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National Surveillance of HIV in Pregnancy and Childhood

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Published papers

Papers are listed in descending order according to the year of publication. For inquiries about publications prior to the year 2001, please contact us.

2015-2016

Loss to follow-up after pregnancy among Sub-Suharan African-born women living with Human Immunodeficiency Virus in England, Wales and Northern Ireland. (2016). S Tariq, J Elford, C Chau, C French, M Cortina-Borja, A Brown, V Delpech and P Tookey. Sex Transm Dis.

Pregnancies in older women living with HIV in the UK and Ireland. (2016). CL Townsend, A de Ruiter, H Peters, C Nelson-Piercy, P Tookey and C Thorne. HIV Medicine.

Presentation for care and antenatal management of HIV in the UK, 2009 - 2014. (2016). CE French, C Thorne, L Byrne, M Cortina-Borja and PA Tookey. HIV Medicine

Strategies for Monitoring Outcomes in HIV-Exposed Uninfected Children in the United Kingdom. (2016). Thorne C and Tookey P. Front. Immunol.

Maternal and foetal outcomes among 4118 women with HIV infection treated with lopinavir/ritonavir during pregnancy: analysis of population-based surveillance data from the national study of HIV in pregnancy and childhood in the United Kingdom and Ireland. (2016). Pat A. Tookey, Claire Thorne, Jean van Wyk and Michael Norton. BMC Infect Dis.

The risk of viral rebound in the year after delivery in women remaining on antiretroviral therapy. (2015). Huntington S, Thorne C, Newell ML, Anderson J, Taylor GP, Pillay D, Hill T, Tookey PA, Sabin C, UK CHIC Study and NSHPC. AIDS.

Duration of ruptured membranes and mother-to-child HIV transmission: a prospective population-based surveillance study. (2016). H Peters, L Byrne, A De Ruiter, K Francis, K Harding, GP Taylor, PA Tookey, and CL Townsend. BJOG.

Pregnancy is associated with elevation of liver enzymes in HIV-positive women on antiretroviral therapy. (2015). Huntington S, Thorne C, Newell ML, Anderson J, Taylor GP, Pillay D, Hill T, Tookey PA, Sabin C, UK CHIC Study and NSHPC. AIDS.

2011-2014

Response to antiretroviral therapy (ART): comparing women with previous use of zidovudine monotherapy (ZDVm) in pregnancy with ART naive women. (2014). S Huntington, C Thorne, J Anderson, ML Newell, GP Taylor, D Pillay, T Hill, P Tookey, C Sabin, UK CHIC Study and NSHPC. BMC Infect Dis.

Immunologic status and virologic outcomes in repeat pregnancies to HIV-positive women not on antiretroviral therapy at conception: a case for lifelong antiretroviral therapy? (2014). CE French, C Thorne, S Tariq, M Cortina-Borja and PA Tookey. AIDS.

Earlier initiation of ART and further decline in mother-to-child HIV transmission rates, 2000-2011. (2014). CL Townsend, L Byrne, M Cortina-Borja, C Thorne, A de Ruiter, H Lyall, GP Taylor, CS Peckham and PA Tookey. AIDS. 

Use of combination neonatal prophylaxis for the prevention of mother-to-child transmission of HIV infection in European high-risk infants. (2013). E Chiappini, L Galli, C Giaquinto, L Ene, T Goetghebuer, A Judd, C Lisi, R Malyuta, A Noguera-Julian, JT Ramos, P Rojo-Conejo, C Rudin, P Tookey, M de Martino, C Thorne and European Pregnancy Paediat HIV Coh. AIDS.

Lopinavir dosing in HIV-infected children in the United Kingdom and Ireland. (2013). K. Donegan, K. Doerholt, A. Judd, H. Lyall, E. Menson, K. Butler, P. Tookey, A. Riordan, D. Shingadia, G. Tudor-Williams, D.M. Gibb, A.S. Walker. Pediatr infect dis j.

Influence of short-course antenatal antiretroviral therapy on viral load and mother-to-child transmission in subsequent pregnancies among HIV-infected women. (2013). CE French, PA Tookey, M Cortina-Borja, A de Ruiter, CL Townsend and C Thorne. Antivir ther.

Predictors of pregnancy and changes in pregnancy incidence among HIV-positive women accessing HIV clinical care. (2013). SE Huntington, C Thorne, LK Bansi, J Anderson, ML Newell, GP Taylor, D Pillay, T Hill, PA Tookey and CA Sabin. AIDS.

