes: Cohort study using active surveillance and electronic records (March-June 2020)

Strategies to improve retention in randomised trials. Cochrane Database of Systematic Reviews 2021

Life under lockdown and social restrictions - the experiences of people living with dementia and their carers during the COVID-19 pandemic in England 

Methodology: A comparison of methods for analysing multiple outcome measures in randomised controlled trials using a simulation study

EPICC-ID: My Son Can’t Socially Distance or Wear a Mask: How Families of Preschool Children with Severe Developmental Delays and Challenging Behavior Experienced the COVID-19 Pandemic

ORBIT: Therapist-Supported Online Remote Behavioural Intervention for Tics in Children and Adolescents in England (ORBIT): a multicentre, parallel group, single-blind, randomised controlled trial

ANTLER: Cost-Utility Analysis of Discontinuing Antidepressants in England Primary Care Patients Compared with Long-Term Maintence: The ANTLER Study

ANTLER: Antidepressant medication to prevent depression relapse in primary care: the ANTLER RCT

Interactive digital interventions for prevention of sexually transmitted HIV: systematic review and meta-analyses

PiPS2: The Prognosis in Palliative care Study II (PiPS2): study protocol for a multi-centre, prospective, observational, cohort study

LOGIC: Longitudinal Outcomes of Gender Identity in Children (LOGIC) protocol for a prospective longitudinal cohort study of children referred to the UK gender identity development service

ANTLER: Maintenance or Discontinuation of Antidepressants in Primary Care

PiPS2: Study recruitment factors in advanced cancer: the Prognosis in Palliative care Study II (PiPS2) - a multicentre, prospective, observational cohort project

PiPS2: Prognostic models of survival in patients with advanced incurable cancer: the PiPS2 observational study

PiPS2: Comparing the performance of the palliative prognostic (PaP) score with clinical predictions of survival: A systematic review

LOGIC: Longitudinal Outcomes of Gender Identity in Children (LOGIC): study protocol for a retrospective analysis of the characteristics and outcomes of children referred to specialist gender services in the UK and the Netherlands

NIDUS: Clinical and cost-effectiveness of a New psychosocial intervention to support Independence in Dementia (NIDUS-Family) for family carers and people living with dementia in their own homes: A randomised controlled trial

2020

Contraception Choices: An interactive website for informed contraception choice: randomised evaluation of Contraception Choices

PriDem: Mapping post-diagnostic dementia care in England: an e-survey

PriDem: What works in managing complex conditions in older people in primary and community care? A state-of-the-art review

LiGHT: Efficacy of Repeat Selective Laser Trabeculoplasty in Medication-Naive Open-Angle Glaucoma and Ocular Hypertension during the LiGHT Trial

CanTalk: A pragmatic approach to measuring adherence in treatment delivery in psychotherapy

PROMISE: Improving the assessment and management of obesity in UK children and adolescents: the PROMISE research programme including a RCT

PBS: Staff training in positive behaviour support for behaviour that challenges in people with intellectual disability: cost-utility analysis of a cluster randomised controlled trial

The Marie Curie Dementia Research Programme: Healthcare utilization and monetary costs associated with agitation in UK care home residents with advanced dementia: a prospective cohort study

MARQUE: Becoming or remaining agitated: the course of agitation in people with dementia living in care homes: the English longitudinal Managing Agitation and Raising Quality of Life (MARQUE) study Journal of Alzheimer’s Disease

The CORE Programme: The CORE Service Improvement Programme for mental health Crisis Resolution Teams: results from a cluster-randomised trial

The MARQUE Project: Comparing proxy rated quality of life of people living with dementia in care homes

VIDAL: High-dose oral vitamin D supplementation and mortality in people aged 65-84 years: the VIDAL cluster feasibility RCT of open versus double-blind individual randomisation

CanTalk: Effectivness of cognitive and bahvauiour therapy for depression in advanced cancer: randomised controlled trial 

Primrose: Is there an association between perceived social support and cardiovascular health behaviours in people with severe mental illnesses? 

