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UCL Centre for Outcomes Research and Effectiveness

The UCL Centre for Outcomes Research and Effectiveness has a strong commitment to the development, delivery and evaluation of training programmes for psychological interventions.

Research Themes

CORE has a strong commitment to the development, delivery and evaluation of training programmes for psychological interventions and evidence based medicine. The unit also welcomes applications from PhD students.

CORE was established in 1995 to promote effectiveness based research within applied psychology. The initial focus of the unit was on outcomes research led by Dr Paul Clifford. In 2000 Professor Steve Pilling became the Director, and since that time the unit has focused on four main areas:

1. The development of Clinical Guidelines, particularly in mental health

2. The evaluation of complex interventions in Mental Health

3. The evaluation and development of psychological interventions, in particular low intensity interventions

4. Competence frameworks for psychological interventions

CORE Data Lab

Focuses on prognosis and prediction of treatment response for mental disorders uses a range of statistical methods to explore variables associated with prognosis and prediction of treatment response, including systematic reviews, individual patient data sets and large local and national data sets. This has led to a number of important collaborations including the establishment a North Central and East London IAPT data set with NHS colleagues with high-quality individual level data on over 500,000 participants. There are strong links with colleagues at Kings College London and University of Oxford.

The lead role in the analysis of the IAPT national data set (4.5 million participants) which advises NHS-D, Public Health England and NHSE on data analysis and interpretation. This is again in collaboration with University of Oxford. This is the world’s largest data set on psychological therapies and has outcome data on over 90% of those who receive treatment. International  collaborations, particularly with colleagues the United States at the University of Pennsylvania and Vanderbilt University, through the Treatment Ideas Selection Lab (TSIL). This is  an international collaboration focused on improving prediction in the treatment of mental disorders. CORE organised the 2nd Biannual TSIL Conference in London in 2018.

Find out more about TSIL here.

National Collaborating Centre for Mental Health (NCCMH)

The National Collaborating Centre for Mental Health is a collaboration between the Royal College of Psychiatrists and the Centre for Outcomes Research and Effectiveness at University College London. The NCCMH aims to promote the role of evidence synthesis in making informed judgments about healthcare policy. This work has been funded by the WHO, the World Bank, professional bodies  and national governments. It has been led by the NCCMH. The objectives of the programme have been, through appropriate education and training,  to enable  health care systems develop the capacity to develop and  implement  their own guidance. This  work has been undertaken in Italy, Georgia, Turkey, Ukraine, Korea  and the United States. The methodological work currently being undertaken in Ukraine will support the implementation of NICE 2021-2026 strategy through its methodological advances  in guideline development. The guideline development work in collaboration with colleagues at NICE and the National Guideline Alliance  has contributed to significant  methodological developments in the  use of network  meta-analysis  and the  application of health  economic modelling. This has influenced development of guidelines both nationally and  internationally and has resulted in several highly cited papers.

Find out more about the NCCMH here.

Open Dialogue: Development and Evaluation of a Social Network Intervention for Severe Mental Illness (ODDESSI)

ODDESSI is a large-scale programme of research into crisis and continuing mental health care within the NHS. This programme is directed by Professor Steve Pilling (UCL), funded by the National Institute of Health Research (NIHR) and managed by North East London NHS Foundation Trust (NELFT). The study will run from 2017-2022 in five NHS Trust research sites. The development of  methods and support structures to support the implementation of complex mental health interventions in international  health care systems.

Find out more about the ODDESSI trial here.

Key Collaborations

CORE has a number of key collaborations with groups internal and external to UCL. These include: