Lead: Prof Juan Pablo Kaski
Group members: Dr Shahin Moledina, Dr Gabrielle Norrish, Dr Olga Boleti, Dr Sara Moscatelli, Jennifer Tollit, Catherine Renwick, Dr Zhia Lim, Dr Elena Cervi, Dr Luke Starling, Dr Sadia Quyam, Ella Field, Lynsay MacDonald, Sophie Arbos, Annabelle Barnes, Imogen Heenan, Leonie Luedke, Dorothy Mortley, Joanna Jager
The UCL Centre for Paediatric Inherited and Rare Cardiovascular Disease is a multidisciplinary clinical and translational research group focussed on understanding disease mechanisms and investigating novel therapeutic approaches for genetic and rare cardiovascular disorders in childhood. The Centre is based in the Zayed Centre for Research into Rare Diseases in Children and has close links with the internationally recognised clinical UK National Paediatric Pulmonary Hypertension service and the Centre for Inherited Cardiovascular Diseases at Great Ormond Street Hospital.
The Centre’s research portfolio is underpinned by advanced phenotyping, multi-omic characterisation and clinical outcomes and data linkage research methodologies, with the aim of developing personalised therapeutic strategies. Research is supported by grants and fellowships from the Medical Research Council (MRC), British Heart Foundation (BHF), Action Medical Research (AMR), National Institute of Health Research (NIHR), Great Ormond Street Hospital Children’s Charity (GOSHCC), the Dinosaur Trust, Max’s Foundation and the GOSH and UCL Biomedical Research Centres.
The Centre hosts the International Paediatric Hypertrophic Cardiomyopathy Consortium (IPHCC), responsible for the development of the HCM Risk-Kids sudden death risk prediction model.
