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RESPECT-21

Reorganising specialist cancer surgery for the 21st century: a mixed methods evaluation

Breadcrumb trail

  • Behavioural Science and Health
  • Research
  • The Health Care Organisation and Management Group

Faculty menu

  • CONCORD: CoOrdiNated Care of Rare Diseases (HCOMG)
  • DECIDE: DEcisions in health Care to Introduce or Diffuse innovations using Evidence
  • EMBEDDED:Optimising the impact of health services research on the organisation & delivery of health
  • FLU: Evaluating the implementation of vaccinating school-aged children against seasonal influenza
  • HeLPA: Healthcare leadership with political astuteness
  • IMP2ART: IMPlementing IMProved Asthma self-management as RouTine
  • METRO24/7: Mixed methods analysis of the London Hyperacute Stroke System:
  • Mixed Methods evaluation of a hospital group model using an embedded research approach
  • Mobilising evidence on stroke service organisation
  • Quaser Project
  • Current page: RESPECT-21
  • RSET: The Rapid Service Evaluation Team
  • Safety Netting and Re-consultation for lung cancer symptoms: GP and patient perspectives
  • Stroke: Innovations in major system reconfiguration in England:
  • Using qualitative methods to understand the patient/GP Conversation
  • iQUASER: Implementation & evaluation of a guide for NHS boards to develop quality improvement
  • HERCULES - Healthcare Exemplar For Recovery From COVID-19 By Use Of Linear Examination Systems
  • PHOTONIC: PreHOspital Triage for potential stroke patients

Respect-21 logo

Study overviewA research team, led by Professor Naomi Fulop (UCL Department of Applied Health Research), has been awarded £1.2 million by the National Institute for Health Research Health Services and Delivery Research Programme to study the centralisation of specialist cancer surgical services.

Focus: the study, which started in September 2015, focuses on centralisation of specialist surgical pathways for four cancers across two health care systems: London Cancer (a network of providers across North Central and North East London, and West Essex; population 3.2m) and Greater Manchester Cancer (covering Greater Manchester and East Cheshire; population 3.1m).

The team: The research team is formed of clinicians, patients, and academics from London and Greater Manchester (see study team).

Approach: the research (see study protocol) combines quantitative and qualitative methods to analyse how the centralisations were planned and implemented, and the impact of the changes on organisation and delivery of care, clinical outcomes, patient experience, and cost-effectiveness. The study also analyses patient, professional, and public preferences for changes of this kind (see our at a glance summary).

Contribution: in doing so, this evaluation addresses a number of important gaps in the evidence on centralising specialist cancer surgery, addressing key priorities highlighted in the Five Year Forward View. In addition, it builds on methods developed by the team in conducting high impact research on other forms of major system change.

Details

  • Funder: National Institute for Health Research Health Services and Delivery Research Programme (see NIHR project page)
  • Amount: £1,281,913
  • Duration: September 2015 – August 2019 
  • Key Contacts: Angus Ramsay and Pei Li Ng (London), Catherine Perry (Manchester) 

Study team

  • Chief Investigator: Professor Naomi Fulop (UCL)
  • Co-investigators: Professor Steve Morris, Professor Kathy Pritchard-Jones, Professor Ruth Boaden, Dr Angus Ramsay, Ms Rachael Hunter, Mr John Hines and Mr David Shackley
  • Patient collaborators: Veronica Brinton, Patrick Fahy and John Sandell  
  • Clinical/organisational collaborators: Mr Ravi Barod, Professor Mark Emberton, James Leighton, Claire Levermore, Mr Satish Maddineni, Ms Caroline Moore, Professor Muntzer Mughal, Mr Dipankar Mukherjee, Mr David Shackley, Ms Maxine Tran and Mr Jonathan Vicker
  • Researchers: Dr Caroline Clarke, Dr Mariya Melnychuk, Dr Catherine Perry, Dr Cecilia Vindrola, Dr Victoria Wood and Dr Georgia Black

Publications (all free to download)

Full study report:

  • Fulop NJ et al. Centralisation of specialist cancer surgery services in two areas of England: the RESPECT-21 mixed-methods evaluation. Health and Social Care Delivery Research 2023; 11(2).

