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Mitogent

We are studying the causes of deafness among children who were born prematurely. 
We know that around 3% of babies born at 32 weeks or less may develop problems with their hearing but it isn’t clear why. 

What?

We want to study some of the factors that may increase this risk – things that happen after very premature birth, some of the medicines which may be used, for example gentamicin, an antibiotic, and changes in the genes.

Why Mitogent?

We think that one gene change in particular called m.1555A>G may make children and adults more susceptible to hearing loss caused by aminoglycoside antibiotics such as gentamicin.  This gene is found inside the cell in the mitochondria. Hence we have called the study Mitogent – mitochondria and gentamicin.

Funding

In this website we explain more about the study, which is generously funded by a grant from Action on Hearing Loss.

Page last modified on 11 apr 13 15:01