Paediatric Datasets

Author

Overall

Becerra2016

Hicks2014

Lopez_varela_2020

MDRPK2_2022

Migliori_2020_Cfz_Brazil_v2

Ozere2020

Seddon2012

Seddon2014

N observations

939

232

82

136

77

140

53

88

131

Age, median

6.9%

11.0%

8.6%

3.3%

4.0%

18.0%

4.4%

3.8%

2.8%

Sex, male

45.9%

45.7%

43.9%

50.0%

48.1%

47.1%

39.6%

39.8%

47.3%

disease site

82.9%

82.9%

82.9%

82.9%

82.9%

82.9%

82.9%

82.9%

82.9%

AFB positive

27.1%

50.0%

-

13.2%

-

85.7%

-

-

-

Outcome: cured

37.1%

31.9%

61.0%

17.6%

40.3%

40.0%

17.0%

84.1%

22.9%

Outcome: treatment complete

33.4%

38.4%

19.5%

2.9%

5.2%

32.1%

81.1%

15.9%

75.6%

Outcome: lost to follow-up

6.2%

12.5%

6.1%

5.1%

-

10.7%

1.9%

-

0.8%

Outcome: treatment failed

1.8%

4.3%

4.9%

-

-

2.1%

-

-

-

Outcome: death

17.4%

9.1%

-

74.3%

53.2%

-

-

-

-

Lzd resistant at baseline

-

-

-

-

-

-

-

-

-

Mfx resistant at baseline

0.1%

-

-

-

-

0.7%

-

-

-

Lfx resistant at baseline

-

-

-

-

-

-

-

-

-

Ofx resistant at baseline

14.8%

-

-

5.9%

10.4%

2.1%

9.4%

90.9%

26.7%

Cfx resistant at baseline

0.3%

1.3%

-

-

-

-

-

-

-

Bdq resistant at baseline

-

-

-

-

-

-

-

-

-