PriDem: Effectiveness of different post-diagnostic dementia care models delivered by primary care: a systematic review

BID: One-to-one befriending for people with intellectual disability and symptoms of depression: protocol for a pilot randomised controlled trial

The CORE Programme: Loneliness as a predictor of outcomes in mental disorders among people who have experienced a mental health crisis: a 4-month prospective study

The CORE Programme: The CORE Service Improvement Programme for mental health Crisis Resolution Teams: results from a cluster-randomised trial 

The CORE Programme: Epidemiology of loneliness in a cohort of UK mental health community crisis service users 

PriDem: Task-shifted approach to post-diagnostic dementia support: a qualitative study exploring professional views and experiences 

PriDem: Implementing post diagnostic dementia care in primary care: A mixed-methods systematic review

The MARQUE Project: Burnout in UK care home staff and its effect on staff turnover: MARQUE (Managing Agitation and Raising Quality of Life) English national care home longitudinal survey 

The CORE Programme: Loneliness as a predictor of outcomes in mental disorders among people who have experienced a mental health crisis: a 4-month prospective study 

Primrose: Exploring how health behaviours are supported and changed in people with severe mental illness (SMI): A qualitative study of a cardiovascular risk reducing intervention in Primary Care in England

BHiRCH: A pilot cluster randomised trial of an evidence-based intervention to reduce avoidable hospital admissions in nursing home residents (the Better Health in Residents in Nursing Homes - BHiRCH-NH study) 

The MARQUE Project: Development, feasibility and acceptability of an intervention to improve care for agitation in people living in nursing homes with dementia nearing the end of life 

VIP: The clinical and cost-effectiveness of a Victim Improvement Package (VIP) for the reduction of chronic symptoms of depression or anxiety in older victims of common crime (the VIP trial): study protocol for a randomised controlled trial

NIDUS: A mixed-methods feasibility study of a goal-focused manualised intervention to support people with dementia to stay living independently at home: NIDUS (New Interventions for Independence in Dementia Study)

HipDys: Parents' expectations and experiences of the 6-week baby check: a qualitative study in primary care

HipDys: Study protocol for evaluation of aid to diagnosis for developmental dysplasia of the hip in general practice: controlled trial randomised by practice

Exploring how triads of people living with dementia, carers and health care professionals function in dementia health care: A systematic qualitative review and thematic synthesis

Overcoming barriers to a diagnosis of dementia: Can we do it?

EPICC-ID: Clinical and cost effectiveness of a parent mediated intervention to reduce challenging behaviour in pre-schoolers with moderate to severe intellectual disability (EPICC-ID) study protocol: a multicentre, parallel-group randomised controlled trial

2019

RADAR: Randomised controlled trial of gradual antipsychotic reduction and discontinuation in people with schizophrenia and related disorders: the RADAR trial (Research into Antipsychotic Discontinuation and Reduction) 

Physio4FMD: Physio4FMD: protocol for a multicentre randomised controlled trial of specialist physiotherapy for functional motor disorder

Circle: Clinical and cost-effectiveness of contingency management for cannabis use in early psychosis: the CIRCLE randomised clinical trial

LiGHT: Selective laser trabeculoplasty versus drops for newly diagnosed ocular hypertension and glaucoma: the LiGHT RCT

CORE: Epidemiology of loneliness in a cohort of UK mental health community crisis service users 

RADAR: Mental health professionals’ views and experiences of antipsychotic reduction and discontinuation

ANTLER:  A randomised controlled trial assessing the use of citalopram, sertraline, fluoxetine and mirtazapine in preventing relapse in primary care patients who are taking long term maintenance antidepressants (ANTLER: ANTidepressants to prevent reLapse in dEpRession): trial protocol 

CanTalk: Manualised cognitive-behavioural therapy in treating depression in advanced cancer: the CanTalk RCT