The prevalence of darunavir-associated mutations in HIV-1-infected children in the UK. (2012). KL Donegan, AS Walker, D Dunn, A Judd, D Pillay, E Menson, H Lyall, G Tudor-Williams and DM Gibb. Antivir ther.

Incidence, patterns, and predictors of repeat pregnancies among HIV-infected women in the United Kingdom and Ireland, 1990-2009. (2012). CE French, M Cortina-Borja, C Thorne, PA Tookey. J acquir immune defic syndr.

Using two on-going HIV studies to obtain clinical data from before, during and after pregnancy for HIV-positive women (2012). SE Huntington, LK Bansi, C Thorne, J Anderson, ML Newell, GP Taylor, D Pillay, T Hill, PA Tookey and CA Sabin. BMC med res methodol.

Pregnancy outcomes in adolescents in the UK and Ireland growing up with HIV. (2012). J. Kenny, B Williams, K Prime, P Tookey and C Foster. HIV med.

The association between ethnicity and late presentation to antenatal care among pregnant women living with HIV in the UK and Ireland. (2012). S Tariq, J Elford, M Cortina-Borja and PA Tookey. AIDS care.

The impact of African ethnicity and migration on pregnancy in women living with HIV in the UK: design and methods. (2012). S Tariq, A Pillen, PA Tookey, AE Brown and J Elford. BMC public health.

Risk of triple-class virological failure in children with HIV: a retrospective cohort study. (2011). H Castro, A Judd, DM Gibb, K Butler, RK Lodwick, A van Sighem, JT Ramos, J Warsawski, C Thorne, A Noguera-Julian, N Obel, D Costagliola, PA Tookey, C Colin, J Kjaer, J Grarup, G Chene and A Phillips. Lancet.

Use of neonatal post-exposure prophylaxis for prevention of mother-to-child HIV transmission in the UK and Ireland, 2001-2008. (2011). H Haile-Selassie, C Townsend and P Tookey. HIV med.

Treatment switches during pregnancy among HIV-positive women on antiretroviral therapy at conception. (2011). SE Huntington, LK Bansi, C Thorne, J Anderson, ML Newell, GP Taylor, D Pillay, T Hill, PA Tookey and CA Sabin. AIDS.

Early antiretroviral therapy in HIV-1-infected infants, 1996-2008: treatment response and duration of first-line regimens. (2011). A Judd, M Penazzato, C Townsend, T Duong, H Castro, T Goetghebuer, J Warszawski, L Galli, E Chiappini, M de Martino, L Ene, C Giaquinto, C Konigs, J LeChenadec, H Lyall, AN Julian, JT Ramos, P Rojo-Conejo, C Rudin, C Thorne, P Tookey, G Tudor-Williams, DM Gibb and EPPICC. AIDS.

Use of zidovudine-sparing HAART in pregnant HIV-infected women in Europe: 2000-2009. (2011). S Tariq, CL Townsend, M Cortina-Borja, T Duong, J Elford, C Thorne and PA Tookey. Journal acquir immune defic syndr.

2008-2010

Antiretroviral therapy in pregnancy: balancing the risk of preterm delivery with prevention of mother-to-child HIV transmission. (2010). CL Townsend, PA Tookey, ML Newell and M Cortina-Borja. Antivir ther.

Antiretroviral therapy and preterm delivery-a pooled analysis of data from the United States and Europe. (2010). C Townsend, J Schulte, C Thorne, KI Dominguez, PA Tookey, M Cortina-Borja, CS Peckham, B Bohannon and ML Newell. BJOG.

Antiretroviral therapy and congenital abnormalities in infants born to HIV-infected women in the UK and Ireland, 1990-2007. (2009). CL Townsend, BA Willey, M Cortina-Borja, CS Peckham and PA Tookey. AIDS.

Tenofovir use in human immunodeficiency virus-1-infected children in the United kingdom and Ireland.(2009). A Riordan, A Judd, K Boyd, D Cliff, K Doerholt, H Lyall, E Menson, K Butler and D Gibb. Pediatr infect dis j.

Vertically acquired HIV diagnosed in adolescence and early adulthood in the United Kingdom and Ireland: findings from national surveillance. (2009). A Judd, R A Ferrand, E Jungmann, C Foster, J Masters, B Rice, H Lyall, PA Tookey and K Prime. HIV med.

