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Rachel Sagar

Project title

In utero stem cell treatment for babies with osteogenesis imperfecta

Project description

Step 1- Optimising the isolation, expansion and differentiation of human fetal osteoblasts. Optimising the Quasi vivo system and growth of osteoblasts within to form an ‘ex vivo’ bone model.

Step 2- Comparing amniotic fluid stem cells, their conditioned medium and their extracellular vesicles for their effect on bone in the above model.

Start date

03/2017

Primary supervisor

Dr Pascale Guillot

Based at

Great Ormond Street Institute of Child Health

Links

ORCID
Research Gate