PRIMROSE: Primary care management of cardiovascular risk for people with severe mental illnesses: the Primrose research programme including cluster RCT

LiGHT: Primary Selective Laser Trabeculoplasty for Open-Angle Glaucoma and Ocular Hypertension: Clinical Outcomes, Predictors of Success, and Safety from the Laser in Glaucoma and Ocular Hypertension Trial

SAFFRON: Stepped approach to improving sexual function after gynaelogical cancer: the SAFFRON feasibility RCT

The MARQUE Project: Clinical and cost-effectiveness of the Managing Agitation and Raising QUality of LifE in dementia (MARQUE) intervention for agitation in people with dementia in care homes: a single-blind cluster randomised controlled trial

CanACT: Acceptance and commitment therapy for adults with advanced cancer (CanACT): A feasibility randomised controlled trial

ORBIT: Investigating a therapist-guided, parent-assisted remote digital behavioural intervention for tics in children and adolescents – ‘Online Remote Behavioural Intervention for Tics’ (ORBIT) Trial: protocol of an internal pilot study and single-blind randomised controlled trial 

The MARQUE Project: Healthcare resource utilisation and costs of agitation in people with dementia living in care homes in England- the Managing Agitation and Raising QUality of LifE in Dementia (MARQUE) study

The MARQUE Project: Clinical and cost-effectiveness of the Managing Agitation and Raising QUality of LifE in dementia (MARQUE) intervention for agitation in people with dementia in care homes: a single-blind cluster randomised controlled trial

Circle: A contingency management intervention to reduce cannabis use and time to relapse in early psychosis: the CIRCLE RCT

Methodology: Methods to adjust for multiple comparisons in the analysis and sample size calculation of randomised controlled trials with multiple primary outcomes

predicT-EVAL: Family physicians' views on participating in prevention of major depression. The predictD-EVAL qualitative study

TOSCA: Barriers to recruitment when conducting a commissioned randomised controlled trial of medication versus psychological therapy for generalised anxiety disorder: some lessons learned

ReDIT: Dynamic interpersonal therapy for moderate to severe depression: a pilot randomized controlled and feasibility trial

PBS: Challenging behaviour, epilepsy and intellectual disability: A secondary analysis of findings from a randomised controlled trial

LiGHT: Selective laser trabeculoplasty versus eye drops for first-line treatment of ocular hypertension and glaucoma (LiGHT): a multicentre randomised controlled trial

The CORE Programme: Crisis resolution teams for people experiencing mental health crises: the CORE mixed-methods research programme including two RCTs

BHiRCH: Evidence-based intervention to reduce avoidable hospital admissions in care home residents (the Better Health in Residents in Care Homes- BHiRCH study); protocol for a pilot cluster randomised trial 

Meta-Analysis: Pharmacological treatments for generalised anxiety disorder: a systematic review and network meta-analysis

APPLE-Tree: APPLE-Tree (Active Prevention in People at risk of dementia: Lifestyle, bEhaviour change and Technology to REducE cognitive and functional decline) programme: protocol

START: Clinical effectiveness of START (STrAtegies for RelaTives) psychological intervention for family carers and the effects on cost of care for people with dementia: six year follow-up of a randomised controlled trial

2018

The MARQUE Project: Carer coping and resident agitation as predictors of quality of life in care home residents living with dementia: MARQUE (Managing Agitation and Raising Quality of Life) English national care home prospective cohort study

HeLP-Diabetes: Cost-Effectiveness of Facilitated Access to a Self-Management Website, Compared to Usual Care, for Patients With Type 2 Diabetes (HeLP-Diabetes): Randomized Controlled Trial

PBS: Clinical and cost effectiveness of staff training in the delivery of Positive Behaviour Support (PBS) for adults with intellectual disabilities, autism spectrum disorder and challenging behaviour - randomised trial

HELP: Cost-effectiveness of a community-delivered multicomponent intervention compared with enhanced standard care of obese adolescents: cost-utility analysis alongside a randomised controlled trial (the HELP trial)

