DoM Seminar: Dr Peter Grayson (virtual)

 “Somatic Mutations in Rheumatologic Diseases: VEXAS Syndrome and Beyond”

Dr Peter Grayson
Chief, Vasculitis Translational Research Programme
Acting Director, NIAMS Rheumatology Fellowship Program

Host: Dr Puja Mehta
Clinical Research Fellow in Respiratory Medicine

Thursday 29th September 2022 at 13:00 -14:00
This seminar will be presented in Second Floor Seminar Room of the Rayne Buiding and will also run on Teams (link).
The presenter and host will be logging in virtually and will not be in the room for this presentation

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Dr. Grayson is board-certified in Internal Medicine and Rheumatology. He completed his undergraduate degree from Brown University in 1999, his medical degree from the Medical University of South Carolina in 2004, and a Masters in Science from Boston University in 2008. He served as a Chief Resident in Internal Medicine at Boston Medical Center and completed an additional two-year vasculitis fellowship within the Vasculitis Clinical Research Consortium. 

Currently, an Earl Stadtman Investigator at the NIAMS, Dr. Grayson’s research focuses on clinical and translational research across many forms of systemic vasculitis. Specifically, his work has focused on biomarker discovery/development, the use of advanced molecular imaging, molecular classification of disease, clinical trials, and genetics/genomics of vasculitis. His group has clinically defined the use of advanced molecular imaging as a surrogate marker of vascular inflammation in large-vessel vasculitis.  His group has conducted some of the only translational work related to relapsing polychondritis, including the identification of somatic mutations in UBA1 as a driver of disease in a subset of these patients.  Translational work from the group has also defined novel pathways of neutrophil-mediated inflammation in monogenic vasculitis and drug-induced vasculitis and has identified novel biomarkers of disease activity in many forms of vasculitis that suggest novel therapeutic targets.

Dr. Grayson has a strong commitment to mentoring young investigators in rare disease research. He serves as the Associate Program Director for the NIAMS Rheumatology Fellowship Program and he is the recipient of numerous teaching awards. He is actively involved in leadership roles within the American College of Rheumatology and was a recipient of the American College of Rheumatology’s Distinguished Fellow Award in 2011. He has served on the editorial board for Arthritis & Rheumatology and the Journal of Rheumatology. He currently serves on the Board of Directors for the Vasculitis Foundation and is a Steering Committee member on the Vasculitis Clinical Research Consortium.

• Profile
• 'Somatic Mutations in UBA1 and Severe Adult-Onset Autoinflammatory Disease' 

The seminars are open to UCL & UCLH staff, students and their visitors. Please contact alison.kelly@ucl.ac.uk for all enquires  
Audience members: Please ensure that your mic is muted and video turned off during the talk. There will be a 10-minute Q&A at the end of the talk. Please ensure that you use the ‘raise hand’ function if you would like to ask a question. Thank you.