Advanced X-Ray Imaging Group (AXIm)

Quantitative phase retrieval with incoherent sources: this was considered a virtually impossible task, but was made possible by Peter Munro’s combined analysis of pairs of phase images acquired with the UCL method (Munro et al PNAS 109(2012) 13922), inspired by Dean Chapman’s pioneering work with crystals (Chapman et al Phys. Med. Biol. 42 (1997) 2015)

Phase-retrieval with polychromatic beams: conventional x-ray sources emit multiple wavelengths at the same time: this means the retrieved phase is necessarily a weighted average over the polychromatic spectrum. We developed a framework to calculate this average, depending on the XPCI method and the sample (Munro and Olivo Phys. Rev. A 87 (2013) 053838)

Dark-field or “ultra-small angle scatter” imaging: rather counter-intuitively, phase-based x-ray methods can enable access to sample features well below the spatial resolution of the imaging system. Marco Endrizzi has developed an acquisition procedure and analysis method that enables this using the UCL XPCI setup (Endrizzi et al. Appl. Phys. Lett. 104 (2014) 024106)

Low-dose phase-enhanced mammography: XPCI allows improved detection of breast cancer, as demonstrated by the in vivo study underway at the Trieste synchrotron, partly based on Olivo’s early research. We have demonstrated that the UCL method allows similar results to be obtained with conventional sources, opening the way to clinical translation (Olivo et al Med. Phys. 40 (2013) 090701, – see also feature on Physics Today)

Phase Tomography: the special features of the UCL XPCI method mean that tomography can be performed quickly and at low dose. Charlotte Hagen demonstrated this first at synchrotrons (Hagen et al Opt. Exp. 22 (2014) 7989), then with our laboratory sources achieving record-low dose delivery (Hagen et al Med. Phys. 41 (2014) 070701, editor’s pick and cover feature).

Phase-enhanced tomosynthesis: tomosynthesis is an emerging modality in various fields – notably breast imaging where the use of conventional CT has limitations. Magdalena Szafraniec demonstrated it can be easily combined with the UCL XPCI method while maintaining dose and exposure time compatible with clinical requirements (Szafraniec et al Phys. Med. Biol. 59 (2014) N1, see also feature on Medical Physics Web) 

Nano-radian sensitivity at synchrotrons: having developed a method that generates strong phase signals with incoherent sources, we asked ourselves the question “what happens if we bring it back to coherent sources”. Paul Diemoz demonstrated it leads to unprecedented phase sensitivity of 2 nrad: the angle subtended by 2 micron at a distance of 1 km (Diemoz et al Phys. Rev. Lett. 110 (2013) 138105)

Single-image retrieval: a key limitation of XPCI methods is that they require more than one image to disentangle phase from attenuation – the latter does not disappear because a system is made sensitive to phase. Inspired by pioneering work by Paganin et al (J. Microsc. 206 (2002) 33), Paul Diemoz developed a single-shot phase retrieval method (Diemoz et al J. Synchrotron Radiat. 22 (2015) 1072)

Beam tracking: the UCL XPCI method uses x-ray masks to achieve sensitivity to phase. Fabio Vittoria demonstrated that, if a detector with sufficient resolution is available, not only can one of these masks be eliminated, but attenuation, phase and dark-field can be acquired in a single shot (Vittoria et al Appl. Phys. Lett. 106 (2015) 224102 and Sci. Rep 5 (2015) 16318)

New imaging agents: many x-ray procedures are based on agents such as iodine, which increase x-ray contrast but can cause severe allergic reactions. Other modalities like ultrasound use harmless agents such as microbubbles, which are invisible to x-rays. Tom Millard proved XPCI methods enables their visualization (Millard et al Appl. Phys. Lett. 103 (2013) 114105 and Sci. Rep 5 (2015) 12509)

Phase imaging with misaligned optical elements: one of the key challenges in the translation of XPCI into real-world environments is to keep optical elements (e.g. x-ray masks) aligned during imaging. Marco Endrizzi developed a methodology that enables achieving high quality, quantitatively correct results also with misaligned masks (Endrizzi et al Appl. Phys. Lett. 107 (2015) 124103)

Phase microscopy at high x-ray energy with laboratory sources: x-ray microscopy is a challenging area which often requires specialized sources and is usually implemented at low x-ray energy. Marco Endrizzi demonstrated that micrometric resolution, plus quantitative phase retrieval, can be achieved at high x-ray energies with standard laboratory equipment (Endrizzi et al Opt. Lett. 39 (2014) 3332).

Refereed Journals Papers

2017

Endrizzi M, Vittoria F A, Rigon L, Dreossi D, Iacoviello F, Shearing P R and Olivo A “X-ray phase-contrast radiography and tomography with a multi-aperture analyser”, Phys. Rev. Lett., in press    

Modregger P, Kagias M, Irvine S C, Bronnimann R, Jefimovs K, Endrizzi M and Olivo A "Interpretation and utility of the moments of small angle x-ray scattering distributions", Phys. Rev. Lett., in press

Astolfo A, Endrizzi M, Vittoria F, Diemoz P, Price B, Haig I and Olivo A “Large field of view, fast and low dose multimodal phase-contrast at high x-ray energy”, Sci. Rep., in press

Zamir A, Diemoz P C, Vittoria F A, Hagen C K, Endrizzi M and Olivo A “Edge illumination x-ray phase tomography of multi-material samples using a single-image phase retrieval algorithm”, Opt. Exp., in press

Hagen C K, Diemoz P C and Olivo A “On the relative performance of edge illumination x-ray phase contrast CT and conventional, attenuation-based CT”. Med. Phys., in press

Diemoz P C, Hagen C K, Endrizzi M, Minuti M, Bellazzini R, Urbani L, De Coppi P and Olivo A “Single-shot x-ray phase-contrast computed tomography with non-microfocal laboratory sources”, Phys. Rev. Appl. 7 (2017) 044029 (also in physics.aps.org as a focus story - see https://physics.aps.org/articles/v10/48)

Vittoria F A, Endrizzi M and Olivo A “Retrieving the signal from ultrasmall-angle x-ray scattering with polychromatic radiation in speckle-tracking and beam-tracking phase contrast imaging”, Phys. Rev. Appl. 7 (2017) 034024

Chen Y, Guan H, Hagen C K, Olivo A and Anastasio M A “Single-shot edge-illumination x-ray phase-contrast tomography enabled by joint image reconstruction, Opt. Lett. 42 (2017) 619-22

2016

Diemoz P C, Bravin A, Sztrokay-Gaul A, Ruat M, Grandl S, Mayr D, Auweter S, Mittone A, Brun E, Ponchut C, Reiser M F, Coan P and Olivo A “A method for high-energy, low-dose mammography using edge-illumination x-ray phase contrast imaging”, Phys. Med. Biol. 61 (2016) 8750-61

Astolfo A, Endrizzi M, Kallon G, Millard T, Vittoria F and Olivo A “A first investigation of accuracy, precision and sensitivity of phase-based x-ray dark field imaging”, J. Phys. D: Appl. Phys. 49 (2016) 485501

Zamir A, Endrizzi M, Hagen CK, Vittoria FA, Urbani L, De Coppi P and Olivo A “Robust phase retrieval for high resolution edge illumination x-ray phase contrast computed tomography in non-ideal environments”, Sci. Rep. 6 (2016) 31197

Diemoz P C, Vittoria F A, Hagen C K, Endrizzi M, Coan P, Bravin A, Wagner U H, Rau C, Robinson I K and Olivo A, “A single-image retrieval method for edge illumination x-ray phase-contrast imaging: application and noise analysis”, Physica Medica 32 (2016) 1759-64

Modregger P, Cremona T P, Benarafa C, Schittny J, Olivo A and Endrizzi M “Small angle x-ray scattering with edge-illumination”, Sci. Rep. 6 (2016) 30940

Basta D, Endrizzi M, Vittoria F A, Astolfo A and Olivo A “Compact and cost effective lab-based edge-illumination x-ray phase contrast imaging with a structured focal spot”, Appl. Phys. Lett. 108 (2016) 224102

Hagen C K, Endrizzi M, Diemoz P C and Olivo A “Reverse projection retrieval in edge illumination x-ray phase contrast computed tomography” J. Phys. D: Appl. Phys. 49 (2016) 255501(included in 2016 highlights)

Maghsoudlou P, Georgiades F, Smith H, Milan A, Shangaris P, Urbani L, Loukogeorgakis S P, Lombardi B, Mazza G, Hagen C, Sebire N J, Turmaine M, Eaton S, Olivo A, Godovac-Zimmermann J, Pinzani M, Gissen P and De Coppi P “Optimisation of liver decellularization maintains extracellular matrix micro-architecture and composition predisposing to effective cell seeding, Plos One 11 (2016) e0155324

Diemoz P C, Vittoria F A and Olivo A “The concept of contrast transfer function for edge illumination X-ray phase-contrast imaging and its comparison with the free-space propagation technique”, Opt. Exp. 24 (2016) 11250-65

Endrizzi M, Astolfo A, Vittoria F A, Millard T P and Olivo A “Asymmetric masks for laboratory-based X-ray phase-contrast imaging with edge illumination”, Sci. Rep. 6 (2016) 25466

