Paediatric Neuropathology Group

Our aim is to understand the cellular mechanisms that underlie childhood brain diseases and improve diagnosis for children. We focus on brain tumours and epilepsy.

Biography

I am the Professor of Paediatric Neuropathology at the UCL Great Ormond Street Institute of Child Health and Clinical Lead/Laboratory Director for the department of histopathology at Great Ormond Street Hospital for Children. I run a research programme focussed on paediatric brain tumours and epilepsy. I provide a diagnostic service in paediatric neuropathology. I am Editor in Chief of Neuropathology and Applied Neurobiology and the national lead for the Childhood Solid Tumour domain of the Genomics England Clinical Interpretation Partnership. I was an editor of the WHO classification of childhood tumours (5th edition), and I am a member of the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy (cIMPACT-NOW).

Research

The aim of our group is to understand the development of paediatric brain diseases and in particular to improve diagnosis. We focus on brain tumours and epilepsy.

Conditions: Astrocytoma, Brain tumours in children, Focal Cortical Dysplasia, Epilepsy
Neurogenesis,Neuropathology, Progenitors, Stem cells, Temporal lobes
Methods: Cell culture, Confocal microscopy, Gene expression profiling - tissue level, Histology, Immunohistochemistry, light microscopic techniques, Time-lapse imaging, Stereological analysis

UCL Appointments

Professor of Paediatric Neuropathology
University College London, Developmental Biology & Cancer Dept

Degrees

Fellow of the Royal College of Pathologists
Royal College of Pathologists, UK, 2008
Member of the Royal College of Pathologists
Royal College of Pathologists, UK, 2007
Member of the Royal College of Physicians
Royal College of Physicians, 2000
Doctor of Philosophy
University of Cambridge, 1998
Bachelor of Medicine, Bachelor of Surgery
University of Cambridge, 1997
Master of Arts
University of Cambridge, 1996
Bachelor of Arts
University of Cambridge, 1992