SEPAC
Screening and early detection to prevent anal cancer; development of a biomarker screening tool.
Project Summary
SEPAC is an anal pre-cancer screening study.
As a part of the SEPAC study, 5 HIV clinics across London provide an opportunity for anyone living with HIV, aged 40 years or older and men who have sex with men or transgender women (male at birth) to be screened for anal pre-cancer. All participants will undergo high resolution anoscopy examination and have samples taken for biomarker analyses.
To learn more about the SEPAC study, please see the attached Participant Information Sheet. You can also contact Research Nurse Deirdre Sally (cnwl.sepac@nhs.net) for further information about the SEPAC study.
The study aims to develop and evaluate a primary screening tool for anal pre-cancer that would allow the identification and treatment of early disease, to help detect anal pre-cancer earlier and improve anal cancer outcomes.
Key Project Information
Dates: March 2020 to September 2024
Status: Current
Principal Investigator: Prof Richard Gilson
Partners:
- Wolfson Institute of Preventive Medicine, Queen Mary, University of London
- Bioscience Technology Facility, University of York
- Central and North West London NHS Foundation Trust
- Homerton University Hospital NHS Foundation Trust / Homerton Anogenital Neoplasia Service (HANS)
- Chelsea and Westminster Hospital NHS Foundation Trust
- Imperial College Healthcare NHS Trust
- Barts Health NHS Trust
Location: UK
Funding: Cancer Research UK
Contact:
- Central and North West London NHS Foundation Trust, Mortimer Market Centre, Research Nurse Deirdre Sally (cnwl.sepac@nhs.net)
- Homerton University Hospital NHS Foundation Trust, Homerton Anogenital Neoplasia Service, Research Nurse Monica James (huh-tr.sepacstudy@nhs.net)
- Chelsea and Westminster Hospital NHS Foundation Trust, 56 Dean Street and 10 Hammersmith Broadway, Senior Research Assistant Veronica Beatriz (chelwest.sepac@nhs.net)
- Imperial College Healthcare NHS Trust, St Mary’s Hospital, Research Nurse Ian McGuinness (ian.mcguinness@nhs.net)
- Barts Health NHS Trust, Royal London Hospital, Dr Jake Bayley (jake.bayley1@nhs.net)
Professor Richard Gilson, Chief Investigator, UCL
Dr Emmi Suonpera, Clinical Project Manager, UCL
Ms Tamzin Cuming, Co-investigator, Homerton University Hospital NHS Foundation Trust
Dr Belinda Nedjai, Co-investigator, Queen Mary, University of London
Professor Andrew Copas, Co-investigator, UCL
Professor Charles Lacey, Co-investigator, University of York
Professor Attila Lorincz, Co-investigator, Queen Mary, University of London