In utero exposure to antiretroviral therapy: feasibility of long-term follow-up. (2009). C Hankin, H Lyall, B Willey, C Peckham, J Masters and P Tookey. AIDS care.

Young people in the United Kingdom and Ireland with perinatally acquired HIV: the pediatric legacy for adult services. (2009). C Foster, A Judd, P Tookey, G Tudor-Williams, D Dunn, D Shingadia, K Butler, M Sharland, D Gibb and H Lyall. AIDS patient care STDs.

Trends in management and outcome of pregnancies in HIV-infected women in the UK and Ireland, 1990-2006. (2008). CL Townsend, M Cortina-Borja, CS Peckham, and PA Tookey. BJOG.

Low rates of mother-to-child transmission of HIV following effective pregnancy interventions in the United Kingdom and Ireland, 2000-2006. (2008). CL Townsend, M Cortina-Borja, CS Peckham, A de Ruiter, H Lyall and PA Tookey. AIDS.

Response to combination antiretroviral therapy: variation by age. (2008). CA Sabin, CJ Smith, A d'Arminio Monforte, M Battegay, C Gabiano, L Galli, S Geelen, D Gibb, M Guiguet, A Judd, C Leport, F Dabis, N Pantazis, K Porter, F Raffi, C Thorne, C Torti, S Walker, J Warszawski, U Wintergerst, G Chene and J Lundgren. AIDS.

Differences in factors associated with initial growth, CD4, and viral load responses to ART in HIV-infected children in Kampala, Uganda, and the United Kingdom/Ireland. (2008). A Kekitiinwa, KJ Lee, AS Walker, A Maganda, K Doerholt, SB Kitaka, A Asiimwe, A Judd, P Musoke and DM Gibb. J acquir immune defic syndr.

British HIV Association and Children's HIV Association guidelines for the management of HIV infection in pregnant women 2008. (2008). A de Ruiter, D Mercey, J Anderson, R Chakraborty, P Clayden, G Foster, C Gilling-Smith, D Hawkins, N Low-Beer, H Lyall, S O'Shea, Z Penn, J Short, R Smith, S Sonecha, P Tookey, C Wood and G Taylor. HIV med.

HIV-1 drug resistance in HIV-1-infected children in the United Kingdom from 1998 to 2004. (2008). R Chakraborty, CJ Smith, D Dunn, H Green, T Duong, K Doerholt, A Riordon, H Lyall, P Tookey, K Butler, CA Sabin, D Gibb and D Pillay. Pediatr infect dis j.

2006-2007

Antiretroviral therapy and premature delivery in diagnosed HIV-infected women in the United Kingdom and Ireland. (2007). CL Townsend, M Cortina-Borja, CS Peckham and PA Tookey. AIDS.

Response to Kourtis et al. 'Use of antiretroviral therapy in pregnant HIV-infected women and the risk of premature delivery: a meta-analysis'. (2007). CL Townsend, M Cortina-Borja, CS Peckham and PA Tookey. AIDS.

Pregnancies in young women with vertically acquired HIV infection in Europe. (2007). C Thorne, CL Townsend, CS Peckham, ML Newell and PA Tookey. AIDS.

Testing Times. HIV and other sexually transmitted infections in the UK, 2007,(2007). The UK Collaborative Group for HIV and STI Surveillance, in: Health Protection Agency Centre for Infections, (Ed.), London.

Morbidity, mortality, and response to treatment by children in the United Kingdom and Ireland with perinatally acquired HIV infection during 1996-2006: planning for teenage and adult care. (2007). A Judd, K Doerholt, PA Tookey, M Sharland, A Riordan, E Menson, V Novelli, EG Lyall, J Masters, G Tudor-Williams, T Duong, DM Gibb, Clin Infect Dis.

Long-term follow-up of uninfected children born to HIV-infected women and exposed to antiretroviral therapy: survey of parents' and health professionals' views. (2007). CD Hankin, ML Newell and P Tookey. AIDS care.

Monitoring death and cancer in children born to HIV-infected women in England and Wales: use of HIV surveillance and national routine data. (2007). C Hankin, H Lyall, C Peckham and P Tookey. AIDS.

HIV-1 subtypes in pregnant women in the UK. (2007). M Cortina-Borja, D Williams, WD Cubitt, PA Tookey, ML Newell and CS Peckham. Int J STD AIDS.

