UCL Division of Medicine


DoM Seminar: Professor Edwin Chilvers

01 December 2022, 1:00 pm–2:00 pm

Edwin photo

"The function and fate of human neutrophils: studies to quantify circulating half-life and lung retention"

This event is free.

Event Information

Open to

UCL staff | UCL students






Alison Kelly – Division of Medicine

 The function and fate of human neutrophils: studies to quantify circulating half-life and lung retention

Professor Edwin Chilvers
Imperial College

Host: Professor Derek Gilroy
Experimental and Translational Medicine

Thursday 1st December 2022 at 13:00 -14:00
This seminar will take place in Second Floor Seminar Room of the Rayne Buiding and will also run on Teams (link)
Lunch will be provided

Edwin was appointed Professor of Medicine and Head of the National Heart and Lung Institute (NHLI) in 2018. His research interests are in inflammatory cell biology, in particular the intracellular signals that regulate the activation and survival of neutrophils and eosinophils. This has translational relevance to a range of inflammatory lung diseases including chronic obstructive pulmonary disease (COPD), asthma and acute lung injury. He has a particular interest in the signalling mechanisms regulating NADPH oxidase function in neutrophils, and the control of neutrophil and eosinophil survival by hypoxia and inflammatory cytokines. His research received continuous MRC and Wellcome Trust support for >25 years. 

Edwin graduated from Nottingham University Medical School and following junior posts at the Hammersmith, St Thomas’ and Royal Brompton Hospitals, NHNN-Queen Square, and Registrar posts at the Hammersmith Hospital, he undertook an MRC Research Training Fellowship with Professor Steve Nahorski at Leicester and Professor Peter Barnes FRS at the NHLI, to study the role of phosphoinositide signalling in airways smooth muscle. He then took up a Lectureship at Edinburgh, working with Professor Chris Haslett, and subsequently a Wellcome Trust Senior Clinical Research Fellowship and Hon Consultant Physician at the Royal Infirmary Hospital, where he focused on the role of PI3-kinase signalling in neutrophil priming and apoptosis. 

Prior to moving to Imperial Professor Chilvers was Professor of Respiratory Medicine at Cambridge, where he helped develop the academic Respiratory Medicine Division within the Department of Medicine and specialist clinical services at Addenbrooke’s Hospital. He also served as NED at the Royal Papworth Hospital and was involved in their decision to relocate to the Cambridge Biomedical Campus. He was elected a Fellow of the Academy of Medical Sciences in 2007, serving on the Academy’s Council between 2013-16, and was President of the British Thoracic Society in 2016-17.  He is a Trustee of Asthma + Lung UK (formerly the British Lung Foundation) and Chair of its Research Committee. He is also Chair of the Board of Trustees for the Association of Physicians and a member of the MRC PMSB.

The seminars are open to UCL & UCLH staff, students and their visitors. Please contact alison.kelly@ucl.ac.uk for all enquires  
Audience members: Please ensure that your mic is muted and video turned off during the talk. There will be a 10-minute Q&A at the end of the talk. Please ensure that you use the ‘raise hand’ function if you would like to ask a question. Thank you.