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STR Operational Research

The Modified Short Treatment Regimen (mSTR) Operational Research Project is a multicountry, prospective, single-arm cohort study that evaluated the effectiveness and safety of mSTRs for fluoroquinolone-susceptible, rifampicin-resistant pulmonary tuberculosis across 13 countries in the WHO European region from 2020 to 2023.

Currently, the TB-IPD contains data from Armenia, Azerbaijan, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Latvia, Moldova, Turkmenistan, and Ukraine.

Korotych O, Achar J, Gurbanova E, Hovhannesyan A, Lomtadze N, Ciobanu A, Skrahina A, Dravniece G, Kuksa L, Rich M, Khachatryan N. Effectiveness and safety of modified fully oral 9-month treatment regimens for rifampicin-resistant tuberculosis: a prospective cohort study. The Lancet Infectious Diseases. 2024 Oct 1;24(10):1151-61.