PRIMROSE: Clinical and cost-effectiveness of an intervention for reducing cholesterol and cardiovascular risk for people with severe mental illness in English primary care: a cluster randomised controlled trial 

AMICUS: Amisulpride augmentation of clozapine for treatment-refractory schizophrenia: a double-blind, placebo-controlled trial

The MARQUE Project: Relationship between speaking English as a second language and agitation in people with dementia living in care homes: results from the MARQUE (Managing Agitation and Raising Quality of life) English national care home survey

PBS: Clinical outcomes of staff training in positive behaviour support to reduce challenging behaviour in adults with intellectual disability: cluster randomised controlled trial

PBS: Positive behaviour support training for staff for treating challenging behaviour in people with intellectual disabilities: a cluster RCT

The MARQUE Project: Do care homes deliver person-centred care? A cross-sectional survey of staff-reported abusive and positive behaviours towards residents from the MARQUE (Managing Agitation and Raising Quality of Life) English national care home survey

HAUS: Self-sampling kits to increase HIV testing among black Africans in the UK: the HAUS mixed-methods study

10 Top Tips: Cost-effectiveness of habit-based advice for weight control versus usual care in general practice in the Ten Top Tips (10TT) trial: economic evaluation based on a randomised controlled trial

The CORE Programme: Peer-supported self-management for people discharged from a mental health crisis team: a randomised controlled trial

HeLP-Diabetes: A web-based self-management programme for people with type 2 diabetes: the HeLP-Diabetes research programme including RCT

PiPS2: The Prognosis in Palliative care Study II (PiPS2): study protocol for a multi-centre, prospective, observational, cohort study

predicdT-CCRT: A personalized intervention to prevent depression in primary care: cost-effectiveness study nested into a clustered randomized trial

2017

Start2Quit: Cost-effectiveness of personal tailored risk information and taster sessions to increase the uptake of the NHS stop smoking services: the Start2quit randomized controlled trial

PANDA: A randomised controlled trial assessing the severity and duration of depressive symptoms associated with a clinically significant response to sertraline versus placebo, in people presenting to primary care with depression (PANDA trial): study protocol for a randomised controlled trial

CORE:  A randomised controlled trial of the clinical and cost-effectiveness of a peer delivered self-management intervention to prevent relapse in crisis resolution team users: study protocol

LiGHT: The laser in glaucoma and ocular hypertension (LiGHT) trial. A multicentre randomised controlled trial: baseline patient characteristics

The Marie Curie Dementia Research Programme: Living and dying with advanced dementia: a prospective cohort study of symptoms, service use and care at the end of life

LiGHT:  Laser in Glaucoma and Ocular Hypertension (LiGHT) Trial. A multicentre, randomised controlled trial: design and methodology

HeLP-Diabetes: Web-based self-management support for people with type 2 diabetes (HeLPDiabetes): randomised controlled trial in English primary care

HeLP: A community-based motivational personalised lifestyle intervention to reduce BMI in obese adolescents: results from the Healthy Eating and Lifestyle Programme (HELP) randomised controlled trial

The Marie Curie Dementia Research Programme: Implementing the compassion intervention, a model for integrated care for people with advanced dementia towards the end of life in nursing homes: a naturalistic feasibility study

Start2Quit: Effectiveness of personalised risk information and taster sessions to increase the uptake of smoking cessation services (Start2quit): a randomised controlled trial

Start2Quit: a randomised clinical controlled trial to evaluate the effectiveness and cost-effectiveness of using personal tailored risk information and taster sessions to increase the uptake of the NHS Stop Smoking Services

PBS: An exploratory factor analysis and construct validity of the resident choice assessment scale with paid carers of adults with intellectual disabilities and challenging behavior in community settings

AMICUS: Amisulpride Augmentation of Clozapine for Treatment-Refractory Schizophrenia: The AMICUS Study