Zamir A, Arthurs O, Hagen C K, Diemoz P C, Brochard T, Bravin A, Sebire N and Olivo A “X-ray phase contrast tomography: proof of principle for post-mortem imaging”, Br. J. Radiol. 89 (2016) 20150565

2015

Hagen C K, Maghsoudlou P, Totonelli G, Diemoz P C, Endrizzi M, Rigon L, Menk R H, Arfelli F, Dreossi D, Brun E, Coan P, Bravin A, De Coppi P and Olivo A “High contrast microstructural visualization of natural acellular matrices by means of phase-based x-ray tomography”, Sci. Rep. 5 (2015) 18156

Kallon G K, Wesolowski M, Vittoria F A, Endrizzi M, Basta D, Millard T P, Diemoz P C and Olivo A “A laboratory based edge-illumination x-ray phase-contrast imaging setup with two-directional sensitivity”, Appl. Phys. Lett. 107 (2015) 204105

Vittoria F A, Endrizzi M, Diemoz P C, Zamir A, Wagner U H, Rau C, Robinson I K and Olivo A “X-ray absorption, phase and dark-field tomography through a beam tracking approach”, Sci. Rep 5 (2015) 16318

M. Endrizzi, B. I. S. Murat, P. Fromme and A. Olivo “Edge-illumination x-ray darl-field imaging for visualising defects in composite structures”, Compos. Struct. 134 (2015) 895-9

M. Endrizzi, D. Basta and A. Olivo “Laboratory-based x-ray phase contrast imaging with misaligned optical elements”, Appl. Phys. Lett. 107 (2015) 124103

D. Basta, M. Endrizzi, F. A. Vittoria, G. K. N. Kallon, T. P. M. Millard. P. C. Diemoz and A. Olivo “Note: design and realization of a portable edge illumination c-ray phase contrast imaging system”, Rev. Sci. Instrum. 86 (2015) 096102

Hagen C K, Coan P, Bravin A, Olivo A and Diemoz P C “A continuous sampling scheme for edge illumination x-ray phase contrast imaging”, J. Appl. Phys. 118 (2015) 054901

Millard T P, Endrizzi M, Everdell N, Rigon L, Arfelli F, Menk R H, Stride E and Olivo A “Evaluation of microbubble contrast agents for dynamic imaging with x-ray phase contrast”, Sci. Rep. 5 (2015) 12509

Diemoz P C, Vittoria F A, Hagen C K, Endrizzi M, Coan P, Brun E, Wagner U H, Rau C, Robinson I K, Bravin A and Olivo A “Single-image phase retrieval using an edge illumination X-ray phase contrast imaging setup”, J. Synchrotron Radiat. 22 (2015) 1072-7

Endrizzi M, Vittoria F A, Kallon G, Basta D, Diemoz P C, Vincenzi A, Delogu P, Bellazzini R and Olivo A “An achromatic approach to phase-based multi-modal imaging with conventional X-ray sources”, Opt. Exp. 23 (2015) 16473-80

Vittoria F A, Kallon G K N, Basta D, Diemoz P C, Robinson I K, Olivo A and Endrizzi M “Beam tracking approach for single-shot retrieval of absorption, refraction and dark-field signals with laboratory x-ray sources”, Appl. Phys. Lett. 106 (2015) 224102

Szafraniec M, Konstantinidis A C, Tromba G, Dreossi D, Vecchio S, Rigon L, Sodini N, Naday S, Gunn S, McArthur A and Olivo A “Synchrotron based planar imaging and digital tomosynthesis of breast and biopsy phantoms using a CMOS active pixel sensor”, Phys. Medica 31 (2015) 192-8

2014

Endrizzi M and Olivo A “Absorption, refraction and scattering retrieval with an edge-illumination-based imaging setup”, J. Phys. D: Appl. Phys. 47 (2014) 505102

Diemoz P C and Olivo A “On the origin of contrast in edge illumination x-ray phase contrast imaging”, Opt. Exp. 22 (2014) 28199-28214 (ALSO IN: Virtual Journal for Biomedical Optics 9, Issue 13, 2014)

Hagen C K, Endrizzi M, Diemoz P C and Olivo A “The effect of the spatial sampling rate on quantitative phase information extracted from planar and tomographic edge illumination x-ray phase contrast images”, J. Phys. D: Appl. Phys. 47 (2014) 455401

Uroukov I, Speller R D and Olivo A, “Image enhancement of x-ray phase contrast images of micro objects”, Signal Processing Research 3 (2014) 24-30

Cipiccia S, Vittoria F A, Weikum M, Olivo A and Jaroszynski D A “Inclusion of coherence in Monte Carlo models for simulation of x-ray phase contrast imaging”, Opt. Exp. 22 (2014) 23480-8

Olivo A and Castelli C “X-Ray phase contrast imaging: from synchrotrons to conventional sources”, Riv. Nuovo Cimento 37 (2014) 467-508 (invited review)

Hagen C K, Endrizzi M, Diemoz P C, Munro P R T and Olivo A “Low-dose phase contrast tomography with conventional x-ray sources”, Med. Phys. (letters section) 41 (2014) 070701

Vittoria F A, Diemoz P C, Endrizzi M, De Caro L, Wagner U H, Rau C, Robinson I K and Olivo A “Phase retrieval through a one-dimensional ptychohraphic engine”, Opt. Exp. 22 (2014) 17281-91 (ALSO IN: Virtual Journal for Biomedical Optics 9, Issue 9, 2014)

Diemoz P C, Vittoria F A and Olivo A “Spatial resolution of edge illumination X-ray phase-contrast imaging”, Opt. Exp., 22 (2014) 15514-29

Endrizzi M, Vittoria F A, Diemoz P C, Lorenzo R, Speller R D, Wagner U, Rau C, Robinson I K and Olivo A “Phase-contrast microscopy at high x-ray energy with a laboratory set-up”, Opt. Lett. 39 (2014) 3322-5 (ALSO IN: Virtual Journal for Biomedical Optics 9, Issue 8, 2014)

Millard T P, Endrizzi M, Diemoz P C, Hagen C K and Olivo A “Monte Carlo model of a polychromatic laboratory based edge illumination x-ray phase contrast system”, Rev. Sci. Instrum. 85 (2014) 053702

Vittoria F A, Endrizzi M, Diemoz P C, Wagner U H, Rau C, Robinson I K and Olivo A “Virtual edge illumination and one dimensional beam tracking for absorption, refraction and scattering retrieval”, Appl. Phys. Lett. 104 (2014) 134102

Hagen C K, Diemoz P C, Endrizzi M, Rigon L, Dreossi D, Arfelli F, Lopez F C M, Longo R and Olivo A “Theory and preliminary experimental verification of quantitative edge illumination x-ray phase contrast tomography”, Opt. Exp. 22 (2014) 7989-8000 (ALSO IN: Virtual Journal for Biomedical Optics 9, Issue 6, 2014)

Szafraniec M B, Millard T P, Ignatyev K, Speller R D and Olivo A “Proof-of-concept demonstration of edge-illumination x-ray phase contrast imaging combined with tomosynthesis”, Phys. Med. Biol. 59 (2014) N1-N10

Endrizzi M, Diemoz P C, Millard T P, Jones J L, Speller R D, Robinson I K and Olivo A “Hard x-ray dark-field imaging with incoherent sample illumination”, Appl. Phys. Lett. 104 (2014) 024106

Kavanagh A, Olivo A, Speller R and Vojnovic B “Feasibility testing of a pre-clinical coded aperture phase contrast imaging configuration using a simple fast Monte Carlo simulator” Biomed. Opt. Exp. 5 (2014) 93-105

2013

Diemoz P C, Hagen C K, Endrizzi M and Olivo A “Sensitivity of laboratory based implementations of edge illumination x-ray phase-contrast imaging” Appl. Phys. Lett. 103 (2013) 244104

Konstantinidis A C, Szafraniec M B, Rigon L, Tromba G, Dreossi D, Sodini N, Liaparinos P F, Naday S, Gunn S, McArthur A, Speller R D and Olivo A “X-ray performance evaluation of the Dexela CMOS APS x-ray detector using monochromatic synchrotron radiation in the mammographic range” IEEE Trans. Nucl. Sci. 60 (2013) 3969-80

Vittoria F A, Diemoz P C, Endrizzi M, Rigon L, Lopez F C, Dreossi D, Munro P R T and Olivo A “Strategies for efficient and fast wave optics simulation of coded-aperture and other x-ray phase-contrast imaging methods”, Appl. Opt. 52 (2013) 6940-7

Millard T, Endrizzi M, Rigon L, Arfelli F, Menk R H, Owen J, Stride E and Olivo A “Quantification of microbubble concentration through x-ray phase contrast imaging”, Appl. Phys. Lett. 103 (2013) 114105

Olivo A, Gkoumas S, Endrizzi M, Hagen C K, Szafraniec M B, Diemoz P C, Munro P R T, Ignatyev K, Johnson B, Horrocks J A, Vinnicombe S J, Jones J L and Speller R D “Low-dose phase contrast mammography with conventional x-ray sources”, Med. Phys. (letters section) 40 (2013) 090701

Millard P T, Endrizzi M, Ignatyev K, Hagen C K, Munro P R T, Speller R D and Olivo A “Method for automatization of the alignment of a laboratory based x-ray phase contrast edge illumination system”, Rev. Sci. Instrum. 84 (2013) 083702

