Kidney Development & Disease Research Group
Overview
Welcome to the home page of the Kidney Development & Disease research group at Great Ormond Street Institute of Child Health.
Our mission is to understand the causes of kidney disease in children and adults. Currently, there are over 65,000 individuals in the UK with end-stage kidney disease, of which 1,000 are children. There is no cure for kidney disease and the ultimate aim of our work is to develop new therapies to treat kidney patients. To do this, we use a combination of experimental models and patient samples alongside state-of-the-art technologies including three-dimensional imaging, gene therapy and stem cell approaches.
Our group consists of a mix of basic scientists and clinicians working together and is led by several principal investigators (Professor David Long, Dr Aoife Waters and Prof Rukshana Shroff). We have strong links with Great Ormond Street Hospital with several investigators holding clinical appointments. We also collaborate closely with the Department of Renal Medicine at the Royal Free Hospital.
Research
Our main research interests are:
1) Understanding normal and abnormal kidney development
2) The kidney filtration barrier in health and in disease
3) Blood vessels and the kidney
4) Translational research
Kidney Development and Disease Research Group
Professor David Long
Prof. David Long's UCL Profile page
Prof. Rukshana Shroff
Prof. Rukshana Shroff's UCL Profile page
Highlight
Latest news:
Our latest article is now in press:
Tissue clearing and deep imaging of the kidney using confocal and two-photon microscopy