Study protocol:

  • Fulop NJ et al. Reorganising specialist cancer surgery for the twenty-first century: a mixed methods evaluations (RESPECT-21). Implementation Science 2016; 11:155.

Research findings:

  • Clarke C S et al. Cost-Utility Analysis of Major System Change in Specialist Cancer Surgery in London, England, Using Linked Patient-Level Electronic Health Records and Difference-in-Differences Analysis. Applied Health Economics and Health Policy 2022; 20 
  • Black G B et al. Loss associated with subtractive health service change: The case of specialist cancer centralization in England. Journal of Health Services Research & Policy 2022; 27:4
  • Vindrola-Padros C et al. Inter-organisational collaboration enabling care delivery in a specialist cancer surgery provider network: A qualitative study. Journal of Health Services Research & Policy 2022; 27:3
  • Melnychuk M et al. Centralising specialist cancer surgery services in England: survey of factors that matter to patients and carers and health professionals. BMC Cancer 2018; 18:226.
  • Vallejo-Torres L et al. Discrete-choice experiment to analyse preferences for centralizing specialist cancer surgery services. British Journal of Surgery 2018; 105:587.
  • Vindrola-Padros C et al. Implementing major system change in specialist cancer surgery: The role of provider networks. Journal of Health Services Research & Policy (2020); 0(0):1-8.
  • Clarke C et al. How to Cost the Implementation of Major System Change for Economic Evaluations: Case Study Using Reconfigurations of Specialist Cancer Surgery in Part of London, England. Applied Health Economics and Health Policy (2021), https://doi.org/10.1007/s40258-021-00660-6.

At a glance summary:

  • Discrete Choice Experiment Findings
  • What is the role of provider networks in implementing major system change in specialist cancer surgery?
  • File
    2021_05_26_respect-21_-_impl_cost_paper_at_a_glance.pdf

  • File
    respect-21_-_at_a_glance_-_value_for_money_of_large_scale_changes.pdf

Newsletters

  • 2020: January; July
  • 2019: February; June; September
  • 2018: March; June; October
  • 2017: January; May; September; December
  • 2016: March; July
  • 2015: December

Further information

NIHR HS&DR project page

Key Contacts:

  • Angus Ramsay and Pei Li Ng (London)
  • Catherine Perry (Manchester)

News item:

  • Clarke, C. (2020). How to cost the implementation of major system change: case study using reconfigurations of specialist cancer surgery in part of London, UK. Health Services Research UK Conference 2020, 26 June 2020.
  • Wise J. (2015). Research team to look at the effect of major reorganisation of cancer surgery. BMJ 2015; 351:h3820 

Remembering our colleague Neil Cameron

Sadly one of our patient collaborator colleagues, Mr Neil Cameron, died on 15 May 2017. Neil contributed a great deal to the study, from the development of the proposal, in particular providing essential feedback on our research questions in relation to patient experience, through to the work of the study to date. We will continue to acknowledge Neil’s contribution to our study in any outputs that we make.

LATEST PUBLICATIONS:

February 2023

Full report: Centralisation of specialist cancer surgery services in two areas of England: the RESPECT-21 mixed-methods evaluation. by Fulop NJ et al.  

July 2022

Cost-Utility Analysis of Major System Change in Specialist Cancer Surgery in London, England. by Clarke CS et al. 

April 2022

Loss associated with subtractive health service change: The case of specialist cancer centralization in England. by Black GB et al. 

PAST EVENT:

20 April 2021, 2-4pm

Link

Workshop: Building lessons for service change - the case of centralising specialist cancer surgery.

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