Munro P R T and Olivo A “X-ray phase-contrast imaging with polychromatic sources and the concept of effective energy”, Phys. Rev. A 87 (2013) 053838

Munro P R T, Hagen C K, Szafraniec M B and Olivo A “A simplified approach to quantitative coded aperture X-ray phase imaging”, Opt. Exp. 21 (2013) 11187-201

Diemoz P C, Endrizzi M, Zapata C E, Pesic Z D, Rau C, Bravin A, Robinson I K and Olivo A “X-ray phase-contrast imaging with nanoradian resolution”, Phys. Rev. Lett. 110 (2013) 138105

Munro P R T, Rigon L, Ignatyev K, Lopez F C, Dreossi D, Speller R D and Olivo A “A quantitative, non-interferometric x-ray phase contrast imaging technique” Opt. Exp. 21 (2013) 648-61 (ALSO FEATURED IN: Virtual Journal for Biomedical Optics 8, Issue 2, 2013)

2012

Marenzana M, Hagen C K, Das Neves Borges P, Endrizzi M, Szafraniec M B, Ignatyev K and Olivo A “Visualization of small lesions in rat cartilage by means of laboratory-based X-ray phase contrast imaging”, Phys. Med. Biol. 57 (2012) 8173-84

Munro P R T, Ignatyev K, Speller R D and Olivo A “Phase and absorption retrieval using incoherent x-ray sources” PNAS 109 (2012) 13922-7

Konstantinidis A C, Szafraniec M B, Speller R D and Olivo A “The Dexela 2932 CMOS X-ray detector: a flat panel detector based on CMOS active pixel sensors for medical imaging applications”, Nucl. Instr. Meth. A 689 (2012) 12-21

Olivo A, Diemoz P C and Bravin A “Amplification of the phase contrast signal at very high x-ray energies”, Opt. Lett. 37 (2012) 915-17

2011

Ignatyev K, Munro P R T, Chana D, Speller R D and Olivo A “A new generation of x-ray baggage scanners based on a different physical principle” Materials 4 (2011) 1846-60

Ignatyev K, Munro P R T, Speller R D and Olivo A “Effects of signal diffusion on x-ray phase contrast images” Rev. Sci. Instrum. 82 (2011) 073702

Ignatyev K, Munro P R T, Chana D, Speller R D and Olivo A “Coded apertures allow high-energy x-ray phase contrast imaging with laboratory sources” J. Appl. Phys. 110 (2011) 014906

Olivo A, Ignatyev I, Munro P R T and Speller R D “Noninterferometric phase-contrast images obtained with incoherent x-ray sources” Appl. Opt. 50 (2011) 1765-9

2010

Munro P R T, Ignatyev K, Speller R D and Olivo A “Source size and temporal coherence requirements of coded aperture type x-ray phase contrast imaging systems” Opt. Exp. 18 (2010) 19681-92

Munro P R T, Ignatyev K, Speller R D and Olivo A “Design of a novel phase contrast x-ray imaging system for mammography” Phys. Med. Biol. 55 (2010) 4169-85

Munro P R T, Ignatyev K, Speller R D and Olivo A “Limitations imposed by specimen phase gradients on the design of grating based x-ray phase contrast imaging systems” Appl. Opt. 49 (2010) 3860-3

Olivo A “Recent patents in x-ray phase contrast imaging”, Rec. Pat. Biomed. Eng. 3 (2010) 95-106 (review)

Munro P R T, Ignatyev K, Speller R D and Olivo A “The relationship between wave and geometrical optics models of coded aperture type x-ray phase contrast imaging systems”, Opt. Exp. 18 (2010) 4103-17

2009

Olivo A, Ignatyev K, Munro P R T and Speller R D “Design and realization of a coded-aperture based X-ray phase contrast imaging for homeland security applications”, Nucl. Instrum. Meth. A 610 (2009) 604-14

Olivo A and Speller R “Deconvolution of x-ray phase contrast images as a way to retrieve phase information lost due to insufficient resolution”, Phys. Med. Biol. 54 (2009) N347-54

Olivo A, Rigon L, Vinnicombe S J, Cheung K C, Ibison M and Speller R “Phase contrast imaging of breast tumours with synchrotron radiation” Applied Radiation and Isotopes 67 (2009) 1033-41

Olivo A, Bohndiek S E, Griffiths J A, Konstantinidis A and Speller R D “A non-free-space propagation x-ray phase contrast imaging method sensitive to phase effects in two directions simultaneously”, Appl. Phys. Lett. 94 (2009) 044108 (ALSO FEATURED IN: The Virtual Journal of Biological Physics Research, Vol 17, Issue 3, Feb 1, 2009)

2008

Olivo A, Chana D and Speller R “A preliminary investigation of the potential of phase contrast x-ray imaging in the field of homeland security”, J. Phys. D: Appl. Phys. 41 (2008) 225503

Olivo A and Speller R “Image formation principles in coded-aperture based x-ray phase contrast imaging” Phys. Med. Biol. 53 (2008) 6461-74

2007

Olivo A and Speller R “Modelling of a novel x-ray phase contrast imaging technique based on coded apertures” Phys. Med. Biol. 52 (2007) 6555-73

Olivo A, Arvanitis C, Bohndiek S, Clark A, Prydderch M, Turchetta R and Speller R “First evidence of phase contrast imaging with laboratory sources and active pixel sensors” Nucl. Instrum. Meth. A 581 (2007) 776-82

Olivo A and Speller R “A coded-aperture technique allowing x-ray phase contrast imaging with laboratory sources” Appl. Phys. Lett. 91 (2007) 074106

2006

Olivo A and Speller R “Experimental validation of a simple model capable of predicting the phase contrast imaging capabilities of any x-ray imaging system” Phys. Med. Biol. 51 (2006)  3015-30

---

Refereed Conference Proceedings

2017

Chen Y, Guan H, Hagen C K, Olivo A and Anastasio M A “A joint-reconstruction approach for single-shot edge illumination x-ray phase-contrast tomography”, Proc. SPIE (Physics of Medical Imaging) 10132 (2017) 1013217

2016

Endrizzi M, Astolfo A, Price B, Haig I and Olivo A “Asymmetric masks for large field-of-view and high-energy X-ray phase contrast imaging”, JINST 11 (2016) C12009 (Proceedings of 18th IWORID)

Astolfo A, Endrizzi M, Price G, Haig H and Olivo A “The first large area, high x-ray energy phase contrast prototype fpr enhanced detection of threat object in baggage screening”, Proc. SPIE (“Optics and Photonics for Counterterrorism, Crime Fighting, and Defence XII) 9995, 999504

Hagen C K, Maghsoudlou P, Totonelli G, Diemoz P C, Endrizzi M, Zamir A, Coan P, Bravin A, De Coppi P and Olivo A “Strategies for fast and low-dose laboratory-based phase contrast tomography for microstructural scaffold analysis in tissue engineering”, Proc. SPIE (“Developments in X-Ray Tomography X”) 9967 (2016), 996705

Zamir A, Hagen C K, Diemoz P C, Endrizzi M, Vittoria FA, Urbani L, De Coppi P and Olivo A “Increased robustness and speed in low-dose phase-contrast tomography with laboratory sources”, Proc. SPIE (“Developments in X-Ray Tomography X”) 9967 (2016), 996716

Endrizzi M, Astolfo A, Brice B, Haig I and Olivo A “Large field-of-view asymmetric masks for high-energy x-ray phase imaging with standard x-ray tube” Proc. SPIE (“Advances in laboratory-based x-ray sources, optics and applications V”) 9964 (2016), 99640A

Hagen C K, Zamir A, Diemoz P C, Endrizzi M, Vittoria F A, Magshoudlou P, Coan P, Bravin A, De Coppi P and Olivo A “Opportunities for phase-based computed tomography in the laboratory”, Proceedings of the 4th International Conference on Image Formation in X-Ray Computed Tomography (Bamberg, Germany, Jul 2016), pp. 363-6

2015

Cipiccia S, Reboredo D, Vittoria F A, Welsh G H, Grant P, Grant D W, Brunetti E, Wiggins S M, Olivo A and Jaroszynski D A “Laser-wakefield accelerators form medical phase contrast imaging: Monte Carlo simulations and experimental studies”, Proc. SPIE (Laser Acceleration of Electrons, Protons and Ions III) 9514 (2015), 951417

P. C. Diemoz, M. Endrizzi, C. K. Hagen, F. A. Vittoria and A. Olivo “Angular sensitivity and spatial resolution in edge illumination X-ray phase-contrast imaging”, Nucl. Instrum. Meth. A 784 (2015) 538-41

P. C. Diemoz, M. Endrizzi, F. A. Vittoria, C. K. Hagen, G. Kallon, D. Basta, M. Marenzana, P. Delogu, A, Vincenzi, L. De Ruvo, G. Spandre, A, Brez, R. Bellazzini and A. Olivo “Laboratory implementation of edge illumination X-ray phase contrast imaging with energy-resolved detectors”, Proc. SPIE 9412 (2015) 94120K