KIWE: Ketogenic diet in the treatment of epilepsy in children under the age of 2 years: study protocol for a randomised controlled trial 

EBI-LD: A feasibility randomised controlled trial of extended brief intervention for alcohol misuse in adults with mild to moderate intellectual disabilities living in the community; The EBI-LD study

PRIMROSE: Effectiveness and cost-effectiveness of a cardiovascular risk prediction algorithm for people with severe mental illness (PRIMROSE) 

The Marie Curie Dementia Research Programme: Experiences of end of life amongst family carers of people with advanced dementia: longitudinal cohort study with mixed methods

EBI-LD: Development and evaluation of a manual for extended brief intervention for alcohol misuse for adults with mild to moderate intellectual disabilities living in the community: The EBI‐LD study manual

AMICUS: AMIsulpride augmentation in Clozapine-Unresponsive Schizophrenia (AMICUS): a double-blind, placebo-controlled, randomised trial of clinical effectiveness and cost-effectiveness 

10 Top Tips: The role of self-regulatory skills and automaticity on the effectiveness of a brief weight loss habit-based intervention: secondary analysis of the 10 top tips randomised trial

LiGHT: Erratum to Statistical analysis plan for the Laser-1st versus Drops-1st for Glaucoma and Ocular Hypertension Trial (LiGHT): a multi-centre randomised controlled trial

HomeHealth: Home-based health promotion for older people with mild frailty (HomeHealth): intervention development and feasibility Randomised Controlled Trial

The MARQUE Project: Prevalence of and associations with agitation in people with dementia living in care homes: MARQUE cross-sectional study

ORCID ID: The role of self-regulatory skills and automaticity on the effectiveness of a brief weight loss habit-based intervention: secondary analysis of the 10 top tips randomised trial

TOSCA: Pilot of a randomised controlled trial of the selective serotonin reuptake inhibitor sertraline versus cognitive behavioural therapy for anxiety symptoms in people with generalised anxiety disorder who have failed to respond to low-intensity psychological treatments as defined by the National Institute for Health and Care Excellence guidelines

Methodology: Identifying additional studies for a systematic review of retention strategies in randomised controlled trials: making contact with trials units and trial methodologist

REAL: The Rehabilitation Effectiveness for Activities for Life (REAL) study: a national programme of research into NHS inpatient mental health rehabilitation services across England

2016

MenSS: The Men's Safer Sex project: intervention development and feasibility randomised controlled trial of an interactive digital intervention to increase condom use in men

MenSS: The Men’s Safer Sex Trial: A feasibility randomised controlled trial of an interactive digital intervention to increase condom use in men

ProAct65+: Reducing falls among older people in general practice: The ProAct65+ exercise intervention trial

Medication in Pregnancy: Risks and benefits of psychotropic medication in pregnancy: cohort studies based on UK electronic primary care health records

PRIMROSE: Evaluating the clinical and cost effectiveness of a behaviour change intervention for lowering cardiovascular disease risk for people with severe mental illnesses in primary care (PRIMROSE study): study protocol for a cluster randomised controlled trial

VALID: Community occupational therapy for people with dementia and family carers (COTiD-UK) versus treatment as usual (Valuing Active Life in Dementia [VALID] programme): study protocol for a randomised controlled trial

PRIMROSE: Study protocol for a cluster randomised controlled trial in primary care to lower cardiovascular risk for people with severe mental illnesses (PRIMROSE Study)

The CORE Programme: The CORE Service Improvement Programme for mental health crisis resolution teams: study protocol for a cluster-randomised controlled trial

Medication Review Tool: Results of a pilot cluster randomised controlled trial of the use of a Medication Review Tool for people taking antipsychotic medication 

CIRCLE: A randomised controlled trial of the clinical and cost-effectiveness of a contingency management intervention compared to treatment as usual for reduction of cannabis use and of relapse in early psychosis (CIRCLE): a study protocol for a randomised controlled trial

