IPLS Seminar - Prof Dagmar Iber (ETH Zurich)

Title: From Networks to Function - Computational Models of Organogenesis

Abstract: One of the major challenges in biology concerns the integration of data across length and time scales into a consistent framework: how do macroscopic properties and functionalities arise from the molecular regulatory networks ­and how do they evolve? Morphogenesis provides an excellent model system to study how simple molecular networks robustly control complex pattern forming processes on the macroscopic scale in spite of molecular noise, and how important functional variants can evolve from small genetic changes. Recent advances in 3D imaging technologies, computer algorithms, and computer power now allow us to develop and analyse increasingly realistic models of biological control. In my talk, I will show how data-based modelling can be used to define mechanisms for fundamental developmental processes such as the control of branching processes and the scaling of developmental pattern on differently sized embryonic domains.

Host: Prof Andrew Oates (andrew.oates@crick.ac.uk)

• If you would like to meet with Professor Iber during her visit, please contact Andy.
• Students and Postdocs have the opportunity to have lunch with Professor Iber. If you would like to do so, please contact An Tyrrell (a.tyrrell@ucl.ac.uk)