Pressurised gyration to produce nanofibrous pharmaceutical materials
1 May 2014
Prof Duncan Craig, in collaboration with Prof Mohan Edirisinghe (PI, UCL Department of Mechanical Engineering) and two named postdoctoral assistants, Dr Bahijja Raimi-Abraham and Dr Suntharavathanan Mahalingam, have secured an EPSRC grant for £418,951 to develop pressurised gyration as a novel means of producing nanofibrous pharmaceutical materials.
This is an innovative new technique, developed by Professor Edirisinghe, which allows rapid production of drug or active-loaded nanofibres in kilogram quantities, thereby rendering the use of such materials commercially feasible.
They plan to demonstrate and explore the utility of the approach using three application areas; polymeric fibres loaded with fine particulates, the formulation of poorly water-soluble drugs for oral administration and as an alternative to freeze drying of proteins. The project is run in collaboration with Astra Zeneca and BASF.
Researchers: Project Leads - Prof Duncan Craig (UCL School of Pharmacy) and Prof Mohan Edirisinghe (UCL Department of Mechanical Engineering).
Collaborators: Dr Bahijja Raimi-Abraham and Dr Suntharavathanan Mahalingam
Contact: Prof Duncan Craig