10 Top Tips: A brief intervention for weight control based on habit-formation theory delivered through primary care: results from a randomised controlled trial

REAL: Recovery-based staff training intervention within mental health rehabilitation units: A realistic evaluation 

predictD-CCRT: Intervention to Prevent Major Depression in Primary Care

REAL: Clinical outcomes and costs for people with complex psychosis; a naturalistic prospective cohort study of mental health rehabilitation service users in England

2015

HeLP-Diabetes: Randomised controlled trial protocol

ProAct65+: Frailty predicts short-term incidence of future falls among British community-dwelling older people: a prospective cohort study nested within a randomised controlled trial

PRIMROSE: Using primary care data to evaluate the 10-year cost-effectiveness of cardiovascular disease risk algorithms in patients with serious mental illness: a patient level simulation

LiGHT: Statistical analysis plan for the Laser-1st versus Drops-1st for Glaucoma and Ocular Hypertension Trial (LiGHT): a multi-centre randomised controlled trial

The Marie Curie Dementia Research Programme: Development of a model for integrated care at the end of life in advanced dementia: a whole systems UK-wide approach

ProAct65+: Promoting physical activity in older people in general practice: ProAct65+ cluster randomised controlled trial

ProAct65+: "Keeping Moving": factors associated with sedentary behaviour among older people recruited to an exercise promotion trial in general practice

MenSS: The Men’s Safer Sex (MenSS) trial: protocol for a pilot randomised controlled trial of an interactive digital intervention to increase condom use in men

PARTNER: The relative clinical and cost-effectiveness of three contrasting approaches to partner notification for curable sexually transmitted infections (STIs): a cluster randomised trial in primary care

HELP: RCT of a Motivational Lifestyle Intervention (the Healthy Eating and Lifestyle Programme (HELP)) Work for Obese Young People

PRIMROSE: Cardiovascular risk prediction models for people with severe mental illness: results from the prediction and management of cardiovascular risk in people with severe mental illnesses (PRIMROSE) research program

EBI-ID: Extended brief intervention to address alcohol misuse in people with mild to moderate intellectual disabilities living in the community (EBI-ID): study protocol for a randomised controlled trial

Can't Forget to Worry: Cognitive Behavioural therapy (CBT) for anxiety in dementia: A pilot randomised controlled trial

Can't Forget to Worry: Factors influencing the Person-Carer Relationship in People with Anxiety and Dementia

PBS: The challenges and successes of managing an RCT examining the effectiveness of postivie behaviour support in routine clinical practice in community intellectual disability services

Methodology: Are multiple primary outcomes analysed appropriately in randomised controlled trials? A review

COPD RCT: Effects of different antibiotic classes on airway bacteria in stable COPD using culture and molecular techniques: A randomised controlled trial

REAL: Cluster randomised controlled trial to assess the clinical effectiveness of a staff training intervention in inpatient mental health rehabilitation units in increasing patients' engagement in activities 

START: Effectiveness of START psychological intervention in reducing abuse by dementia family carers: randomised controlled trial

2014

START: Long-term clinical and cost-effectiveness of psychological intervention for family carers of people with dementia: a single-blind, randomised, controlled trial

START: START (STrAtegies for RelaTives) study: a pragmatic randomised controlled trial to determine the clinical effectiveness and cost-effectiveness of a manual-based coping strategy programme in promoting the mental health of carers of people with dementia

ProAct65+: Multicentre cluster randomised trial comparing a community group exercise programme and home-based exercise with usual care for people aged 65 years and over in primary care

SHEAR: The clinical and cost effectiveness of brief intervention for excessive alcohol consumption among people attending sexual health clinics: a randomised controlled trial

SHEAR: The clinical and cost-effectiveness of brief advice for excessive alcohol consumption among people attending sexual health clinics: a randomised controlled trial

Agitation in Dementia: A systematic review of the clinical effectiveness and cost-effectiveness of sensory, psychological and behavioural interventions for managing agitation in older adults with dementia