2014

Endrizzi M, Diemoz P C, Hagen C K, Millard T P, Vittoria F A, Wagner U H, Rau C, Robinson I K and Olivo A, “Laboratory-based edge-illumination phase-contrast imaging: dark-field retrieval and high-resolution implementations”, 2014 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) 7431019

Hagen C K, Zamir A, Diemoz P C, Endrizzi M, Kennedy F, Jager R H and Olivo A “Low-dose x-ray phase contrast tomography: experimental setup, image reconstruction and applications in biomedicine”, 2014 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) 7430971

Diemoz P C, Endrizzi M, Hagen C K, Vittoria F A, Millard T P and Olivo A “Optimisation of sensitivity, dose and spatial resolution in edge-illumination x-ray phase contrast imaging”, 2014 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) 7430970

M. Endrizzi, P. C. Diemoz, C. K. Hagen, F. A. Vittoria, P. R. T. Munro, L. Rigon, D. Dreossi, F. Arfelli, F. C. M. Lopez, R. Longo, M. Marenzana, P. Delogu, A. Vincenzi, L. De Ruvo, G. Spandre, A. Brez, R. Bellazzini and A Olivo. “Edge-illumination x-ray phase contrast imaging: matching the imaging method to the detector technology”, JINST 9 (2014) C11004

C. K. Hagen, P. C. Diemoz, M. Endrizzi, L. Rigon, D. Dreossi, F. Arfelli, F. M. C. Lopez, R. Longo and A. Olivo “Quantitative edge illumination x-ray phase contrast tomography”, Proc. SPIE 9212 (2014) 921205

A. Olivo, C. K. Hagen, T. P. Millard, F. Vittoria, P. C. Diemoz and M. Endrizzi “Simultaneous implementation of low dose and high sensitivity capabilities in differential phase contrast and dark-field imaging with laboratory x-ray sources”, Proc. SPIE 9033 (2014) 90330E

P. C. Diemoz, M. Endrizzi, C. K. Hagen, C. Rau, A. Bravin, R. D. Speller, I. K. Robinson and A. Olivo “Edge illumination X-ray phase-contrast imaging: nanoradian sensitivity at synchrotrons and translation to conventional sources”, JPCS 499 (2014) 012006

C. K. Hagen, P. C. Diemoz, M. Endrizzi, P. R. T. Munro, M. B. Szafraniec, T. P. Millard, R. Speller and A. Olivo “A laboratory-based x-ray phase contrast imaging scanner with applications in biomedical and non-medical disciplines”, Int. J. Mod. Phys: Conf. Series 27 (2014) 1460150

A. Olivo and I. Robinson, “Taking x-ray phase contrast imaging into mainstream applications” and its satellite workshop “Real and reciprocal space x-ray imaging”, Phil. Trans. R. Soc. A 372 (2014) 20130359

P. R. T. Munro, M. Endrizzi, P. C. Diemoz, C. K. Hagen, M. B. Szafraniec, T. P. Millard C. E. Zapata, R. D. Speller and A. Olivo “Medicine, material science and security: the versatility of the coded-aperture approach”, Phil. Trans. R. Soc. A 372 (2014) 20130029

P. C. Diemoz, M. Endrizzi, A. Bravin, I. K. Robinson and A. Olivo “Sensitivity of edge-illumination phase-contrast imaging”, Phil. Trans. R. Soc. A 372 (2014) 20130128

M. Marenzana, C. K. Hagen, P. Das Neves Borges, M. Endrizzi, M. B. Szafraniec, T. L. Vincent, L. Rigon, F. Arfelli, R-H. Menk and A. Olivo “Synchrotron and laboratory-based x-ray phase-contrast imaging for imaging mouse articular cartilage in the absence of radiopaque contrast agents”, Phil. Trans. R. Soc. A 372 (2014) 20130127

2013

M. Endrizzi, P. C. Diemoz, P. R. T. Munro, C. K. Hagen, M. B. Szafraniec, T. P. Millard, C. E. Zapata, R. D. Speller and A. Olivo. “Applications of a non-interferometric x-ray phase contrast imaging method with both synchrotron and conventional sources” JINST 8 (2013) C05008

P. C. Diemoz, M. Endrizzi, C. E. Zapata, A. Bravin, R. D. Speller, I. K. Robinson and A. Olivo “Improved sensitivity at synchrotrons using edge illumination x-ray phase-contrast imaging”, JINST 8 (2013) C06002

M. Endrizzi, P. C. Diemoz, M. B. Szafraniec, C. K. Hagen, T. P. Millard, C. E. Zapata, P. R. T. Munro, K. Ignatyev, M. Marenzana, R. D. Speller and A. Olivo. “Edge illumination and coded-aperture X-ray phase-contrast imaging: increased sensitivity at synchrotrons and lab-based translations into medicine, biology and material science”, Proc. SPIE 8668 (2013) 866812

2012

P. R. T. Munro, K. Ignatyev, P. C. Diemoz, M. B. Szafraniec, C. K. Hagen, T. P. Millard, C. E. Zapata, R. D. Speller and A. Olivo. “ ‘Edge-illumination’ in x-ray phase contrast imaging”, Proceedings of the 1st International Workshop on X-Ray and Neutron Phase Imaging with Gratings (XNPIG), Tokyo 2012, AIP Conf. Proc. 1466 (2012), 118-23

2011

K. Ignatyev, P. R. T. Munro, R. D. Speller and A. Olivo, “Phase Contrast Imaging with coded apertures using laboratory-based X-ray sources, Proceedings of the 10^th International Conference on X-Ray Microscopy (Chicago 2010), AIP Conf. Proc. 1365 (2011) 254-7

P. R. T. Munro, K. Ignatyev, R. Speller and A. Olivo “Design of a novel phase contrast X-ray imaging system for mammography”, Nucl. Instrum. Meth. A 652 (2011) 824-8

A. Olivo, K. Ignatyev, P. R. T. Munro, and R. D. Speller “A coded-aperture based method allowing non-interferometric phase contrast imaging with incoherent X-ray sources”, Nucl. Instrum. Meth. A 648 (2011) S28-31

2010

K. Ignatyev, P. R. T. Munro, R. D. Speller and A. Olivo, “First X-ray phase contrast images obtained with conventional x-ray source under exposure conditions compatible with real-world applications, Proceedings of the IEEE NNS&MIC 2010 conference record, 889-91

K Ignatyev, P Munro, R Speller and A. Olivo “X-ray Phase Contrast Imaging with coded apertures for next generation baggage scanning systems”, Proceedings of the IEEE International Conference on Technologies for Homeland Security (HST) (2010), pp. 292-295

2008

Olivo A and Speller R “A novel x-ray imaging technique based on coded apertures making phase contrast images feasible with conventional sources” proceedings of the IEEE NNS&MIC 2008 conference record pp. 1447-50

2007

Olivo A and Speller R “Polychromatic phase contrast imaging as a basic step towards a widespread application of the technique” Nucl. Instrum. Meth. A 580 (2007) 1079-82

Endrizzi M, Olivo A, Diemoz PC, Millard T and Vittoria A “X-ray imaging – dark field imaging”, WO/2014/202949

Ignatyev K, Olivo A, Munro PRT, and Speller RD, “X-Ray Imaging” (former “Phase Imaging: method for highly accurate automated geometric alignment of masks and detector”), WO/2013/011316

Munro PRT, Olivo A, Ignatyev K, and Speller RD, “Phase Imaging”, WO/2013/011317

Olivo A and Speller R (2006), “Phase contrast imaging”, WO/2008/029107

2017

XPCI: X-Ray Phase Contrast Imaging, X-rays, a tool for science and technology: interaction with matter, detection techniques, applications. Politecnico di Milano, Italy, Feb 20-21 2017 (Olivo)

“Edge illumination X-ray phase-contrast imaging: principles and applications”, Kioloa NSW, 7-10 March 2017 (Endrizzi)

2016

Status and perspectives of edge-illumination x-ray phase contrast imaging, Nikon Metrology UK Headquarters, Tring, Herts, 24 Feb 2016 (Olivo)

Practical x-ray phase contrast imaging, KTN workshop on Advanced Sensing for Biosciences and Healthcare, Ambassador Hotel, London, 16 Mar 2016 (Olivo)

Edge illumination x-ray phase contrast imaging: state of the art and new developments, U.S. Food and Drug Administration, Silver Spring, Maryland, March 17 2016 (Diemoz)

X-ray phase contrast imaging (XPCI) and its potential applications in cancer research, UCL Cancer Institute, 21 April 2016 (Olivo)

Enhanced detection of weapons and explosives through x-ray phase contrast and dark field imaging, Advanced Development for Security Applications (ASDA) Workshop 14, Northeastern University, Boston, Mass, May 10-11 2016 (Olivo)

Can the use of x-rays be transformed 120 years after their discovery? X-ray phase contrast imaging and its translation towards clinical and other applications, Medical Image Computing Summer School (MedICSS 2016), UCL, Aug 18-22 2016 (Olivo)

Origins, development and current state-of-the-art of edge-illumination x-ray phase contrast imaging, MART-3D: Advanced summer school on reconstruction methods in tomography, Carcans, Bordeaux, France Sept 12-16 2016 (Olivo)

Prospective use of laser-driven sources for x-ray phase contrast imaging, uroNNAC and EuPRAXIA workshop on pilot applications of electron plasma accelarators (PAEPA), Ecole Polytechnique, Palaiseau, France, Oct 11-13 2016 (Olivo)

