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Contact
- f.kozielski@ucl.ac.uk
- Address
-
University College London
UCL School of Pharmacy
29-39 Brunswick Square
London
WC1N 1AX
Selected Research
Structural insights into a unique inhibitor binding pocket in kinesin spindle protein. (2013). Ulaganathan V., Talapatra S.K., Rath O., Pannifer A., Hackney D.D., Kozielski F. J. Am. Chem. Soc.135, 2263-2272.
The structure of the kinesin-1 motor-tail complex reveals the mechanism of autoinhibition. (2011). Kaan H.Y., Hackney D.D., Kozielski F. Science. 333, 883-885.
Optimized S-trityl-L-cysteine-based inhibitors of kinesin spindle protein with potent in vivo antitumor activity in lung cancer xenograft models. (2013). Good J.A., Wang F., Rath O., Kaan H.Y., Talapatra S.K., Podgórski D., MacKay S.P., Kozielski F. J. Med. Chem. 56, 1878-1893.