Research Projects
An A-Z list of the Research Projects within IGH
- AMBER: A Phase 3, randomized, active-controlled, double-blind study to evaluate efficacy and safety of darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) once daily fixed dose combination regimen versus a regimen consisting of darunavir/cobicistat fixed dose combination coadministered with emtricitabine/tenofovir disoproxil fumarate fixed dose combination in antiretroviral treatment-naïve human immunodeficiency virus type 1 infected subjects. (TMC114FD2HTX3001)
- Analysing immune responses to vaccination
- Barriers, facilitators and preferences for HIV prevention in people experiencing homelessness
- BESTT Women's Study: Bone Evaluation in HIV-positive women who switch from Truvada/NNRTI to Triumeq
- British HIV Association (BHIVA) COVID-19 Registry
- CARE: Diabetes in Ghana
- CASCADE
- China Lancet Countdown Case Study
- Community Survey of the experiences of COVID-19 on people living with HIV in the UK
- COVID-19
- Cultural hierarchies in health
- Disability and Disaster
- DISCOVER: A Phase 3, Randomized, Double-blind Study to Evaluate the Safety and Efficacy of Emtricitabine and Tenofovir Alafenamide (F/TAF) Fixed-Dose Combination Once Daily for Pre-Exposure Prophylaxis in Men and Transgender Women Who Have Sex with Men and Are At Risk of HIV-1 Infection (GS-US-412-2055)
- EMERALD: a randomized, active-controlled, open-label study to evaluate the efficacy and safety of switching to a D/C/F/TAF once-daily single-tablet regimen versus continuing the current regimen consisting of a boosted protease inhibitor (bPI) combined with FTC/TDF
- EuroSIDA: A prospective observational cohort study of HIV-positive individuals in Europe, Israel and Argentina
- EuroSIDA/MISTRAL
- EVE Project: Evidence for Violence prevention in the Extreme
- FLAIR: A Study to Evaluate the Efficacy, Safety, and Tolerability of Long-acting Intramuscular Cabotegravir and Rilpivirine for Maintenance of Virologic Suppression Following Switch From an Integrase Inhibitor in HIV-1 Infected Therapy Naive Participants
- GS-US-380-1489: A Phase 3, Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of GS-9883/Emtricitabine/Tenofovir Alafenamide Versus Abacavir/Dolutegravir/Lamivudine in HIV-1 Infected, Antiretroviral Treatment-Naïve Adults
- GS-US-380-1490: A Phase 3, Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of GS-9883/Emtricitabine/Tenofovir Alafenamide Versus Dolutegravir + Emtricitabine/Tenofovir Alafenamide in HIV-1 Infected, Antiretroviral Treatment-Naïve Adults
- HIPvac: Randomised controlled trial of Imiquimod cream vs. podophyllotoxin in combination with quadrivalent HPV or control vaccination in the treatment and prevention of recurrence of anogenital warts
- HIV BioResource
- HPV Sampling Study
- Icona Network
- The Integrated Sustainable Childhood Pneumonia and Infectious disease Reduction in Nigeria (INSPIRING) programme evaluation and research
- InTune - The UK National Menopause Education and Support Programme
- International SARS-CoV-2 Infection Observational Study (ICOS)
- Many Strong Voices bringing together the peoples of the Arctic and Small Island Developing States to meet the challenges of climate change including health
- Maternal and newborn care practices among disabled women, and their attendance in community groups in rural Makwanpur, Nepal
- MAVMET: A multicentre, 48 week randomised controlled factorial trial of adding maraviroc and/or metformin for hepatic steatosis in HIV-1-infected adults on combination antiretroviral therapy
- mHealth_Injury
- Migration and Xenophobia in Schools (MIXES)
- Mobilising for anxiety and depression in adolescents (MADAD)
- Modelling and cost effectiveness analysis to inform response to high levels of HIV drug resistance in sub-Saharan Africa, including deployment of new drug regimens (HIV Synthesis Model)
- NATSAL: The National Survey of Sexual Attitudes and Lifestyles
- Needs Informed model of Care for people living with HIV (NICHE)
- NICHE
- NIHR HPRU: Health Protection Research Unit in Blood Borne and Sexually Transmitted Infections
- Pantheon 2
- PECAN: Participatory Engagement for City Communities Against NCD Risk in Bangladesh and Nepal
- PERSIMUNE: Centre of excellence for personalised medicine of infectious complications in immune deficiency
- Pharmacokinetics-Pharmacodynamics Group
- The POPPY (Pharmacokinetic and clinical Observations in PeoPle over fiftY) Study
- POPPY Sleep Substudy: study looking at the effects of being HIV positive and being on antiretroviral medication may have on sleeping and sleep pattern
- PrEP IMPACT Trial: A pragmatic health technology assessment of PrEP and implementation
- Race & Health
- RESPOND Africa
- RID-TB: Research to Improve Detection and Treatment of Latent TB Infection
- Royal Free HIV Cohort Study
- Safetxt: A randomised controlled trial of an intervention delivered by mobile phone messaging to reduce sexually transmitted infections (STI) by increasing sexual health precaution behaviours in young people
- SEPAC: Screening and early detection to prevent anal cancer; development of a biomarker screening tool
- SEQUENCE digital - Sexual health equity through evidence-based online clinical care (Improving sexual health for all, in a digital NHS)
- Sixhumene: Using social networks to understand and intervene on HIV epidemic spread
- STI Prophylaxis and Emergence of Antimicrobial Resistance
- STOP HCV-1: Stratified Treatment OPtimisation for HCV-1: An open-label randomised controlled trial (RCT) testing biomarker-stratified short-course first-line and re-treatment direct-acting antiviral (DAA) oral treatment regimens to cure mild chronic Hepatitis C (HCV) disease
- T-pal-Omics Study: Syphilis Transcriptomics: Proof of concept study that aims to utilise next generation sequencing and transcriptomic approaches to understand infection with Treponema pallidum
- TANGO: A Phase III, randomized, multicenter, parallel-group, non-inferiority study evaluating the efficacy, safety, and tolerability of switching to dolutegravir plus lamivudine in HIV-1-infected adults who are virologically suppressed
- TB:HIV - Tuberculosis among HIV-positive Patients: An International Prospective Observational Cohort Study
- TB-IPD Platform
- Testing a community based intervention to reduce neonatal deaths in rural Ghana: Newborn Home Intervention Study (Newhints)
- The Ties That Bind
- Verbal Autopsy through the use of Mobile Phones: What is the acceptability and feasibility of giving cause of death information generated by Mobile InterVA to families of the deceased in rural Nepal?
- VITA: A randomised controlled trial to assess the clinical and cost effectiveness of topical lactic acid gel for treating second and subsequent episodes of bacterial vaginosis