Edge-illumination – state-of-the-art and future perspectives of an incoherent x-ray phase contrast imaging method, ANKA Seminar Series, Karlsruhe Institute of Technology, Karlsruhe, Germany, Nov 7 2016 (Olivo)

Phase contrast: a different approach to the use of x-ray imaging for biomedical applications, CMM Seminar Series, Faculty of Biomedical Sciences, University of Bristol, UK, Nov 15 2016 (Olivo)

State-of-the-art and future perspectives of a non-interferometric incoherent x-ray phase contrast imaging method, SFB Seminar Series, Faculty of Physics, Georg-August-Universitat Gottingen, Germany, Dec 1 2016 (Olivo)

Translation of x-ray phase-contrast imaging from synchrotron to laboratory using the edge illumination technique”, IOP Medical Physics Group Annual Scientific and Networking Meeting – Up and Coming Techniques in Medical Physics Translated into Clinical Practice, Institute of Physics, London, UK, Dec 2 2016 (Endrizzi)

2015

Artefacts in X-Ray Tomography, 9-13 Feb 2015, Leiden, Netherlands (Hagen)

Translating edge-illumination based x-ray phase contrast imaging into in vivo clinical applications, Siemens HQs, Erlangen, Germany, Apr 13 2015 (Olivo)

Translating edge-illumination based x-ray phase contrast imaging into mammography and other applications, GE Healthcare HQs, Buc, France, Apr 22 2015 (Olivo)

Methods for fast tomography in edge illumination X-ray phase-contrast imaging and other differential phase techniques, International workshop on “Challenges in X-ray tomography” (part of the EXTREMA COST action) Grenoble, France, May 18-20 2015 (Diemoz)

Phase contrast imaging and tomography with hard x-rays – prospective applications to various areas including electrochemical devices, STFC Global Challenge Network in Batteries and Electrochemical Energy Devices, Cosener’s House, Abingdon, Jun 30 – Jul 1 2015 (Olivo)

Conventional vs. phase-based x-ray imaging: where does the transformative potential of the latter come from, and can we exploit it in clinical applications? Medical Image Computing Summer School (MedICSS 2015), UCL, Aug 10-14 2015 (Olivo)

Removing the roadblocks to clinical translation of x-ray phase contrast imaging using the edge-illumination method, IEEE EMBS Conference, Mini-symposium on “Frontiers in Phase Contrast X-ray imaging for Biomedical Application”, Milan, Italy, Aug 26 2015 (Olivo)

Towards the translation of x-ray phase contrast imaging into clinical applications, IPEM Medical Physics and Biomedical Engineering Conference 2015, Liverpool, UK, Sept 8-10 2015 (Olivo)

Portable x-ray phase contrast tomography (a.k.a. “incoherent approaches to x-ray phase contrast imaging with conventional x-ray sources”), International Workshop on Imaging, Varenna (Lecco), Italy, Sept 7-10 2015 (Olivo)

Using X-ray imaging to improve quantitative photoacoustic tomography of small animals, Workshop on Quantitative Photoacoustic Imaging, Berlin, Germany, Sept 10-11 2015 (Munro)

Is relaxing the coherence requirements a necessary step to enable a clinical translation of x-ray phase contrast imaging? (keynote), 8^th International Symposium on Medical Applications of Synchrotron Radiation (MASR), Grenoble & Villard De Lans, France, October 5-9 2015 (Olivo).

Multi-modal phase-based x-ray imaging: detecting the undetectable, John Adams Institute for Accelerator Science, University of Oxford, 29 Oct 2015 (Olivo)

Seeing invisible things with X-Rays, “Alumnorum Colloquia” series, Department of Physics, University of Trieste, 17 Dec 2015 (Olivo)

2014

Enhancing phase sensitivity through edge-illumination, ESRF Users meeting 2014, Grenoble, Feb 3-5 2014 (Olivo)

Coded-aperture x-ray phase contrast imaging, Horizon 2020 Secure Society UK, London Feb 18 2014 (Endrizzi)

Enhanced image sensitivity using edge illumination X-ray phase-contrast imaging: from synchrotrons to X-ray tubes”, V Topical Day on Imaging and Image Analysys, EMPA, Dubendorf, Switzerland, April 8 2014 (Diemoz)

Edge illumination x-ray phase contrast imaging – from planar to tomography, “Vision Lecture”, Vision Lab (Antwerp, Belgium), 9-11 April 2014  (Hagen)

Edge-illumination XPCi: an intrinsically incoherent phase contrast method, Coherent and incoherent x-ray imaging and tomography, EU “COST” Actions, La Sapienza, Rome, Italy, May 14-16 2014 (Olivo)

X-ray phase contrast imaging (XPCI) for small animal CT based on edge-illumination/coded aperture”, National Cancer Institute, Frederick, MD, Aug 4 2014 (C-M. Tang - CEO Creatv Microtech - on behalf of the UCL AXIm Group)

Dark field, microscopic and tomographic implementations of edge-illumination phase contrast imaging”, Diamond SR User Meeting 2014, Diamond Light Source, Oxfordshire, 3-4 Sept 2014 (Endrizzi)

High sensitivity and flexibility of the Edge Illumination phase contrast approach implemented with coherent sources”, Diamond SR User Meeting 2014, Diamond Light Source, Oxfordshire, 3-4 Sept 2014 (Vittoria)

Current status and future perspective of edge-illumination x-ray phase contrast imaging”, XTOP 2014, Villard De Lans, France, Sept 14-19 2014 (Olivo)

Detecting explosives and weapons via high-throughput multi-modal x-ray imaging, IRC Showcase, The Royal Institution of Great Britain, London, UK, Sept 23 2014 (Olivo)

Making the invisible visible – x-ray phase contrast imaging, Institute of Biomedical Engineering, University of Oxford, Nov 11 2014 (Olivo)

Tomographic x-ray phase contrast imaging with the edge illumination method, Thematic Workshop on Advanced X-Ray Imaging, 11-12 Dec 2014, Trieste, Italy (Hagen)

2013

Medicine, material science and security: the versatility of the coded-aperture approach, Taking x-ray phase contrast imaging into mainstream applications, The Royal Society, London, UK, Feb 11-12 2013 (Munro)

The UCL X-Ray Phase Contrast Imaging Method: enhanced sensitivity at synchrotrons and easier translation to conventional sources, UCL Centre for Neuroimaging Techniques, Institute of Neurology, 7 Mar 2013 (Olivo)

Phase contrast imaging with conventional x-ray sources at acceptable dose levels and exposure times, Annual Meeting of the American Physical Society (“March” Meeting), March 18-22 2013 Baltimore, MD (Olivo)

X-ray phase contrast tomography using edge illumination, UCL Centre for Inverse Problems: Opening Meeting, London, UK, 18-21 March 2013 (Hagen)

How to achieve acceptable dose levels and exposure times in Phase contrast imaging with conventional x-ray sources, Creatv Microtech Headquarters, Potomac, MD, March 20 2013 (Olivo)

X-Ray Phase Contrast Imaging using conventional sources, University of Western Australia, Perth, March 21, 2013 (Munro)

A comparison between coded-aperture and grating-based x-ray phase contrast methods: why the former are more suited for clinical translation, Dexela/Perkin Elmer London HQs, March 28 2013 (Olivo)

Why could the edge-illumination/coded-aperture x-ray phase contrast imaging method allow for an easier translation into medical and other applications?, Faculty of Medicine, University of Saskatchewan, Saskatoon, Canada, May 9 2013 (Olivo)

X-ray phase-contrast imaging with edge illumination and coded aperture systems, University of Pisa, 22 July 2013 (Endrizzi)

 Why could the edge-illuminaiton/coded aperture x-ray phase contrast imaging (XPCi) method allow for an easier translation into medical and other applications?, FDA Headquarters, Silver Spring, MD, Jul 24 2013 (C-M. Tang - CEO Creatv Microtech - on behalf of the UCL AXIm Group)

Sviluppo delle tecnologie a contrasto di fase per applicazioni mediche e biologiche - dai sincrotroni alle sorgenti X convenzionali (closing keynote lecture), 99^th National SIF (Italian Society of Physics) Congress, Trieste, Italy, Sept 23-27 2013 (Olivo)

X-ray phase contrast imaging – detecting the undetectable, Biological and Soft System Sector, Cavendish Laboratory, Cambridge University Nov 8^th 2013 (Olivo).

Edge-illumination phase contrast imaging with conventional x-ray sources: simplified setup, low dose, high stability, acceptable exposure times, Food and Drug Administration Headquarters, Silver Spring, MD, 9 Dec 2013 (Olivo)

2012

“Edge illumination” in x-ray phase contrast imaging, International Workshop on X-ray and Neutron Phase Imaging with Gratings (XNPIG), Mational Museum of Emerging Science and Innovation (Miraikan), Tokyo, Japan, Mar 5-7 2012 (Olivo)

Seeing invisible things with x-rays: x-ray phase contrast imaging, IBME “MedTech” Week, June 18-22 2012, UCL, London, UK (Olivo)

Applications of a non-interferometric x-ray phase contrast imaging method with both synchrotron and conventional sources (plenary), 7^th International Symposium on Medical Applications of Synchrotron Radiation (MASR), Shanghai Synchrotron Radiation Facility (SSRF), October 17-20 2012 (Olivo).

