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UCL School of Pharmacy

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Professor Steve Brocchini

Professor of Chemical Pharmaceutics

Tel: 020 7753 5802
ucnvsbr@ucl.ac.uk

Responsibilities

  • Course coordinator: PHAY3103 and PHAYG065
  • Undergraduate Programme Committee member
  • Co-Director of the UCL-University of Nottingham Centre for Doctoral Training in Advanced Therapeutics and Nanomedicines
  • Faculty member in the NIHR Biomedical Research Centre Moorfields Eye Hospital and UCL Institute of Ophthalmology

Research interests

  • Translational research
  • Formulation sciences
  • Chemical conjugation and protein modification
  • Biomedical polymer sciences

Teaching interests

  • Course design and module coordinator
  • Formulation sciences, pharmaceutical biotechnology, protein modification, polymer/chemical sciences, complex formulations, drug delivery devices
  • Research project supervisor: Postgrad, undergrad and visiting project students

Education

  • BA Chemistry, Reed College, Portland Oregon, USA, 1984
  • PhD Chemistry, University of Michigan, USA, 1989

Prof Steve Brocchini

Appointments

  • Professor
    Pharmaceutics
    UCL School of Pharmacy

Joined UCL

1997-10-01

Our research is multi-disciplined, collaborative and clinically driven.  All projects are hypothesis driven and most projects have a stated clinical translational goal. PhD students typically work on a project that is jointly supervised with a collaborator from another area of science. Most students will work in at least two laboratory environments. Projects tend to address three key themes: (i) to optimise pharmacokinetics, (ii) to ensure a conjugate, dosage form or device is stable and (iii) to conduct research that is scalable so there is a plausible pathway for clinical translation.


During the last decade, projects have covered solid dispersions, pulmonary dry powders, particle coating, polymer-drug conjugates and development of degradable biomaterials. More recent research has focused on protein-PEGylation, development of polyvalent medicines, development of soluble polymer-drug complexes and ocular delivery. Current projects are focused in areas that include (i) chemical-recombinant approaches to develop multifunctional therapeutic proteins, (ii) formulation of protein therapeutics into novel dosage forms, (iii) development of computational pharmaceutics and (iv) new strategies in ocular drug delivery.

Steve has a BA (Reed College, Portland, OR, USA) and a PhD (University of Michigan, Ann Arbor, MI, USA) in chemistry. After a postdoctoral (Emory University, Atlanta, GA, USA) he came to the UK to work as a medicinal chemist (Xenova Ltd, Slough).  Steve then worked as an adjunct faculty member (Rutgers University, Piscataway, NJ, USA) in polymer chemistry and tissue engineering.  Steve joined the UCL School of Pharmacy in late 1997.