Institute for the Physics of Living Systems


IPLS Seminar - Professor Ray Goldstein

16 March 2016, 11:00 am–12:00 pm

Event Information

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MRC Building, LMCB Seminar Room (2nd Floor)

Title: Upside down and inside out: the biomechanics of cell sheet folding

Abstract: Deformations of cell sheets are ubiquitous in early animal development, 

often arising from a complex and poorly understood interplay of cell 

shape changes, division, and migration. In this talk I will describe an 

approach to understanding such problems based on perhaps the simplest 

example of cell sheet folding: the "inversion" process of the algal 

genus Volvox, during which spherical embryos literally turn themselves 

inside out through a process hypothesized to arise from cell shape 

changes alone.  Through a combination of light sheet microscopy and 

elasticity theory a quantitative understanding of this process is now 


Host: Dr Melda Tozluoglu (m.tozluoglu@ucl.ac.uk)