Seeing invisible things (possibly while in full possession of your mental capacities): x-ray phase-contrast imaging, Kings College London, Centre for Neuroimaging Science, Nov 20 2012 (Olivo)

2011

Coded-aperture x-ray phase contrast imaging: a non-interferometric method working with conventional x-ray sources, ESRF Tuesday Events, ESRF, Grenoble, France, Mar 1 2011 (Olivo)

Coded-aperture X-ray phase contrast imaging: a non-interferometric method suitable for use with synchrotron radiation and conventional sources, Workshop on phase modulation methods, Harwell Research Complex, Didcot, UK, June 23 2011 (Olivo)

A new generation of baggage scanning systems based on x-ray phase contrast imaging (opening lecture), Gordon Research Conference on detecting illicit substances, Barga, Lucca Italy, June 26–30 2011 (Olivo)

Medical applications of a novel x-ray phase contrast imaging method working with conventional sources (keynote), Bioengineering11, Queen Mary, University of London, London Sept 12-13 2011 (Olivo)

The development of innovative imaging technologies to probe the mechanisms of tissue regeneration in vivo, Summit on Regenerative Medicine - an Italy-UK workshop organised by the Italian Embassy in London and the School of Science Technology and Health of the University Campus Suffolk, UCS, Ipswich, UK Dec 12 2011 (Olivo)

2010

X-Ray phase contrast imaging – applications to breast imaging and other fields, ANRAD Headquarters, Montreal, Canada, 9 March 2010 (Olivo)

2009

Phase contrast x-ray imaging of breast tumours, UKRC2009, Manchester Central, June 9^th 2009 (Olivo)

New ways of using x-rays to detect explosives and other threat objects, UCL Security Workshop, July 16^th 2009 (Olivo)

Leading edge requirements for diagnostic imaging, STFC roundtable on “opportunities for CMOS detectors in medical imaging”, Milton Hill House, Steventon, August 20^th 2009 (Olivo)

Advances in x-ray phase contrast imaging (Keynote), Imaging Techniques in Biomedical Sciences (ITBS 2009), Milos Island, Greece, 13-16 Sept 2009 (Olivo)

2008

Imaging with synchrotron radiation, Oxford Summer School on Synchrotron Radiation, St. Hilda’s College, Oxford, Aug 13^th 2008 (Olivo)

An overview of phase contrast imaging methods and their biological applications, UK Synchrotron Radiation User Meeting, Daresbury Laboratory, UK, 11-12 September 2008 (Olivo)

A novel x-ray imaging technique based on coded apertures making phase contrast imaging feasible with conventional sources, Philips Research Europe, Hamburg, Germany, November 18^th 2008 (Olivo)

2007

An innovative technique making phase contrast imaging feasible with conventional x-ray sources, e2v Technologies Headquarters, Chelmsford, Essex, UK, February 19^th 2007 (Olivo)

Una tecnica innovative per l’imaging a raggi X in contrasto di fase con sorgenti convenzionali, University of Trieste, Department of Physics, October 26^th 2007 (Olivo)

2016

“X-ray phase imaging: a new tool for biomedical imaging”, UK-Canada Frontiers of Science, Whistler Canada, March 14-16, 2016 (Munro)

Towards the clinical translation of x-ray phase contrast imaging, UKRC 2016, Liverpool ACC June 6-8 2016 (Olivo)

 “Fast, scalable, low-dose phase-based x-ray imaging with conventional sources”, ATTRACT TWS Symposium, ESADE, Barcelona, Spain, Jun 30-Jul 1 2016 (Endrizzi)

 “Asymmetric masks for large field-of-view and high-energy x-ray phase contrast imaging”, IWORID 2016, AXA Convention Centre, Barcelona, Spain, 3-7 July 2016 (Endrizzi)

 “X-ray phase contrast CT as a new modality for 3D, non-destructive analyses of tissue engineering scaffolds”, 16th Annual Meeting of the Tissue and Cell Engineering Society (TCES), London (UK), 4-6 July 2016 (Hagen)

 “Opportunities for phase-based computed tomography in the laboratory”, 4th International Conference on Image Formation in X-Ray Computed Tomography, Bamberg (GER), 18-22 July 2016 (Hagen)

 “Simple and robust synchrotron and laboratory solutions for high-resolution multimodal x-ray phase-based imaging”, International Conference on X-Ray Microscopy 2016, University of Oxford, UK, Aug 15-29 2016 (Endrizzi)

 “Small angle x-ray scattering with edge illumination”, International Conference on X-Ray Microscopy 2016, University of Oxford, UK, Aug 15-29 2016 (Modregger)

 “Large field-of-view asymmetric masks for high-energy x-ray phase imaging with standard x-ray tube”, SPIE Optics + Photonics, San Diego (US), 28 Aug-1 Sept 2016 (Endrizzi)

 “Fast and low-dose laboratory-based phase contrast tomography for microstructural scaffold analysis in tissue engineering”, SPIE Optical Engineering and Applications, Developments in X-Ray, San Diego (US), 29-31 August 2016 (Hagen/Endrizzi)

 “Increased roubustness and speed in low-dose phase-contrast tomography with laboratory sources”, SPIE Optical Engineering and Applications, Developments in X-Ray, San Diego (US), 29-31 August 2016 (Zamir)

 “High-energy low-dose mammography using edge illumination x-ray phase contrast imaging”, XTOP 2016, Brno, Czech Republic, Sept 4-8 2016 (Diemoz)

 “New laboratory implementations of edge illumination x-ray phase contrast imaging”, XTOP 2016, Brno, Czech Republic, Sept 4-8 2016 (Kallon)

“Recent advances in edge illumination x-ray phase contrast computed tomography”, Tomography for Scientific Advancement (ToScA2016), Bath, UK, Sept 6-7 2016 (Zamir)

“Scanning multi-modal x-ray phase-contrast for breast imaging, RAEng’s YRFM (Young Researchers’ Futures Meeting) 2016, Imperial College, London, UK, Sept 7-8 2016 (Endrizzi)

“Exploiting new physical quantities to detect concealed explosives using phase-based x-ray imaging”, Concealed Explosives Detection Workshop, Cambridge, UK, Sept 19-23 2016 (Astolfo)

“The first large area, high x-ray energy phase contrast prototype for enhanced detection of threat object in baggage screening”, SPIE Security + Defense, Edinburgh, UK, Sept 26-29 2016 (Astolfo)

“Recent developments in Edge Illumination x-ray phase contrast imaging: large field of view, fast tomographic scans, single mask approaches”, COST MP1203 General and Closing Meeting, Vouliagmeni, Greece, Oct 19-21 2016 (Vittoria)

“A large field-of-view multimodal x-ray phase contrast system for security scans and other applications”, IEEE NSS/MIC 2016, Strasbourg, France, Oct 29- Nov 5 2016 (Astolfo)

 “Fast, scalable, low-dose phase based x-ray imaging with conventional sources, 2nd ATTRACT TWD Symposium in Detection and Imaging Strasbourg, France, Nov 4-5 2016 (Astolfo)

2015

New implementations and prospective applications of Edge Illumination Phase Contrast CT” Lorentz workshop on “Artefacts in X-Ray Tomography, 9-13 Feb 2015, Leiden, Netherlands (Zamir)

Laboratory implementation of edge illumination X-ray phase contrast imaging with energy-resolved detectors, SPIE Medical Imaging 2015, Orlando, Florida, US 22-26 Feb 2015 (Diemoz)

X-ray phase contrast computed tomography: exploiting improved soft tissue contrast in 3D for biomedical applications”, Set for Britain 2015, The House of Commons, London, UK, Mar 9 2015 (Hagen)

An incoherent implementation of x-ray phase contrast imaging and tomography that maintains high sensitivity at low delivered doses, World Congress on Medical Physics and Biomedical Engineering, Toronto, Canada, Jun 7-12 2015 (Olivo)

Edge illumination x-ray phase contrast computed tomography: implementations at synchrotrons and in standard laboratories, International Conference on Computed Tomography of Materials and Structures (ICTMS), Quebec City, Canada, June 29 – July 3rd 2015 (Hagen)

Edge-illumination X-ray dark-field imaging for visualizing defects in composite structures, 18th International Conference on Composite Structures (ICCS18), Lisbon, Portugal, June 15-18 2015 (Endrizzi)

Approaches for x-ray phase imaging based on beam tracking and one-dimensional pthychography, Microscience and Microscopy Conference, Manchester Central, Manchester, UK, Jun 29-Jul 2 2015 (Vittoria)

Asymmetric masks for lab-based x-ray phase-contrast imaging, X-ray and Neutron Phase Imaging with Gratings, Natcher Conference Center, NIH, Bethesda, Maryland, USA, 8-11 Sept 2015 (Endrizzi)

On the effect of beam hardening on the dark-field signal”, X-ray and Neutron Phase Imaging with Gratings, Natcher Conference Center, NIH, Bethesda, Maryland, USA, 8-11 Sept 2015 (Vittoria)

Laboratory based edge illumination x-ray phase contrast imaging with 2D phase sensitivity, X-ray and Neutron Phase Imaging with Gratings, Natcher Conference Center, NIH, Bethesda, Maryland, USA, 8-11 Sept 2015 (Wesolowski)