POSITIVE: A pilot randomised controlled trial of Problem‐Solving Treatment for Visual Impairment (POSITIVE): protocol paper

PBS: Clinical and cost effectiveness of staff training in Positive Behaviour Support (PBS) for treating challenging behaviour in adults with intellectual disability: A cluster randomised controlled trial

Systematic Review: Non-pharmacological interventions for agitation in dementia: systematic review of randomised controlled trials

Methodology: Community-based recruitment of patients with COPD into clinical research

Methodology: Trials of autologous bone marrow stem cells for heart disease

ESCAPE: Cost-Effectiveness of Computer-Tailored Smoking Cessation Advice in Primary Care: A Randomized Trial (ESCAPE)

Methodology: Use of strategies to improve retention in primary care randomised trials: a qualitative study with in-depth interviews

2013

Shape Up-LD: Piloting a manualised weight management programme (Shape Up-LD) for overweight and obese persons with mild-moderate learning disabilities: study protocol for a pilot randomised controlled trial

The Sexunzipped Trial: Optimizing the Design of Online Randomized Controlled Trials

Methodology: Strategies to improve retention in randomised trials

MATISSE: Estimating effect of intervention delivery in the evaluation of complex intervention with various levels of compliance

Methodology: Strategies to improve retention in randomised trials: a Cochrane systematic review and meta-analysis

REAL: Study protocol: cluster randomised controlled trial to assess the clinical and cost effectiveness of a staff training intervention in inpatient mental health rehabilitation units in increasing service users' engagement in activities

predictD-CCRT: Preventing the onset of major depression based on the level and profile of risk of primary care attendees: protocol of a cluster randomised trial (the predictD-CCRT study)

REAL: Service quality and clinical outcomes: an example from mental health rehabilitation services in England

Escape: A randomised controlled trial of computertailored smoking cessation advice in primary care

START: Clinical effectiveness of a manual based coping strategy programme (START, STrAtegies for RelaTives) in promoting the mental health of carers of family members with dementia: pragmatic randomised controlled trial

2012

The Marie Curie Dementia Research Programme: CoMPASs: IOn programme (Care of Memory Problems in Advanced Stages of dementia: Improving Our Knowledge): protocol for a mixed methods study

Start2Quit: Evaluating the effectiveness of using personal tailored risk information and taster sessions to increase the uptake of smoking cessation services: study protocol for a randomised controlled trial

The Marie Curie Dementia Research Programme: The ToT study: helping with Touch or Talk (ToT): a pilot randomised controlled trial to examine the clinical effectiveness of aromatherapy massage versus cognitive behaviour therapy for emotional distress in patients in cancer/palliative care

ProAct65+: Completion and return of fall diaries varies with participants' level of education, first language, and baseline fall risk

10 Top Tips: Study protocol for the 10 Top Tips (10TT) Trial: Randomised controlled trial of habit-based advice for weight control in general practice

SHEAR: Brief intervention for alcohol misuse in people attending sexual health clinics: study protocol for a randomized controlled trial

Escape: Characteristics of a population-wide sample of smokers recruited proactively for the ESCAPE trial

MATISSE: Group art therapy as an adjunctive treatment for people with schizophrenia: multicentre pragmatic randomised trial

PREDICT-NL: Does recognition of depression in primary care affect outcome? The PREDICT-NL study

Escape: Factors predicting recruitment to a UK wide primary care smoking cessation study (the ESCAPE trial)

2011

HELP: Assessing the efficacy of the Healthy Eating and Lifestyle Programme (HELP) compared with enhanced standard care of the obese adolescent in the community: study protocol for a randomized controlled trial

2010

ProAct65+: Multi-centre cluster randomised trial comparing a community group exercise programme with home based exercise with usual care for people aged 65 and over in primary care: protocol of the ProAct 65+ trial

MATISSE: The MATISSE study: a randomised trial of group art therapy for people with schizophrenia