Antiretroviral therapy and congenital abnormalities in infants born to HIV-1-infected women in the United Kingdom and Ireland, 1990 to 2003. (2006). CL Townsend, PA Tookey, M Cortina-Borja and CS Peckham. Journal acquir defic syndr.

Uptake of antenatal HIV testing in the United Kingdom: 2000-2003. (2006). CL Townsend, S Cliffe and PA Tookey. J public health (Oxf).

HIV and other sexually transmitted infections in the UK, 2006: A complex picture,(2006). The UK Collaborative Group for HIV and STI Surveillance, in: Health Protection Agency Centre for Infections, (Ed.), London.

Mapping the issues. HIV and other sexually transmitted infections in the United Kingdom: 2005,(2006). The UK Collaborative Group for HIV and STI Surveillance, in: Health Protection Agency Centre for Infections, (Ed.), London.

Predictive value of absolute CD4 cell count for disease progression in untreated HIV-1-infected children. (2006). HIV Paediatric Prognostic Markers Collaborative Study. AIDS.

Underdosing of antiretrovirals in UK and Irish children with HIV as an example of problems in prescribing medicines to children, 1997-2005: cohort study. (2006). EN Menson, AS Walker, M Sharland, C Wells, G Tudor-Williams, FA Riordan, EG Lyall and DM Gibb. BMJ.

Outcomes for human immunodeficiency virus-1-infected infants in the United kingdom and Republic of Ireland in the era of effective antiretroviral therapy. (2006). K Doerholt, T Duong, P Tookey, K Butler, H Lyall, M Sharland, V Novelli, A Riordan, D Dunn, AS Walker and DM Gibb. Pediatr infect dis j.

Monitoring the effectiveness of HIV and STI prevention initiatives in England, Wales, and Northern Ireland: where are we now? (2006). AE Brown, SE Tomkins, LE Logan, DS Lamontagne, HL Munro, VD Hope, A Righarts, JE Blackham, BD Rice, TR Chadborn, PA Tookey, JV Parry, V Delpech, ON Gill and KA Fenton. Sex transm infect.

2001-2005

Use of total lymphocyte count for informing when to start antiretroviral therapy in HIV-infected children: a meta-analysis of longitudinal data. (2005). HIV Paediatric Prognostic Markers Collaborative Study. Lancet.

Response to highly active antiretroviral therapy varies with age: the UK and Ireland Collaborative HIV Paediatric Study. (2004). AS Walker, K Doerholt, M Sharland and DM Gibb. AIDS.

Focus on prevention. HIV and other sexually transmitted infections in the United Kingdom in 2003. (2004). The UK Collaborative Group for HIV and STI Surveillance, in: Health Protection Agency Centre for Infections, (Ed.), London.

Reducing mother-to-child transmission of HIV-1 infection: the role of antiretroviral therapy and caesarean section delivery. (2004). C. Peckham, P. Tookey, M. L. Newell, The Obstetrics and Gynaecology Yearbook, RCOG Press, London, pp. 401-413.

Recent trends in HIV and other STIs in the United Kingdom: data to the end of 2002. (2004). AE Brown, KE Sadler, SE Tomkins, CA McGarrigle, DS LaMontagne, D Goldberg, PA Tookey, B Smyth, D Thomas, G Murphy, JV Parry, BG Evans, ON Gill, F Ncube, KA Fenton. Sex Transm Infect.

HIV prevalence in pregnant women in an ethnically diverse population in the UK: 1998-2002. (2004). M Cortina-Borja, S Cliffe, P Tookey, D Williams, WD Cubitt and C Peckham. AIDS.

Decline in mortality, AIDS, and hospital admissions in perinatally HIV-1 infected children in the United Kingdom and Ireland. (2003). DM Gibb, T Duong, PA Tookey, M Sharland, G Tudor-Williams, V Novelli, K Butler, A Riordan, L Farrelly, J Masters, CS Peckham, DT Dunn. BMJ.

Short-term risk of disease progression in HIV-1-infected children receiving no antiretroviral therapy or zidovudine monotherapy: a meta-analysis. (2003). D Dunn, Lancet 362 1605-1611.

Renewing the focus. HIV and other sexually transmitted infections in the United Kingdom in 2002,(2003). Health Protection Agency, SCIEH, ISD, National Public Health Service for Wales, CDSC Northern Ireland, UASSG, in: Health Protection Agency, (Ed.), London.

Antenatal detection of HIV: national surveillance and unlinked anonymous survey (2001). S Cliffe, PA Tookey and A Nicoll. BMJ.