Fast approaches to edge illumination x-ray phase contrast computed tomography”, X-ray and Neutron Phase Imaging with Gratings, Natcher Conference Center, NIH, Bethesda, Maryland, USA, 8-11 Sept 2015 (Hagen)

Edge illumination x-ray phase contrast computed tomography: recent developments and new applications, Medical Applications of Synchrotron Radiation (MASR), Grenoble/Villard de Lans, France, Oct 5-8 2015 (Hagen)

A single-image retrieval method for fast and low-dose applications of edge illumination X-ray phase contrast imaging, Medical Applications of Synchrotron Radiation (MASR), Grenoble/Villard de Lans, France Oct 5-8 2015 (Diemoz)

Edge illumination dark-field imaging: applications with conventional X-ray sources, achromaticity and high energy implementations, Medical Applications of Synchrotron Radiation (MASR), Grenoble/Villard de Lans, France Oct 5-8 2015 (Endrizzi)

Subpixel X-ray phase imaging using synchrotron Radiation, Medical Applications of Synchrotron Radiation (MASR), Grenoble/Villard de Lans, France Oct 5-8 2015 (Munro)

Detecting explosives and weapons via High-throughput multimodal x-ray imaging”, Defense Innovation, Technology Accelaration Challenges, Austin, TX (USA), Dec 1-3 2015 (Astolfo)

2014

Coded-aperture x-ray phase contrast imaging: retrieval of dark field images, XNPIG/IMXP 21-24 Jan 2014 Garmish-Partenkirchen (Endrizzi)

Sensitivity of the edge illumination method in both synchrotron and lab-based implementations, XNPIG/IMXP 21-24 Jan 2014 Garmish-Partenkirchen (Diemoz)

Sensitivity of edge illumination X-ray phase-contrast imaging in both synchrotron and lab-based implementations, ESRF Users meeting 2014, Grenoble, Feb 3-5 2014 (Diemoz)

Micro and Macroscopic implementations of edge-illumination x-ray phase contrast imaging for increased phase sensitivity, Zeiss visit, UCL, Feb 7 2014 (Olivo)

Tomographic edge illumination x-ray phase contrast imaging (EI XPCi), Lorentz workshop on “Advanced X-Ray Tomography” (Leiden, Netherlands), 10-14 February 2014 (Hagen)

Simultaneous implementation of low dose and high sensitivity capabilities in differential phase contrast and dark-field imaging with laboratory x-ray sources, SPIE Medical Imaging 2014, San Diego, California, US, Feb 15-20 2014 (Olivo)

Modelling signal from microbubbles using x-ray phase contrast, Workshop on Monte Carlo simulation tools for x-ray imaging and fluorescence, the ESRF, Grenoble, France, Feb 24-25 2014 (Millard)

Edge illumination x-ray phase-contrast imaging: enhanced phase sensitivity for synchrotron and laboratory applications, 2014 Symposium on Radiation Measurements and Applications (SORMA XV), Ann Arbor, Michigan, USA, 9-12 June 2014 (Diemoz)

Edge-illumination x-ray phase contrast imaging: matching the imaging method to the detector technology, IWORID 2014, Trieste, Italy, June22-26 2014 (Olivo)

Edge-illumination x-ray phase contrast tomography, workshop on “tomography of electrochemical devices”, UCL, 3 July 2014 (Hagen)

Edge-illumination hard X-ray dark-field imaging: developing microscopic and tomography applications, workshop on “tomography of electrochemical devices”, UCL, 3 July 2014 (Endrizzi)

Quantitative edge illumination x-ray phase contrast tomography, SPIE Optics + Photonics 2014 “Developments in X-Ray Tomography IX”, S. Diego Convention Centre, S. Diego, California, 17-21 Aug 2014 (Hagen)

Recent developments and applications of edge-illumination x-ray phase contrast imaging, MECbioeng14, Imperial College London, 10-11 Sept 2014 (Vittoria)

Dark-field and high-resolution phase-contrast imaging with a laboratory-based edge-illumination setup, 100th National Congress, Italian Physical Society, 23 Sept 2014, Pisa, Italy (Endrizzi)

Laboratory-based edge-illumination phase-contrast imaging: dark-field retrieval and high-resolution implementations, IEEE Medical Imaging Conference, Seattle (USA) 8-15 Nov 2014 (Endrizzi)

Optimization of sensitivity, dose and spatial resolution in edge illumination X-ray phase contrast imaging, IEEE Medical Imaging Conference, Seattle (USA), 8-15 Nov 2014 (Diemoz)

Low-dose x-ray phase contrast tomography: experimental setup, image reconstruction and applications in biomedicine”, IEEE Medical Imaging Conference, Seattle (USA) , 8-15 Nov 2014 (Hagen)

2013

Edge illumination and coded-aperture X-ray phase-contrast imaging: increased sensitivity at synchrotrons and lab-based translations into medicine, biology and materials science, SPIE Medical Imaging, Orlando, Florida, Feb 9-14 2013 (Endrizzi)

Synchrotron- and laboratory-based x-ray phase-contrast imaging for imaging mouse articular cartilage in the absence of radiopaque contrast agents, Taking x-ray phase contrast imaging into mainstream applications, The Royal Society, London, UK, Feb 11-12 2013 (Marenzana)

Sensitivity of edge illumination x-ray phase-contrast imaging, Taking x-ray phase contrast imaging into mainstream applications, The Royal Society, London, UK, Feb 11-12 2013 (Diemoz)

Low dose phase contrast and tomosynthesis with a conventional x-ray source, The Royal Society, London, UK, Feb 11-12 2013 (Szafraniec)

The UCL method for phase contrast imaging with conventional x-ray sources: simplified setup, low dose, high stability, acceptable exposure times, SIEMENS visit, UCL, Apr 23 2013 (Olivo)

Innovative high-resolution 3D phase imaging of decellularized esophagus reveals highly preserved extracellular matrix, 14^th Congress of the European Pediatric Surgeons’ Association, Leipzig, Germany, 5-8 June 2013 (Totonelli)

Laboratory-based X-Ray Phase Contrast Imaging: Applications in Medicine, Biology, Material Testing and Homeland Security, The 2013 International Conference on Applications of Nuclear Techniques (CRETE 13), Crete, Greece, June 23-29 2013 (Hagen)

X-ray phase contrast imaging using the edge illumination method, 7th UK & RI Postgraduate Conference in Biomedical Engineering and Medical Physics (PGBiomed 2013), University of Surrey, July 9-11 2013 (Millard)

A quantitative study on the performance of PICASSO detector in phase contrast imaging with synchrotron radiation, 7th UK & RI Postgraduate Conference in Biomedical Engineering and Medical Physics (PGBiomed 2013), University of Surrey, July 9-11 2013 (Longo)

Innovative high-resolution 3D phase imaging for defining ultrastructural characteristics of intestinal acellular matrix, 60^th anniversary BAPS congress, Bournemouth International Centre, July 16-19 2013 (Totonelli)

Edge Illumination X-ray Phase-Contrast Imaging: Nanoradian sensitivity at Synchrotrons and Translation to Conventional Sources, 22^nd International Congress on X-Ray Optics and Microanalysis (ICXOM 2013), Hamburg, Germany, Sept 2-6 2013 (Diemoz)

Edge illumination x-ray phase-contrast imaging: nanoradian angular resolution at synchrotrons and translation to conventional sources”, 21^st SILS (Società Italiana Luce di Sincrotrone) Congress, Milan, Italy, Sept 11-13 2013 (Diemoz)

Prospects for Dose Reduction in Breast Imaging and Beyond through an X-Ray Phase-Contrast Imaging Method Suitable For Clinical Translation”, II Mediterranean Thematic Workshop in Advanced Molecular Imaging (MEDAMI 2013), Mallorca, Spain, 26-29 Sept 2013 (Endrizzi)

A one dimensional ptychographic engine and its relation with direct-space phase contrast imaging methods, X-ray lasers in biology, The Royal Society, London, UK, Oct 14-15 2013 (Vittoria)

An X-Ray Phase Contrast Method Suitable For Clinical Translation, RSNA 99th Scientific Assembly and Annual Meeting, December 1-6, 2013, McCormick Place, Chicago, Illinois (Olivo)

2012

Preliminary investigation and possible implementations of 3D coded aperture x-ray phase contrast imaging, Bioengineering 11, QMUL, London, UK, 12-13 September 2012 (Szafraniec)

Structured illumination via coded-apertures for x-ray phase contrast imaging with incoherent sources, 1^st interdisciplinary European symposium on biomedical applications of x-ray phase contrast imaging, Hotel Riessersee, Garmisch-Patenkirchen, Germany, Jan 13 2012 (Olivo)

Signal amplification and phase retrieval at very high energies with the edge illumination technique, 1^st interdisciplinary European symposium on biomedical applications of x-ray phase contrast imaging, Hotel Riessersee, Garmisch-Patenkirchen, Germany, Jan 13 2012 (Diemoz)

Development of a 2D and 3D coded aperture x-ray phase contrast imaging system, State of the art and future challenges in x-ray computed tomography for mechanical behaviour assessment, Southampton, Jan 26 2012 (Hagen)

A quantitative study of coded-aperture based X-ray Phase Contrast imaging with synchrotron radiation, 5^th Alpe-Adria Medical Physics Meeting and EFOMP Meeting, Trieste, Italy, May 3-6 2012 (Longo)

Laboratory based x-ray scatter imaging - x-ray dark field imaging, Bioengineering 2012, Said Business School, Oxford, 6-7 September 2012 (Millard)

The role of the Hilbert transform in phase-sensitive x-ray computed tomography, IMA conference “Maths Meets Medicine”, London, UK, 17-19 September 2012 (Hagen)

An X-ray phase-contrast method with nanoradian angular resolution, MASR (Medical Applications of Synchrotron Radiation) 2012, Shanghai, 17-20 Oct 2012 (Diemoz)

2011

X-ray phase contrast imaging for enhanced threat detection, RCUK Global Uncertainties Programme Strategic Plan Consultation, Park Crescent Conference Centre, London, Jan 31 2011 (Olivo)

Transforming the use of x-rays in science and society, Set for Britain 2011, The House of Commons, London, UK, Mar 14 2011 (Olivo)

A different take on x-ray phase contrast imaging with conventional sources, Gordon Research Conference on X-ray Science, Colby College, Waterville, ME, Aug 7-12 2011 (Olivo)

Phase contrast mammography: earlier threat detection, Joint STFC Futures & BIR Cancer Care Workshop, RAL, Harwell, Oxfordshire, UK Oct 5-6 2011 (Olivo)

X-Ray Phase Contrast Imaging for Increase Threat Detection and Reduced False Positives in Baggage Scanning Systems, IRC in Explosives and Weapons Detection Showcase, Central Hall Westminster, London, Nov 17^th 2011 (Ignatyev)

2010

Design of a novel phase contrast X-ray imaging system for mammography”, Symposium on Radiation Measurements and Applications (SORMA) XII, University of Michigan, Ann Arbor, US, May 24-27 2010 (Munro)

A coded-aperture method allowing non-interferometric X-ray phase contrast imaging with incoherent sources, Imaging 2010, Stockholm, Sweden, June 8-11, 2010 (Olivo)

Phase Contrast Imaging with Coded Apertures Using Laboratory-Based X-ray Sources, 10th International Conference on X-ray microscopy, Chicago, IL, 15-20 Aug 2010 (Ignatyev)

First x-ray phase contrast images obtained with conventional x-ray source under exposure conditions compatible with real-world applications, 2010 IEEE Nuclear Science Symposium and Medical Imaging Conference (2010 NSS/MIC), Knoxville, TN, 30 Oct- 6 Nov 2010 (Ignatyev)

X-ray Phase Contrast Imaging with Coded Apertures for next generation baggage scanning systems”, 2010 IEEE International Conference on Technologies for Homeland Security, Waltham, MA, 8-10 Nov 2010 (Ignatyev)

A new generation of baggage scanning systems based on X-ray Phase Contrast Imaging”, INSTINCT-TD2 Showcase Event, Crawley, UK, Dec 1-2 2010 (Ignatyev)

2009

A new technique based on coded apertures capable of taking x-ray phase contrast imaging into clinical use, World Congress on Medical Physics and Biomedical Engineering, Munich, 7-12 Sept 2009 (Olivo)

2008

A novel x-ray imaging technique based on coded apertures making phase contrast imaging feasible with conventional sources, IEEE NSS & MIC Conference, Dresden, Germany, 19-25 October 2008 (Olivo)

2007

A coded-aperture technique opening the way to x-ray phase contrast imaging with conventional sources, STFC/Kite Club Healthcare Technology Forum, Institute of Physics, London, 25^th September 2007 (Olivo)

2006

Polychromatic phase contrast as a basic step towards a widespread application of the technique, Imaging 2006, Stockholm, Sweden, June 26-30, 2006 (Olivo)

2017

“Improving the outcomes of oesophageal interventions through novel x-ray based imaging methods”, EPSRC Healthcare Impact Partnership

“Multi-modal imaging for characterization and testing of advanced materials”, EPSRC “CASE” studentship (with Nikon co-funding)

“New Zeff/SCATTeff from 8-dimensional data acquired in a single scan”, IRC (HOSDB, DfT and other authorities)

“X-ray elastography: a novel approach to breast imaging”, EPSRC First Grant.

Exploiting the DART reconstruction algorithm for phase-based computed tomography”, Royal Society International Exchanges travel award

2017 Stjepan Marcelja Visiting Fellowship, Australian National University

2016

“Efficient intraoperative detection of tumour margins through x-ray phase contrast CT”, Wellcome/DoH HICF scheme

“Fast and cost-effective x-ray phase contrast tomography for image guided therapy”, EPSRC Doctoral Prize Fellowship

“Proof-of-concept investigation of the potential of edge-illumination x-ray phase contrast for pre-clinical imaging”, Industrial Grant from Perkin Elmer

2015

“Next generation, quantitative, pre-clinical imaging”, Royal Society University Research Fellowship

“Next generation X-ray detector”, UCL Faculty of Engineering strategic equipment grant proposal

 “A novel approach to CT and micro-CT for phase-based x-ray imaging and beyond”, EPSRC Doctoral Prize Fellowship

 “Laboratory-based x-ray dark-field microscopy and microtomography”, Royal Academy of Engineering Research Fellowship

 “Evaluation of edge-illumination based phase contrast and dark-field CT for commercialization of the method in biological and industrial applications”, Industrial grant form NIKON

 “UCL cross-disciplinary advanced X-ray imaging centre”, EPSRC “Strategic Equipment” bid

 “Imaging ultra-small angle x-ray scattering with edge-illumination: exploiting sub-pixel information in medical diagnostics, materials science and security screening”, EU-Funded Marie Curie Intra-European Fellowships

 “Detecting explosives and weapons via high-throughput multi-modal x-ray imaging – full prototype”, IRC - (Home Office, DfT and other authorities)

2014

 “Investigating the potential of edge-illumination based x-ray phase contrast imaging in the field of angiography”, EPSRC “CASE” studentship (with Siemens co-funding)

 “A UK facility for 4-D and correlative imaging using x-ray nano computed tomography”, EPSRC Strategic Equipment Investments (led by Dr. Paul Shearing, UCL Chem Eng – A. Olivo co-I)

 “Evaluation of edge-illumination based dark-field imaging for commercialization of the method in industrial applications”, Industrial grant form NIKON

 “Translation of quantitative 2D coded aperture phase contrast imaging from the synchrotron to the preclinical laboratory”, Burroughs Wellcome Fund (led by Dr. Mike Wesolowski, University of Saskatchewan – A. Olivo co-I)

 “Detecting explosives and weapons via high-throughput multi-modal x-ray imaging – feasibility phase”, IRC (Home Office, DfT and other authorities)

 “Towards a clinical translation of x-ray phase contrast imaging to angiography”, UCLB Proof-of-concept grant

“x-ray modeling of explosive simulants”, Industrial grant from Iconal

2013

“Further development of code-aperture x-ray phase contrast imaging for commercialization of the method in industrial applications”, Industrial grant form NIKON

 “Three-dimensional quantitative x-ray phase imaging”, EPSRC “Developing Leaders”

 “Laboratory-Based Coded Aperture X-ray Phase Contrast Imaging”, EU-Funded Marie Curie “Career Integration” Grants

 “Maximizing sensitivity and resolution in edge illumination – based X-ray phase-contrast imaging methods”, EU-Funded Marie Curie “Career Integration” Grants

 “Single-Shot, Laboratory-Based Quantitative X-Ray Phase Contrast Imaging through Energy-Resolved pixelated detectors” STFC “Futures” Studentships

2012

 “Evaluation of coded-aperture x-ray phase contrast imaging for commercialization of the method in industrial applications”, Industrial grant form NIKON

 “Taking x-ray phase contrast imaging into mainstream applications”, Royal Society, RS Scientific Discussion Meetings plus Satellite “Theo Murphy” International Scientific Meeting at the Kavli Centre

Retreat grant for the AXIm group, EPSRC, Creativity at Home

2011

“Achieving a step change in osteoarthritis research through innovative imaging tools”, UCL-Imperial “kickstart” grant (A. Olivo co-PI with Dr. Massimo Marenzana, Imperial College)

2010

“Transforming the use of x-rays in science and society”, EPSRC, Challenging Engineering award

2010 “Phase modulation technology for X-ray imaging”, EPSRC, Multidisciplinary research at RCaH (led by Prof. Ian Robinson, UCL Phys. and Astr. – A. Olivo co-I)

2009

 “X-ray phase-contrast breast tomosynthesis”, EPSRC (through DTA) plus Industrial Partner (DEXELA Ltd), PhD Studentship

2007

“A novel phase contrast technique with the potential of revolutionizing x-ray imaging applications in medicine, biology, industry and security”, EPSRC, Career Acceleration Fellowships

 “Development of a novel mammography system based on x-ray phase contrast imaging”, Wellcome Trust, Translation Awards

2006

 “X-ray Phase Contrast Imaging (XPCi) for increased sensitivity and reduced cluttering”, HOSDB, Innovative ideas for explosives and weapons detection R&D

2005

“PC RAD – Towards a clinical implementation of phase contrast radiology”, EU, Marie Curie Intra-European Fellowships